Beta Amyloid Peptide:Research Paper: Hallucinations and source monitoring in Alzheimer's disease

Hallucinations and source monitoring in Alzheimer's disease

Abstract

Introduction: the source monitoring account has been widely investigated for hallucinations in schizophrenia. According to this account, hallucinations are inner events that are misattributed to another source. Our paper investigated this account for Alzheimer's disease.

Method: we investigated hallucination experiences in participants with Alzheimer's disease and age-matched healthy controls, as well as their source monitoring ability. The assessment of source monitoring included three conditions. In the first condition, participants had to remember whether objects were previously manipulated by themselves or by the experimenter (i.e. reality monitoring). In the second condition, they had to remember whether objects were previously manipulated by a black or white experimenter-gloved hand (i.e. external monitoring). In the third condition, participants had to remember whether they had previously manipulated objects or had imagined having done so (i.e. internal monitoring).

Results: relative to healthy control participants, participants with Alzheimer's disease experienced hallucinations more often and lower hits on source monitoring. Interestingly, significant correlations were only observed between hallucinations and the internal monitoring condition in participants with Alzheimer's disease.

Discussion: hallucinations in Alzheimer's disease seem to be related to the processes of making judgments about the (internal) context in which an event has occurred.

Keywords: Alzheimer's disease; hallucinations; source monitoring.

This article originally appeared in the "https://pubmed.ncbi.nlm.nih.gov/33043861/" and has their copyrights. We do not claim copyright on the content. This information is for research purposes only. This Blog is made available by publishers for educational purposes only as well as to give you general information and a general understanding , not to provide specific advice. By using this blog site you understand that there is no client relationship between you and the Blog publisher. The Blog should not be used as a substitute for competent research advice.