Alzheimer’s Research Papers March 2001

Alzheimer’s Research Papers 

             

Steiner RA, Hohmann JG, Holmes A, Wrenn CC, Cadd G, Juréus A, Clifton DK, Luo M, Gutshall M, Ma SY, Mufson EJ, Crawley JN. Galanin transgenic mice display cognitive and neurochemical deficits characteristic of Alzheimer's disease. Proc Natl Acad Sci U S A. 2001 Mar 27;98(7):4184-9.

Koldamova RP, Lefterov IM, Lefterova MI, Lazo JS. Apolipoprotein A-I directly interacts with amyloid precursor protein and inhibits A beta aggregation and toxicity. Biochemistry. 2001 Mar 27;40(12):3553-60.

El-Agnaf OM, Sheridan JM, Sidera C, Siligardi G, Hussain R, Haris PI, Austen BM. Effect of the disulfide bridge and the C-terminal extension on the oligomerization of the amyloid peptide ABri implicated in familial British dementia. Biochemistry. 2001 Mar 27;40(12):3449-57.

Bonay P, Avila J. Apolipoprotein E4 stimulates sulfation of glycosaminoglycans in neural cells. Biochim Biophys Acta. 2001 Mar 26;1535(3):217-20.

Arnáiz E, Jelic V, Almkvist O, Wahlund LO, Winblad B, Valind S, Nordberg A. Impaired cerebral glucose metabolism and cognitive functioning predict deterioration in mild cognitive impairment. Neuroreport. 2001 Mar 26;12(4):851-5.

Rohn TT, Wong SM, Cotman CW, Cribbs DH. 15-deoxy-delta12,14-prostaglandin J2, a specific ligand for peroxisome proliferator-activated receptor-gamma, induces neuronal apoptosis. Neuroreport. 2001 Mar 26;12(4):839-43.

Bosetti F, Solaini G, Tendi EA, Chikhale EG, Chandrasekaran K, Rapoport SI. Mitochondrial cytochrome c oxidase subunit III is selectively down-regulated by aluminum exposure in PC12S cells. Neuroreport. 2001 Mar 26;12(4):721-4.

Eustache F, Desgranges B, Giffard B, de la Sayette V, Baron JC. Entorhinal cortex disruption causes memory deficit in early Alzheimer's disease as shown by PET. Neuroreport. 2001 Mar 26;12(4):683-5.

Nicoll JA, Martin L, Stewart J, Murray LS, Love S, Kennedy PG. Involvement of apolipoprotein E in herpes simplex encephalitis. Neuroreport. 2001 Mar 26;12(4):695-8.

Leong CC, Syed NI, Lorscheider FL. Retrograde degeneration of neurite membrane structural integrity of nerve growth cones following in vitro exposure to mercury. Neuroreport. 2001 Mar 26;12(4):733-7.

Pasquier F. [Comments on the practice guideline for the diagnosis of Alzheimer's disease] Presse Med. 2001 Mar 24;30(11):540-2.

ANAES (Agence Nationale d'Accréditation et d'Evaluation en Santé). [Practice guideline for the diagnosis of Alzheimer's disease] Presse Med. 2001 Mar 24;30(11):537-9.

García García FJ, Sánchez Ayala MI, Pérez Martín A, Martín Correa E, Marsal Alonso C, Rodríguez Ferrer G, García Colmenero C, Romero Rizos L, Rodríguez Barqueroa MJ, Gutiérrez Avila G. [The prevalence of dementia and its main subtypes in subjects older than 65 years: impact of occupation and education. The Toledo Study] Med Clin (Barc). 2001 Mar 24;116(11):401-7.

McLoughlin DM, Standen CL, Lau KF, Ackerley S, Bartnikas TP, Gitlin JD, Miller CC. The neuronal adaptor protein X11alpha interacts with the copper chaperone for SOD1 and regulates SOD1 activity. J Biol Chem. 2001 Mar 23;276(12):9303-7.

Robertson AG, Banfield MJ, Allen SJ, Dando JA, Mason GG, Tyler SJ, Bennett GS, Brain SD, Clarke AR, Naylor RL, Wilcock GK, Brady RL, Dawbarn D. Identification and structure of the nerve growth factor binding site on TrkA. Biochem Biophys Res Commun. 2001 Mar 23;282(1):131-41.

Louzada PR, Paula Lima AC, de Mello FG, Ferreira ST. Dual role of glutamatergic neurotransmission on amyloid beta(1-42) aggregation and neurotoxicity in embryonic avian retina. Neurosci Lett. 2001 Mar 23;301(1):59-63.

Tehranian R, Hasanvan H, Iverfeldt K, Post C, Schultzberg M. Early induction of interleukin-6 mRNA in the hippocampus and cortex of APPsw transgenic mice Tg2576. Neurosci Lett. 2001 Mar 23;301(1):54-8.

Mudher AK, Yee B, Smith AD, Perry VH. Deafferentation of the hippocampus results in the induction of AT8 positive 'granules' in the rat. Neurosci Lett. 2001 Mar 23;301(1):5-8.

Vidal R, Calero M, Révész T, Plant G, Ghiso J, Frangione B. Sequence, genomic structure and tissue expression of Human BRI3, a member of the BRI gene family. Gene. 2001 Mar 21;266(1-2):95-102.

Geerlings MI, Ruitenberg A, Witteman JC, van Swieten JC, Hofman A, van Duijn CM, Breteler MM, Launer LJ. Reproductive period and risk of dementia in postmenopausal women. JAMA. 2001 Mar 21;285(11):1475-81.

Frenkel D, Kariv N, Solomon B. Generation of auto-antibodies towards Alzheimer's disease vaccination. Vaccine. 2001 Mar 21;19(17-19):2615-9.

Davidsson P, Blennow K, Andreasen N, Eriksson B, Minthon L, Hesse C. Differential increase in cerebrospinal fluid-acetylcholinesterase after treatment with acetylcholinesterase inhibitors in patients with Alzheimer's disease. Neurosci Lett. 2001 Mar 16;300(3):157-60.

Tomizawa K, Omori A, Ohtake A, Sato K, Takahashi M. Tau-tubulin kinase phosphorylates tau at Ser-208 and Ser-210, sites found in paired helical filament-tau. FEBS Lett. 2001 Mar 16;492(3):221-7.

Tuppo EE, Forman LJ, Spur BW, Chan-Ting RE, Chopra A, Cavalieri TA. Sign of lipid peroxidation as measured in the urine of patients with probable Alzheimer's disease. Brain Res Bull. 2001 Mar 15;54(5):565-8.

 

O'Barr SA, Caguioa J, Gruol D, Perkins G, Ember JA, Hugli T, Cooper NR. Neuronal expression of a functional receptor for the C5a complement activation fragment. J Immunol. 2001 Mar 15;166(6):4154-62.

DeKroon RM, Armati PJ. Synthesis and processing of apolipoprotein E in human brain cultures. Glia. 2001 Mar 15;33(4):298-305.

Raghavendra V, Kulkarni SK. Possible antioxidant mechanism in melatonin reversal of aging and chronic ethanol-induced amnesia in plus-maze and passive avoidance memory tasks. Free Radic Biol Med. 2001 Mar 15;30(6):595-602.

Youdim KA, Joseph JA. A possible emerging role of phytochemicals in improving age-related neurological dysfunctions: a multiplicity of effects. Free Radic Biol Med. 2001 Mar 15;30(6):583-94.

Niikura T, Hashimoto Y, Okamoto T, Abe Y, Yasukawa T, Kawasumi M, Hiraki T, Kita Y, Terashita K, Kouyama K, Nishimoto I. Insulin-like growth factor I (IGF-I) protects cells from apoptosis by Alzheimer's V642I mutant amyloid precursor protein through IGF-I receptor in an IGF-binding protein-sensitive manner. J Neurosci. 2001 Mar 15;21(6):1902-10.

Rasmuson S, Andrew R, Näsman B, Seckl JR, Walker BR, Olsson T. Increased glucocorticoid production and altered cortisol metabolism in women with mild to moderate Alzheimer's disease. Biol Psychiatry. 2001 Mar 15;49(6):547-52.

Zubieta JK, Koeppe RA, Frey KA, Kilbourn MR, Mangner TJ, Foster NL, Kuhl DE. Assessment of muscarinic receptor concentrations in aging and Alzheimer disease with [11C]NMPB and PET. Synapse. 2001 Mar 15;39(4):275-87.

Clapp-Lilly KL, Smith MA, Perry G, Duffy LK. Melatonin reduces interleukin secretion in amyloid-beta stressed mouse brain slices. Chem Biol Interact. 2001 Mar 14;134(1):101-7.

Friedland RP, Fritsch T, Smyth KA, Koss E, Lerner AJ, Chen CH, Petot GJ, Debanne SM. Patients with Alzheimer's disease have reduced activities in midlife compared with healthy control-group members. Proc Natl Acad Sci U S A. 2001 Mar 13;98(6):3440-5.

Reiman EM, Caselli RJ, Chen K, Alexander GE, Bandy D, Frost J. Declining brain activity in cognitively normal apolipoprotein E epsilon 4 heterozygotes: A foundation for using positron emission tomography to efficiently test treatments to prevent Alzheimer's disease. Proc Natl Acad Sci U S A. 2001 Mar 13;98(6):3334-9.

Lobotesis K, Fenwick JD, Phipps A, Ryman A, Swann A, Ballard C, McKeith IG, O'Brien JT. Occipital hypoperfusion on SPECT in dementia with Lewy bodies but not AD. Neurology. 2001 Mar 13;56(5):643-9.

Kirschenbaum F, Hsu SC, Cordell B, McCarthy JV. Substitution of a glycogen synthase kinase-3beta phosphorylation site in presenilin 1 separates presenilin function from beta-catenin signaling. J Biol Chem. 2001 Mar 9;276(10):7366-75.

 

Yu WH, Lukiw WJ, Bergeron C, Niznik HB, Fraser PE. Metallothionein III is reduced in Alzheimer's disease. Brain Res. 2001 Mar 9;894(1):37-45.

Apelt J, Schliebs R. Beta-amyloid-induced glial expression of both pro- and anti-inflammatory cytokines in cerebral cortex of aged transgenic Tg2576 mice with Alzheimer plaque pathology. Brain Res. 2001 Mar 9;894(1):21-30.

Steiner H, Revesz T, Neumann M, Romig H, Grim MG, Pesold B, Kretzschmar HA, Hardy J, Holton JL, Baumeister R, Houlden H, Haass C. A pathogenic presenilin-1 deletion causes abberrant Abeta 42 production in the absence of congophilic amyloid plaques. J Biol Chem. 2001 Mar 9;276(10):7233-9. ,

 

Menzer G, Müller-Thomsen T, Meins W, Alberici A, Binetti G, Hock C, Nitsch RM, Stoppe G, Reiss J, Finckh U. Non-replication of association between cathepsin D genotype and late onset Alzheimer disease. Am J Med Genet. 2001 Mar 8;105(2):179-82. ,

Dong J, Peters-Libeu CA, Weisgraber KH, Segelke BW, Rupp B, Capila I, Hernáiz MJ, LeBrun LA, Linhardt RJ. Interaction of the N-terminal domain of apolipoprotein E4 with heparin. Biochemistry. 2001 Mar 6;40(9):2826-34.

Culmsee C, Bondada S, Mattson MP. Hippocampal neurons of mice deficient in DNA-dependent protein kinase exhibit increased vulnerability to DNA damage, oxidative stress and excitotoxicity. Brain Res Mol Brain Res. 2001 Mar 5;87(2):257-62.

Jack C, Berezovska O, Wolfe MS, Hyman BT. Effect of PS1 deficiency and an APP gamma-secretase inhibitor on Notch1 signaling in primary mammalian neurons. Brain Res Mol Brain Res. 2001 Mar 5;87(2):166-74.

Murphy T, Yip A, Brayne C, Easton D, Evans JG, Xuereb J, Cairns N, Esiri MM, Rubinsztein DC. The BACE gene: genomic structure and candidate gene study in late-onset Alzheimer's disease. Neuroreport. 2001 Mar 5;12(3):631-4. ,

Kim SH, Cairns N, Fountoulakisc M, Lubec G. Decreased brain histamine-releasing factor protein in patients with Down syndrome and Alzheimer's disease. Neurosci Lett. 2001 Mar 2;300(1):41-4.

Su Y, Chang PT. Acidic pH promotes the formation of toxic fibrils from beta-amyloid peptide. Brain Res. 2001 Mar 2;893(1-2):287-91.

Qiu X, Chen Y, Zhou M. Two point mutations in mitochondrial DNA of cytochrome c oxidase coexist with normal mtDNA in a patient with Alzheimer's disease. Brain Res. 2001 Mar 2;893(1-2):261-3.

Mathieu-Kia AM, Fan LQ, Kreek MJ, Simon EJ, Hiller JM. Mu-, delta- and kappa-opioid receptor populations are differentially altered in distinct areas of postmortem brains of Alzheimer's disease patients. Brain Res. 2001 Mar 2;893(1-2):121-34.

Fraser PE, Darabie AA, McLaurin JA. Amyloid-beta interactions with chondroitin sulfate-derived monosaccharides and disaccharides. implications for drug development. J Biol Chem. 2001 Mar 2;276(9):6412-9.

Hedin HL, Nilsson L, Fowler CJ. Effects of staurosporine, U-73122, wortmannin, 4-hydroxynonenal and sodium azide upon the release of secreted beta-amyloid precursor protein from human platelets in response to thrombin stimulation. Mol Cell Biochem. 2001 Mar;219(1-2):145-52.

Shimohama S. [Aberrant phosphoinositide metabolism in Alzheimer's disease] Nippon Rinsho. 2001 Mar;59 Suppl 3:818-22.

Mori S. [Apolipoprotein E4 and Alzheimer's disease] Nippon Rinsho. 2001 Mar;59 Suppl 3:812-7.

Hyman BT. Molecular and anatomical studies in Alzheimer's disease. Neurologia. 2001 Mar;16(3):100-4.

Ma W, Zheng WH, Belanger S, Kar S, Quirion R. Effects of amyloid peptides on cell viability and expression of neuropeptides in cultured rat dorsal root ganglion neurons: a role for free radicals and protein kinase C. Eur J Neurosci. 2001 Mar;13(6):1125-35.

Bowirrat A, Treves TA, Friedland RP, Korczyn AD. Prevalence of Alzheimer's type dementia in an elderly Arab population. Eur J Neurol. 2001 Mar;8(2):119-23.

Høgh P, Knudsen GM, Kjaer KH, Jørgensen OS, Paulson OB, Waldemar G. Single photon emission computed tomography and apolipoprotein E in Alzheimer's disease: impact of the epsilon4 allele on regional cerebral blood flow. J Geriatr Psychiatry Neurol. 2001 Spring;14(1):42-51.

Schröder J, Buchsbaum MS, Shihabuddin L, Tang C, Wei TC, Spiegel-Cohen J, Hazlett EA, Abel L, Luu-Hsia C, Ciaravolo TM, Marin D, Davis KL. Patterns of cortical activity and memory performance in Alzheimer's disease. Biol Psychiatry. 2001 Mar 1;49(5):426-36.

Tekin S, Mega MS, Masterman DM, Chow T, Garakian J, Vinters HV, Cummings JL. Orbitofrontal and anterior cingulate cortex neurofibrillary tangle burden is associated with agitation in Alzheimer disease. Ann Neurol. 2001 Mar;49(3):355-61.

Campbell A. beta-amyloid: friend or foe. Med Hypotheses. 2001 Mar;56(3):388-91.

Dreon DM, Peroutkal SJ. Medical utility of apoe allele determination in assessing the need for antioxidant therapy. Med Hypotheses. 2001 Mar;56(3):357-9.

Asahina M, Yoshiyama Y, Hattori T. Expression of matrix metalloproteinase-9 and urinary-type plasminogen activator in Alzheimer's disease brain. Clin Neuropathol. 2001 Mar-Apr;20(2):60-3.

Mak W, Ho SL. The impact of molecular biology on clinical neurology. Hong Kong Med J. 2001 Mar;7(1):40-9.

Sekine-Aizawa Y, Hama E, Watanabe K, Tsubuki S, Kanai-Azuma M, Kanai Y, Arai H, Aizawa H, Iwata N, Saido TC. Matrix metalloproteinase (MMP) system in brain: identification and characterization of brain-specific MMP highly expressed in cerebellum. Eur J Neurosci. 2001 Mar;13(5):935-48.

Paschen W, Mengesdorf T, Althausen S, Hotop S. Peroxidative stress selectively down-regulates the neuronal stress response activated under conditions of endoplasmic reticulum dysfunction. J Neurochem. 2001 Mar;76(6):1916-24.

Asanuma M, Nishibayashi-Asanuma S, Miyazaki I, Kohno M, Ogawa N. Neuroprotective effects of non-steroidal anti-inflammatory drugs by direct scavenging of nitric oxide radicals. J Neurochem. 2001 Mar;76(6):1895-904.

Ho MC, Lo AC, Kurihara H, Yu AC, Chung SS, Chung SK. Endothelin-1 protects astrocytes from hypoxic/ischemic injury. FASEB J. 2001 Mar;15(3):618-26.

Jo DG, Kim MJ, Choi YH, Kim IK, Song YH, Woo HN, Chung CW, Jung YK. Pro-apoptotic function of calsenilin/DREAM/KChIP3. FASEB J. 2001 Mar;15(3):589-91.

 

Schild L, Keilhoff G, Augustin W, Reiser G, Striggow F. Distinct Ca2+ thresholds determine cytochrome c release or permeability transition pore opening in brain mitochondria. FASEB J. 2001 Mar;15(3):565-7.

 

Jellinger KA. Small concomitant cerebrovascular lesions are not important for cognitive decline in severe Alzheimer disease. Arch Neurol. 2001 Mar;58(3):520-1.

Mackenzie IR, Munoz DG. Effect of anti-inflammatory medications on neuropathological findings in Alzheimer disease. Arch Neurol. 2001 Mar;58(3):517-9.

Brenner SR. Lower incidence of Alzheimer disease in an Indian community compared with an American community. Arch Neurol. 2001 Mar;58(3):517.

Ho L, Purohit D, Haroutunian V, Luterman JD, Willis F, Naslund J, Buxbaum JD, Mohs RC, Aisen PS, Pasinetti GM. Neuronal cyclooxygenase 2 expression in the hippocampal formation as a function of the clinical progression of Alzheimer disease. Arch Neurol. 2001 Mar;58(3):487-92.

Bokde AL, Pietrini P, Ibáñez V, Furey ML, Alexander GE, Graff-Radford NR, Rapoport SI, Schapiro MB, Horwitz B. The effect of brain atrophy on cerebral hypometabolism in the visual variant of Alzheimer disease. Arch Neurol. 2001 Mar;58(3):480-6.

Sweet RA, Hamilton RL, Healy MT, Wisniewski SR, Henteleff R, Pollock BG, Lewis DA, DeKosky ST. Alterations of striatal dopamine receptor binding in Alzheimer disease are associated with Lewy body pathology and antemortem psychosis. Arch Neurol. 2001 Mar;58(3):466-72.

Stern Y, Jacobs D, Goldman J, Gomez-Tortosa E, Hyman BT, Liu Y, Troncoso J, Marder K, Tang MX, Brandt J, Albert M. An investigation of clinical correlates of Lewy bodies in autopsy-proven Alzheimer disease. Arch Neurol. 2001 Mar;58(3):460-5.

Doody RS, Massman P, Dunn JK. A method for estimating progression rates in Alzheimer disease. Arch Neurol. 2001 Mar;58(3):449-54.

Borroni B, Colciaghi F, Pastorino L, Pettenati C, Cottini E, Rozzini L, Monastero R, Lenzi GL, Cattabeni F, Di Luca M, Padovani A. Amyloid precursor protein in platelets of patients with Alzheimer disease: effect of acetylcholinesterase inhibitor treatment. Arch Neurol. 2001 Mar;58(3):442-6. ,

Seshadri S, Zornberg GL, Derby LE, Myers MW, Jick H, Drachman DA. Postmenopausal estrogen replacement therapy and the risk of Alzheimer disease. Arch Neurol. 2001 Mar;58(3):435-40.

Doody RS, Geldmacher DS, Gordon B, Perdomo CA, Pratt RD, Donepezil Study Group. Open-label, multicenter, phase 3 extension study of the safety and efficacy of donepezil in patients with Alzheimer disease. Arch Neurol. 2001 Mar;58(3):427-33.

Farlow MR, Hake A, Messina J, Hartman R, Veach J, Anand R. Response of patients with Alzheimer disease to rivastigmine treatment is predicted by the rate of disease progression. Arch Neurol. 2001 Mar;58(3):417-22.

Bozoki A, Giordani B, Heidebrink JL, Berent S, Foster NL. Mild cognitive impairments predict dementia in nondemented elderly patients with memory loss. Arch Neurol. 2001 Mar;58(3):411-6.

  

Morris JC, Storandt M, Miller JP, McKeel DW, Price JL, Rubin EH, Berg L. Mild cognitive impairment represents early-stage Alzheimer disease. Arch Neurol. 2001 Mar 1;58(3):397-405. ,

 

Lovell MA, Markesbery WR. Ratio of 8-hydroxyguanine in intact DNA to free 8-hydroxyguanine is increased in Alzheimer disease ventricular cerebrospinal fluid. Arch Neurol. 2001 Mar;58(3):392-6. ,

Poorkaj P, Grossman M, Steinbart E, Payami H, Sadovnick A, Nochlin D, Tabira T, Trojanowski JQ, Borson S, Galasko D, Reich S, Quinn B, Schellenberg G, Bird TD. Frequency of tau gene mutations in familial and sporadic cases of non-Alzheimer dementia. Arch Neurol. 2001 Mar 1;58(3):383-7. ,

Andreasen N, Minthon L, Davidsson P, Vanmechelen E, Vanderstichele H, Winblad B, Blennow K. Evaluation of CSF-tau and CSF-Abeta42 as diagnostic markers for Alzheimer disease in clinical practice. Arch Neurol. 2001 Mar;58(3):373-9. ,

Diaz-Arrastia R, Baskin F. New biochemical markers in Alzheimer disease. Arch Neurol. 2001 Mar;58(3):354-6.

Knopman D. Cerebrospinal fluid beta-amyloid and tau proteins for the diagnosis of Alzheimer disease. Arch Neurol. 2001 Mar;58(3):349-50.

Huang F, Li W, Zhang B, Cui X, Han Z, Fang Z, Cai S, Yin L, Wang L. Effects of free radicals and amyloid beta protein on the currents of expressed rat receptors in Xenopus oocytes. Chin Med J (Engl). 2001 Mar;114(3):244-7.

Czyzewski K, Pfeffer A, Wasiak B, Luczywek E, Golebiowski M, Styczynska M, Barcikowska M. [Vascular risk factors in demented elderly: analysis of Alzheimer Clinic materials] Neurol Neurochir Pol. 2001 Mar-Apr;35(3):405-13.

Orth M, Schapira AH. Mitochondria and degenerative disorders. Am J Med Genet. 2001 Spring;106(1):27-36.

Kulczycki J, Bertrand E, Lojkowska W, Dowjat W, Wisniewski T, Lyczywek-Zwierz M. [Familial Alzheimer's disease connected with mutation in presenilin gene 1 (P117L)] Neurol Neurochir Pol. 2001 Mar-Apr;35(2):213-24.

Qu T, Manev R, Manev H. 5-Lipoxygenase (5-LOX) promoter polymorphism in patients with early-onset and late-onset Alzheimer's disease. J Neuropsychiatry Clin Neurosci. 2001 Spring;13(2):304-5.

Dandrea MR, Reiser PA, Gumula NA, Hertzog BM, Andrade-Gordon P. Application of triple immunohistochemistry to characterize amyloid plaque-associated inflammation in brains with Alzheimer's disease. Biotech Histochem. 2001 Mar;76(2):97-106.

Bachurin SO. [Medicinal and chemical approaches to focused search of agents for treatment and therapy of Alzheimer disease] Vopr Med Khim. 2001 Mar-Apr;47(2):155-97.

Grunwald M, Busse F, Hensel A, Kruggel F, Riedel-Heller S, Wolf H, Arendt T, Gertz HJ. Correlation between cortical theta activity and hippocampal volumes in health, mild cognitive impairment, and mild dementia. J Clin Neurophysiol. 2001 Mar;18(2):178-84.

Hermon C, Alberman E, Beral V, Swerdlow AJ. Mortality and cancer incidence in persons with Down's syndrome, their parents and siblings. Ann Hum Genet. 2001 Mar;65(Pt 2):167-76.

Michel JP, Gold G. Behavioural symptoms in Alzheimer's disease: validity of targets and present treatments. Age Ageing. 2001 Mar;30(2):105-6.

Shcherbatykh TV, Kiryanov SA, Korovaitseva GI, Selezneva ND, Voskresenskaya NI, Golimbet VE, Farrer L, Gavrilova SI, Rogaev EI. The angiotensin-converting enzyme gene as a possible risk or protective factor in Alzheimer's disease. Neurosci Behav Physiol. 2001 Mar-Apr;31(2):179-81. , ,

Zakharov VV, Akhutina TV, Yakhno NN. Memory impairment in Parkinson's disease. Neurosci Behav Physiol. 2001 Mar-Apr;31(2):157-63.

Salamanca-Gómez F. [A new susceptibility gene in Alzheimer's disease] Gac Med Mex. 2001 Mar-Apr;137(2):175-6.

Nilsson LN, Bales KR, DiCarlo G, Gordon MN, Morgan D, Paul SM, Potter H. Alpha-1-antichymotrypsin promotes beta-sheet amyloid plaque deposition in a transgenic mouse model of Alzheimer's disease. J Neurosci. 2001 Mar 1;21(5):1444-51. ,

Yip CM, McLaurin J. Amyloid-beta peptide assembly: a critical step in fibrillogenesis and membrane disruption. Biophys J. 2001 Mar;80(3):1359-71.

Winocur G, Roder J, Lobaugh N. Learning and memory in S100-beta transgenic mice: an analysis of impaired and preserved function. Neurobiol Learn Mem. 2001 Mar;75(2):230-43.

Shoji M, Kanai M, Matsubara E, Tomidokoro Y, Shizuka M, Ikeda Y, Ikeda M, Harigaya Y, Okamoto K, Hirai S. The levels of cerebrospinal fluid Abeta40 and Abeta42(43) are regulated age-dependently. Neurobiol Aging. 2001 Mar-Apr;22(2):209-15.

Lovell MA, Xie C, Markesbery WR. Acrolein is increased in Alzheimer's disease brain and is toxic to primary hippocampal cultures. Neurobiol Aging. 2001 Mar-Apr;22(2):187-94. ,

Sandberg G, Stewart W, Smialek J, Troncoso JC. The prevalence of the neuropathological lesions of Alzheimer's disease is independent of race and gender. Neurobiol Aging. 2001 Mar-Apr;22(2):169-75.

Wise PM, Dubal DB, Wilson ME, Rau SW, Böttner M. Minireview: neuroprotective effects of estrogen-new insights into mechanisms of action. Endocrinology. 2001 Mar;142(3):969-73.

Mallender WD, Yager D, Onstead L, Nichols MR, Eckman C, Sambamurti K, Kopcho LM, Marcinkeviciene J, Copeland RA, Rosenberry TL. Characterization of recombinant, soluble beta-secretase from an insect cell expression system. Mol Pharmacol. 2001 Mar;59(3):619-26.

Kawano M, Ichimiya A, Ogomori K, Kuwabara Y, Sasaki M, Yoshida T, Tashiro N. Relationship between both IQ and Mini-Mental State Examination and the regional cerebral glucose metabolism in clinically diagnosed Alzheimer's disease: a PET study. Dement Geriatr Cogn Disord. 2001 Mar-Apr;12(2):171-6.

Nebu A, Ikeda M, Fukuhara R, Komori K, Maki N, Hokoishi K, Shigenobu K, Kikuchi T, Tanabe H. Utility of (99m)Tc-HM-PAO SPECT hippocampal image to diagnose early stages of Alzheimer's disease using semiquantitative analysis. Dement Geriatr Cogn Disord. 2001 Mar-Apr;12(2):153-7.

Leuba G, Saini K, Zimmermann V, Giannakopoulos P, Bouras C. Mild amyloid pathology in the primary visual system of nonagenarians and centenarians. Dement Geriatr Cogn Disord. 2001 Mar-Apr;12(2):146-52.

Lesser G, Kandiah K, Libow LS, Likourezos A, Breuer B, Marin D, Mohs R, Haroutunian V, Neufeld R. Elevated serum total and LDL cholesterol in very old patients with Alzheimer's disease. Dement Geriatr Cogn Disord. 2001 Mar-Apr;12(2):138-45. ,

McCaddon A, Hudson P, Abrahamsson L, Olofsson H, Regland B. Analogues, ageing and aberrant assimilation of vitamin B12 in Alzheimer's disease. Dement Geriatr Cogn Disord. 2001 Mar-Apr;12(2):133-7. ,

Blomberg M, Jensen M, Basun H, Lannfelt L, Wahlund LO. Cerebrospinal fluid tau levels increase with age in healthy individuals. Dement Geriatr Cogn Disord. 2001 Mar-Apr;12(2):127-32. ,

Yamada M, Itoh Y, Sodeyama N, Suematsu N, Otomo E, Matsushita M, Mizusawa H. Senile dementia of the neurofibrillary tangle type: a comparison with Alzheimer's disease. Dement Geriatr Cogn Disord. 2001 Mar-Apr;12(2):117-26.

Braunewell K, Riederer P, Spilker C, Gundelfinger ED, Bogerts B, Bernstein HG. Abnormal localization of two neuronal calcium sensor proteins, visinin-like proteins (vilips)-1 and -3, in neocortical brain areas of Alzheimer disease patients. Dement Geriatr Cogn Disord. 2001 Mar-Apr;12(2):110-6.

Matsubara M, Yamagata H, Kamino K, Nomura T, Kohara K, Kondo I, Miki T. Genetic association between Alzheimer disease and the alpha-synuclein gene. Dement Geriatr Cogn Disord. 2001 Mar-Apr;12(2):106-9. ,

Eckert A, Oster M, Zerfass R, Hennerici M, Müller WE. Elevated levels of fragmented DNA nucleosomes in native and activated lymphocytes indicate an enhanced sensitivity to apoptosis in sporadic Alzheimer's disease. Specific differences to vascular dementia. Dement Geriatr Cogn Disord. 2001 Mar-Apr;12(2):98-105.

Nobili F, Copello F, Buffoni F, Vitali P, Girtler N, Bordoni C, Safaie-Semnani E, Mariani G, Rodriguez G. Regional cerebral blood flow and prognostic evaluation in Alzheimer's disease. Dement Geriatr Cogn Disord. 2001 Mar-Apr;12(2):89-97.

Aerssens J, Raeymaekers P, Lilienfeld S, Geerts H, Konings F, Parys W. APOE genotype: no influence on galantamine treatment efficacy nor on rate of decline in Alzheimer's disease. Dement Geriatr Cogn Disord. 2001 Mar-Apr;12(2):69-77.

Scacchi R, Gambina G, Martini MC, Ruggeri M, Ferrari G, Silvestri M, Schiavon R, Corbo RM. Polymorphisms of the apolipoprotein E gene regulatory region and of the LDL receptor gene in late-onset Alzheimer's disease in relation to the plasma lipidic pattern. Dement Geriatr Cogn Disord. 2001 Mar-Apr;12(2):63-8. ,

Yamagata K, Urakami K, Ikeda K, Ji Y, Adachi Y, Arai H, Sasaki H, Sato K, Nakashima K. High expression of apolipoprotein E mRNA in the brains with sporadic Alzheimer's disease. Dement Geriatr Cogn Disord. 2001 Mar-Apr;12(2):57-62. , ,

Muma NA, Lee JM, Gorman L, Heidenreich BA, Mitrovic I, Napier TC. 6-hydroxydopamine-induced lesions of dopaminergic neurons alter the function of postsynaptic cholinergic neurons without changing cytoskeletal proteins. Exp Neurol. 2001 Mar;168(1):135-43.

Chen M, Fernandez HL. Where do Alzheimer's plaques and tangles come from? Aging-induced protein degradation inefficiency. Front Biosci. 2001 Mar 1;6:E1-E11.

 

  

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Albert SM, Jacobs DM, Sano M, Marder K, Bell K, Devanand D, Brandt J, Albert M, Stern Y. Longitudinal study of quality of life in people with advanced Alzheimer's disease. Am J Geriatr Psychiatry. 2001 Spring;9(2):160-8.

Baron-Ruppert G, Luepke NP. Evidence for toxic effects of alkylphenols from Ginkgo biloba in the hen's egg test (HET). Phytomedicine. 2001 Mar;8(2):133-8.

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