2001: July: Alzheimer’s Research Papers

2001: July: Alzheimer’s Research Papers    

           

Wittmann CW, Wszolek MF, Shulman JM, Salvaterra PM, Lewis J, Hutton M, Feany MB. Tauopathy in Drosophila: neurodegeneration without neurofibrillary tangles. Science. 2001 Jul 27;293(5530):711-4. ,

    

Evin G, Sharples RA, Weidemann A, Reinhard FB, Carbone V, Culvenor JG, Holsinger RM, Sernee MF, Beyreuther K, Masters CL. Aspartyl protease inhibitor pepstatin binds to the presenilins of Alzheimer's disease. Biochemistry. 2001 Jul 27;40(28):8359-68.

Gordon DJ, Sciarretta KL, Meredith SC. Inhibition of beta-amyloid(40) fibrillogenesis and disassembly of beta-amyloid(40) fibrils by short beta-amyloid congeners containing N-methyl amino acids at alternate residues. Biochemistry. 2001 Jul 27;40(28):8237-45.

Suzuki K, Miura T, Takeuchi H. Inhibitory effect of copper(II) on zinc(II)-induced aggregation of amyloid beta-peptide. Biochem Biophys Res Commun. 2001 Jul 27;285(4):991-6.

Kozin SA, Zirah S, Rebuffat S, Hoa GH, Debey P. Zinc binding to Alzheimer's Abeta(1-16) peptide results in stable soluble complex. Biochem Biophys Res Commun. 2001 Jul 27;285(4):959-64.

Rüb U, Schultz C, Del Tredici K, Braak H. Early involvement of the tegmentopontine reticular nucleus during the evolution of Alzheimer's disease-related cytoskeletal pathology. Brain Res. 2001 Jul 27;908(2):107-12.

Kim KW, Jhoo JH, Lee JH, Lee DY, Lee KU, Youn JY, Woo JI. Transferrin C2 variant does not confer a risk for Alzheimer's disease in Koreans. Neurosci Lett. 2001 Jul 27;308(1):45-8. ,

Savaskan E, Olivieri G, Brydon L, Jockers R, Kräuchi K, Wirz-Justice A, Müller-Spahn F. Cerebrovascular melatonin MT1-receptor alterations in patients with Alzheimer's disease. Neurosci Lett. 2001 Jul 27;308(1):9-12.

Maruyama H, Izumi Y, Oda M, Torii T, Morino H, Toji H, Sasaki K, Terasawa H, Nakamura S, Kawakami H. Lack of an association between cystatin C gene polymorphisms in Japanese patients with Alzheimer's disease. Neurology. 2001 Jul 24;57(2):337-9. ,

Roks G, Cruts M, Slooter AJ, Dermaut B, Hofman A, van Broeckhoven C, van Duijn CM. The cystatin C polymorphism is not associated with early onset Alzheimer's disease. Neurology. 2001 Jul 24;57(2):366-7. ,

Kremer JJ, Sklansky DJ, Murphy RM. Profile of changes in lipid bilayer structure caused by beta-amyloid peptide. Biochemistry. 2001 Jul 24;40(29):8563-71.

Galton CJ, Patterson K, Graham K, Lambon-Ralph MA, Williams G, Antoun N, Sahakian BJ, Hodges JR. Differing patterns of temporal atrophy in Alzheimer's disease and semantic dementia. Neurology. 2001 Jul 24;57(2):216-25.

Fox NC, Crum WR, Scahill RI, Stevens JM, Janssen JC, Rossor MN. Imaging of onset and progression of Alzheimer's disease with voxel-compression mapping of serial magnetic resonance images. Lancet. 2001 Jul 21;358(9277):201-5.

O'Brien JT, Ballard CG. Drugs for Alzheimer's disease. BMJ. 2001 Jul 21;323(7305):123-4.

Park IH, Jung MW, Mori H, Mook-Jung I. Zinc enhances synthesis of presenilin 1 in mouse primary cortical culture. Biochem Biophys Res Commun. 2001 Jul 20;285(3):680-8.

Lebeau A, Esclaire F, Rostène W, Pélaprat D. Baicalein protects cortical neurons from beta-amyloid (25-35) induced toxicity. Neuroreport. 2001 Jul 20;12(10):2199-202.

Tsang MC, Lo AC, Cheung PT, Chung SS, Chung SK. Perinatal hypoxia-/ischemia-induced endothelin-1 mRNA in astrocyte-like and endothelial cells. Neuroreport. 2001 Jul 20;12(10):2265-70.

Kuusisto E, Salminen A, Alafuzoff I. Ubiquitin-binding protein p62 is present in neuronal and glial inclusions in human tauopathies and synucleinopathies. Neuroreport. 2001 Jul 20;12(10):2085-90.

Sung JY, Kim J, Paik SR, Park JH, Ahn YS, Chung KC. Induction of neuronal cell death by Rab5A-dependent endocytosis of alpha-synuclein. J Biol Chem. 2001 Jul 20;276(29):27441-8.

Quintas A, Vaz DC, Cardoso I, Saraiva MJ, Brito RM. Tetramer dissociation and monomer partial unfolding precedes protofibril formation in amyloidogenic transthyretin variants. J Biol Chem. 2001 Jul 20;276(29):27207-13.

Brayden DJ, Templeton L, McClean S, Barbour R, Huang J, Nguyen M, Ahern D, Motter R, Johnson-Wood K, Vasquez N, Schenk D, Seubert P. Encapsulation in biodegradable microparticles enhances serum antibody response to parenterally-delivered beta-amyloid in mice. Vaccine. 2001 Jul 20;19(30):4185-93.

Ji D, Lape R, Dani JA. Timing and location of nicotinic activity enhances or depresses hippocampal synaptic plasticity. Neuron. 2001 Jul 19;31(1):131-41.

Huang Y, Liu XQ, Wyss-Coray T, Brecht WJ, Sanan DA, Mahley RW. Apolipoprotein E fragments present in Alzheimer's disease brains induce neurofibrillary tangle-like intracellular inclusions in neurons. Proc Natl Acad Sci U S A. 2001 Jul 17;98(15):8838-43.

Bi X, Yong AP, Zhou J, Ribak CE, Lynch G. Rapid induction of intraneuronal neurofibrillary tangles in apolipoprotein E-deficient mice. Proc Natl Acad Sci U S A. 2001 Jul 17;98(15):8832-7.

  

Demattos RB, Bales KR, Cummins DJ, Dodart JC, Paul SM, Holtzman DM. Peripheral anti-A beta antibody alters CNS and plasma A beta clearance and decreases brain A beta burden in a mouse model of Alzheimer's disease. Proc Natl Acad Sci U S A. 2001 Jul 17;98(15):8850-5.

 

DeFreitas MF, McQuillen PS, Shatz CJ. A novel p75NTR signaling pathway promotes survival, not death, of immunopurified neocortical subplate neurons. J Neurosci. 2001 Jul 15;21(14):5121-9.

Castellani RJ, Harris PL, Sayre LM, Fujii J, Taniguchi N, Vitek MP, Founds H, Atwood CS, Perry G, Smith MA. Active glycation in neurofibrillary pathology of Alzheimer disease: N(epsilon)-(carboxymethyl) lysine and hexitol-lysine. Free Radic Biol Med. 2001 Jul 15;31(2):175-80.

Mudher A, Chapman S, Richardson J, Asuni A, Gibb G, Pollard C, Killick R, Iqbal T, Raymond L, Varndell I, Sheppard P, Makoff A, Gower E, Soden PE, Lewis P, Murphy M, Golde TE, Rupniak HT, Anderton BH, Lovestone S. Dishevelled regulates the metabolism of amyloid precursor protein via protein kinase C/mitogen-activated protein kinase and c-Jun terminal kinase. J Neurosci. 2001 Jul 15;21(14):4987-95.

Pedersen WA, Wan R, Mattson MP. Impact of aging on stress-responsive neuroendocrine systems. Mech Ageing Dev. 2001 Jul 15;122(9):963-83.

Kametani F, Tanaka K, Usami M, Maruyama K, Mori H. Human wild presenilin-1 mimics the effect of the mutant presenilin-1 on the processing of Alzheimer's amyloid precursor protein in PC12D cells. J Neurol Sci. 2001 Jul 15;188(1-2):27-31.

Bamberger ME, Landreth GE. Microglial interaction with beta-amyloid: implications for the pathogenesis of Alzheimer's disease. Microsc Res Tech. 2001 Jul 15;54(2):59-70.

Butterfield DA, Kanski J. Brain protein oxidation in age-related neurodegenerative disorders that are associated with aggregated proteins. Mech Ageing Dev. 2001 Jul 15;122(9):945-62.

Hanyu H, Asano T, Sakurai H, Takasaki M, Shindo H, Abe K. Magnetization transfer measurements of the hippocampus in the early diagnosis of Alzheimer's disease. J Neurol Sci. 2001 Jul 15;188(1-2):79-84.

Baskys A, Adamchik Y. Neuroprotective effects of extracellular glutamate are absent in hippocampal organotypic cultures treated with the amyloid peptide Abeta(25-35). Brain Res. 2001 Jul 13;907(1-2):188-94.

Town T, Tan J, Sansone N, Obregon D, Klein T, Mullan M. Characterization of murine immunoglobulin G antibodies against human amyloid-beta1-42. Neurosci Lett. 2001 Jul 13;307(2):101-4.

Ramirez MJ, Heslop KE, Francis PT, Rattray M. Expression of amyloid precursor protein, tau and presenilin RNAs in rat hippocampus following deafferentation lesions. Brain Res. 2001 Jul 13;907(1-2):222-32.

Frackowiak J, Mazur-Kolecka B, Kaczmarski W, Dickson D. Deposition of Alzheimer's vascular amyloid-beta is associated with decreased expression of brain L-3-hydroxyacyl-coenzyme A dehydrogenase (ERAB). Brain Res. 2001 Jul 13;907(1-2):44-53.

Schönknecht P, Pantel J, Klinga K, Jensen M, Hartmann T, Salbach B, Schröder J. Reduced cerebrospinal fluid estradiol levels are associated with increased beta-amyloid levels in female patients with Alzheimer's disease. Neurosci Lett. 2001 Jul 13;307(2):122-4.

Iwata K, Eyles SJ, Lee JP. Exposing asymmetry between monomers in Alzheimer's amyloid fibrils via reductive alkylation of lysine residues. J Am Chem Soc. 2001 Jul 11;123(27):6728-9.

Jobling MF, Huang X, Stewart LR, Barnham KJ, Curtain C, Volitakis I, Perugini M, White AR, Cherny RA, Masters CL, Barrow CJ, Collins SJ, Bush AI, Cappai R. Copper and zinc binding modulates the aggregation and neurotoxic properties of the prion peptide PrP106-126. Biochemistry. 2001 Jul 10;40(27):8073-84.

Bhattacharya K, Rank KB, Evans DB, Sharma SK. Role of cysteine-291 and cysteine-322 in the polymerization of human tau into Alzheimer-like filaments. Biochem Biophys Res Commun. 2001 Jul 6;285(1):20-6.

Cao X, Südhof TC. A transcriptionally [correction of transcriptively] active complex of APP with Fe65 and histone acetyltransferase Tip60. Science. 2001 Jul 6;293(5527):115-20.

    

Kakio A, Nishimoto SI, Yanagisawa K, Kozutsumi Y, Matsuzaki K. Cholesterol-dependent formation of GM1 ganglioside-bound amyloid beta-protein, an endogenous seed for Alzheimer amyloid. J Biol Chem. 2001 Jul 6;276(27):24985-90.

 

Eckman EA, Reed DK, Eckman CB. Degradation of the Alzheimer's amyloid beta peptide by endothelin-converting enzyme. J Biol Chem. 2001 Jul 6;276(27):24540-8.

 

Allsop D, Swanson L, Moore S, Davies Y, York A, El-Agnaf OM, Soutar I. Fluorescence anisotropy: a method for early detection of Alzheimer beta-peptide (Abeta) aggregation. Biochem Biophys Res Commun. 2001 Jul 6;285(1):58-63.

Molero AE, Pino-Ramírez G, Maestre GE. Modulation by age and gender of risk for Alzheimer's disease and vascular dementia associated with the apolipoprotein E-varepsilon4 allele in Latin Americans: findings from the Maracaibo Aging Study. Neurosci Lett. 2001 Jul 6;307(1):5-8.

Lee CW, Zhuang ZP, Kung MP, Plössl K, Skovronsky D, Gur T, Hou C, Trojanowski JQ, Lee VM, Kung HF. Isomerization of (Z,Z) to (E,E)1-bromo-2,5-bis-(3-hydroxycarbonyl-4-hydroxy)styrylbenzene in strong base: probes for amyloid plaques in the brain. J Med Chem. 2001 Jul 5;44(14):2270-5.

Deacon RM, Raley JM, Perry VH, Rawlins JN. Burrowing into prion disease. Neuroreport. 2001 Jul 3;12(9):2053-7.

Lowe TL, Strzelec A, Kiessling LL, Murphy RM. Structure-function relationships for inhibitors of beta-amyloid toxicity containing the recognition sequence KLVFF. Biochemistry. 2001 Jul 3;40(26):7882-9.

Götz J, Nitsch RM. Compartmentalized tau hyperphosphorylation and increased levels of kinases in transgenic mice. Neuroreport. 2001 Jul 3;12(9):2007-16.

Hosoda T, Nakajima H, Honjo H. Estrogen protects neuronal cells from amyloid beta-induced apoptotic cell death. Neuroreport. 2001 Jul 3;12(9):1965-70.

Grégoire C, Marco S, Thimonier J, Duplan L, Laurine E, Chauvin JP, Michel B, Peyrot V, Verdier JM. Three-dimensional structure of the lithostathine protofibril, a protein involved in Alzheimer's disease. EMBO J. 2001 Jul 2;20(13):3313-21.

Ho PI, Collins SC, Dhitavat S, Ortiz D, Ashline D, Rogers E, Shea TB. Homocysteine potentiates beta-amyloid neurotoxicity: role of oxidative stress. J Neurochem. 2001 Jul;78(2):249-53.

Cedazo-Mínguez A, Cowburn RF. Apolipoprotein E: a major piece in the Alzheimer's disease puzzle. J Cell Mol Med. 2001 Jul-Sep;5(3):254-66.

 

Camps P, Muñoz-Torrero D. Tacrine-huperzine A hybrids (huprines): a new class of highly potent and selective acetylcholinesterase inhibitors of interest for the treatment of Alzheimer's disease. Mini Rev Med Chem. 2001 Jul;1(2):163-74.

McCurry SM, Gibbons LE, Uomoto JM, Thompson ML, Graves AB, Edland SD, Bowen J, McCormick WC, Larson EB. Neuropsychological test performance in a cognitively intact sample of older Japanese American adults(1). Arch Clin Neuropsychol. 2001 Jul;16(5):447-59.

Talaga P. Beta-amyloid aggregation inhibitors for the treatment of Alzheimer's disease: dream or reality? Mini Rev Med Chem. 2001 Jul;1(2):175-86.

Takeuchi M, Makita Z. Alternative routes for the formation of immunochemically distinct advanced glycation end-products in vivo. Curr Mol Med. 2001 Jul;1(3):305-15.

Allen JW, Eldadah BA, Huang X, Knoblach SM, Faden AI. Multiple caspases are involved in beta-amyloid-induced neuronal apoptosis. J Neurosci Res. 2001 Jul 1;65(1):45-53.

Pappolla MA, Omar RA, Chyan YJ, Ghiso J, Hsiao K, Bozner P, Perry G, Smith MA, Cruz-Sanchez F. Induction of NADPH cytochrome P450 reductase by the Alzheimer beta-protein. Amyloid as a "foreign body". J Neurochem. 2001 Jul;78(1):121-8.

Bach JH, Chae HS, Rah JC, Lee MW, Park CH, Choi SH, Choi JK, Lee SH, Kim YS, Kim KY, Lee WB, Suh YH, Kim SS. C-terminal fragment of amyloid precursor protein induces astrocytosis. J Neurochem. 2001 Jul;78(1):109-20.

Matsushita S, Arai H, Yuzuriha T, Kato M, Matsui T, Urakami K, Higuchi S. No association between DLST gene and Alzheimer's disease or Wernicke-Korsakoff syndrome. Neurobiol Aging. 2001 Jul-Aug;22(4):569-74. ,

Ertekin-Taner N, Graff-Radford N, Younkin LH, Eckman C, Adamson J, Schaid DJ, Blangero J, Hutton M, Younkin SG. Heritability of plasma amyloid beta in typical late-onset Alzheimer's disease pedigrees. Genet Epidemiol. 2001 Jul;21(1):19-30. ,

Zubenko GS, Hughes HB, Stiffler JS. D10S1423 identifies a susceptibility locus for Alzheimer's disease in a prospective, longitudinal, double-blind study of asymptomatic individuals. Mol Psychiatry. 2001 Jul;6(4):413-9.

 

Lue LF, Rydel R, Brigham EF, Yang LB, Hampel H, Murphy GM, Brachova L, Yan SD, Walker DG, Shen Y, Rogers J. Inflammatory repertoire of Alzheimer's disease and nondemented elderly microglia in vitro. Glia. 2001 Jul;35(1):72-9.

Götz J. Tau and transgenic animal models. Brain Res Brain Res Rev. 2001 Jul;35(3):266-86.

Qiu Z, Naten DL, Liston JC, Yess J, Rebeck GW. A novel approach for studying endogenous abeta processing using cultured primary neurons isolated from APP transgenic mice. Exp Neurol. 2001 Jul;170(1):186-94.

Trippi F, Botto N, Scarpato R, Petrozzi L, Bonuccelli U, Latorraca S, Sorbi S, Migliore L. Spontaneous and induced chromosome damage in somatic cells of sporadic and familial Alzheimer's disease patients. Mutagenesis. 2001 Jul;16(4):323-7.

Emahazion T, Feuk L, Jobs M, Sawyer SL, Fredman D, St Clair D, Prince JA, Brookes AJ. SNP association studies in Alzheimer's disease highlight problems for complex disease analysis. Trends Genet. 2001 Jul;17(7):407-13. ,

 

Tschampa HJ, Neumann M, Zerr I, Henkel K, Schröter A, Schulz-Schaeffer WJ, Steinhoff BJ, Kretzschmar HA, Poser S. Patients with Alzheimer's disease and dementia with Lewy bodies mistaken for Creutzfeldt-Jakob disease. J Neurol Neurosurg Psychiatry. 2001 Jul;71(1):33-9.

MacDonald MC, Almor A, Henderson VW, Kempler D, Andersen ES. Assessing working memory and language comprehension in Alzheimer's disease. Brain Lang. 2001 Jul;78(1):17-42.

Blansjaar BA, van Schaick HW. Advising relatives of risk of Alzheimer's disease. Br J Psychiatry. 2001 Jul;179:73-4.

Fitzjohn SM, Morton RA, Kuenzi F, Rosahl TW, Shearman M, Lewis H, Smith D, Reynolds DS, Davies CH, Collingridge GL, Seabrook GR. Age-related impairment of synaptic transmission but normal long-term potentiation in transgenic mice that overexpress the human APP695SWE mutant form of amyloid precursor protein. J Neurosci. 2001 Jul 1;21(13):4691-8.

Habeck M. Is Alzheimer's disease a form of cancer? Drug Discov Today. 2001 Jul 1;6(13):651-652.

Hynd MR, Scott HL, Dodd PR. Glutamate(NMDA) receptor NR1 subunit mRNA expression in Alzheimer's disease. J Neurochem. 2001 Jul;78(1):175-82.

Rüb U, Del Tredici K, Schultz C, Büttner-Ennever JA, Braak H. The premotor region essential for rapid vertical eye movements shows early involvement in Alzheimer's disease-related cytoskeletal pathology. Vision Res. 2001 Jul;41(16):2149-56.

Dupuy AM, Mas E, Ritchie K, Descomps B, Badiou S, Cristol JP, Touchon J. The relationship between apolipoprotein E4 and lipid metabolism is impaired in Alzheimer's disease. Gerontology. 2001 Jul-Aug;47(4):213-8.

Klegeris A, Schwab C, Bissonnette CJ, McGeer PL. Induction of complement C9 messenger RNAs in human neuronal cells by inflammatory stimuli: relevance to neurodegenerative disorders. Exp Gerontol. 2001 Jul;36(7):1179-88.

Debanne SM, Petot GJ, Li J, Koss E, Lerner AJ, Riedel TM, Rowland DY, Smyth KA, Friedland RP. On the use of surrogate respondents for controls in a case-control study of Alzheimer's disease. J Am Geriatr Soc. 2001 Jul;49(7):980-4.

Kawakami H. [Molecular biology of glutamate transporters in Alzheimer's disease] Nippon Ronen Igakkai Zasshi. 2001 Jul;38(4):489-90.

Tractenberg RE, Schafer K, Morris JC. Interobserver disagreements on clinical dementia rating assessment: interpretation and implications for training. Alzheimer Dis Assoc Disord. 2001 Jul-Sep;15(3):155-61.

Rideout HJ, Stefanis L. Caspase inhibition: a potential therapeutic strategy in neurological diseases. Histol Histopathol. 2001 Jul;16(3):895-908.

Boeve BF, Silber MH, Ferman TJ, Lucas JA, Parisi JE. Association of REM sleep behavior disorder and neurodegenerative disease may reflect an underlying synucleinopathy. Mov Disord. 2001 Jul;16(4):622-30.

Yamaguchi H, Tamura R, Kuriwaki JI, Eifuku S, Ono T. Effects of T-588, a cognitive enhancer compound, on synaptic plasticity in the dentate gyrus of freely moving rats. J Pharmacol Exp Ther. 2001 Jul;298(1):354-61.

Papagno C. Comprehension of metaphors and idioms in patients with Alzheimer's disease: a longitudinal study. Brain. 2001 Jul;124(Pt 7):1450-60.

Valla J, Berndt JD, Gonzalez-Lima F. Energy hypometabolism in posterior cingulate cortex of Alzheimer's patients: superficial laminar cytochrome oxidase associated with disease duration. J Neurosci. 2001 Jul 1;21(13):4923-30.

Kopelman MD, Lasserson D, Kingsley D, Bello F, Rush C, Stanhope N, Stevens T, Goodman G, Heilpern G, Kendall B, Colchester A. Structural MRI volumetric analysis in patients with organic amnesia, 2: correlations with anterograde memory and executive tests in 40 patients. J Neurol Neurosurg Psychiatry. 2001 Jul;71(1):23-8.

Price JM, Chi X, Hellermann G, Sutton ET. Physiological levels of beta-amyloid induce cerebral vessel dysfunction and reduce endothelial nitric oxide production. Neurol Res. 2001 Jul;23(5):506-12.

Kim H, Kim S, Go H, Kim D. Synergetic analysis of spatio-temporal EEG patterns: Alzheimer's disease. Biol Cybern. 2001 Jul;85(1):1-17.

García-Sierra F, Wischik CM, Harrington CR, Luna-Muñoz J, Mena R. Accumulation of C-terminally truncated tau protein associated with vulnerability of the perforant pathway in early stages of neurofibrillary pathology in Alzheimer's disease. J Chem Neuroanat. 2001 Jul;22(1-2):65-77.

 

Leroy K, Duyckaerts C, Bovekamp L, Müller O, Anderton BH, Brion JP. Increase of adenomatous polyposis coli immunoreactivity is a marker of reactive astrocytes in Alzheimer's disease and in other pathological conditions. Acta Neuropathol (Berl). 2001 Jul;102(1):1-10.

De Groot CJ, Hulshof S, Hoozemans JJ, Veerhuis R. Establishment of microglial cell cultures derived from postmortem human adult brain tissue: immunophenotypical and functional characterization. Microsc Res Tech. 2001 Jul 1;54(1):34-9.

Isbir T, Agaçhan B, Yilmaz H, Aydin M, Kara I, Eker D, Eker E. Interaction between apolipoprotein-E and angiotensin-converting enzyme genotype in Alzheimer's disease. Am J Alzheimers Dis Other Demen. 2001 Jul-Aug;16(4):205-10. ,

Li YS, Meyer JS, Thornby J. Longitudinal follow-up of depressive symptoms among normal versus cognitively impaired elderly. Int J Geriatr Psychiatry. 2001 Jul;16(7):718-27.

Waite LM, Broe GA, Grayson DA, Creasey H. The incidence of dementia in an Australian community population: the Sydney Older Persons Study. Int J Geriatr Psychiatry. 2001 Jul;16(7):680-9.

Fabrizi C, Businaro R, Lauro GM, Fumagalli L. Role of alpha2-macroglobulin in regulating amyloid beta-protein neurotoxicity: protective or detrimental factor? J Neurochem. 2001 Jul;78(2):406-12.

Bodles AM, Guthrie DJ, Greer B, Irvine GB. Identification of the region of non-Abeta component (NAC) of Alzheimer's disease amyloid responsible for its aggregation and toxicity. J Neurochem. 2001 Jul;78(2):384-95.

Albert MS, Moss MB, Tanzi R, Jones K. Preclinical prediction of AD using neuropsychological tests. J Int Neuropsychol Soc. 2001 Jul;7(5):631-9.

Goethals M, Santens P. Posterior cortical atrophy. Two case reports and a review of the literature. Clin Neurol Neurosurg. 2001 Jul;103(2):115-9.

Cherrier MM, Mendez M, Perryman K. Route learning performance in Alzheimer disease patients. Neuropsychiatry Neuropsychol Behav Neurol. 2001 Jul-Sep;14(3):159-68.

Cuerva AG, Sabe L, Kuzis G, Tiberti C, Dorrego F, Starkstein SE. Theory of mind and pragmatic abilities in dementia. Neuropsychiatry Neuropsychol Behav Neurol. 2001 Jul-Sep;14(3):153-8.

Rehman HU, Masson EA. Neuroendocrinology of ageing. Age Ageing. 2001 Jul;30(4):279-87.

Braginskaya FI, Zorina M, Pal'mina NP, Gaintseva VD, Burlakova EB, Selezneva ND, Kolykhalov IV, Gavrilova SI. Some blood biochemistry parameters during the cholinergic treatment of Alzheimer's disease. Neurosci Behav Physiol. 2001 Jul-Aug;31(4):457-61.

Calabrese EJ. Amyloid beta-peptide: biphasic dose responses. Crit Rev Toxicol. 2001 Jul;31(4-5):605-6.

Meehan RA, Brush JA. An overview of AIDS dementia complex. Am J Alzheimers Dis Other Demen. 2001 Jul-Aug;16(4):225-9.

Fung TD, Chertkow H, Murtha S, Whatmough C, Péloquin L, Whitehead V, Templeman FD. The spectrum of category effects in object and action knowledge in dementia of the Alzheimer's type. Neuropsychology. 2001 Jul;15(3):371-9.

Kim DK, Seo MY, Lim SW, Kim S, Kim JW, Carroll BJ, Kwon DY, Kwon T, Kang SS. Serum melanotransferrin, p97 as a biochemical marker of Alzheimer's disease. Neuropsychopharmacology. 2001 Jul;25(1):84-90. ,

Doody RS, Dunn JK, Clark CM, Farlow M, Foster NL, Liao T, Gonzales N, Lai E, Massman P. Chronic donepezil treatment is associated with slowed cognitive decline in Alzheimer's disease. Dement Geriatr Cogn Disord. 2001 Jul-Aug;12(4):295-300.

Smith MZ, Esiri MM, Barnetson L, King E, Nagy Z. Constructional apraxia in Alzheimer's disease: association with occipital lobe pathology and accelerated cognitive decline. Dement Geriatr Cogn Disord. 2001 Jul-Aug;12(4):281-8.

Swainson R, Hodges JR, Galton CJ, Semple J, Michael A, Dunn BD, Iddon JL, Robbins TW, Sahakian BJ. Early detection and differential diagnosis of Alzheimer's disease and depression with neuropsychological tasks. Dement Geriatr Cogn Disord. 2001 Jul-Aug;12(4):265-80.

 

Sjögren M, Davidsson P, Gottfries J, Vanderstichele H, Edman A, Vanmechelen E, Wallin A, Blennow K. The cerebrospinal fluid levels of tau, growth-associated protein-43 and soluble amyloid precursor protein correlate in Alzheimer's disease, reflecting a common pathophysiological process. Dement Geriatr Cogn Disord. 2001 Jul-Aug;12(4):257-64. ,

Stewart R, Russ C, Richards M, Brayne C, Lovestone S, Mann A. Apolipoprotein E genotype, vascular risk and early cognitive impairment in an African Caribbean population. Dement Geriatr Cogn Disord. 2001 Jul-Aug;12(4):251-6.

Davidsson P, Bogdanovic N, Lannfelt L, Blennow K. Reduced expression of amyloid precursor protein, presenilin-1 and rab3a in cortical brain regions in Alzheimer's disease. Dement Geriatr Cogn Disord. 2001 Jul-Aug;12(4):243-50. ,

Tooyama I, Sato H, Yasuhara O, Kimura H, Konishi Y, Shen Y, Walker DG, Beach TG, Sue LI, Rogers J. Correlation of the expression level of C1q mRNA and the number of C1q-positive plaques in the Alzheimer Disease temporal cortex. analysis of C1q mrna and its protein using adjacent or nearby sections. Dement Geriatr Cogn Disord. 2001 Jul-Aug;12(4):237-42.

Wiesinger H. Arginine metabolism and the synthesis of nitric oxide in the nervous system. Prog Neurobiol. 2001 Jul;64(4):365-91.

Slawek J, Bojko E, Szady J. [Incidence of dementia in Parkinson disease] Neurol Neurochir Pol. 2001 Jul-Aug;35(4):569-81.

Olson RE, Copeland RA, Seiffert D. Progress towards testing the amyloid hypothesis: inhibitors of APP processing. Curr Opin Drug Discov Devel. 2001 Jul;4(4):390-401.

Van Nostrand WE, Melchor JP. Disruption of pathologic amyloid beta-protein fibril assembly on the surface of cultured human cerebrovascular smooth muscle cells. Amyloid. 2001 Jul;8 Suppl 1:20-7.

Yang DS, Serpell LC, Yip CM, McLaurin J, Chrishti MA, Horne P, Boudreau L, Kisilevsky R, Westaway D, Fraser PE. Assembly of Alzheimer's amyloid-beta fibrils and approaches for therapeutic intervention. Amyloid. 2001 Jul;8 Suppl 1:10-9.

Christie R, Kimchi E, Kajdasz S, Bacskai B, Hyman BT. Multiphoton microscopy and amyloid angiopathy. Amyloid. 2001 Jul;8 Suppl 1:48-50.

Palotás A, Kálmán J, Laskay G, Juhász A, Janka Z, Penke B. Comparative studies on [Ca2+]i-level of fibroblasts from Alzheimer patients and control individuals. Neurochem Res. 2001 Jul;26(7):817-20.

Pettegrew JW, Panchalingam K, Hamilton RL, McClure RJ. Brain membrane phospholipid alterations in Alzheimer's disease. Neurochem Res. 2001 Jul;26(7):771-82.

Bieber EJ, Cohen DP. Estrogens and hormone replacement therapy: is there a role in the preservation of cognitive function? Int J Fertil Womens Med. 2001 Jul-Aug;46(4):206-9.

Nicoll JA, McCarron MO. APOE gene polymorphism as a risk factor for cerebral amyloid angiopathy-related hemorrhage. Amyloid. 2001 Jul;8 Suppl 1:51-5.

Frangione B, Révész T, Vidal R, Holton J, Lashley T, Houlden H, Wood N, Rostagno A, Plant G, Ghiso J. Familial cerebral amyloid angiopathy related to stroke and dementia. Amyloid. 2001 Jul;8 Suppl 1:36-42.

Zablocka A, Janusz M, Rybka K, Wirkus-Romanowska I, Kupryszewski G, Lisowski J. Cytokine-inducing activity of a proline-rich polypeptide complex (PRP) from ovine colostrum and its active nonapeptide fragment analogs. Eur Cytokine Netw. 2001 Jul-Sep;12(3):462-7.

Vincent B, Smith JD. Astrocytes down-regulate neuronal beta-amyloid precursor protein expression and modify its processing in an apolipoprotein E isoform-specific manner. Eur J Neurosci. 2001 Jul;14(2):256-66.

Bartrés-Faz D, Junqué C, López-Alomar A, Valveny N, Moral P, Casamayor R, Salido A, Bel C, Clemente IC. Neuropsychological and genetic differences between age-associated memory impairment and mild cognitive impairment entities. J Am Geriatr Soc. 2001 Jul;49(7):985-90.

Paganini-Hill A, Clark LJ, Henderson VW, Birge SJ. Clock drawing: analysis in a retirement community. J Am Geriatr Soc. 2001 Jul;49(7):941-7.

Berco M, Bhavnani BR. Differential neuroprotective effects of equine estrogens against oxidized low density lipoprotein-induced neuronal cell death. J Soc Gynecol Investig. 2001 Jul-Aug;8(4):245-54.

Hass S, Weidemann A, Utermann G, Baier G. Intracellular apolipoprotein E affects Amyloid Precursor Protein processing and amyloid Abeta production in COS-1 cells. Mol Genet Genomics. 2001 Jul;265(5):791-800.

Pirskanen M, Alafuzoff I, Hiltunen M, Mannermaa A, Helisalmi S, Lehtovirta M, Koivisto AM, Laakso M, Soininen H. An association between a subset of Finnish late-onset Alzheimer's disease and alpha2-macroglobulin. Neurogenetics. 2001 Jul;3(3):171-2.

Yanagisawa K. [Molecular mechanism underlying the development of Alzheimer's disease: implications of apolipoprotein E and presenilin] Nippon Ronen Igakkai Zasshi. 2001 Jul;38(4):455-7.

Knopman D, Patterson M. An open-label, 24-week pilot study of the methyl donor betaine in Alzheimer disease patients. Alzheimer Dis Assoc Disord. 2001 Jul-Sep;15(3):162-5.

Pucci E, Belardinelli N, Borsetti G, Rodriguez D, Signorino M. Information and competency for consent to pharmacologic clinical trials in Alzheimer disease: an empirical analysis in patients and family caregivers. Alzheimer Dis Assoc Disord. 2001 Jul-Sep;15(3):146-54.

Connell CM, Shaw BA, Holmes SB, Foster NL. Caregivers' attitudes toward their family members' participation in Alzheimer disease research: implications for recruitment and retention. Alzheimer Dis Assoc Disord. 2001 Jul-Sep;15(3):137-45.

Hamdy RC. Alzheimer's disease: an overview. South Med J. 2001 Jul;94(7):661-2.

Gebicke-Haerter PJ. Microglia in neurodegeneration: molecular aspects. Microsc Res Tech. 2001 Jul 1;54(1):47-58.

Frisoni GB. Treatment of Alzheimer's disease with acetylcholinesterase inhibitors: bridging the gap between evidence and practice. J Neurol. 2001 Jul;248(7):551-7.

Lee SS. Effective screening for Alzheimer's disease in everyday practice. JAAPA. 2001 Jul;14(7):39-48.

MacLeod MJ, De Lange RP, Breen G, Meiklejohn D, Lemmon H, Clair DS. Lack of association between apolipoprotein E genoype and ischaemic stroke in a Scottish population. Eur J Clin Invest. 2001 Jul;31(7):570-3.

Carrell RW, Huntington JA, Mushunje A, Zhou A. The conformational basis of thrombosis. Thromb Haemost. 2001 Jul;86(1):14-22.

Londos E, Passant U, Gustafson L, Brun A. Neuropathological correlates to clinically defined dementia with Lewy bodies. Int J Geriatr Psychiatry. 2001 Jul;16(7):667-79.

Ott MO, Bullock SL. A gene trap insertion reveals that amyloid precursor protein expression is a very early event in murine embryogenesis. Dev Genes Evol. 2001 Jul;211(7):355-7.

 

Justino L, Kergoat M, Bergman H, Chertkow H, Robillard A, Kergoat H. Neuroretinal function is normal in early dementia of the Alzheimer type. Neurobiol Aging. 2001 Jul-Aug;22(4):691-5.

Ruitenberg A, Ott A, van Swieten JC, Hofman A, Breteler MM. Incidence of dementia: does gender make a difference? Neurobiol Aging. 2001 Jul-Aug;22(4):575-80.

Sampietro M, Caputo L, Casatta A, Meregalli M, Pellagatti A, Tagliabue J, Annoni G, Vergani C. The hemochromatosis gene affects the age of onset of sporadic Alzheimer's disease. Neurobiol Aging. 2001 Jul-Aug;22(4):563-8. ,

Leverenz JB, Miller MA, Dobie DJ, Peskind ER, Raskind MA. Increased alpha 2-adrenergic receptor binding in locus coeruleus projection areas in dementia with Lewy bodies. Neurobiol Aging. 2001 Jul-Aug;22(4):555-61.

Savaskan E, Hock C, Olivieri G, Bruttel S, Rosenberg C, Hulette C, Müller-Spahn F. Cortical alterations of angiotensin converting enzyme, angiotensin II and AT1 receptor in Alzheimer's dementia. Neurobiol Aging. 2001 Jul-Aug;22(4):541-6.

Dranovsky A, Vincent I, Gregori L, Schwarzman A, Colflesh D, Enghild J, Strittmatter W, Davies P, Goldgaber D. Cdc2 phosphorylation of nucleolin demarcates mitotic stages and Alzheimer's disease pathology. Neurobiol Aging. 2001 Jul-Aug;22(4):517-28.

Hake AM. Use of cholinesterase inhibitors for treatment of Alzheimer disease. Cleve Clin J Med. 2001 Jul;68(7):608-9, 613-4, 616.

Cummings CJ, Sun Y, Opal P, Antalffy B, Mestril R, Orr HT, Dillmann WH, Zoghbi HY. Over-expression of inducible HSP70 chaperone suppresses neuropathology and improves motor function in SCA1 mice. Hum Mol Genet. 2001 Jul 1;10(14):1511-8.

Yamaguchi H, Sugihara S, Ogawa A, Oshima N, Ihara Y. Alzheimer beta amyloid deposition enhanced by apoE epsilon4 gene precedes neurofibrillary pathology in the frontal association cortex of nondemented senior subjects. J Neuropathol Exp Neurol. 2001 Jul;60(7):731-9.

Picklo MJ, Olson SJ, Markesbery WR, Montine TJ. Expression and activities of aldo-keto oxidoreductases in Alzheimer disease. J Neuropathol Exp Neurol. 2001 Jul;60(7):686-95.

Winblad B, Brodaty H, Gauthier S, Morris JC, Orgogozo JM, Rockwood K, Schneider L, Takeda M, Tariot P, Wilkinson D. Pharmacotherapy of Alzheimer's disease: is there a need to redefine treatment success? Int J Geriatr Psychiatry. 2001 Jul 1;16(7):653-66.

Lauderback CM, Hackett JM, Huang FF, Keller JN, Szweda LI, Markesbery WR, Butterfield DA. The glial glutamate transporter, GLT-1, is oxidatively modified by 4-hydroxy-2-nonenal in the Alzheimer's disease brain: the role of Abeta1-42. J Neurochem. 2001 Jul;78(2):413-6.

 

Bajetto A, Bonavia R, Barbero S, Florio T, Schettini G. Chemokines and their receptors in the central nervous system. Front Neuroendocrinol. 2001 Jul;22(3):147-84.

Choi MH, Kim KR, Kim IS, Lho DS, Chung BC. Increased hair polyamine levels in patients with Alzheimer's disease. Ann Neurol. 2001 Jul;50(1):128.

2001: January: Alzheimer’s Research Papers

2001: January: Alzheimer’s Research Papers    

Sharma M, Gupta YK. Intracerebroventricular injection of streptozotocin in rats produces both oxidative stress in the brain and cognitive impairment. Life Sci. 2001 Jan 19;68(9):1021-9.

Hesse C, Rosengren L, Andreasen N, Davidsson P, Vanderstichele H, Vanmechelen E, Blennow K. Transient increase in total tau but not phospho-tau in human cerebrospinal fluid after acute stroke. Neurosci Lett. 2001 Jan 19;297(3):187-90.

Richard F, Amouyel P. Genetic susceptibility factors for Alzheimer's disease. Eur J Pharmacol. 2001 Jan 19;412(1):1-12.

Yao Z, Drieu K, Papadopoulos V. The Ginkgo biloba extract EGb 761 rescues the PC12 neuronal cells from beta-amyloid-induced cell death by inhibiting the formation of beta-amyloid-derived diffusible neurotoxic ligands. Brain Res. 2001 Jan 19;889(1-2):181-90.

Sato N, Imaizumi K, Manabe T, Taniguchi M, Hitomi J, Katayama T, Yoneda T, Morihara T, Yasuda Y, Takagi T, Kudo T, Tsuda T, Itoyama Y, Makifuchi T, Fraser PE, St George-Hyslop P, Tohyama M. Increased production of beta-amyloid and vulnerability to endoplasmic reticulum stress by an aberrant spliced form of presenilin 2. J Biol Chem. 2001 Jan 19;276(3):2108-14.

Sáez-Valero J, Small DH. Altered glycosylation of cerebrospinal fluid butyrylcholinesterase in Alzheimer's disease. Brain Res. 2001 Jan 19;889(1-2):247-50. ,

Dahlin M, Björk E. Nasal administration of a physostigmine analogue (NXX-066) for Alzheimer's disease to rats. Int J Pharm. 2001 Jan 16;212(2):267-74.

O'Brien J, Thomas A, Ballard C, Brown A, Ferrier N, Jaros E, Perry R. Cognitive impairment in depression is not associated with neuropathologic evidence of increased vascular or Alzheimer-type pathology. Biol Psychiatry. 2001 Jan 15;49(2):130-6.

Lucas JJ, Hernández F, Gómez-Ramos P, Morán MA, Hen R, Avila J. Decreased nuclear beta-catenin, tau hyperphosphorylation and neurodegeneration in GSK-3beta conditional transgenic mice. EMBO J. 2001 Jan 15;20(1-2):27-39.

 

Baskin F, Rosenberg RN, Iyer L, Schellenberg GD, Hynan L, Nee LE. Platelet APP isoform ratios in asymptomatic young adults expressing an AD-related presenilin-1 mutation. J Neurol Sci. 2001 Jan 15;183(1):85-8.

Le Y, Gong W, Tiffany HL, Tumanov A, Nedospasov S, Shen W, Dunlop NM, Gao JL, Murphy PM, Oppenheim JJ, Wang JM. Amyloid (beta)42 activates a G-protein-coupled chemoattractant receptor, FPR-like-1. J Neurosci. 2001 Jan 15;21(2):RC123.

Kawarabayashi T, Younkin LH, Saido TC, Shoji M, Ashe KH, Younkin SG. Age-dependent changes in brain, CSF, and plasma amyloid (beta) protein in the Tg2576 transgenic mouse model of Alzheimer's disease. J Neurosci. 2001 Jan 15;21(2):372-81. ,

 

Nash JM. Alzheimer's disease. New insights into its cause lead to new drug strategies. Time. 2001 Jan 15;157(2):80-1, 85.

Hebert LE, Scherr PA, McCann JJ, Beckett LA, Evans DA. Is the risk of developing Alzheimer's disease greater for women than for men? Am J Epidemiol. 2001 Jan 15;153(2):132-6.

 

Arai Y, Yamazaki M, Mori O, Muramatsu H, Asano G, Katayama Y. Alpha-synuclein-positive structures in cases with sporadic Alzheimer's disease: morphology and its relationship to tau aggregation. Brain Res. 2001 Jan 12;888(2):287-296. ,

 

Sasaki N, Toki S, Chowei H, Saito T, Nakano N, Hayashi Y, Takeuchi M, Makita Z. Immunohistochemical distribution of the receptor for advanced glycation end products in neurons and astrocytes in Alzheimer's disease. Brain Res. 2001 Jan 12;888(2):256-262.

 

Guo GW, Liang YX. Aluminum-induced apoptosis in cultured astrocytes and its effect on calcium homeostasis. Brain Res. 2001 Jan 12;888(2):221-226.

Yoo BC, Kim SH, Cairns N, Fountoulakis M, Lubec G. Deranged expression of molecular chaperones in brains of patients with Alzheimer's disease. Biochem Biophys Res Commun. 2001 Jan 12;280(1):249-58.

Hino H, Akiyama H, Iseki E, Kato M, Kondo H, Ikeda K, Kosaka K. Immunohistochemical localization of plasminogen activator inhibitor-1 in rat and human brain tissues. Neurosci Lett. 2001 Jan 12;297(2):105-8.

Yasojima K, Akiyama H, McGeer EG, McGeer PL. Reduced neprilysin in high plaque areas of Alzheimer brain: a possible relationship to deficient degradation of beta-amyloid peptide. Neurosci Lett. 2001 Jan 12;297(2):97-100. ,

    

von Arnim CA, Ludolph AC. [Normal and pathological aging of the brain] Fortschr Med Orig. 2001 Jan 11;118(4):165-8.

Burneo JG, Papamitsakis NI, Mitsias PD. Cerebral ventricles are smaller in Hispanic than non-Hispanic patients with Alzheimer's disease. Neurology. 2001 Jan 9;56(1):139-40.

Masliah E, Mallory M, Alford M, DeTeresa R, Hansen LA, McKeel DW, Morris JC. Altered expression of synaptic proteins occurs early during progression of Alzheimer's disease. Neurology. 2001 Jan 9;56(1):127-9. ,

Sánchez L, Alvarez V, González P, González I, Alvarez R, Coto E. Variation in the LRP-associated protein gene (LRPAP1) is associated with late-onset Alzheimer disease. Am J Med Genet. 2001 Jan 8;105(1):76-8. ,

Hyde LA, Frisone DF, Crnic LS. Ts65Dn mice, a model for Down syndrome, have deficits in context discrimination learning suggesting impaired hippocampal function. Behav Brain Res. 2001 Jan 8;118(1):53-60.

Berger A. Vaccine improves memory in "Alzheimer's" mice. BMJ. 2001 Jan 6;322(7277):9.

Leclerc S, Garnier M, Hoessel R, Marko D, Bibb JA, Snyder GL, Greengard P, Biernat J, Wu YZ, Mandelkow EM, Eisenbrand G, Meijer L. Indirubins inhibit glycogen synthase kinase-3 beta and CDK5/p25, two protein kinases involved in abnormal tau phosphorylation in Alzheimer's disease. A property common to most cyclin-dependent kinase inhibitors? J Biol Chem. 2001 Jan 5;276(1):251-60.

Kim D, Koh WK, Kim JU, Lee JH, Hong HN. Okadaic acid-induced upregulation of nitrotyrosine and heme oxygenase-1 in rat cortical neuron cultures. Neurosci Lett. 2001 Jan 5;297(1):33-6.

Yoshida T, Tanaka M, Okamoto K. Inhibitory effect of nicergoline on superoxide generation by activated rat microglias measured using a simple chemiluminescence method. Neurosci Lett. 2001 Jan 5;297(1):5-8.

Forloni G, Colombo L, Girola L, Tagliavini F, Salmona M. Anti-amyloidogenic activity of tetracyclines: studies in vitro. FEBS Lett. 2001 Jan 5;487(3):404-7.

 

Pinnix I, Musunuru U, Tun H, Sridharan A, Golde T, Eckman C, Ziani-Cherif C, Onstead L, Sambamurti K. A novel gamma -secretase assay based on detection of the putative C-terminal fragment-gamma of amyloid beta protein precursor. J Biol Chem. 2001 Jan 5;276(1):481-7.

Struhl G, Greenwald I. Presenilin-mediated transmembrane cleavage is required for Notch signal transduction in Drosophila. Proc Natl Acad Sci U S A. 2001 Jan 2;98(1):229-34.

Bäckman L, Small BJ, Fratiglioni L. Stability of the preclinical episodic memory deficit in Alzheimer's disease. Brain. 2001 Jan;124(Pt 1):96-102.

Chorsky RL, Yaghmai F, Hill WD, Stopa EG. Alzheimer's disease: a review concerning immune response and microischemia. Med Hypotheses. 2001 Jan;56(1):124-7.

Jones GR. Causes of Alzheimer's disease: paracetamol (acetaminophen) today? Amphetamines tomorrow? Med Hypotheses. 2001 Jan;56(1):121-3.

Neill D, Hughes D, Leake A, Morris C, Jones D, Oakley A, Edwardson J, Estibeiro P. Neuritogenic-neurotoxic effects of membrane-associated forms of amyloid precursor protein. Dement Geriatr Cogn Disord. 2001 Jan-Feb;12(1):40-51.

Almkvist O, Jelic V, Amberla K, Hellström-Lindahl E, Meurling L, Nordberg A. Responder characteristics to a single oral dose of cholinesterase inhibitor: a double-blind placebo-controlled study with tacrine in Alzheimer patients. Dement Geriatr Cogn Disord. 2001 Jan-Feb;12(1):22-32.

Hirono N, Mori E, Ishii K, Imamura T, Tanimukai S, Kazui H, Hashimoto M, Takatsuki Y, Kitagaki H, Sasaki M. Neuronal substrates for semantic memory: a positron emission tomography study in Alzheimer's disease. Dement Geriatr Cogn Disord. 2001 Jan-Feb;12(1):15-21.

Chemerinski E, Petracca G, Sabe L, Kremer J, Starkstein SE. The specificity of depressive symptoms in patients with Alzheimer's disease. Am J Psychiatry. 2001 Jan;158(1):68-72.

Shaji KS, Kishore NR, Praveenlal K. Information and education for carers of patients with Alzheimer's disease. Br J Psychiatry. 2001 Jan;178(1):83-4.

Liddell MB, Lovestone S, Owen MJ. Genetic risk of Alzheimer's disease: advising relatives. Br J Psychiatry. 2001 Jan;178(1):7-11.

Chodobski A, Szmydynger-Chodobska J. Choroid plexus: target for polypeptides and site of their synthesis. Microsc Res Tech. 2001 Jan 1;52(1):65-82.

Rypniewski WR, Ostergaard PR, Nørregaard-Madsen M, Dauter M, Wilson KS. Fusarium oxysporum trypsin at atomic resolution at 100 and 283 K: a study of ligand binding. Acta Crystallogr D Biol Crystallogr. 2001 Jan;57(Pt 1):8-19.

Kontush A, Berndt C, Weber W, Akopyan V, Arlt S, Schippling S, Beisiegel U. Amyloid-beta is an antioxidant for lipoproteins in cerebrospinal fluid and plasma. Free Radic Biol Med. 2001 Jan 1;30(1):119-28.

Fallin D, Cohen A, Essioux L, Chumakov I, Blumenfeld M, Cohen D, Schork NJ. Genetic analysis of case/control data using estimated haplotype frequencies: application to APOE locus variation and Alzheimer's disease. Genome Res. 2001 Jan;11(1):143-51.

Touchman JW, Dehejia A, Chiba-Falek O, Cabin DE, Schwartz JR, Orrison BM, Polymeropoulos MH, Nussbaum RL. Human and mouse alpha-synuclein genes: comparative genomic sequence analysis and identification of a novel gene regulatory element. Genome Res. 2001 Jan;11(1):78-86.

Pettit DL, Shao Z, Yakel JL. beta-Amyloid(1-42) peptide directly modulates nicotinic receptors in the rat hippocampal slice. J Neurosci. 2001 Jan 1;21(1):RC120.

Xu J, Chen S, Ahmed SH, Chen H, Ku G, Goldberg MP, Hsu CY. Amyloid-beta peptides are cytotoxic to oligodendrocytes. J Neurosci. 2001 Jan 1;21(1):RC118.

Pruessner JC, Collins DL, Pruessner M, Evans AC. Age and gender predict volume decline in the anterior and posterior hippocampus in early adulthood. J Neurosci. 2001 Jan 1;21(1):194-200.

Cunnane G. Amyloid precursors and amyloidosis in inflammatory arthritis. Curr Opin Rheumatol. 2001 Jan;13(1):67-73.

Standen CL, Brownlees J, Grierson AJ, Kesavapany S, Lau KF, McLoughlin DM, Miller CC. Phosphorylation of thr(668) in the cytoplasmic domain of the Alzheimer's disease amyloid precursor protein by stress-activated protein kinase 1b (Jun N-terminal kinase-3). J Neurochem. 2001 Jan;76(1):316-20.

Olivieri G, Baysang G, Meier F, Müller-Spahn F, Stähelin HB, Brockhaus M, Brack C. N-acetyl-L-cysteine protects SHSY5Y neuroblastoma cells from oxidative stress and cell cytotoxicity: effects on beta-amyloid secretion and tau phosphorylation. J Neurochem. 2001 Jan;76(1):224-33.

Dovey HF, John V, Anderson JP, Chen LZ, de Saint Andrieu P, Fang LY, Freedman SB, Folmer B, Goldbach E, Holsztynska EJ, Hu KL, Johnson-Wood KL, Kennedy SL, Kholodenko D, Knops JE, Latimer LH, Lee M, Liao Z, Lieberburg IM, Motter RN, Mutter LC, Nietz J, Quinn KP, Sacchi KL, Seubert PA, Shopp GM, Thorsett ED, Tung JS, Wu J, Yang S, Yin CT, Schenk DB, May PC, Altstiel LD, Bender MH, Boggs LN, Britton TC, Clemens JC, Czilli DL, Dieckman-McGinty DK, Droste JJ, Fuson KS, Gitter BD, Hyslop PA, Johnstone EM, Li WY, Little SP, Mabry TE, Miller FD, Audia JE. Functional gamma-secretase inhibitors reduce beta-amyloid peptide levels in brain. J Neurochem. 2001 Jan;76(1):173-81.

 

Drouet B, Fifre A, Pinçon-Raymond M, Vandekerckhove J, Rosseneu M, Guéant JL, Chambaz J, Pillot T. ApoE protects cortical neurones against neurotoxicity induced by the non-fibrillar C-terminal domain of the amyloid-beta peptide. J Neurochem. 2001 Jan;76(1):117-27.

Dubal DB, Wise PM. Neuroprotective effects of estradiol in middle-aged female rats. Endocrinology. 2001 Jan;142(1):43-8.

Bayer TA, Wirths O, Majtényi K, Hartmann T, Multhaup G, Beyreuther K, Czech C. Key factors in Alzheimer's disease: beta-amyloid precursor protein processing, metabolism and intraneuronal transport. Brain Pathol. 2001 Jan;11(1):1-11.

Ebert U, Grossmann M, Oertel R, Gramatté T, Kirch W. Pharmacokinetic-pharmacodynamic modeling of the electroencephalogram effects of scopolamine in healthy volunteers. J Clin Pharmacol. 2001 Jan;41(1):51-60.

Reich EE, Markesbery WR, Roberts LJ, Swift LL, Morrow JD, Montine TJ. Brain regional quantification of F-ring and D-/E-ring isoprostanes and neuroprostanes in Alzheimer's disease. Am J Pathol. 2001 Jan;158(1):293-7.

Hall GF, Lee VM, Lee G, Yao J. Staging of neurofibrillary degeneration caused by human tau overexpression in a unique cellular model of human tauopathy. Am J Pathol. 2001 Jan;158(1):235-46.

 

Rohn TT, Head E, Su JH, Anderson AJ, Bahr BA, Cotman CW, Cribbs DH. Correlation between caspase activation and neurofibrillary tangle formation in Alzheimer's disease. Am J Pathol. 2001 Jan;158(1):189-98.

Bornemann KD, Wiederhold KH, Pauli C, Ermini F, Stalder M, Schnell L, Sommer B, Jucker M, Staufenbiel M. Abeta-induced inflammatory processes in microglia cells of APP23 transgenic mice. Am J Pathol. 2001 Jan;158(1):63-73.

Massi F, Peng JW, Lee JP, Straub JE. Simulation study of the structure and dynamics of the Alzheimer's amyloid peptide congener in solution. Biophys J. 2001 Jan;80(1):31-44.

Thomas T, Bryant M, Clark L, Garces A, Rhodin J. Estrogen and raloxifene activities on amyloid-beta-induced inflammatory reaction. Microvasc Res. 2001 Jan;61(1):28-39.

Wang YC, Tsai SJ, Liu TY, Liu HC, Hong CJ. No association between tryptophan hydroxylase gene polymorphism and Alzheimer's disease. Neuropsychobiology. 2001 Jan;43(1):1-4. ,

Santens P, De Bleecker J, Goethals P, Strijckmans K, Lemahieu I, Slegers G, Dierckx R, De Reuck J. Differential regional cerebral uptake of (18)F-fluoro-2-deoxy-D-glucose in Alzheimer's disease and frontotemporal dementia at initial diagnosis. Eur Neurol. 2001;45(1):19-27.

Le WD, Jankovic J. Are dopamine receptor agonists neuroprotective in Parkinson's disease? Drugs Aging. 2001;18(6):389-96.

Tsolaki M, Sakka V, Gerasimou G, Dimacopoulos N, Chatzizisi O, Fountoulakis KN, Kyriazis G, Papanastasiou J, Kazis A. Correlation of rCBF (SPECT), CSF tau, and cognitive function in patients with dementia of the Alzheimer's type, other types of dementia, and control subjects. Am J Alzheimers Dis Other Demen. 2001 Jan-Feb;16(1):21-31.

Iliev A, Traykov V, Stoykov I, Yakimova K. Estradiol inhibits astrocytic GFAP expression in an animal model of neuroinflammation. Methods Find Exp Clin Pharmacol. 2001 Jan-Feb;23(1):29-35.

Maddock RJ, Garrett AS, Buonocore MH. Remembering familiar people: the posterior cingulate cortex and autobiographical memory retrieval. Neuroscience. 2001;104(3):667-76.

Matsuoka Y, Picciano M, La Francois J, Duff K. Fibrillar beta-amyloid evokes oxidative damage in a transgenic mouse model of Alzheimer's disease. Neuroscience. 2001;104(3):609-13.

López-Arrieta JM, Rodríguez JL, Sanz F. Efficacy and safety of nicotine on Alzheimer's disease patients. Cochrane Database Syst Rev. 2001;(2):CD001749.

Flicker L, Grimley Evans G. Piracetam for dementia or cognitive impairment. Cochrane Database Syst Rev. 2001;(2):CD001011.

Olin J, Schneider L, Novit A, Luczak S. Hydergine for dementia. Cochrane Database Syst Rev. 2001;(2):CD000359.

Huppert FA, Van Niekerk JK. Dehydroepiandrosterone (DHEA) supplementation for cognitive function . Cochrane Database Syst Rev. 2001;(2):CD000304.

Gandy S, Petanceska S. Regulation of alzheimer beta-amyloid precursor trafficking and metabolism. Adv Exp Med Biol. 2001;487:85-100.

Probst A, Mistl C, Ipsen S, Tolnay M. Perisomatic granules of hippocampal CA1 neurons in Alzheimer's disease, pre-Alzheimer stage and Pick's disease: an overlooked pathological entity. Adv Exp Med Biol. 2001;487:187-98.

Yang SY, He XY. Role of type 10 17beta-hydroxysteroid dehydrogenase in the pathogenesis of Alzheimer's disease. Adv Exp Med Biol. 2001;487:101-10.

Rasmusen L, Yan B, Robillard A, Dunbar F. Effects of washout and dose-escalation periods on the efficacy, safety, and tolerability of galantamine in patients previously treated with donepezil: ongoing clinical trials. Clin Ther. 2001;23 Suppl A:A25-30.

Farlow MR. Pharmacokinetic profiles of current therapies for Alzheimer's disease: implications for switching to galantamine. Clin Ther. 2001;23 Suppl A:A13-24.

Coelho F, Birks J. Physostigmine for Alzheimer's disease. Cochrane Database Syst Rev. 2001;(2):CD001499.

Ferris SH. Switching previous therapies for Alzheimer's disease to galantamine. Clin Ther. 2001;23 Suppl A:A3-7.

Morris JC. Therapeutic continuity in Alzheimer's disease: switching patients to galantamine. Introduction. Clin Ther. 2001;23 Suppl A:A1-2.

Honjo H, Kikuchi N, Hosoda T, Kariya K, Kinoshita Y, Iwasa K, Ohkubo T, Tanaka K, Tamura T, Urabe M, Kawata M. Alzheimer's disease and estrogen. J Steroid Biochem Mol Biol. 2001 Jan-Mar;76(1-5):227-30.

Cummings JL. Treatment of Alzheimer's disease. Clin Cornerstone. 2001;3(4):27-39.

DeKosky ST. Epidemiology and pathophysiology of Alzheimer's disease. Clin Cornerstone. 2001;3(4):15-26.

Rodríguez-Martín JL, Qizilbash N, López-Arrieta JM. Thiamine for Alzheimer's disease. Cochrane Database Syst Rev. 2001;(2):CD001498.

Maelicke A. Pharmacokinetic rationale for switching from donepezil to galantamine. Clin Ther. 2001;23 Suppl A:A8-12.

Morris JC, Farlow MR, Ferris SH, Kurz AF, Maelicke A, Rasmusen L, Wilkinson D, Yan B. Therapeutic continuity in Alzheimer's disease: switching patients to galantamine. Panel discussion: recommendations for prescribers. Clin Ther. 2001;23 Suppl A:A31-9.

Ijzerman A, Kourounakis A, van der Klein P. Allosteric modulation of G protein-coupled receptors. Farmaco. 2001 Jan-Feb;56(1-2):67-70.

Adler G, Brassen S. Short-term rivastigmine treatment reduces EEG slow-wave power in Alzheimer patients. Neuropsychobiology. 2001;43(4):273-6.

Allt G, Lawrenson JG. Pericytes: cell biology and pathology. Cells Tissues Organs. 2001;169(1):1-11.

Bennett A. Anti-inflammatory drugs, cyclooxygenases and other factors. Expert Opin Pharmacother. 2001 Jan;2(1):1-2.

Tsai SJ, Hong CJ, Liu TY, Cheng CY, Liu HC. Association study for a functional serotonin transporter gene polymorphism and late-onset Alzheimer's disease for Chinese patients. Neuropsychobiology. 2001;44(1):27-30. , ,

Rösler N, Wichart I, Jellinger KA. Clinical significance of neurobiochemical profiles in the lumbar cerebrospinal fluid of Alzheimer's disease patients. J Neural Transm. 2001;108(2):231-46. ,

Fukuta T, Nitta A, Itoh A, Furukawa S, Nabeshima T. Difference in toxicity of beta-amyloid peptide with aging in relation to nerve growth factor content in rat brain. J Neural Transm. 2001;108(2):221-30.

Dowjat WK, Wisniewski H, Wisniewski T. Alzheimer's disease presenilin-1 expression modulates the assembly of neurofilaments. Neuroscience. 2001;103(1):1-8.

Junceda-Moreno J, Junceda-Moreno C, Suárez-Suárez E, Vidal-Sánchez JA, Junceda-Avello JM. [The use of afterimages in the diagnosis of Alzheimer's disease] Rev Neurol. 2001 Jan 1-15;32(1):38-41.

Thomas A, Iacono D, Bonanni L, D'Andreamatteo G, Onofrj M. Donepezil, rivastigmine, and vitamin E in Alzheimer disease: a combined P300 event-related potentials/neuropsychologic evaluation over 6 months. Clin Neuropharmacol. 2001 Jan-Feb;24(1):31-42.

Tolnay M, Probst A. Frontotemporal lobar degeneration. An update on clinical, pathological and genetic findings. Gerontology. 2001 Jan-Feb;47(1):1-8.

Caine D, Patterson K, Hodges JR, Heard R, Halliday G. Severe anterograde amnesia with extensive hippocampal degeneration in a case of rapidly progressive frontotemporal dementia. Neurocase. 2001;7(1):57-64.

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Sjögren M, Hesse C, Basun H, Köl G, Thostrup H, Kilander L, Marcusson J, Edman A, Wallin A, Karlsson I, Troell M, Wachtmaister G, Ekdahl A, Olofsson H, Sandström A, Andreasen N, Minthon L, Blennow K. Tacrine and rate of progression in Alzheimer's disease--relation to ApoE allele genotype. J Neural Transm. 2001;108(4):451-8.

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Brion JP, Anderton BH, Authelet M, Dayanandan R, Leroy K, Lovestone S, Octave JN, Pradier L, Touchet N, Tremp G. Neurofibrillary tangles and tau phosphorylation. Biochem Soc Symp. 2001;(67):81-8.

Anderton BH, Betts J, Blackstock WP, Brion JP, Chapman S, Connell J, Dayanandan R, Gallo JM, Gibb G, Hanger DP, Hutton M, Kardalinou E, Leroy K, Lovestone S, Mack T, Reynolds CH, Van Slegtenhorst M. Sites of phosphorylation in tau and factors affecting their regulation. Biochem Soc Symp. 2001;(67):73-80.

Goedert M, Spillantini MG. Tau gene mutations and neurodegeneration. Biochem Soc Symp. 2001;(67):59-71.

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Cowburn RF, O'Neill C, Bonkale WL, Ohm TG, Fastbom J. Receptor-G-protein signalling in Alzheimer's disease. Biochem Soc Symp. 2001;(67):163-75.

Mattson MP, Gary DS, Chan SL, Duan W. Perturbed endoplasmic reticulum function, synaptic apoptosis and the pathogenesis of Alzheimer's disease. Biochem Soc Symp. 2001;(67):151-62.

Yan SD, Schmidt AM, Stern D. Alzheimer's disease: inside, outside, upside down. Biochem Soc Symp. 2001;(67):15-22.

Anderson I, Adinolfi C, Doctrow S, Huffman K, Joy KA, Malfroy B, Soden P, Rupniak HT, Barnes JC. Oxidative signalling and inflammatory pathways in Alzheimer's disease. Biochem Soc Symp. 2001;(67):141-9.

von der Kammer H, Demiralay C, Andresen B, Albrecht C, Mayhaus M, Nitsch RM. Regulation of gene expression by muscarinic acetylcholine receptors. Biochem Soc Symp. 2001;(67):131-40.

Ohm TG, Hamker U, Cedazo-Minguez A, Röckl W, Scharnagl H, März W, Cowburn R, Müller W, Meske V. Apolipoprotein E and beta A4-amyloid: signals and effects. Biochem Soc Symp. 2001;(67):121-9.

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Ferrer I, Blanco R, Carmona M, Puig B. Phosphorylated mitogen-activated protein kinase (MAPK/ERK-P), protein kinase of 38 kDa (p38-P), stress-activated protein kinase (SAPK/JNK-P), and calcium/calmodulin-dependent kinase II (CaM kinase II) are differentially expressed in tau deposits in neurons and glial cells in tauopathies. J Neural Transm. 2001;108(12):1397-415.

Nadlinger K, Birkmayer J, Gebauer F, Kunze R. Influence of reduced nicotinamide adenine dinucleotide on the production of interleukin-6 by peripheral human blood leukocytes. Neuroimmunomodulation. 2001;9(4):203-8.

Höschl C, Hajek T. Hippocampal damage mediated by corticosteroids--a neuropsychiatric research challenge. Eur Arch Psychiatry Clin Neurosci. 2001;251 Suppl 2:II81-8.

Blennow K, Vanmechelen E, Hampel H. CSF total tau, Abeta42 and phosphorylated tau protein as biomarkers for Alzheimer's disease. Mol Neurobiol. 2001 Aug-Dec;24(1-3):87-97.

 

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Terai K, Iwai A, Kawabata S, Tasaki Y, Watanabe T, Miyata K, Yamaguchi T. beta-amyloid deposits in transgenic mice expressing human beta-amyloid precursor protein have the same characteristics as those in Alzheimer's disease. Neuroscience. 2001;104(2):299-310.

Williams JH. Frequency-specific effects of flicker on recognition memory. Neuroscience. 2001;104(2):283-6.

Fernández- Lastra A, Morales-Rodríguez M, Penzol-Díaz J. [Neurophysiological study and use of P300 evoked potentials for investigation in the diagnosis and of follow-up of patients with Alzheimer s disease] Rev Neurol. 2001 Mar 16-31;32(6):525-8.

Ojaimi J, Byrne E. Mitochondrial function and alzheimer's disease. Biol Signals Recept. 2001 May-Aug;10(3-4):254-62.

Nishimura AL, Oliveira JR, Otto PA, Matioli SR, Brito-Marques PR, Bahia VS, Nitrini R, Zatz M. No evidence of association between the D10S1423 locus and Alzheimer disease in Brazilian patients. J Neural Transm. 2001;108(3):305-10.

Savoiardo M, Grisoli M. Imaging dementias. Eur Radiol. 2001;11(3):484-92.

Kalaria RN, Ballard CG, Ince PG, Kenny RA, McKeith IG, Morris CM, O'Brien JT, Perry EK, Perry RH, Edwardson JA. Multiple substrates of late-onset dementia: implications for brain protection. Novartis Found Symp. 2001;235:49-60; discussion 60-5.

Bush AI, Goldstein LE. Specific metal-catalysed protein oxidation reactions in chronic degenerative disorders of ageing: focus on Alzheimer's disease and age-related cataracts. Novartis Found Symp. 2001;235:26-38; discussion 38-43.

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Tsolaki M, Pantazi T, Kazis A. Efficacy of acetylcholinesterase inhibitors versus nootropics in Alzheimer's disease: a retrospective, longitudinal study. J Int Med Res. 2001 Jan-Feb;29(1):28-36.

Ferrer I, Blanco R, Carmona M, Puig B, Barrachina M, Gómez C, Ambrosio S. Active, phosphorylation-dependent mitogen-activated protein kinase (MAPK/ERK), stress-activated protein kinase/c-Jun N-terminal kinase (SAPK/JNK), and p38 kinase expression in Parkinson's disease and Dementia with Lewy bodies. J Neural Transm. 2001;108(12):1383-96.

Jones LA, Akhtar S, Wann KT. Induction of Alzheimer phenotype in mouse skin fibroblasts. Proc West Pharmacol Soc. 2001;44:177-80.

Corbo RM, Scacchi R, Vilardo T, Ruggeri M. Polymorphisms in the apolipoprotein E gene regulatory region in relation to coronary heart disease and their effect on plasma apolipoprotein E. Clin Chem Lab Med. 2001 Jan;39(1):2-6.

Duker NJ, Sperling J, Soprano KJ, Druin DP, Davis A, Ashworth R. beta-Amyloid protein induces the formation of purine dimers in cellular DNA. J Cell Biochem. 2001;81(3):393-400.

Milanese M, Lkhayat MI, Zatta P. Inhibitory effect of aluminum on dopamine beta-hydroxylase from bovine adrenal gland. J Trace Elem Med Biol. 2001;15(2-3):139-41.

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Rivière S, Gillette-Guyonnet S, Voisin T, Reynish E, Andrieu S, Lauque S, Salva A, Frisoni G, Nourhashemi F, Micas M, Vellas B. A nutritional education program could prevent weight loss and slow cognitive decline in Alzheimer's disease. J Nutr Health Aging. 2001;5(4):295-9.

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Cheon MS, Fountoulakis M, Cairns NJ, Dierssen M, Herkner K, Lubec G. Decreased protein levels of stathmin in adult brains with Down syndrome and Alzheimer's disease. J Neural Transm Suppl. 2001;(61):281-8.

Kim SH, Nairn AC, Cairns N, Lubec G. Decreased levels of ARPP-19 and PKA in brains of Down syndrome and Alzheimer's disease. J Neural Transm Suppl. 2001;(61):263-72.

Kim SH, Fountoulakis M, Cairns N, Lubec G. Protein levels of human peroxiredoxin subtypes in brains of patients with Alzheimer's disease and Down syndrome. J Neural Transm Suppl. 2001;(61):223-35.

Balcz B, Kirchner L, Cairns N, Fountoulakis M, Lubec G. Increased brain protein levels of carbonyl reductase and alcohol dehydrogenase in Down syndrome and Alzheimer's disease. J Neural Transm Suppl. 2001;(61):193-201.

Nelson PG, McCune SK, Ades AM, Nelson KB. Glial-neurotrophic mechanisms in Down syndrome. J Neural Transm Suppl. 2001;(61):85-94.

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Bernert G, Sustrova M, Sovcikova E, Seidl R, Lubec G. Effects of a single transdermal nicotine dose on cognitive performance in adults with Down syndrome. J Neural Transm Suppl. 2001;(61):237-45.

Kitzmueller E, Greber S, Fountoulakis M, Lubec G. Carbohydrate handling enzymes in fetal Down syndrome brain. J Neural Transm Suppl. 2001;(61):203-10.

Thome J, Retz W, Baader M, Pesold B, Hu M, Cowen M, Durany N, Adler G, Henn FA, Rösler M. Association analysis of HTR6 and HTR2A polymorphisms in sporadic Alzheimer's disease. J Neural Transm. 2001;108(10):1175-80. ,

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