Postdoctoral Fellows – Mitophagy in neurodegenerative diseases
Employer
Mayo Clinic
Location
Jacksonville, Florida
Principal Investigator
Contact
Qualified candidates should send CV, a letter stating research experiences and interests, and contact details of three references to Wolfdieter Springer (Springer.Wolfdieter@mayo.edu).
For an overview of research and laboratory visit: https://www.mayo.edu/research/labs/translational-cell-biology-parkinsons-disease/overview.
Description
Postdoctoral fellowships are available in the laboratory of Wolfdieter Springer to conduct NIH-, DOD-, and MJFF-funded research on mechanisms of neurodegeneration at Mayo Clinic in Jacksonville, Florida. The Springer lab focuses on selective autophagy pathways, in particular mitophagy, and how alterations contribute to Parkinson's disease, Alzheimer's disease, and related disorders. The lab employs a multidisciplinary approach using state-of-the-art techniques in cell biology, biochemistry, and imaging to unravel the underlying disease biology, thereby bridging critical gaps between human genetic, clinical, and neuropathological findings.
Specific research projects include 1) investigation of mitophagy-related mechanisms in Lewy body diseases and tauopathies, 2) studies on phosphorylated ubiquitin as a biomarker for mitophagy in cells, tissues, and biofluids, 3) identification of disease signatures resulting from altered mitophagy, 4) genome-wide analysis of mitophagy modulators, as well as 5) genetic and pharmacological stimulation of mitophagy.
Mayo Clinic and the Department of Neuroscience offer an outstanding research and training environment with a competitive stipend and a generous fringe benefit package.
Requirements
Applications are invited from motivated candidates holding a Ph.D. or M.D./Ph.D. with less than five years of experience and a strong research background in neurobiology, cell biology, or biochemistry. Expertise in structural biology and biophysics and/or induced pluripotent stem cells and gene editing is highly desirable. Candidates should have a record of impactful, peer-reviewed publications.
This article originally appeared in the "https://www.alzforum.org/jobs/postdoctoral-fellows-mitophagy-neurodegenerative-diseases" and has their copyrights. We do not claim copyright on the content. This information is for research purposes only. This Blog is made available by publishers for educational purposes only as well as to give you general information and a general understanding , not to provide specific advice. By using this blog site you understand that there is no client relationship between you and the Blog publisher. The Blog should not be used as a substitute for competent research advice.
No comments:
Post a Comment