Alzheimer’s Research Papers September 2002 ~ Beta Amyloid Blog

Alzheimer’s Research Papers  September 2002 ~ Beta Amyloid Blog   

                                                           

           

Simonovic M, Volz K. Atomic Resolution Structure of a Succinimide Intermediate in E.coli CheY. J Mol Biol. 2002 Sep 27;322(4):663. 

Cedazo-Minguez A, Popescu BO, Ankarcrona M, Nishimura T, Cowburn RF. The presenilin 1 deltaE9 mutation gives enhanced basal phospholipase C activity and a resultant increase in intracellular calcium concentrations. J Biol Chem. 2002 Sep 27;277(39):36646-55.

Lyketsos CG, Lopez O, Jones B, Fitzpatrick AL, Breitner J, DeKosky S. Prevalence of neuropsychiatric symptoms in dementia and mild cognitive impairment: results from the cardiovascular health study. JAMA. 2002 Sep 25;288(12):1475-83.

Powlishta KK, Von Dras DD, Stanford A, Carr DB, Tsering C, Miller JP, Morris JC. The clock drawing test is a poor screen for very mild dementia. Neurology. 2002 Sep 24;59(6):898-903.

Bernoud-Hubac N, Roberts LJ. Identification of oxidized derivatives of neuroketals. Biochemistry. 2002 Sep 24;41(38):11466-71.

Anguiano M, Nowak RJ, Lansbury PT. Protofibrillar islet amyloid polypeptide permeabilizes synthetic vesicles by a pore-like mechanism that may be relevant to type II diabetes. Biochemistry. 2002 Sep 24;41(38):11338-43.

 

Fillit HM. The role of hormone replacement therapy in the prevention of Alzheimer disease. Arch Intern Med. 2002 Sep 23;162(17):1934-42.

Goulas A, Fidani L, Kotsis A, Mirtsou V, Petersen R, Tangalos E, Hardy J. An association study of a functional catalase gene polymorphism, -262C-->T, and patients with Alzheimer's disease. Neurosci Lett. 2002 Sep 20;330(2):210. ,

Fawcett J, Bordayo E, Jackson K, Liu H, Peterson J, Svitak A, Frey W. Inactivation of the human brain muscarinic acetylcholine receptor by oxidative damage catalyzed by a low molecular weight endogenous inhibitor from Alzheimer's brain is prevented by pyrophosphate analogs, bioflavonoids and other antioxidants. Brain Res. 2002 Sep 20;950(1-2):10.

Montilla-López P, Muñoz-Agueda MC, Feijóo López M, Muñoz-Castañeda JR, Bujalance-Arenas I, Túnez-Fiñana I. Comparison of melatonin versus vitamin C on oxidative stress and antioxidant enzyme activity in Alzheimer's disease induced by okadaic acid in neuroblastoma cells. Eur J Pharmacol. 2002 Sep 20;451(3):237-43.

Kang DE, Soriano S, Xia X, Eberhart CG, De Strooper B, Zheng H, Koo EH. Presenilin couples the paired phosphorylation of beta-catenin independent of axin: implications for beta-catenin activation in tumorigenesis. Cell. 2002 Sep 20;110(6):751-62.

Iwatsubo T. [Molecular mechanism of Alzheimer disease] Nippon Naika Gakkai Zasshi. 2002 Sep 20;91 Suppl:149-51.

Mohajeri MH, Wollmer MA, Nitsch RM. Abeta 42-induced increase in neprilysin is associated with prevention of amyloid plaque formation in vivo. J Biol Chem. 2002 Sep 20;277(38):35460-5.

Ethell DW, Kinloch R, Green DR. Metalloproteinase shedding of Fas ligand regulates beta-amyloid neurotoxicity. Curr Biol. 2002 Sep 17;12(18):1595-600.

Luo Y, Smith JV, Paramasivam V, Burdick A, Curry KJ, Buford JP, Khan I, Netzer WJ, Xu H, Butko P. Inhibition of amyloid-beta aggregation and caspase-3 activation by the Ginkgo biloba extract EGb761. Proc Natl Acad Sci U S A. 2002 Sep 17;99(19):12197-202.

Capsoni S, Giannotta S, Cattaneo A. Nerve growth factor and galantamine ameliorate early signs of neurodegeneration in anti-nerve growth factor mice. Proc Natl Acad Sci U S A. 2002 Sep 17;99(19):12432-7.

    

Roher AE, Weiss N, Kokjohn TA, Kuo YM, Kalback W, Anthony J, Watson D, Luehrs DC, Sue L, Walker D, Emmerling M, Goux W, Beach T. Increased Abeta peptides and reduced cholesterol and myelin proteins characterize white matter degeneration in Alzheimer's disease. Biochemistry. 2002 Sep 17;41(37):11080-90.

 

Rijkers DT, Höppener JW, Posthuma G, Lips CJ, Liskamp RM. Inhibition of Amyloid Fibril Formation of Human Amylin by N-Alkylated Amino Acid and alpha-Hydroxy Acid Residue Containing Peptides. Chemistry. 2002 Sep 16;8(18):4285-91.

Pola R, Flex A, Gaetani E, Lago AD, Gerardino L, Pola P, Bernabei R. The -74 G/C polymorphism of the interleukin-6 gene promoter is associated with Alzheimer's disease in an Italian population. Neuroreport. 2002 Sep 16;13(13):1645-7. ,

Alberca R, Montes Latorre E, Gil Neciga E, Mir Rivera P, Lozano San Martin P. [Alzheimer s disease and women] Rev Neurol. 2002 Sep 16;35(6):571-9.

Krishnan KR, Delong M, Kraemer H, Carney R, Spiegel D, Gordon C, McDonald W, Dew M, Alexopoulos G, Buckwalter K, Cohen PD, Evans D, Kaufmann PG, Olin J, Otey E, Wainscott C. Comorbidity of depression with other medical diseases in the elderly. Biol Psychiatry. 2002 Sep 15;52(6):559-88.

Brumwell CL, Johnson JL, Jacob MH. Extrasynaptic alpha 7-nicotinic acetylcholine receptor expression in developing neurons is regulated by inputs, targets, and activity. J Neurosci. 2002 Sep 15;22(18):8101-9.

Dhavan R, Greer PL, Morabito MA, Orlando LR, Tsai LH. The cyclin-dependent kinase 5 activators p35 and p39 interact with the alpha-subunit of Ca2+/calmodulin-dependent protein kinase II and alpha-actinin-1 in a calcium-dependent manner. J Neurosci. 2002 Sep 15;22(18):7879-91.

Bacskai BJ, Kajdasz ST, McLellan ME, Games D, Seubert P, Schenk D, Hyman BT. Non-Fc-mediated mechanisms are involved in clearance of amyloid-beta in vivo by immunotherapy. J Neurosci. 2002 Sep 15;22(18):7873-8.

Meyer J, Xu G, Thornby J, Chowdhury M, Quach M. Longitudinal analysis of abnormal domains comprising mild cognitive impairment (MCI) during aging. J Neurol Sci. 2002 Sep 15;201(1-2):19.

Lemstra AW, Eikelenboom P, Meijer EW, van Gool WA. [Novel therapeutic approach to amyloidosis: no implications as yet for patients with Alzheimer's disease] Ned Tijdschr Geneeskd. 2002 Sep 14;146(37):1720-3.

Head E, Lott I, Cribbs D, Cotman C, Rohn T. beta-Amyloid deposition and neurofibrillary tangle association with caspase activation in Down syndrome. Neurosci Lett. 2002 Sep 13;330(1):99.

Smith IF, Boyle JP, Vaughan PF, Pearson HA, Cowburn RF, Peers CS. Ca(2+) stores and capacitative Ca(2+) entry in human neuroblastoma (SH-SY5Y) cells expressing a familial Alzheimer's disease presenilin-1 mutation. Brain Res. 2002 Sep 13;949(1-2):105-11.

Huang C, Wahlund LO, Svensson L, Winblad B, Julin P. Cingulate cortex hypoperfusion predicts Alzheimer's disease in mild cognitive impairment. BMC Neurol. 2002 Sep 12;2(1):9.

Palumaa P, Njunkova O, Pokras L, Eriste E, Jörnvall H, Sillard R. Evidence for non-isostructural replacement of Zn(2+) with Cd(2+) in the beta-domain of brain-specific metallothionein-3. FEBS Lett. 2002 Sep 11;527(1-3):76.

Garcia JM, Martín JL. Genetic testing for familial Alzheimer's must be debated. BMJ. 2002 Sep 7;325(7363):549.

Pennisi G, Alagona G, Ferri R, Greco S, Santonocito D, Pappalardo A, Bella R. Motor cortex excitability in Alzheimer disease: one year follow-up study. Neurosci Lett. 2002 Sep 6;329(3):293.

Kovacs G, Zerbi P, Voigtländer T, Strohschneider M, Trabattoni G, Hainfellner J, Budka H. The prion protein in human neurodegenerative disorders. Neurosci Lett. 2002 Sep 6;329(3):269.

Dai J, Buijs RM, Kamphorst W, Swaab DF. Impaired axonal transport of cortical neurons in Alzheimer's disease is associated with neuropathological changes. Brain Res. 2002 Sep 6;948(1-2):138-44.

El-Bakri NK, Adem A, Suliman IA, Mulugeta E, Karlsson E, Lindgren JU, Winblad B, Islam A. Estrogen and progesterone treatment: effects on muscarinic M(4) receptor subtype in the rat brain. Brain Res. 2002 Sep 6;948(1-2):131-7.

Yagami T, Ueda K, Asakura K, Kuroda T, Hata S, Sakaeda T, Kambayashi Y, Fujimoto M. Effects of endothelin B receptor agonists on amyloid beta protein (25-35)-induced neuronal cell death. Brain Res. 2002 Sep 6;948(1-2):72-81.

Dvir H, Jiang HL, Wong DM, Harel M, Chetrit M, He XC, Jin GY, Yu GL, Tang XC, Silman I, Bai DL, Sussman JL. X-ray structures of Torpedo californica acetylcholinesterase complexed with (+)-huperzine A and (-)-huperzine B: structural evidence for an active site rearrangement. Biochemistry. 2002 Sep 3;41(35):10810-8.

Johnson LV, Leitner WP, Rivest AJ, Staples MK, Radeke MJ, Anderson DH. The Alzheimer's A beta -peptide is deposited at sites of complement activation in pathologic deposits associated with aging and age-related macular degeneration. Proc Natl Acad Sci U S A. 2002 Sep 3;99(18):11830-5.

 

Elgh E, Sundström T, Näsman B, Ahlström R, Nyberg L. Memory functions and rCBF (99m)Tc-HMPAO SPET: developing diagnostics in Alzheimer's disease. Eur J Nucl Med Mol Imaging. 2002 Sep;29(9):1140-8.

Pan W, Solomon B, Maness LM, Kastin AJ. Antibodies to beta-Amyloid Decrease the Blood-to-Brain Transfer of beta-Amyloid Peptide. Exp Biol Med (Maywood). 2002 Sep;227(8):609-15.

 

Wesemann DR, Dong Y, O'Keefe GM, Nguyen VT, Benveniste EN. Suppressor of cytokine signaling 1 inhibits cytokine induction of CD40 expression in macrophages. J Immunol. 2002 Sep 1;169(5):2354-60.

 

Stein TD, Johnson JA. Lack of neurodegeneration in transgenic mice overexpressing mutant amyloid precursor protein is associated with increased levels of transthyretin and the activation of cell survival pathways. J Neurosci. 2002 Sep 1;22(17):7380-8.

 

Lindsay J, Laurin D, Verreault R, Hébert R, Helliwell B, Hill GB, McDowell I. Risk factors for Alzheimer's disease: a prospective analysis from the Canadian Study of Health and Aging. Am J Epidemiol. 2002 Sep 1;156(5):445-53.

 

Yip AG, Brayne C, Easton D, Rubinsztein DC, Medical Research Council Cognitive Function Ageing Study (MRC CFAS). Apolipoprotein E4 is only a weak predictor of dementia and cognitive decline in the general population. J Med Genet. 2002 Sep;39(9):639-43.

 

Vincent VA, DeVoss JJ, Ryan HS, Murphy GM. Analysis of neuronal gene expression with laser capture microdissection. J Neurosci Res. 2002 Sep 1;69(5):578-86.

Kirkitadze MD, Bitan G, Teplow DB. Paradigm shifts in Alzheimer's disease and other neurodegenerative disorders: the emerging role of oligomeric assemblies. J Neurosci Res. 2002 Sep 1;69(5):567-77.

    

Montine T, Neely M, Quinn J, Beal M, Markesbery W, Roberts L, Morrow J. Lipid peroxidation in aging brain and Alzheimer's disease(1,2). Free Radic Biol Med. 2002 Sep 1;33(5):620.

Anderson DH, Mullins RF, Hageman GS, Johnson LV. A role for local inflammation in the formation of drusen in the aging eye. Am J Ophthalmol. 2002 Sep;134(3):411-31.

Suh YH, Checler F. Amyloid precursor protein, presenilins, and alpha-synuclein: molecular pathogenesis and pharmacological applications in Alzheimer's disease. Pharmacol Rev. 2002 Sep;54(3):469-525.

Sigurdsson E, Wisniewski T, Frangione B. Infectivity of amyloid diseases. Trends Mol Med. 2002 Sep;8(9):411.

Summerfield C, Gómez-Ansón B, Tolosa E, Mercader JM, Martí MJ, Pastor P, Junqué C. Dementia in Parkinson disease: a proton magnetic resonance spectroscopy study. Arch Neurol. 2002 Sep;59(9):1415-20.

  

Fukumoto H, Cheung BS, Hyman BT, Irizarry MC. Beta-secretase protein and activity are increased in the neocortex in Alzheimer disease. Arch Neurol. 2002 Sep;59(9):1381-9.

    

Rosenberg RN. Explaining the cause of the amyloid burden in Alzheimer disease. Arch Neurol. 2002 Sep;59(9):1367-8.

    

Tolu P, Masi F, Leggio B, Scheggi S, Tagliamonte A, De Montis M, Gambarana C. Effects of Long-term Acetyl-L-carnitine Administration in Rats. I. Increased Dopamine Output in Mesocorticolimbic Areas and Protection toward Acute Stress Exposure. Neuropsychopharmacology. 2002 Sep;27(3):410.

Lang CJ, Bergmann M. [Dementias with lewy bodies] Fortschr Neurol Psychiatr. 2002 Sep;70(9):476-94.

Freidel S, Martin-Sölch Ch, Schreiter-Gasser U. [Alzheimer's dementia or cerebral toxoplasmosis? Case study of dementia following toxoplasmosis infection] Nervenarzt. 2002 Sep;73(9):874-8.

Bürger K, Mergner R, Arbusow V, Padberg F, Hampel H. [Late onset Huntington's disease - a differential diagnosis of Alzheimer's disease] Nervenarzt. 2002 Sep;73(9):870-3.

Pantel J, Hüger DR, Kratz B, Minnemann E, Martin M, Schad LR, Essig M, Schröder J. [Structural cerebral changes in subjects with mild cognitive impairment] Nervenarzt. 2002 Sep;73(9):845-50.

Royall DR. Alzheimer disease as a vascular disorder: nosological evidence. Stroke. 2002 Sep;33(9):2147-8; discussion 2147-8.

Siegle GJ, Hasselmo ME. Using connectionist models to guide assessment of psychological disorder. Psychol Assess. 2002 Sep;14(3):263-78.

Noor R, Mittal S, Iqbal J. Superoxide dismutase - applications and relevance to human diseases. Med Sci Monit. 2002 Sep;8(9):RA210-6.

Callahan CM, Unverzagt FW, Hui SL, Perkins AJ, Hendrie HC. Six-item screener to identify cognitive impairment among potential subjects for clinical research. Med Care. 2002 Sep;40(9):771-81.

Sánchez JL, Rodríguez M, Carro J. Neuropsychologic variables in sporadic late-onset Alzheimer disease in patients of spanish nationality: a fast and efficient assessment procedure. Neuropsychiatry Neuropsychol Behav Neurol. 2002 Sep;15(3):207-15.

Glosser G, Gallo J, Duda N, de Vries JJ, Clark CM, Grossman M. Visual perceptual functions predict instrumental activities of daily living in patients with dementia. Neuropsychiatry Neuropsychol Behav Neurol. 2002 Sep;15(3):198-206.

Strauss ME, Sperry SD. An informant-based assessment of apathy in Alzheimer disease. Neuropsychiatry Neuropsychol Behav Neurol. 2002 Sep;15(3):176-83.

Wollmer MA, Papassotiropoulos A, Streffer JR, Grimaldi LM, Kapaki E, Salani G, Paraskevas GP, Maddalena A, De Quervain D, Bieber C, Umbricht D, Lemke U, Bosshardt S, Degonda N, Henke K, Hegi T, Jung HH, Pasch T, Hock C, Nitsch RM. Genetic polymorphisms and cerebrospinal fluid levels of tissue inhibitor of metalloproteinases 1 in sporadic Alzheimer's disease. Psychiatr Genet. 2002 Sep;12(3):155-60. , ,

Lesné S, Blanchet S, Docagne F, Liot G, Plawinski L, MacKenzie ET, Auffray C, Buisson A, Piétu G, Vivien D. Transforming growth factor-beta1-modulated cerebral gene expression. J Cereb Blood Flow Metab. 2002 Sep;22(9):1114-23.

Bacskai BJ, Klunk WE, Mathis CA, Hyman BT. Imaging amyloid-beta deposits in vivo. J Cereb Blood Flow Metab. 2002 Sep;22(9):1035-41.

Tammer AH, Coia G, Cappai R, Fuller S, Masters CL, Hudson P, Underwood JR. Generation of a recombinant Fab antibody reactive with the Alzheimer's disease-related Abeta peptide. Clin Exp Immunol. 2002 Sep;129(3):453-63.

Mulder C, Wahlund LO, Blomberg M, De Jong S, Van Kamp GJ, Scheltens P, Teerlink T. Alzheimer's disease is not associated with altered concentrations of the nitric oxide synthase inhibitor asymmetric dimethylarginine in cerebrospinal fluid. J Neural Transm. 2002 Sep;109(9):1203-8.

Burke WJ. Alzheimer's Disease and Related Disorders Annual 2001. Am J Psychiatry. 2002 Sep 1;159(9):1610-1611.

Silverman DH, Small GW. Prompt identification of Alzheimer's disease with brain PET imaging of a woman with multiple previous diagnoses of other neuropsychiatric conditions. Am J Psychiatry. 2002 Sep;159(9):1482-8.

Sahlas DJ, Bilbao JM, Swartz RH, Black SE. Clasmatodendrosis correlating with periventricular hyperintensity in mixed dementia. Ann Neurol. 2002 Sep;52(3):378-81.

Saito Y, Suzuki K, Nanba E, Yamamoto T, Ohno K, Murayama S. Niemann-Pick type C disease: accelerated neurofibrillary tangle formation and amyloid beta deposition associated with apolipoprotein E epsilon 4 homozygosity. Ann Neurol. 2002 Sep;52(3):351-5.

 

Simons M, Schwärzler F, Lütjohann D, von Bergmann K, Beyreuther K, Dichgans J, Wormstall H, Hartmann T, Schulz JB. Treatment with simvastatin in normocholesterolemic patients with Alzheimer's disease: A 26-week randomized, placebo-controlled, double-blind trial. Ann Neurol. 2002 Sep;52(3):346-50. ,

 

Hsu YY, Schuff N, Du AT, Mark K, Zhu X, Hardin D, Weiner MW. Comparison of automated and manual MRI volumetry of hippocampus in normal aging and dementia. J Magn Reson Imaging. 2002 Sep;16(3):305-10.

Golde TE. Inflammation takes on Alzheimer disease. Nat Med. 2002 Sep;8(9):936-8.

Liolitsa D, Powell J, Lovestone S. Genetic variability in the insulin signalling pathway may contribute to the risk of late onset Alzheimer's disease. J Neurol Neurosurg Psychiatry. 2002 Sep;73(3):261-6. ,

 

Zheng XM. Detecting Regional Cerebral Blood Flow Changes in Alzheimer's Patients After Milameline Treatment: Activation or Baseline SPECT? J Nucl Med Technol. 2002 Sep;30(3):118-22.

Yesavage JA, O'Hara R, Kraemer H, Noda A, Taylor JL, Ferris S, Gély-Nargeot MC, Rosen A, Friedman L, Sheikh J, Derouesné C. Modeling the prevalence and incidence of Alzheimer's disease and mild cognitive impairment. J Psychiatr Res. 2002 Sep-Oct;36(5):281-6.

Eikelenboom P, Hoogendijk WJ, Jonker C, Van Tilburg W. Immunological mechanisms and the spectrum of psychiatric syndromes in Alzheimer's disease. J Psychiatr Res. 2002 Sep-Oct;36(5):269-80.

Astell A, Harley T. Accessing semantic knowledge in dementia: evidence from a word definition task. Brain Lang. 2002 Sep;82(3):312.

Holmlund L, Cortes Toro V, Iverfeldt K. Additive effects of amyloid beta fragment and interleukin-1beta on interleukin-6 secretion in rat primary glial cultures. Int J Mol Med. 2002 Sep;10(3):245-50.

Jankowsky JL, Savonenko A, Schilling G, Wang J, Xu G, Borchelt DR. Transgenic mouse models of neurodegenerative disease: opportunities for therapeutic development. Curr Neurol Neurosci Rep. 2002 Sep;2(5):457-64.

Aisen PS. Anti-inflammatory Agents in Alzheimer's Disease. Curr Neurol Neurosci Rep. 2002 Sep;2(5):405-9.

Wisniewski T, Sigurdsson EM. Immunization treatment approaches in Alzheimer's and prion diseases. Curr Neurol Neurosci Rep. 2002 Sep;2(5):400-4.

Sano M. Prevention of Alzheimer's disease: where we stand. Curr Neurol Neurosci Rep. 2002 Sep;2(5):392-9.

Marder K. Efficacy of galantamine in probable vascular dementia and Alzheimer's disease combined with cerebrovascular disease: a randomized trial. Curr Neurol Neurosci Rep. 2002 Sep;2(5):389-90.

 

Jackson R, McNeil B, Taylor C, Holl G, Ruff D, Gwebu ET. Effect of aged garlic extract on caspase-3 activity, in vitro. Nutr Neurosci. 2002 Sep;5(4):287-90.

Butterfield DA, Castegna A, Drake J, Scapagnini G, Calabrese V. Vitamin E and neurodegenerative disorders associated with oxidative stress. Nutr Neurosci. 2002 Sep;5(4):229-39.

Cash AD, Perry G, Smith MA. Therapeutic potential in Alzheimer disease. Curr Med Chem. 2002 Sep;9(17):1605-10.

Hänninen T, Hallikainen M, Tuomainen S, Vanhanen M, Soininen H. Prevalence of mild cognitive impairment: a population-based study in elderly subjects. Acta Neurol Scand. 2002 Sep;106(3):148-54.

 

Mattila KM, Rinne JO, Röyttä M, Laippala P, Lehtimäki T. Lack of association between an estrogen receptor 1 gene polymorphism and Parkinson's disease with dementia. Acta Neurol Scand. 2002 Sep;106(3):128-130.

Giri R, Selvaraj S, Miller CA, Hofman F, Yan SD, Stern D, Zlokovic BV, Kalra VK. Effect of endothelial cell polarity on beta-amyloid-induced migration of monocytes across normal and AD endothelium. Am J Physiol Cell Physiol. 2002 Sep;283(3):C895-904.

 

Liu Y, Qin L, Wilson BC, An L, Hong JS, Liu B. Inhibition by Naloxone Stereoisomers of beta-Amyloid Peptide (1-42)-induced Superoxide Production in Microglia and Degeneration of Cortical and Mesencephalic Neurons. J Pharmacol Exp Ther. 2002 Sep 1;302(3):1212-1219.

 

Perry T, Haughey NJ, Mattson MP, Egan JM, Greig NH. Protection and reversal of excitotoxic neuronal damage by glucagon-like Peptide-1 and exendin-4. J Pharmacol Exp Ther. 2002 Sep;302(3):881-8.

 

Giffard B, Desgranges B, Nore-Mary F, Lalevée C, Beaunieux H, De La Sayette V, Pasquier F, Eustache F. The dynamic time course of semantic memory impairment in Alzheimer's disease: clues from hyperpriming and hypopriming effects. Brain. 2002 Sep;125(Pt 9):2044-2057.

 

Wei W, Norton DD, Wang X, Kusiak JW. Abeta 17-42 in Alzheimer's disease activates JNK and caspase-8 leading to neuronal apoptosis. Brain. 2002 Sep;125(Pt 9):2036-43.

 

Koutsilieri E, Scheller C, Tribl F, Riederer P. Degeneration of neuronal cells due to oxidative stress-microglial contribution. Parkinsonism Relat Disord. 2002 Sep;8(6):401.

Reutens S, Sachdev P. Homocysteine in neuropsychiatric disorders of the elderly. Int J Geriatr Psychiatry. 2002 Sep;17(9):859-64.

Youn JC, Lee DY, Kim KW, Lee JH, Jhoo JH, Lee KU, Ha J, Woo JI. Development of the Korean version of Alzheimer's Disease Assessment Scale (ADAS-K). Int J Geriatr Psychiatry. 2002 Sep;17(9):797-803.

Erkinjuntti T. Broad therapeutic benefits in patients with probable vascular dementia or Alzheimer's disease with cerebrovascular disease after treatment with galantamine. Eur J Neurol. 2002 Sep;9(5):541-5.

Panegyres PK, Zafiris-Toufexis K. Polymorphisms in the tau gene in sporadic frontotemporal dementia and other neurodegenerative disorders. Eur J Neurol. 2002 Sep;9(5):485-9.

Food MR, Sekyere EO, Richardson DR. The soluble form of the membrane-bound transferrin homologue, melanotransferrin, inefficiently donates iron to cells via nonspecific internalization and degradation of the protein. Eur J Biochem. 2002 Sep;269(18):4435-45.

Zheng YL, Li BS, Amin ND, Albers W, Pant HC. A peptide derived from cyclin-dependent kinase activator (p35) specifically inhibits Cdk5 activity and phosphorylation of tau protein in transfected cells. Eur J Biochem. 2002 Sep;269(18):4427-34.

Marcinkiewicz M. BetaAPP and furin mRNA concentrates in immature senile plaques in the brain of Alzheimer patients. J Neuropathol Exp Neurol. 2002 Sep;61(9):815-29.

Klunk WE, Bacskai BJ, Mathis CA, Kajdasz ST, McLellan ME, Frosch MP, Debnath ML, Holt DP, Wang Y, Hyman BT. Imaging Abeta plaques in living transgenic mice with multiphoton microscopy and methoxy-X04, a systemically administered Congo red derivative. J Neuropathol Exp Neurol. 2002 Sep;61(9):797-805.

 

Saito Y, Nakahara K, Yamanouchi H, Murayama S. Severe involvement of ambient gyrus in dementia with grains. J Neuropathol Exp Neurol. 2002 Sep;61(9):789-96.

Friedman JH, Fernandez HH. Atypical antipsychotics in Parkinson-sensitive populations. J Geriatr Psychiatry Neurol. 2002 Fall;15(3):156-70.

Nakaya T, Toshiharu S. [The molecular mechanisms of Alzheimer's disease: approach from the amyloid precursor protein] Tanpakushitsu Kakusan Koso. 2002 Sep;47(11):1405-14.

Piggott M, Owens J, O'Brien J, Paling S, Wyper D, Fenwick J, Johnson M, Perry R, Perry E. Comparative distribution of binding of the muscarinic receptor ligands pirenzepine, AF-DX 384, (R,R)-I-QNB and (R,S)-I-QNB to human brain. J Chem Neuroanat. 2002 Sep;24(3):211.

Wilkinson DG, Hock C, Farlow M, van Baelen B, Schwalen S. Galantamine provides broad benefits in patients with 'advanced moderate' Alzheimer's disease (MMSE < or = 12) for up to six months. Int J Clin Pract. 2002 Sep;56(7):509-14.

McDonald RJ. Multiple combinations of co-factors produce variants of age-related cognitive decline: a theory. Can J Exp Psychol. 2002 Sep;56(3):221-39.

Ruel J, Guitton MJ, Puell JL. Negative allosteric modulation of AMPA-preferring receptors by the selective isomer GYKI 53784 (LY303070), a specific non-competitive AMPA antagonist. CNS Drug Rev. 2002 Fall;8(3):235-54.

Bright P, Jaldow E, Kopelman MD. The National Adult Reading Test as a measure of premorbid intelligence: a comparison with estimates derived from demographic variables. J Int Neuropsychol Soc. 2002 Sep;8(6):847-54.

Morgan CD, Murphy C. Olfactory event-related potentials in Alzheimer's disease. J Int Neuropsychol Soc. 2002 Sep;8(6):753-63.

Vale FA, Miranda SJ. Clinical and demographic features of patients with dementia attended in a tertiary outpatient clinic. Arq Neuropsiquiatr. 2002 Sep;60(3-A):548-52.

Palmer AM. Pharmacotherapy for Alzheimer's disease: progress and prospects. Trends Pharmacol Sci. 2002 Sep;23(9):426-33.

Knockaert M, Greengard P, Meijer L. Pharmacological inhibitors of cyclin-dependent kinases. Trends Pharmacol Sci. 2002 Sep 1;23(9):417-25.

 

Combarros O, Sánchez-Guerra M, Infante J, Llorca J, Berciano J. Gene dose-dependent association of interleukin-1A [-889] allele 2 polymorphism with Alzheimer's disease. J Neurol. 2002 Sep;249(9):1242-5. ,

Panza F, Solfrizzi V, D'Introno A, Capurso C, Colacicco AM, Torres F, Altomare E, Capurso A. [In Process Citation] Recenti Prog Med. 2002 Sep;93(9):489-97.

Park SY, Kim DS. Discovery of natural products from Curcuma longa that protect cells from beta-amyloid insult: a drug discovery effort against Alzheimer's disease. J Nat Prod. 2002 Sep;65(9):1227-31.

Lev N, Melamed E. [Neurological complications in Down's Syndrome] Harefuah. 2002 Sep;141(9):820-3, 857.

Ariel A, Osimani A, Korczyn AD. [The real and ideal in the evaluation of functional competence among demented patients] Harefuah. 2002 Sep;141(9):795-8, 858.

Korolainen MA, Goldsteins G, Alafuzoff I, Koistinaho J, Pirttilä T. Proteomic analysis of protein oxidation in Alzheimer's disease brain. Electrophoresis. 2002 Sep;23(19):3428-33.

Devenny DA, Zimmerli EJ, Kittler P, Krinsky-McHale SJ. Cued recall in early-stage dementia in adults with Down's syndrome. J Intellect Disabil Res. 2002 Sep;46(Pt 6):472-83.

Li J, Pauley AM, Myers RL, Shuang R, Brashler JR, Yan R, Buhl AE, Ruble C, Gurney ME. SEL-10 interacts with presenilin 1, facilitates its ubiquitination, and alters A-beta peptide production. J Neurochem. 2002 Sep;82(6):1540-8.

 

Castegna A, Aksenov M, Thongboonkerd V, Klein JB, Pierce WM, Booze R, Markesbery WR, Butterfield DA. Proteomic identification of oxidatively modified proteins in Alzheimer's disease brain. Part II: dihydropyrimidinase-related protein 2, alpha-enolase and heat shock cognate 71. J Neurochem. 2002 Sep;82(6):1524-32.

Russo C, Violani E, Salis S, Venezia V, Dolcini V, Damonte G, Benatti U, D'Arrigo C, Patrone E, Carlo P, Schettini G. Pyroglutamate-modified amyloid beta-peptides--AbetaN3(pE)--strongly affect cultured neuron and astrocyte survival. J Neurochem. 2002 Sep 1;82(6):1480-9.

 

Vincent VA, Robinson CC, Simsek D, Murphy GM. Macrophage colony stimulating factor prevents NMDA-induced neuronal death in hippocampal organotypic cultures. J Neurochem. 2002 Sep;82(6):1388-97.

Corcoran KA, Lu Y, Turner RS, Maren S. Overexpression of hAPPswe impairs rewarded alternation and contextual fear conditioning in a transgenic mouse model of Alzheimer's disease. Learn Mem. 2002 Sep-Oct;9(5):243-52.

Capsoni S, Giannotta S, Cattaneo A. Beta-amyloid plaques in a model for sporadic Alzheimer's disease based on transgenic anti-nerve growth factor antibodies. Mol Cell Neurosci. 2002 Sep 1;21(1):15-28.

    

Taylor DL, Diemel LT, Cuzner ML, Pocock JM. Activation of group II metabotropic glutamate receptors underlies microglial reactivity and neurotoxicity following stimulation with chromogranin A, a peptide up-regulated in Alzheimer's disease. J Neurochem. 2002 Sep;82(5):1179-91.

Yamamoto A, Shin RW, Hasegawa K, Naiki H, Sato H, Yoshimasu F, Kitamoto T. Iron (III) induces aggregation of hyperphosphorylated tau and its reduction to iron (II) reverses the aggregation: implications in the formation of neurofibrillary tangles of Alzheimer's disease. J Neurochem. 2002 Sep;82(5):1137-47.

 

Garzon D, Yu G, Fahnestock M. A new brain-derived neurotrophic factor transcript and decrease in brain-derived neurotrophic factor transcripts 1, 2 and 3 in Alzheimer's disease parietal cortex. J Neurochem. 2002 Sep 1;82(5):1058-64.

Velez-Pardo C, Ospina GG, Jimenez Del Rio M. Abeta[25-35] peptide and iron promote apoptosis in lymphocytes by an oxidative stress mechanism: involvement of H2O2, caspase-3, NF-kappaB, p53 and c-Jun. Neurotoxicology. 2002 Sep;23(3):351-65.

Wan W, DePetrillo PB. Ritonavir protects hippocampal neurons against oxidative stress-induced apoptosis. Neurotoxicology. 2002 Sep;23(3):301-6.

Ahmed I, John A, Vijayasarathy C, Robin MA, Raza H. Differential modulation of growth and glutathione metabolism in cultured rat astrocytes by 4-hydroxynonenal and green tea polyphenol, epigallocatechin-3-gallate. Neurotoxicology. 2002 Sep;23(3):289-300.

Zink M, Sartorius A, Lederbogen F, Henn FA. Electroconvulsive therapy in a patient receiving rivastigmine. J ECT. 2002 Sep;18(3):162-4.

Taylor DH, Fillenbaum GG, Ezell ME. The accuracy of medicare claims data in identifying Alzheimer's disease. J Clin Epidemiol. 2002 Sep;55(9):929-37.

Maguire-Zeiss KA, Bowers WJ, Federoff HJ. Somatic mosaic approaches and the aging brain. Neurobiol Aging. 2002 Sep-Oct;23(5):977.

Forloni G, Terreni L, Bertani I, Fogliarino S, Invernizzi R, Assini A, Ribizzi G, Negro A, Calabrese E, Volonté MA, Mariani C, Franceschi M, Tabaton M, Bertoli A. Protein misfolding in Alzheimer's and Parkinson's disease: genetics and molecular mechanisms. Neurobiol Aging. 2002 Sep-Oct;23(5):957-76.

 

Floyd RA, Hensley K. Oxidative stress in brain aging. Implications for therapeutics of neurodegenerative diseases. Neurobiol Aging. 2002 Sep-Oct;23(5):795.

Klegeris A, McGeer PL. Cyclooxygenase and 5-lipoxygenase inhibitors protect against mononuclear phagocyte neurotoxicity. Neurobiol Aging. 2002 Sep-Oct;23(5):787.

Colton CA, Brown CM, Cook D, Needham LK, Xu Q, Czapiga M, Saunders AM, Schmechel DE, Rasheed K, Vitek MP. APOE and the regulation of microglial nitric oxide production: a link between genetic risk and oxidative stress. Neurobiol Aging. 2002 Sep-Oct;23(5):777-85.

Esposito E, Rotilio D, Di Matteo V, Di Giulio C, Cacchio M, Algeri S. A review of specific dietary antioxidants and the effects on biochemical mechanisms related to neurodegenerative processes. Neurobiol Aging. 2002 Sep-Oct;23(5):719.

Mattson MP, Duan W, Chan SL, Cheng A, Haughey N, Gary DS, Guo Z, Lee J, Furukawa K. Neuroprotective and neurorestorative signal transduction mechanisms in brain aging: modification by genes, diet and behavior. Neurobiol Aging. 2002 Sep-Oct;23(5):695.

Wood WG, Schroeder F, Igbavboa U, Avdulov NA, Chochina SV. Brain membrane cholesterol domains, aging and amyloid beta-peptides. Neurobiol Aging. 2002 Sep-Oct;23(5):685.

Pasinetti GM, Ho L, Pompl P. AN1792 vaccination immunotherapy in Alzheimer's disease: the case of a therapy before its time. Neurobiol Aging. 2002 Sep-Oct;23(5):683.

Schenk DB, Yednock T. The role of microglia in Alzheimer's disease: friend or foe? Neurobiol Aging. 2002 Sep-Oct;23(5):677.

Pasinetti GM, Ho L, Pompl P. Amyloid immunization in Alzheimer's disease: do we promote amyloid scavenging at the cost of inflammatory degeneration? Neurobiol Aging. 2002 Sep-Oct;23(5):665.

Allan Butterfield D, Castegna A, Lauderback CM, Drake J. Evidence that amyloid beta-peptide-induced lipid peroxidation and its sequelae in Alzheimer's disease brain contribute to neuronal death. Neurobiol Aging. 2002 Sep-Oct;23(5):655.

Craft DL, Wein LM, Selkoe DJ. A mathematical model of the impact of novel treatments on the A beta burden in the Alzheimer's brain, CSF and plasma. Bull Math Biol. 2002 Sep;64(5):1011-31.

 

Bastianetto S, Quirion R. EGb 761 is a neuroprotective agent against beta-amyloid toxicity. Cell Mol Biol (Noisy-le-grand). 2002 Sep;48(6):693-7.

Zhuang H, Pin S, Christen Y, Doré S. Induction of heme oxygenase 1 by Ginkgo biloba in neuronal cultures and potential implications in ischemia. Cell Mol Biol (Noisy-le-grand). 2002 Sep;48(6):647-53.

Zimmermann M, Colciaghi F, Cattabeni F, Di Luca M. Ginkgo biloba extract: from molecular mechanisms to the treatment of Alzhelmer's disease. Cell Mol Biol (Noisy-le-grand). 2002 Sep;48(6):613-23.

Shen Y, Yu Y, Guo H, Tang Z, Yu FS, Zhou J. Identification and comparative analysis of differentially expressed proteins in rat striatum following 6-hydroxydopamine lesions of the nigrostriatal pathway: up-regulation of amyloid precursor-like protein 2 expression. Eur J Neurosci. 2002 Sep;16(5):896-906.

Heun R, Kockler M, Ptok U. Depression in Alzheimer's disease: is there a temporal relationship between the onset of depression and the onset of dementia? Eur Psychiatry. 2002 Sep;17(5):254-8.

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Matsubara E, Shoji M, Abe K, Frangione B, Ghiso J. Vascular Amyloidosis in Neurodegenerative Conditions. Drug News Perspect. 2002 Sep;15(7):439-444.

Karlawish JH, Knopman D, Clark CM, Morris JC, Marson D, Whitehouse PJ, Kawas CH. Informed consent for Alzheimer's disease clinical trials: a survey of clinical investigators. IRB. 2002 Sep-Oct;24(5):1-5.

Aisen PS. The potential of anti-inflammatory drugs for the treatment of Alzheimer's disease. Lancet Neurol. 2002 Sep;1(5):279-84.

Taylor WD, Krishnan KR. Management of late-life depression: focus on comorbid conditions. Psychopharmacol Bull. 2002 Autumn;36(4 Suppl 3):113-30.

Wersinger C, Sidhu A. Inflammation and Parkinson's disease. Curr Drug Targets Inflamm Allergy. 2002 Sep;1(3):221-42.

Nocera S, Bonato D, Telser H. The contingency of contingent valuation. How much are people willing to pay against Alzheimer's disease? Int J Health Care Finance Econ. 2002 Sep;2(3):219-40.

Waldman AD, Rai GS, McConnell JR, Chaudry M, Grant D. Clinical brain proton magnetic resonance spectroscopy for management of Alzheimer's and sub-cortical ischemic vascular dementia in older people. Arch Gerontol Geriatr. 2002 Sep-Oct;35(2):137-42.

Brun A, Englund E. Regional pattern of degeneration in Alzheimer's disease: neuronal loss and histopathological grading. Histopathology. 2002 Sep;41(3A):40-55.

Li J, Pauley , Myers , Shuang , Brashler , Yan , Buhl , Ruble , Gurney . SEL-10 interacts with presenilin 1, facilitates its ubiquitination, and alters Ab peptide production. J Neurochem. 2002 Sep;82(6):1540-8. Abstract

Zambrano N, Bimonte , Arbucci , Gianni , Russo , Bazzicalupo . FEH-1 and APL-1, the Caenorhabditis elegans orthologues of mammalian Fe65 and b-amyloid precursor protein genes, are involved in the same pathway that controls nematode pharyngeal pumping. J Cell Sci. 2002 Sep;115(Pt. 7):1411-22. Abstract

Cheng LL, Newell K, Mallory AE, Hyman BT, Gonzalez RG. Quantification of neurons in Alzheimer and control brains with ex vivo high resolution magic angle spinning proton magnetic resonance spectroscopy and stereology. Magn Reson Imaging. 2002 Sep;20(7):527-33.

White KG, Ruske AC. Memory deficits in Alzheimer's disease: the encoding hypothesis and cholinergic function. Psychon Bull Rev. 2002 Sep;9(3):426-37.

Maezawa I, Wang B, Hu Q, Martin GM, Jin LW, Oshima J. Alterations of chaperone protein expression in presenilin mutant neurons in response to glutamate excitotoxicity. Pathol Int. 2002 Sep;52(9):551-4. ,

Brun A, Englund E. Regional pattern of degeneration in Alzheimer's disease: neuronal loss and histopathological grading. A. Brun & E. Englund. Histopathology 1981; 5; 549-564. Histopathology. 2002 Sep;41(3A):37-8, discussion 38-9.

Aguilar-Gaytán R, Mas-Oliva J. [In Process Citation] Gac Med Mex. 2002 Sep-Oct;138(5):445-60.

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Takayama N, Iseki E, Yamamoto T, Kosaka K. Regional quantitative study of formation process of neurofibrillary tangles in the hippocampus of non-demented elderly brains: comparison with late-onset Alzheimer's disease brains. Neuropathology. 2002 Sep;22(3):147-53.

Yuspeh RL, Vanderploeg RD, Crowell TA, Mullan M. Differences in executive functioning between Alzheimer's disease and subcortical ischemic vascular dementia. J Clin Exp Neuropsychol. 2002 Sep;24(6):745-54.

Fahlander K, Wahlin A, Almkvist O, Bäckman L. Cognitive functioning in Alzheimer's disease and vascular dementia: further evidence for similar patterns of deficits. J Clin Exp Neuropsychol. 2002 Sep;24(6):734-44.

Qian YH, Liu Y, Hu HT, Ren HM, Chen XL, Xu JH. The effects of the total saponin of Dipsacus asperoides on the damage of cultured neurons induced by beta-amyloid protein 25-35. Anat Sci Int. 2002 Sep;77(3):196-200.

Shirabe T, Irie K, Uchida M. Autopsy case of aluminum encephalopathy. Neuropathology. 2002 Sep;22(3):206-10.

Falk WE, Daly EJ, Tsai GE, Gunther J, Brown P. A case series of D-cycloserine added to donepezil in the treatment of Alzheimer's disease. J Neuropsychiatry Clin Neurosci. 2002 Fall;14(4):466-7.

Morimoto K, Murasugi T, Oda T. Acute neuroinflammation exacerbates excitotoxicity in rat hippocampus in vivo. Exp Neurol. 2002 Sep;177(1):95-104.

Paris D, Townsend KP, Obregon DF, Humphrey J, Mullan M. Pro-inflammatory effect of freshly solubilized beta-amyloid peptides in the brain. Prostaglandins Other Lipid Mediat. 2002 Sep;70(1-2):1-12.

Aguillón JC, Cruzat A, Cuenca J, Cuchacovich M. [In Process Citation] Rev Med Chil. 2002 Sep;130(9):1043-50.

Bognar SK, Furac I, Kubat M, Cosovic C, Demarin V. Croatian population data for arylsulfatase a pseudodeficiency-associated mutations in healthy subjects, and in patients with Alzheimer-type dementia and Down syndrome. Arch Med Res. 2002 Sep-Oct;33(5):473-7.

Suzuki T, Tozuka M, Kazuyoshi Y, Sugano M, Nakabayashi T, Okumura N, Hidaka H, Katsuyama T, Higuchi K. Predominant apolipoprotein J exists as lipid-poor mixtures in cerebrospinal fluid. Ann Clin Lab Sci. 2002 Fall;32(4):369-76.

Castelli P, Sosa AL, Campillo C, Nicolini H, Cruz-Fuentes C. Apolipoprotein E genotypes in a group of elderly subjects of Spanish descent living in Mexico City. Int Psychogeriatr. 2002 Sep;14(3):291-300.

Ward A, Caro JJ, Kelley H, Eggleston A, Molloy W. Describing cognitive decline of patients at the mild or moderate stages of Alzheimer's disease using the Standardized MMSE. Int Psychogeriatr. 2002 Sep;14(3):249-58.

Hassing LB, Johansson B, Nilsson SE, Berg S, Pedersen NL, Gatz M, McClearn G. Diabetes mellitus is a risk factor for vascular dementia, but not for Alzheimer's disease: a population-based study of the oldest old. Int Psychogeriatr. 2002 Sep;14(3):239-48.

Herholz K, Salmon E, Perani D, Baron JC, Holthoff V, Frölich L, Schönknecht P, Ito K, Mielke R, Kalbe E, Zündorf G, Delbeuck X, Pelati O, Anchisi D, Fazio F, Kerrouche N, Desgranges B, Eustache F, Beuthien-Baumann B, Menzel C, Schröder J, Kato T, Arahata Y, Henze M, Heiss WD. Discrimination between Alzheimer dementia and controls by automated analysis of multicenter FDG PET. Neuroimage. 2002 Sep 1;17(1):302-16.

Good CD, Scahill RI, Fox NC, Ashburner J, Friston KJ, Chan D, Crum WR, Rossor MN, Frackowiak RS. Automatic differentiation of anatomical patterns in the human brain: validation with studies of degenerative dementias. Neuroimage. 2002 Sep;17(1):29-46.

Petrozzi L, Lucetti C, Scarpato R, Gambaccini G, Trippi F, Bernardini S, Del Dotto P, Migliore L, Bonuccelli U. Cytogenetic alterations in lymphocytes of Alzheimer's disease and Parkinson's disease patients. Neurol Sci. 2002 Sep;23 Suppl 2:S97-8.

Parnetti L, Amici S, Lanari A, Romani C, Antognelli C, Andreasen N, Minthon L, Davidsson P, Pottel H, Blennow K, Gallai V. Cerebrospinal fluid levels of biomarkers and activity of acetylcholinesterase (AChE) and butyrylcholinesterase in AD patients before and after treatment with different AChE inhibitors. Neurol Sci. 2002 Sep;23 Suppl 2:S95-6. ,

Calzetti S, Bortone E, Negrotti A, Zinno L, Mancia D. Frontal intermittent rhythmic delta activity (FIRDA) in patients with dementia with Lewy bodies: a diagnostic tool? Neurol Sci. 2002 Sep;23 Suppl 2:S65-6.

Havel J, Patocka J, Bocaz G. Determination of physostigmine and pyridostigmine in pharmaceutical formulations by capillary electrophoresis. J Capillary Electrophor. 2002 Sep-Dec;7(5-6):107-12.

Pasinetti GM. Cyclooxygenase as a target for the antiamyloidogenic activities of nonsteroidal anti-inflammatory drugs in Alzheimer's disease. Neurosignals. 2002 Sep-Oct;11(5):293-7.

Lee HG, Zhu X, Ghanbari HA, Ogawa O, Raina AK, O'Neill MJ, Perry G, Smith MA. Differential regulation of glutamate receptors in Alzheimer's disease. Neurosignals. 2002 Sep-Oct;11(5):282-92.

Zhu X, Lee HG, Raina AK, Perry G, Smith MA. The role of mitogen-activated protein kinase pathways in Alzheimer's disease. Neurosignals. 2002 Sep-Oct;11(5):270-81.

Tian Q, Wang J. Role of serine/threonine protein phosphatase in Alzheimer's disease. Neurosignals. 2002 Sep-Oct;11(5):262-9.