Alzheimer’s Research Papers September 2001

Alzheimer’s Research Papers     

Rockenstein E, Hansen LA, Mallory M, Trojanowski JQ, Galasko D, Masliah E. Altered expression of the synuclein family mRNA in Lewy body and Alzheimer's disease. Brain Res. 2001 Sep 28;914(1-2):48-56.

Yan R, Han P, Miao H, Greengard P, Xu H. The transmembrane domain of the Alzheimer's beta-secretase (BACE1) determines its late Golgi localization and access to beta -amyloid precursor protein (APP) substrate. J Biol Chem. 2001 Sep 28;276(39):36788-96.

 

Getsios D, Caro JJ, Caro G, Ishak K, AHEAD Study Group. Assessment of health economics in Alzheimer's disease (AHEAD): galantamine treatment in Canada. Neurology. 2001 Sep 25;57(6):972-8.

Caro JJ, Getsios D, Migliaccio-Walle K, Raggio G, Ward A, AHEAD Study Group. Assessment of health economics in Alzheimer's disease (AHEAD) based on need for full-time care. Neurology. 2001 Sep 25;57(6):964-71.

Neumann PJ, Araki SS, Arcelus A, Longo A, Papadopoulos G, Kosik KS, Kuntz KM, Bhattacharjya A. Measuring Alzheimer's disease progression with transition probabilities: estimates from CERAD. Neurology. 2001 Sep 25;57(6):957-64.

Raffai RL, Dong LM, Farese RV, Weisgraber KH. Introduction of human apolipoprotein E4 "domain interaction" into mouse apolipoprotein E. Proc Natl Acad Sci U S A. 2001 Sep 25;98(20):11587-91.

Selkoe DJ. Presenilin, Notch, and the genesis and treatment of Alzheimer's disease. Proc Natl Acad Sci U S A. 2001 Sep 25;98(20):11039-41.

 

Barañano DE, Snyder SH. Neural roles for heme oxygenase: contrasts to nitric oxide synthase. Proc Natl Acad Sci U S A. 2001 Sep 25;98(20):10996-1002.

Simons M, Keller P, Dichgans J, Schulz JB. Cholesterol and Alzheimer's disease: is there a link? Neurology. 2001 Sep 25;57(6):1089-93.

Chandra V, Pandav R, Dodge HH, Johnston JM, Belle SH, DeKosky ST, Ganguli M. Incidence of Alzheimer's disease in a rural community in India: the Indo-US study. Neurology. 2001 Sep 25;57(6):985-9.

Yasojima K, Tourtellotte WW, McGeer EG, McGeer PL. Marked increase in cyclooxygenase-2 in ALS spinal cord: implications for therapy. Neurology. 2001 Sep 25;57(6):952-6.

Sun J, Li M, Han J, Gu J. Sensitization of differentiated PC12 cells to apoptosis by presenilin-2 is mediated by p38. Biochem Biophys Res Commun. 2001 Sep 21;287(2):536-41.

Marx J. Neuroscience. New leads on the 'how' of Alzheimer's. Science. 2001 Sep 21;293(5538):2192-4.

Cowley G. Alzheimer's. A dignity in dementia. Newsweek. 2001 Sep 17;138(12):58.

Exley C, Korchazhkina OV. Plasmin cleaves Abeta42 in vitro and prevents its aggregation into beta-pleated sheet structures. Neuroreport. 2001 Sep 17;12(13):2967-70.

Yasojima K, McGeer EG, McGeer PL. 3-hydroxy-3-methylglutaryl-coenzyme A reductase mRNA in Alzheimer and control brain. Neuroreport. 2001 Sep 17;12(13):2935-8.

Furuta A, Iida T, Nakabeppu Y, Iwaki T. Expression of hMTH1 in the hippocampi of control and Alzheimer's disease. Neuroreport. 2001 Sep 17;12(13):2895-9.

Brodaty H, Ames D, Boundy KL, Hecker J, Snowdon J, Storey E, Yates MW. Pharmacological treatment of cognitive deficits in Alzheimer's disease. Med J Aust. 2001 Sep 17;175(6):324-9.

Lin A, Nguy CH, Shic F, Ross BD. Accumulation of methylsulfonylmethane in the human brain: identification by multinuclear magnetic resonance spectroscopy. Toxicol Lett. 2001 Sep 15;123(2-3):169-77.

Smith DS. Health care management of adults with Down syndrome. Am Fam Physician. 2001 Sep 15;64(6):1031-8.

Rea IM, Mc Dowell I, McMaster D, Smye M, Stout R, Evans A, MONICA group (Belfast). Monitoring of Cardiovascular trends study group. Apolipoprotein E alleles in nonagenarian subjects in the Belfast Elderly Longitudinal Free-living Ageing Study (BELFAST). Mech Ageing Dev. 2001 Sep 15;122(13):1367-72.

Stoothoff WH, Johnson GV. Hyperosmotic stress-induced apoptosis and tau phosphorylation in human neuroblastoma cells. J Neurosci Res. 2001 Sep 15;65(6):573-82.

Pasinetti GM. Use of cDNA microarray in the search for molecular markers involved in the onset of Alzheimer's disease dementia. J Neurosci Res. 2001 Sep 15;65(6):471-6.

Michikawa M, Gong JS, Fan QW, Sawamura N, Yanagisawa K. A novel action of alzheimer's amyloid beta-protein (Abeta): oligomeric Abeta promotes lipid release. J Neurosci. 2001 Sep 15;21(18):7226-35.

Nacmias B, Tedde A, Forleo P, Piacentini S, Guarnieri BM, Bartoli A, Ortenzi L, Petruzzi C, Serio A, Marcon G, Sorbi S. Association between 5-HT(2A) receptor polymorphism and psychotic symptoms in Alzheimer's disease. Biol Psychiatry. 2001 Sep 15;50(6):472-5. ,

Lüth HJ, Holzer M, Gärtner U, Staufenbiel M, Arendt T. Expression of endothelial and inducible NOS-isoforms is increased in Alzheimer's disease, in APP23 transgenic mice and after experimental brain lesion in rat: evidence for an induction by amyloid pathology. Brain Res. 2001 Sep 14;913(1):57-67.

Poduslo SE, Yin X. Chromosome 12 and late-onset Alzheimer's disease. Neurosci Lett. 2001 Sep 14;310(2-3):188-90.

Kim SH, Lubec G. Brain alpha-endosulfine is manifold decreased in brains from patients with Alzheimer's disease: a tentative marker and drug target? Neurosci Lett. 2001 Sep 14;310(2-3):77-80.

Bitan G, Lomakin A, Teplow DB. Amyloid beta-protein oligomerization: prenucleation interactions revealed by photo-induced cross-linking of unmodified proteins. J Biol Chem. 2001 Sep 14;276(37):35176-84.

Brühlmann C, Ooms F, Carrupt PA, Testa B, Catto M, Leonetti F, Altomare C, Carotti A. Coumarins derivatives as dual inhibitors of acetylcholinesterase and monoamine oxidase. J Med Chem. 2001 Sep 13;44(19):3195-8.

de Leon MJ, Convit A, Wolf OT, Tarshish CY, DeSanti S, Rusinek H, Tsui W, Kandil E, Scherer AJ, Roche A, Imossi A, Thorn E, Bobinski M, Caraos C, Lesbre P, Schlyer D, Poirier J, Reisberg B, Fowler J. Prediction of cognitive decline in normal elderly subjects with 2-[(18)F]fluoro-2-deoxy-D-glucose/poitron-emission tomography (FDG/PET). Proc Natl Acad Sci U S A. 2001 Sep 11;98(19):10966-71.

    

Hartmann D. From Alzheimer's disease to skin tumors: the catenin connection. Proc Natl Acad Sci U S A. 2001 Sep 11;98(19):10522-3.

Ikeda M, Hokoishi K, Maki N, Nebu A, Tachibana N, Komori K, Shigenobu K, Fukuhara R, Tanabe H. Increased prevalence of vascular dementia in Japan: a community-based epidemiological study. Neurology. 2001 Sep 11;57(5):839-44.

Lai MK, Lai OF, Keene J, Esiri MM, Francis PT, Hope T, Chen CP. Psychosis of Alzheimer's disease is associated with elevated muscarinic M2 binding in the cortex. Neurology. 2001 Sep 11;57(5):805-11.

Du Y, Dodel R, Hampel H, Buerger K, Lin S, Eastwood B, Bales K, Gao F, Moeller HJ, Oertel W, Farlow M, Paul S. Reduced levels of amyloid beta-peptide antibody in Alzheimer disease. Neurology. 2001 Sep 11;57(5):801-5. ,

Xia X, Qian S, Soriano S, Wu Y, Fletcher AM, Wang XJ, Koo EH, Wu X, Zheng H. Loss of presenilin 1 is associated with enhanced beta-catenin signaling and skin tumorigenesis. Proc Natl Acad Sci U S A. 2001 Sep 11;98(19):10863-8.

Nakamura S, Murayama N, Noshita T, Annoura H, Ohno T. Progressive brain dysfunction following intracerebroventricular infusion of beta(1-42)-amyloid peptide. Brain Res. 2001 Sep 7;912(2):128-36.

Scheuermann S, Hambsch B, Hesse L, Stumm J, Schmidt C, Beher D, Bayer TA, Beyreuther K, Multhaup G. Homodimerization of amyloid precursor protein and its implication in the amyloidogenic pathway of Alzheimer's disease. J Biol Chem. 2001 Sep 7;276(36):33923-9.

Waschuk SA, Elton EA, Darabie AA, Fraser PE, McLaurin JA. Cellular membrane composition defines A beta-lipid interactions. J Biol Chem. 2001 Sep 7;276(36):33561-8.

Beach TG, Kuo YM, Schwab C, Walker DG, Roher AE. Reduction of cortical amyloid beta levels in guinea pig brain after systemic administration of physostigmine. Neurosci Lett. 2001 Sep 7;310(1):21-4.

Planel E, Yasutake K, Fujita SC, Ishiguro K. Inhibition of protein phosphatase 2A overrides tau protein kinase I/glycogen synthase kinase 3 beta and cyclin-dependent kinase 5 inhibition and results in tau hyperphosphorylation in the hippocampus of starved mouse. J Biol Chem. 2001 Sep 7;276(36):34298-306.

Cervantes S, Gonzàlez-Duarte R, Marfany G. Homodimerization of presenilin N-terminal fragments is affected by mutations linked to Alzheimer's disease. FEBS Lett. 2001 Sep 7;505(1):81-6.

Yan R, Munzner JB, Shuck ME, Bienkowski MJ. BACE2 functions as an alternative alpha-secretase in cells. J Biol Chem. 2001 Sep 7;276(36):34019-27.

Danbolt NC. Glutamate uptake. Prog Neurobiol. 2001 Sep;65(1):1-105.

Lam AG, Koppal T, Akama KT, Guo L, Craft JM, Samy B, Schavocky JP, Watterson DM, Van Eldik LJ. Mechanism of glial activation by S100B: involvement of the transcription factor NFkappaB. Neurobiol Aging. 2001 Sep-Oct;22(5):765-72.

Golob EJ, Miranda GG, Johnson JK, Starr A. Sensory cortical interactions in aging, mild cognitive impairment, and Alzheimer's disease. Neurobiol Aging. 2001 Sep-Oct;22(5):755-63.

Dickerson BC, Goncharova I, Sullivan MP, Forchetti C, Wilson RS, Bennett DA, Beckett LA, Detoledo-Morrell L. MRI-derived entorhinal and hippocampal atrophy in incipient and very mild Alzheimer's disease. Neurobiol Aging. 2001 Sep-Oct;22(5):747-54.

Scinto LF, Frosch M, Wu CK, Daffner KR, Gedi N, Geula C. Selective cell loss in Edinger-Westphal in asymptomatic elders and Alzheimer's patients. Neurobiol Aging. 2001 Sep-Oct;22(5):729-36.

Das P, Murphy MP, Younkin LH, Younkin SG, Golde TE. Reduced effectiveness of Abeta1-42 immunization in APP transgenic mice with significant amyloid deposition. Neurobiol Aging. 2001 Sep-Oct;22(5):721-7. ,

 

Esiri MM. Potential for HSV-1 vaccination to reduce risk of HSV-1 encephalitis and/or Alzheimer's disease? Neurobiol Aging. 2001 Sep-Oct;22(5):711-3; discussion 717-9.

Ball MJ, Mathews R, Steiner I, Hill JM, Wisner TW, Murdoch GH, Kohama S, Sexton G, Nagalla S. Latent HSV 1 virus in trigeminal ganglia: the optimal site for linking prevention of Alzheimer's disease to vaccination. Neurobiol Aging. 2001 Sep-Oct;22(5):705-9; discussion 717-9.

Lin WR, Jennings R, Smith TL, Wozniak MA, Itzhaki RF. Vaccination prevents latent HSV1 infection of mouse brain. Neurobiol Aging. 2001 Sep-Oct;22(5):699-703.

Retz W, Thome J, Durany N, Harsányi A, Retz-Junginger P, Kornhuber J, Riederer P, Rösler M. Potential genetic markers of sporadic Alzheimer's dementia. Psychiatr Genet. 2001 Sep;11(3):115-22. ,

Kasparová J, Lisá V, Tucek S, Dolezal V. Chronic exposure of NG108-15 cells to amyloid beta peptide (A beta(1-42)) abolishes calcium influx via N-type calcium channels. Neurochem Res. 2001 Sep;26(8-9):1079-84.

Schmitz G, Orsó E. Intracellular cholesterol and phospholipid trafficking: comparable mechanisms in macrophages and neuronal cells. Neurochem Res. 2001 Sep;26(8-9):1045-68.

Galoyan AA, Sarkissian JS, Kipriyan TK, Sarkissian EJ, Chavushyan EA, Sulkhanyan RM, Meliksetyan IB, Abrahamyan SS, Grigorian YKh , Avetisyan ZA, Otieva NA. Protective effect of a new hypothalamic peptide against cobra venom and trauma-induced neuronal injury. Neurochem Res. 2001 Sep;26(8-9):1023-38.

Korczyn AD. Dementia in Parkinson's disease. J Neurol. 2001 Sep;248 Suppl 3:III1-4.

López Ibor M, Arrazola García J, Fernández Lucas A, Ortiz Alonso T, Maestú F, Martínez Castillo E. [Atrophy of the amygdala complex and neuropsychiatric expression of Alzheimer s disease] Rev Neurol. 2001 Sep 1;33(5):477-82.

Tabet N, Mantle D, Walker Z, Orrell M. Vitamins, trace elements, and antioxidant status in dementia disorders. Int Psychogeriatr. 2001 Sep;13(3):265-75.

Bschor T, Kühl KP, Reischies FM. Spontaneous speech of patients with dementia of the Alzheimer type and mild cognitive impairment. Int Psychogeriatr. 2001 Sep;13(3):289-98.

Kockler M, Heun R. The factor structure in the cognitive battery of the structured interview for the diagnosis of dementia of the Alzheimer type, multi-infarct dementia, and dementias of other aetiology. Int Psychogeriatr. 2001 Sep;13(3):311-23.

O'Brien JA, Caro JJ. Alzheimer's disease and other dementia in nursing homes: levels of management and cost. Int Psychogeriatr. 2001 Sep;13(3):347-58.

Curtis D, North BV, Sham PC. A novel method of two-locus linkage analysis applied to a genome scan for late onset Alzheimer's disease. Ann Hum Genet. 2001 Sep;65(Pt 5):473-81.

Parra D, González A, Mugueta C, Martínez A, Monreal I. Laboratory approach to mitochondrial diseases. J Physiol Biochem. 2001 Sep;57(3):267-84.

Frederickson CJ, Bush AI. Synaptically released zinc: physiological functions and pathological effects. Biometals. 2001 Sep-Dec;14(3-4):353-66.

Gibson SJ, Voukelatos X, Ames D, Flicker L, Helme RD. An examination of pain perception and cerebral event-related potentials following carbon dioxide laser stimulation in patients with Alzheimer's disease and age-matched control volunteers. Pain Res Manag. 2001 Fall;6(3):126-32.

Frenkel D, Solomon B. Towards Alzheimer's beta-amyloid vaccination. Biologicals. 2001 Sep-Dec;29(3-4):243-7.

Golebiowski M, Styczynska M, Pfeffer A, Barcikowska M, Cieszanowski A. [Interaction evaluation between APOE epsilon 4 alleles and hippocampal atrophy. Preliminary communication] Neurol Neurochir Pol. 2001 Sep-Oct;35(5):815-20.

Janus C, Phinney AL, Chishti MA, Westaway D. New developments in animal models of Alzheimer's disease. Curr Neurol Neurosci Rep. 2001 Sep;1(5):451-7.

Bertram L, Tanzi RE. Of replications and refutations: the status of Alzheimer's disease genetic research. Curr Neurol Neurosci Rep. 2001 Sep 1;1(5):442-50.

Knopman D. Pharmacotheraphy for Alzheimer's disease. Curr Neurol Neurosci Rep. 2001 Sep;1(5):428-34.

Xia W. Amyloid metabolism and secretases in Alzheimer's disease. Curr Neurol Neurosci Rep. 2001 Sep;1(5):422-7.

Burke W, Pinsky LE, Press NA. Categorizing genetic tests to identify their ethical, legal, and social implications. Am J Med Genet. 2001 Fall;106(3):233-40.

Kuo YM, Beach TG, Sue LI, Scott S, Layne KJ, Kokjohn TA, Kalback WM, Luehrs DC, Vishnivetskaya TA, Abramowski D, Sturchler-Pierrat C, Staufenbiel M, Weller RO, Roher AE. The evolution of A beta peptide burden in the APP23 transgenic mice: implications for A beta deposition in Alzheimer disease. Mol Med. 2001 Sep 1;7(9):609-18.

Cras P. Recent developments in Alzheimer's disease. Acta Clin Belg. 2001 Sep-Oct;56(5):269-78.

Chantoin S, Hazif-Thomas C, Billon R, Thomas P. [Development of a scale for assessing lack of motivation in elderly persons] Encephale. 2001 Sep-Oct;27(5):450-8.

Rasgon N, Jarvik GP, Jarvik L. Affective disorders and Alzheimer disease: a missing-link hypothesis. Am J Geriatr Psychiatry. 2001 Fall;9(4):444-5.

Olin JT, Fox LS, Pawluczyk S, Taggart NA, Schneider LS. A pilot randomized trial of carbamazepine for behavioral symptoms in treatment-resistant outpatients with Alzheimer disease. Am J Geriatr Psychiatry. 2001 Fall;9(4):400-5.

Schneider LS, Tariot PN, Lyketsos CG, Dagerman KS, Davis KL, Davis S, Hsiao JK, Jeste DV, Katz IR, Olin JT, Pollock BG, Rabins PV, Rosenheck RA, Small GW, Lebowitz B, Lieberman JA. National Institute of Mental Health Clinical Antipsychotic Trials of Intervention Effectiveness (CATIE): Alzheimer disease trial methodology. Am J Geriatr Psychiatry. 2001 Fall;9(4):346-60.

Laughren T. A regulatory perspective on psychiatric syndromes in Alzheimer disease. Am J Geriatr Psychiatry. 2001 Fall;9(4):340-5.

Schröder B, Franz B, Hempfling P, Selbert M, Jürgens T, Kretzschmar HA, Bodemer M, Poser S, Zerr I. Polymorphisms within the prion-like protein gene (Prnd) and their implications in human prion diseases, Alzheimer's disease and other neurological disorders. Hum Genet. 2001 Sep;109(3):319-25. ,

Morgan K, Licastro F, Tilley L, Ritchie A, Morgan L, Pedrini S, Kalsheker N. Polymorphism in the alpha(1)-antichymotrypsin (ACT) gene promoter: effect on expression in transfected glial and liver cell lines and plasma ACT concentrations. Hum Genet. 2001 Sep;109(3):303-10.

Ventura M, Sternon J. [Anticholinesterase agents in Alzheimer's disease] Rev Med Brux. 2001 Sep;22(4):A387-93.

Lin YM, Raffen R, Zhou Y, Cassidy CS, Flavin MT, Stevens FJ. Amyloid fibril formation in microwell plates for screening of inhibitors. Amyloid. 2001 Sep;8(3):182-93.

Poorkaj P, Kas A, D'Souza I, Zhou Y, Pham Q, Stone M, Olson MV, Schellenberg GD. A genomic sequence analysis of the mouse and human microtubule-associated protein tau. Mamm Genome. 2001 Sep;12(9):700-12.

Thames D. Alzheimer disease and alternative approaches to care a clinical snapshot. Geriatr Nurs. 2001 Sep-Oct;22(5):270.

Kanamori M, Suzuki M, Yamamoto K, Kanda M, Matsui Y, Kozima E, Takeuchi S, Oshiro H. [Evaluation of animal-assisted therapy for the elderly with senile dementia in a day care program] Nippon Ronen Igakkai Zasshi. 2001 Sep;38(5):659-64.

Yanagisawa K. [Molecular pathogenesis of Alzheimer's disease] Nippon Ronen Igakkai Zasshi. 2001 Sep;38(5):617-8.

Gerdner LA, Beck CK. Statewide survey to compare services provided for residents with dementia in special care units and non-special-care units. Am J Alzheimers Dis Other Demen. 2001 Sep-Oct;16(5):289-95.

Marks L, Flannery RB, Spillane M. Placement challenges: implications for long-term care of dementia sufferers. Am J Alzheimers Dis Other Demen. 2001 Sep-Oct;16(5):285-8.

Cox C, Albisu K. The Alzheimer's Connections Demonstration Program: instituting a national case management program. Am J Alzheimers Dis Other Demen. 2001 Sep-Oct;16(5):279-84.

Watanabe N, Tabira T. [Development of transgenic animal models for Alzheimer's disease] No To Shinkei. 2001 Sep;53(9):809-20.

Bertolucci PH, Okamoto IH, Brucki SM, Siviero MO, Toniolo Neto J, Ramos LR. Applicability of the CERAD neuropsychological battery to Brazilian elderly. Arq Neuropsiquiatr. 2001 Sep;59(3-A):532-6.

Heneka MT, Wiesinger H, Dumitrescu-Ozimek L, Riederer P, Feinstein DL, Klockgether T. Neuronal and glial coexpression of argininosuccinate synthetase and inducible nitric oxide synthase in Alzheimer disease. J Neuropathol Exp Neurol. 2001 Sep;60(9):906-16.

Roth KA. Caspases, apoptosis, and Alzheimer disease: causation, correlation, and confusion. J Neuropathol Exp Neurol. 2001 Sep 1;60(9):829-38.

Lack B, Daya S, Nyokong T. Interaction of serotonin and melatonin with sodium, potassium, calcium, lithium and aluminium. J Pineal Res. 2001 Sep;31(2):102-8.

Moretti R, Torre P, Antonello RM, Cazzato G. Gabapentin as a possible treatment of behavioral alterations in Alzheimer disease (AD) patients. Eur J Neurol. 2001 Sep;8(5):501-2.

Reid RT, Sabbagh MN, Thal LJ. Does apolipoprotein E (Apo-E) genotype influence nicotinic receptor binding in Alzheimer's disease. J Neural Transm. 2001 Sep;108(8-9):1043-50.

Heo HJ, Cho HY, Hong B, Kim HK, Kim EK, Kim BG, Shin DH. Protective effect of 4',5-dihydroxy-3',6,7-trimethoxyflavone from Artemisia asiatica against Abeta-induced oxidative stress in PC12 cells. Amyloid. 2001 Sep;8(3):194-201.

Deng A, Irizarry MC, Nitsch RM, Growdon JH, Rebeck GW. Elevation of cystatin C in susceptible neurons in Alzheimer's disease. Am J Pathol. 2001 Sep;159(3):1061-8.

Schmidt ML, Schuck T, Sheridan S, Kung MP, Kung H, Zhuang ZP, Bergeron C, Lamarche JS, Skovronsky D, Giasson BI, Lee VM, Trojanowski JQ. The fluorescent Congo red derivative, (trans, trans)-1-bromo-2,5-bis-(3-hydroxycarbonyl-4-hydroxy)styrylbenzene (BSB), labels diverse beta-pleated sheet structures in postmortem human neurodegenerative disease brains. Am J Pathol. 2001 Sep;159(3):937-43.

Goldsmith HS. Role of the omentum in the treatment of Alzheimer's disease. Neurol Res. 2001 Sep;23(6):555-64.

 

Cupers P, Orlans I, Craessaerts K, Annaert W, De Strooper B. The amyloid precursor protein (APP)-cytoplasmic fragment generated by gamma-secretase is rapidly degraded but distributes partially in a nuclear fraction of neurones in culture. J Neurochem. 2001 Sep;78(5):1168-78.

 

Dumanchin-Njock C, Alves da Costa CA, Mercken L, Pradier L, Checler F. The caspase-derived C-terminal fragment of betaAPP induces caspase-independent toxicity and triggers selective increase of Abeta42 in mammalian cells. J Neurochem. 2001 Sep;78(5):1153-61.

Martín D, Salinas M, López-Valdaliso R, Serrano E, Recuero M, Cuadrado A. Effect of the Alzheimer amyloid fragment Abeta(25-35) on Akt/PKB kinase and survival of PC12 cells. J Neurochem. 2001 Sep;78(5):1000-8.

Ruether E, Husmann R, Kinzler E, Diabl E, Klingler D, Spatt J, Ritter R, Schmidt R, Taneri Z, Winterer W, Koper D, Kasper S, Rainer M, Moessler H. A 28-week, double-blind, placebo-controlled study with Cerebrolysin in patients with mild to moderate Alzheimer's disease. Int Clin Psychopharmacol. 2001 Sep 1;16(5):253-63.

Isles A. A new function for Alzheimer's protein. Trends Genet. 2001 Sep;17(9):495.

Bruno V, Battaglia G, Copani A, D'Onofrio M, Di Iorio P, De Blasi A, Melchiorri D, Flor PJ, Nicoletti F. Metabotropic glutamate receptor subtypes as targets for neuroprotective drugs. J Cereb Blood Flow Metab. 2001 Sep;21(9):1013-33.

Meguro K, Shimada M, Yamaguchi S, Ishizaki J, Yamadori A, Sekita Y. A 5-year retrospective examination of cognitive screening test stages in normal older adults and patients with Alzheimer's disease: the Tajiri project. J Gerontol B Psychol Sci Soc Sci. 2001 Sep;56(5):P314-8.

Neundorfer MM, McClendon MJ, Smyth KA, Stuckey JC, Strauss ME, Patterson MB. A longitudinal study of the relationship between levels of depression among persons with Alzheimer's disease and levels of depression among their family caregivers. J Gerontol B Psychol Sci Soc Sci. 2001 Sep;56(5):P301-13.

Gatz M, Svedberg P, Pedersen NL, Mortimer JA, Berg S, Johansson B. Education and the risk of Alzheimer's disease: findings from the study of dementia in Swedish twins. J Gerontol B Psychol Sci Soc Sci. 2001 Sep;56(5):P292-300.

Owens J. Milking nature for Alzheimer's treatment. Drug Discov Today. 2001 Sep 1;6(17):866-868.

Paganelli AR, Ocaña OH, Prat MI, Franco PG, López SL, Morelli L, Adamo AM, Riccomagno MM, Matsubara E, Shoji M, Affranchino JL, Castaño EM, Carrasco AE. The Alzheimer-related gene presenilin-1 facilitates sonic hedgehog expression in Xenopus primary neurogenesis. Mech Dev. 2001 Sep;107(1-2):119-31.

Kurt MA, Davies DC, Kidd M, Duff K, Rolph SC, Jennings KH, Howlett DR. Neurodegenerative changes associated with beta-amyloid deposition in the brains of mice carrying mutant amyloid precursor protein and mutant presenilin-1 transgenes. Exp Neurol. 2001 Sep;171(1):59-71.

Lue LF, Walker DG, Brachova L, Beach TG, Rogers J, Schmidt AM, Stern DM, Yan SD. Involvement of microglial receptor for advanced glycation endproducts (RAGE) in Alzheimer's disease: identification of a cellular activation mechanism. Exp Neurol. 2001 Sep;171(1):29-45.

Cinar HN, Sweet KL, Hosemann KE, Earley K, Newman AP. The SEL-12 presenilin mediates induction of the Caenorhabditis elegans uterine pi cell fate. Dev Biol. 2001 Sep 1;237(1):173-82.

Chae HS, Bach JH, Lee MW, Kim HS, Kim YS, Kim KY, Choo KY, Choi SH, Park CH, Lee SH, Suh YH, Kim SS, Lee WB. Estrogen attenuates cell death induced by carboxy-terminal fragment of amyloid precursor protein in PC12 through a receptor-dependent pathway. J Neurosci Res. 2001 Sep 1;65(5):403-7.

Jhamandas JH, Cho C, Jassar B, Harris K, MacTavish D, Easaw J. Cellular mechanisms for amyloid beta-protein activation of rat cholinergic basal forebrain neurons. J Neurophysiol. 2001 Sep;86(3):1312-20.

Mochizuki Y, Oishi M, Takasu T. Correlations between P300 components and regional cerebral blood flows. J Clin Neurosci. 2001 Sep;8(5):407-10.

Mayo W, Le Moal M, Abrous DN. Pregnenolone sulfate and aging of cognitive functions: behavioral, neurochemical, and morphological investigations. Horm Behav. 2001 Sep;40(2):215-7.

Riedel-Heller SG, Busse A, Aurich C, Matschinger H, Angermeyer MC. Incidence of dementia according to DSM-III-R and ICD-10: results of the Leipzig Longitudinal Study of the Aged (LEILA75+), Part 2. Br J Psychiatry. 2001 Sep;179:255-60.

Riedel-Heller SG, Busse A, Aurich C, Matschinger H, Angermeyer MC. Prevalence of dementia according to DSM-III-R and ICD-10: results of the Leipzig Longitudinal Study of the Aged (LEILA75+) Part 1. Br J Psychiatry. 2001 Sep;179:250-4.

Chang YT, Tsai SF, Wang WJ, Hong CJ, Huang CY, Wong CK. A study of apolipoproteins E and A-I in cutaneous amyloids. Br J Dermatol. 2001 Sep;145(3):422-7.

  

Nilsberth C, Westlind-Danielsson A, Eckman CB, Condron MM, Axelman K, Forsell C, Stenh C, Luthman J, Teplow DB, Younkin SG, Näslund J, Lannfelt L. The 'Arctic' APP mutation (E693G) causes Alzheimer's disease by enhanced Abeta protofibril formation. Nat Neurosci. 2001 Sep;4(9):887-93.

    

McGrath LT, McGleenon BM, Brennan S, McColl D, McILroy S, Passmore AP. Increased oxidative stress in Alzheimer's disease as assessed with 4-hydroxynonenal but not malondialdehyde. QJM. 2001 Sep;94(9):485-90. ,

Chandra RK. Effect of vitamin and trace-element supplementation on cognitive function in elderly subjects. Nutrition. 2001 Sep 1;17(9):709-12.

 

Raji MA, Brady SR. Mirtazapine for treatment of depression and comorbidities in Alzheimer disease. Ann Pharmacother. 2001 Sep;35(9):1024-7.

Tikka T, Usenius T, Tenhunen M, Keinänen R, Koistinaho J. Tetracycline derivatives and ceftriaxone, a cephalosporin antibiotic, protect neurons against apoptosis induced by ionizing radiation. J Neurochem. 2001 Sep;78(6):1409-14.

Maccioni RB, Muñoz JP, Barbeito L. The molecular bases of Alzheimer's disease and other neurodegenerative disorders. Arch Med Res. 2001 Sep-Oct;32(5):367-81.

Tsolaki M, Kokarida K, Iakovidou V, Stilopoulos E, Meimaris J, Kazis A. Extrapyramidal symptoms and signs in Alzheimer's disease: prevalence and correlation with the first symptom. Am J Alzheimers Dis Other Demen. 2001 Sep-Oct;16(5):268-78.

Ellis KA, Nathan PJ. The pharmacology of human working memory. Int J Neuropsychopharmacol. 2001 Sep;4(3):299-313.

Potkin SG, Anand R, Fleming K, Alva G, Keator D, Carreon D, Messina J, Wu JC, Hartman R, Fallon JH. Brain metabolic and clinical effects of rivastigmine in Alzheimer's disease. Int J Neuropsychopharmacol. 2001 Sep;4(3):223-30.

von Bernhardi R, Ramírez G, Matile H, Döbeli H. Immobilized amyloid precursor protein constructs: a tool for the in vitro screening of glial cell reactivity. Eur J Neurosci. 2001 Sep;14(6):946-56.

Puri BK, Ho KW, Singh I. Age of seizure onset in adults with Down's syndrome. Int J Clin Pract. 2001 Sep;55(7):442-4.

Tripathi M, Sheshadri S, Padma MV, Jain S, Meheshwari MC, Behari M. Serum cobalamin levels in dementias. Neurol India. 2001 Sep;49(3):284-6.

Marvanová M, Lakso M, Pirhonen J, Nawa H, Wong G, Castrén E. The neuroprotective agent memantine induces brain-derived neurotrophic factor and trkB receptor expression in rat brain. Mol Cell Neurosci. 2001 Sep;18(3):247-58.

Mathews D, Unwin DH. Quantitative cerebral blood flow imaging in a patient with the Heidenhain variant of Creutzfeldt-Jakob disease. Clin Nucl Med. 2001 Sep;26(9):770-3.

Jha A, Tabet N, Orrell M. To tell or not to tell-comparison of older patients' reaction to their diagnosis of dementia and depression. Int J Geriatr Psychiatry. 2001 Sep;16(9):879-85.

González-Gross M, Marcos A, Pietrzik K. Nutrition and cognitive impairment in the elderly. Br J Nutr. 2001 Sep;86(3):313-21.

Gordon M, Goldstein D. Alzheimer's disease. To tell or not to tell. Can Fam Physician. 2001 Sep;47:1803-6, 1809.

Hanyu H, Asano T, Kogure D, Abe S, Iwamoto T, Takasaki M. [Diagnosis of Alzheimer's disease using brain SPECT with three-dimensional stereotactic surface projections] Rinsho Shinkeigaku. 2001 Sep;41(9):582-7.

Frost S, Myers LB, Newman SP. Genetic screening for Alzheimer's disease: what factors predict intentions to take a test? Behav Med. 2001 Fall;27(3):101-9.

Castro A, Martinez A. Peripheral and dual binding site acetylcholinesterase inhibitors: implications in treatment of Alzheimer's disease. Mini Rev Med Chem. 2001 Sep;1(3):267-72.

Link CD. Transgenic invertebrate models of age-associated neurodegenerative diseases. Mech Ageing Dev. 2001 Sep;122(14):1639-49. Abstract

Fan P, Liu Y, Zhang Z, Liu B, Ge W, Ye S, Cheng Y, Chen J. [Serum apolipoprotein A I, B100 and E levels and apolipoprotein E polymorphism in patients with Alzheimer's disease and multiple infarction dementia in Chinese population] Hua Xi Yi Ke Da Xue Xue Bao. 2001 Sep;32(3):389-91.

Meneses A. Role of 5-HT(6) receptors in memory formation. Drug News Perspect. 2001 Sep;14(7):396-400.

Thorns V, Licastro F, Masliah E. Locally reduced levels of acidic FGF lead to decreased expression of 28-kda calbindin and contribute to the selective vulnerability of the neurons in the entorhinal cortex in Alzheimer's disease. Neuropathology. 2001 Sep;21(3):203-11.

Iritani S, Niizato K, Emson PC. Relationship of calbindin D28K-immunoreactive cells and neuropathological changes in the hippocampal formation of Alzheimer's disease. Neuropathology. 2001 Sep;21(3):162-7.

Tarkowski E, Liljeroth AM, Nilsson A , Minthon L, Blennow K. Decreased levels of intrathecal interleukin 1 receptor antagonist in Alzheimer's disease. Dement Geriatr Cogn Disord. 2001 Sep-Oct;12(5):314-7.

McCaddon A, Hudson P, Davies G, Hughes A, Williams JH, Wilkinson C. Homocysteine and cognitive decline in healthy elderly. Dement Geriatr Cogn Disord. 2001 Sep-Oct;12(5):309-13. ,

Nicosia F, Alberici A, Benussi L, Gasparini L, Ghidoni R, Mazzoli F, Zanetti O, Frisoni GB, Geroldi C, Binetti G. Analysis of alpha-2-macroglobulin-2 allele as a risk factor in Alzheimer's disease. Dement Geriatr Cogn Disord. 2001 Sep-Oct;12(5):305-8. ,

Liou YJ, Lai IC, Hong CJ, Liu HC, Liu TY, Tsai SJ. Association analysis of the partially duplicated alpha7 nicotinic acetylcholine receptor genetic variant and Alzheimer's disease. Dement Geriatr Cogn Disord. 2001 Sep-Oct;12(5):301-4. ,

Matsuda S, Yasukawa T, Homma Y, Ito Y, Niikura T, Hiraki T, Hirai S, Ohno S, Kita Y, Kawasumi M, Kouyama K, Yamamoto T, Kyriakis JM, Nishimoto I. c-Jun N-terminal kinase (JNK)-interacting protein-1b/islet-brain-1 scaffolds Alzheimer's amyloid precursor protein with JNK. J Neurosci. 2001 Sep 1;21(17):6597-607.

Snow DM, Mullins N, Hynds DL. Nervous system-derived chondroitin sulfate proteoglycans regulate growth cone morphology and inhibit neurite outgrowth: a light, epifluorescence, and electron microscopy study. Microsc Res Tech. 2001 Sep 1;54(5):273-86.

Kapaki E, Kilidireas K, Paraskevas GP, Michalopoulou M, Patsouris E. Highly increased CSF tau protein and decreased beta-amyloid (1-42) in sporadic CJD: a discrimination from Alzheimer's disease? J Neurol Neurosurg Psychiatry. 2001 Sep;71(3):401-3. ,

 

Meguro K, LeMestric C, Landeau B, Desgranges B, Eustache F, Baron JC. Relations between hypometabolism in the posterior association neocortex and hippocampal atrophy in Alzheimer's disease: a PET/MRI correlative study. J Neurol Neurosurg Psychiatry. 2001 Sep;71(3):315-21.

Helmer C, Letenneur L, Rouch I, Richard-Harston S, Barberger-Gateau P, Fabrigoule C, Orgogozo JM, Dartigues JF. Occupation during life and risk of dementia in French elderly community residents. J Neurol Neurosurg Psychiatry. 2001 Sep;71(3):303-9.

Waite LM, Broe GA, Grayson DA, Creasey H. Preclinical syndromes predict dementia: the Sydney older persons study. J Neurol Neurosurg Psychiatry. 2001 Sep;71(3):296-302.

Pallitto MM, Murphy RM. A mathematical model of the kinetics of beta-amyloid fibril growth from the denatured state. Biophys J. 2001 Sep;81(3):1805-22.

Tilgner J, Volk B, Kaltschmidt C. Continuous interleukin-6 application in vivo via macroencapsulation of interleukin-6-expressing COS-7 cells induces massive gliosis. Glia. 2001 Sep;35(3):234-45.

McKenna DJ, Jones K, Hughes K. Efficacy, safety, and use of ginkgo biloba in clinical and preclinical applications. Altern Ther Health Med. 2001 Sep-Oct;7(5):70-86, 88-90.

Whitwell JL, Crum WR, Watt HC, Fox NC. Normalization of cerebral volumes by use of intracranial volume: implications for longitudinal quantitative MR imaging. AJNR Am J Neuroradiol. 2001 Sep;22(8):1483-9.

Brummel-Smith K. How much does it really cost to care for persons with Alzheimer's disease? J Am Geriatr Soc. 2001 Sep;49(9):1255-6.

McCormick WC, Hardy J, Kukull WA, Bowen JD, Teri L, Zitzer S, Larson EB. Healthcare utilization and costs in managed care patients with Alzheimer's disease during the last few years of life. J Am Geriatr Soc. 2001 Sep;49(9):1156-60.

Neumann PJ, Hammitt JK, Mueller C, Fillit HM, Hill J, Tetteh NA, Kosik KS. Public attitudes about genetic testing for Alzheimer's disease. Health Aff (Millwood). 2001 Sep-Oct;20(5):252-64.

Klein RC, Castellino FJ. Activators and inhibitors of the ion channel of the NMDA receptor. Curr Drug Targets. 2001 Sep;2(3):323-9.

Castellano C, Cestari V, Ciamei A. NMDA receptors and learning and memory processes. Curr Drug Targets. 2001 Sep;2(3):273-83.

Collins S, McLean CA, Masters CL. Gerstmann-Sträussler-Scheinker syndrome,fatal familial insomnia, and kuru: a review of these less common human transmissible spongiform encephalopathies. J Clin Neurosci. 2001 Sep;8(5):387-97.

Bien CG, Helmstaedter C, Elger CE. Is it really Alzheimer's disease? J Neurol Neurosurg Psychiatry. 2001 Sep;71(3):416-7.

Serby MJ. Olfactory deficit in Alzheimer's disease? Am J Psychiatry. 2001 Sep;158(9):1534; discussion 1534-5.

Nagy E, Loveland KA. Olfactory deficit in Alzheimer's disease? Am J Psychiatry. 2001 Sep;158(9):1533; discussion 1534-5.

Doty RL. Olfactory deficit in Alzheimer's disease? Am J Psychiatry. 2001 Sep;158(9):1533-4;

Friedman JI, Harvey PD, Coleman T, Moriarty PJ, Bowie C, Parrella M, White L, Adler D, Davis KL. Six-year follow-up study of cognitive and functional status across the lifespan in schizophrenia: a comparison with Alzheimer's disease and normal aging. Am J Psychiatry. 2001 Sep;158(9):1441-8.

Dracheva S, Marras SA, Elhakem SL, Kramer FR, Davis KL, Haroutunian V. N-methyl-D-aspartic acid receptor expression in the dorsolateral prefrontal cortex of elderly patients with schizophrenia. Am J Psychiatry. 2001 Sep;158(9):1400-10.

Gurwitz D. Immunization for Alzheimer's disease: yet closer to clinical trials. Trends Mol Med. 2001 Sep;7(9):385.

Carlson MC, Brandt J, Steele C, Baker A, Stern Y, Lyketsos CG. Predictor index of mortality in dementia patients upon entry into long-term care. J Gerontol A Biol Sci Med Sci. 2001 Sep;56(9):M567-70.

Shanks MF, Pestell SJ, Venneri A, Taylor L, Porter RW. Anthropometric risk factors in Alzheimer's disease. Int J Geriatr Psychiatry. 2001 Sep;16(9):918-9.

Caligiuri MP, Peavy G, Galasko DR. Extrapyramidal signs and cognitive abilities in Alzheimer's disease. Int J Geriatr Psychiatry. 2001 Sep;16(9):907-11.

Tractenberg RE, Gamst A, Weiner MF, Koss E, Thomas RG, Teri L, Thal L. Frequency of behavioral symptoms characterizes agitation in Alzheimer's disease. Int J Geriatr Psychiatry. 2001 Sep;16(9):886-91.

Eustace A, Kidd N, Greene E, Fallon C, Bhrain SN, Cunningham C, Coen R, Walsh JB, Coakley D, Lawlor BA. Verbal aggression in Alzheimer's disease. Clinical, functional and neuropsychological correlates. Int J Geriatr Psychiatry. 2001 Sep;16(9):858-61.

Wilkinson D, Murray J. Galantamine: a randomized, double-blind, dose comparison in patients with Alzheimer's disease. Int J Geriatr Psychiatry. 2001 Sep;16(9):852-7.

Small BJ, Fratiglioni L, Bäckman L. Canaries in a coal mine: cognitive markers of preclinical Alzheimer disease. Arch Gen Psychiatry. 2001 Sep;58(9):859-60.

 

Chen P, Ratcliff G, Belle SH, Cauley JA, DeKosky ST, Ganguli M. Patterns of cognitive decline in presymptomatic Alzheimer disease: a prospective community study. Arch Gen Psychiatry. 2001 Sep;58(9):853-8.

 

Hsu YY, Du AT, Schuff N, Weiner MW. Magnetic resonance imaging and magnetic resonance spectroscopy in dementias. J Geriatr Psychiatry Neurol. 2001 Fall;14(3):145-66.

Gallagher-Thompson D, O'Hara R, Simmons A, Kraemer HC, Murphy GM. Apolipoprotein E epsilon4 allele affects the relationship between stress and depression in caregivers of patients with Alzheimer's disease. J Geriatr Psychiatry Neurol. 2001 Fall;14(3):115-9.

Gottfries J, Blennow K, Lehmann MW, Regland B, Gottfries CG. One-carbon metabolism and other biochemical correlates of cognitive impairment as visualized by principal component analysis. J Geriatr Psychiatry Neurol. 2001 Fall;14(3):109-14.