Dementia-Alzheimer’s Research Papers ~ July 2000

Dementia-Alzheimer’s Research Papers ~ July 2000     

           

Kantarci K, Jack CR, Xu YC, Campeau NG, O'Brien PC, Smith GE, Ivnik RJ, Boeve BF, Kokmen E, Tangalos EG, Petersen RC. Regional metabolic patterns in mild cognitive impairment and Alzheimer's disease: A 1H MRS study. Neurology. 2000 Jul 25;55(2):210-7.

Nath R, Davis M, Probert AW, Kupina NC, Ren X, Schielke GP, Wang KK. Processing of cdk5 activator p35 to its truncated form (p25) by calpain in acutely injured neuronal cells. Biochem Biophys Res Commun. 2000 Jul 21;274(1):16-21.

Marx J. ALZHEIMER'S CONGRESS: Drug Shows Promise for Advanced Disease. Science. 2000 Jul 21;289(5478):375b-377b.

Helmuth L. ALZHEIMER'S CONGRESS: Further Progress on a. Science. 2000 Jul 21;289(5478):375a.

Raina AK, Zhu X, Rottkamp CA, Monteiro M, Takeda A, Smith MA. Cyclin' toward dementia: cell cycle abnormalities and abortive oncogenesis in Alzheimer disease. J Neurosci Res. 2000 Jul 15;61(2):128-33.

  

Haniu M, Denis P, Young Y, Mendiaz EA, Fuller J, Hui JO, Bennett BD, Kahn S, Ross S, Burgess T, Katta V, Rogers G, Vassar R, Citron M. Characterization of Alzheimer's beta -secretase protein BACE. A pepsin family member with unusual properties. J Biol Chem. 2000 Jul 14;275(28):21099-106.

Bennett BD, Babu-Khan S, Loeloff R, Louis JC, Curran E, Citron M, Vassar R. Expression analysis of BACE2 in brain and peripheral tissues. J Biol Chem. 2000 Jul 7;275(27):20647-51.

Heese K, Nagai Y, Sawada T. Induction of rat L-phosphoserine phosphatase by amyloid-beta (1-42) is inhibited by interleukin-11. Neurosci Lett. 2000 Jul 7;288(1):37-40.

Bhojak TJ, DeKosky ST, Ganguli M, Kamboh MI. Genetic polymorphisms in the cathespin D and interleukin-6 genes and the risk of Alzheimer's disease. Neurosci Lett. 2000 Jul 7;288(1):21-4. ,

Fitzjohn SM, Morton RA, Kuenzi F, Davies CH, Seabrook GR, Collingridge GL. Similar levels of long-term potentiation in amyloid precursor protein -null and wild-type mice in the CA1 region of picrotoxin treated slices. Neurosci Lett. 2000 Jul 7;288(1):9-12.

Moalem S, Percy ME, Andrews DF, Kruck TP, Wong S, Dalton AJ, Mehta P, Fedor B, Warren AC. Are hereditary hemochromatosis mutations involved in Alzheimer disease? Am J Med Genet. 2000 Jul 3;93(1):58-66. ,

Merrill DA, Roberts JA, Tuszynski MH. Conservation of neuron number and size in entorhinal cortex layers II, III, and V/VI of aged primates. J Comp Neurol. 2000 Jul 3;422(3):396-401.

Beal MF. Energetics in the pathogenesis of neurodegenerative diseases. Trends Neurosci. 2000 Jul;23(7):298-304.

  

Keller JN, Hanni KB, Markesbery WR. Impaired proteasome function in Alzheimer's disease. J Neurochem. 2000 Jul;75(1):436-9.

Guo Z, Ersoz A, Butterfield DA, Mattson MP. Beneficial effects of dietary restriction on cerebral cortical synaptic terminals: preservation of glucose and glutamate transport and mitochondrial function after exposure to amyloid beta-peptide, iron, and 3-nitropropionic acid. J Neurochem. 2000 Jul;75(1):314-20.

Zhu H, Fu W, Mattson MP. The catalytic subunit of telomerase protects neurons against amyloid beta-peptide-induced apoptosis. J Neurochem. 2000 Jul;75(1):117-24.

Kashiwa A, Yoshida H, Lee S, Paladino T, Liu Y, Chen Q, Dargusch R, Schubert D, Kimura H. Isolation and characterization of novel presenilin binding protein. J Neurochem. 2000 Jul;75(1):109-16.

 

Mbella EG, Bertrand S, Huez G, Octave JN. A GG nucleotide sequence of the 3' untranslated region of amyloid precursor protein mRNA plays a key role in the regulation of translation and the binding of proteins. Mol Cell Biol. 2000 Jul;20(13):4572-9.

Schwemmer M, Fink B, Köckerbauer R, Bassenge E. How urine analysis reflects oxidative stress--nitrotyrosine as a potential marker. Clin Chim Acta. 2000 Jul;297(1-2):207-16.

Zhu X, Raina AK, Boux H, Simmons ZL, Takeda A, Smith MA. Activation of oncogenic pathways in degenerating neurons in Alzheimer disease. Int J Dev Neurosci. 2000 Jul-Aug;18(4-5):433-7.

Mehlhorn G, Hollborn M, Schliebs R. Induction of cytokines in glial cells surrounding cortical beta-amyloid plaques in transgenic Tg2576 mice with Alzheimer pathology. Int J Dev Neurosci. 2000 Jul-Aug;18(4-5):423-31.

Perry G, Nunomura A, Hirai K, Takeda A, Aliev G, Smith MA. Oxidative damage in Alzheimer's disease: the metabolic dimension. Int J Dev Neurosci. 2000 Jul-Aug;18(4-5):417-21.

Youdim KA, Martin A, Joseph JA. Essential fatty acids and the brain: possible health implications. Int J Dev Neurosci. 2000 Jul-Aug;18(4-5):383-99.

Green PS, Simpkins JW. Neuroprotective effects of estrogens: potential mechanisms of action. Int J Dev Neurosci. 2000 Jul-Aug;18(4-5):347-58.

Frenkel D, Solomon B, Benhar I. Modulation of Alzheimer's beta-amyloid neurotoxicity by site-directed single-chain antibody. J Neuroimmunol. 2000 Jul 1;106(1-2):23-31.

Lowery K, Mynt P, Aisbett J, Dixon T, O'Brien J, Ballard C. Depression in the carers of dementia sufferers: a comparison of the carers of patients suffering from dementia with Lewy bodies and the carers of patients with Alzheimer's disease. J Affect Disord. 2000 Jul;59(1):61-5.

Koshimura K, Murakami Y, Tanaka J, Kato Y. The role of 6R-tetrahydrobiopterin in the nervous system. Prog Neurobiol. 2000 Jul;61(4):415-38.

Hu J, Wang Q, Liang W. [Effects of bushen yizhi recipe on somatostatin-like immunopositive and somatostatin messenger ribonucleic acid expressed-positive neurons in Alzheimer's disease model rats] Zhongguo Zhong Xi Yi Jie He Za Zhi. 2000 Jul;20(7):533-5.

DeFeudis FV, Drieu K. Ginkgo biloba extract (EGb 761) and CNS functions: basic studies and clinical applications. Curr Drug Targets. 2000 Jul;1(1):25-58.

Cummings JL. The role of cholinergic agents in the management of behavioural disturbances in Alzheimer's disease. Int J Neuropsychopharmacol. 2000 Jul;3(7):21-29.

Knopman DS. Management of cognition and function: new results from the clinical trials programme of Aricept(R) (donepezil HCl). Int J Neuropsychopharmacol. 2000 Jul;3(7):13-20.

Sian AK, Frears ER, El-Agnaf OM, Patel BP, Manca MF, Siligardi G, Hussain R, Austen BM. Oligomerization of beta-amyloid of the Alzheimer's and the Dutch-cerebral-haemorrhage types. Biochem J. 2000 Jul 1;349(Pt 1):299-308.

Baumann MH, Kallijärvi J, Lankinen H, Soto C, Haltia M. Apolipoprotein E includes a binding site which is recognized by several amyloidogenic polypeptides. Biochem J. 2000 Jul 1;349(Pt 1):77-84.

Torrey EF, Miller J, Rawlings R, Yolken RH. Seasonal birth patterns of neurological disorders. Neuroepidemiology. 2000 Jul-Aug;19(4):177-85.

DiCiero Miranda M, de Bruin VM, Vale MR, Viana GS. Lipid peroxidation and nitrite plus nitrate levels in brain tissue from patients with Alzheimer's disease. Gerontology. 2000 Jul-Aug;46(4):179-84.

Vidal R, Calero M, Piccardo P, Farlow MR, Unverzagt FW, Méndez E, Jiménez-Huete A, Beavis R, Gallo G, Gomez-Tortosa E, Ghiso J, Hyman BT, Frangione B, Ghetti B. Senile dementia associated with amyloid beta protein angiopathy and tau perivascular pathology but not neuritic plaques in patients homozygous for the APOE-epsilon4 allele. Acta Neuropathol. 2000 Jul;100(1):1-12.

Le Bars PL, Kieser M, Itil KZ. A 26-week analysis of a double-blind, placebo-controlled trial of the ginkgo biloba extract EGb 761 in dementia. Dement Geriatr Cogn Disord. 2000 Jul-Aug;11(4):230-7.

Marra C, Silveri MC, Gainotti G. Predictors of cognitive decline in the early stage of probable Alzheimer's disease. Dement Geriatr Cogn Disord. 2000 Jul-Aug;11(4):212-8.

McGleenon BM, Passmore AP, McAuley DF, Johnston GD. No evidence of endothelial dysfunction in patients with Alzheimer's disease. Dement Geriatr Cogn Disord. 2000 Jul-Aug;11(4):197-201.

Armstrong RA, Cairns NJ, Lantos PL. Beta-amyloid deposition in the temporal lobe of patients with dementia with Lewy bodies: comparison with non-demented cases and Alzheimer's disease. Dement Geriatr Cogn Disord. 2000 Jul-Aug;11(4):187-92.

Eckert GP, Cairns NJ, Maras A, Gattaz WF, Müller WE. Cholesterol modulates the membrane-disordering effects of beta-amyloid peptides in the hippocampus: specific changes in Alzheimer's disease. Dement Geriatr Cogn Disord. 2000 Jul-Aug;11(4):181-6.

 

Loske C, Gerdemann A, Schepl W, Wycislo M, Schinzel R, Palm D, Riederer P, Münch G. Transition metal-mediated glycoxidation accelerates cross-linking of beta-amyloid peptide. Eur J Biochem. 2000 Jul;267(13):4171-8.

  

Esler WP, Kimberly WT, Ostaszewski BL, Diehl TS, Moore CL, Tsai JY, Rahmati T, Xia W, Selkoe DJ, Wolfe MS. Transition-state analogue inhibitors of gamma-secretase bind directly to presenilin-1. Nat Cell Biol. 2000 Jul;2(7):428-34.

 

  

Takeuchi A, Irizarry MC, Duff K, Saido TC, Hsiao Ashe K, Hasegawa M, Mann DM, Hyman BT, Iwatsubo T. Age-related amyloid beta deposition in transgenic mice overexpressing both Alzheimer mutant presenilin 1 and amyloid beta precursor protein Swedish mutant is not associated with global neuronal loss. Am J Pathol. 2000 Jul;157(1):331-9. ,

  

Hamilton RL. Lewy bodies in Alzheimer's disease: a neuropathological review of 145 cases using alpha-synuclein immunohistochemistry. Brain Pathol. 2000 Jul;10(3):378-84.

Mega MS. The cholinergic deficit in Alzheimer's disease: impact on cognition, behaviour and function. Int J Neuropsychopharmacol. 2000 Jul;3(7):3-12.

Anderson AJ, Ruehl WW, Fleischmann LK, Stenstrom K, Entriken TL, Cummings BJ. DNA damage and apoptosis in the aged canine brain: relationship to Abeta deposition in the absence of neuritic pathology. Prog Neuropsychopharmacol Biol Psychiatry. 2000 Jul;24(5):787-99.

Kálmán J, Juhász A, Majtényi K, Rimanóczy A, Jakab K, Gárdián G, Raskó I, Janka Z. Apolipoprotein E polymorphism in Pick's disease and in Huntington's disease. Neurobiol Aging. 2000 Jul-Aug;21(4):555-8.

Kobayashi K, Shimoda K, Higashima M, Nakano H, Miyazu K, Hayashi M, Tabata O, Koshino Y. Report of three cases of Alzheimer's disease with focal motor symptoms: clinical correlates of neuroimaging findings. World J Biol Psychiatry. 2000 Jul;1(3):164-9.

  

Shimura H, Hattori N, Kubo S, Mizuno Y, Asakawa S, Minoshima S, Shimizu N, Iwai K, Chiba T, Tanaka K, Suzuki T. Familial Parkinson disease gene product, parkin, is a ubiquitin-protein ligase. Nat Genet. 2000 Jul 1;25(3):302-5.

 

Steffen KA, Carnes M. Hormone Replacement Therapy in Prevention of Morbidity and Mortality in the Older Woman. Part IV: HRT and the Aging Brain, Overall Mortality, and Individual Decision-Making. J Am Med Dir Assoc. 2000 Jul-Aug;1(4):164-71.

Cacabelos R, Alvarez A, Lombardi V, Fernandez-Novoa L, Corzo L, Perez P, Laredo M, Pichel V, Hernandez A, Varela M, Figueroa J, Prous J, Windisch M, Vigo C. Pharmacological treatment of Alzheimer disease: From psychotropic drugs and cholinesterase inhibitors to pharmacogenomics. Drugs Today (Barc). 2000 Jul;36(7):415-99.

  

Ginsberg SD, Hemby SE, Lee VM, Eberwine JH, Trojanowski JQ. Expression profile of transcripts in Alzheimer's disease tangle-bearing CA1 neurons. Ann Neurol. 2000 Jul;48(1):77-87.

Lee CK, Weindruch R, Prolla TA. Gene-expression profile of the ageing brain in mice. Nat Genet. 2000 Jul;25(3):294-7. ,

Rondeau V, Commenges D, Jacqmin-Gadda H, Dartigues JF. Relation between aluminum concentrations in drinking water and Alzheimer's disease: an 8-year follow-up study. Am J Epidemiol. 2000 Jul 1;152(1):59-66.

 

Pepeu G. Alzheimer Symposium. Etiopathogenetic mechanisms of Alzheimer's disease. IDrugs. 2000 Jul;3(7):742.

Small DH. Alzheimer Symposium. Gamma-secretase, presenilins and WNT proteins. IDrugs. 2000 Jul;3(7):740-1.

Herholz K. Advances in Alzheimer therapy. Neuroimaging and vascular dementia. IDrugs. 2000 Jul;3(7):737-9.

Mucke HA. Advances in Alzheimer therapy - sixth International Stockholm/Springfield Symposium. IDrugs. 2000 Jul;3(7):730-6.

Grodstein F, Chen J, Pollen DA, Albert MS, Wilson RS, Folstein MF, Evans DA, Stampfer MJ. Postmenopausal hormone therapy and cognitive function in healthy older women. J Am Geriatr Soc. 2000 Jul 1;48(7):746-52.

Lendon CL, Han BH, Salimi K, Fagan AM, Behrens MI, Muller MC, Holtzman DM. No effect of apolipoprotein E on neuronal cell death due to excitotoxic and apoptotic agents in vitro and neonatal hypoxic ischaemia in vivo. Eur J Neurosci. 2000 Jul;12(7):2235-42. ,

Maraganore DM, Farrer MJ, Hardy JA, McDonnell SK, Schaid DJ, Rocca WA. Case-control study of debrisoquine 4-hydroxylase, N-acetyltransferase 2, and apolipoprotein E gene polymorphisms in Parkinson's disease. Mov Disord. 2000 Jul;15(4):714-9.

Roberts JS, Connell CM. Illness representations among first-degree relatives of people with Alzheimer disease. Alzheimer Dis Assoc Disord. 2000 Jul-Sep;14(3):129-136,Discussion 127-8.

Overall KL. Natural animal models of human psychiatric conditions: assessment of mechanism and validity. Prog Neuropsychopharmacol Biol Psychiatry. 2000 Jul;24(5):727-76.

Yagi Y, Tomita S, Nakamura M, Suzuki T. Overexpression of human amyloid precursor protein in Drosophila. Mol Cell Biol Res Commun. 2000 Jul;4(1):43-9.

Chu LW, Chiu KC, Hui SL, Yu GK, Tsui WJ, Lee PW. The reliability and validity of the Alzheimer's Disease Assessment Scale Cognitive Subscale (ADAS-Cog) among the elderly Chinese in Hong Kong. Ann Acad Med Singapore. 2000 Jul;29(4):474-85.

Tanaka S. [Gene diagnosis of Alzheimer's disease and related disorders] Rinsho Byori. 2000 Jul;48(7):621-4.

Sickmann A, Dormeyer W, Wortelkamp S, Woitalla D, Kuhn W, Meyer HE. Identification of proteins from human cerebrospinal fluid, separated by two-dimensional polyacrylamide gel electrophoresis. Electrophoresis. 2000 Jul;21(13):2721-8.

Emeriau JP, Lehert P, Mosnier M. Efficacy of naftidrofuryl in patients with vascular or mixed dementia: results of a multicenter, double-blind trial. Clin Ther. 2000 Jul;22(7):834-44.