Amyloid Precursor Protein ~ Precursor Protein Amyloid ~ Research papers on Amyloid Precursor Protein ~ Aug 2011 Cheng Y, Judd TC, Bartberger MD, Brown J, Chen K, Fremeau RT, Hickman D, Hitchcock SA, Jordan B, Li V, Lopez P, Louie SW, Luo Y, Michelsen K, Nixey T, Powers TS, Rattan C, Sickmier EA, St Jean DJ, Wahl RC, Wen PH, Wood S. From Fragment Screening to In Vivo Efficacy: Optimization of a Series of 2-Aminoquinolines as Potent Inhibitors of Beta-Site Amyloid Precursor Protein Cleaving Enzyme 1 (BACE1). J Med Chem. 2011 Aug 25;54(16):5836-57. Read Paper on Amyloid Precursor Protein Alexandrov PN, Pogue A, Bhattacharjee S, Lukiw WJ. Retinal amyloid peptides and complement factor H in transgenic models of Alzheimer's disease. Neuroreport. 2011 Aug 24;22(12):623-7. Read Paper on Amyloid Precursor Protein Fu R, Wang X, Li C, Santiago-Miranda AN, Pielak GJ, Tian F. In Situ Structural Characterization of a Recombinant Protein in Native Escherichia coli Membranes with Solid-State Magic-Angle-Spinning NMR. J Am Chem Soc. 2011 Aug 17;133(32):12370-3. Read Paper on Amyloid Precursor Protein Wang BR, Shi JQ, Zhang YD, Zhu DL, Shi JP. Angiotensin II does not directly affect Aß secretion or ß-/?-secretase activity via activation of angiotensin II type 1 receptor. Neurosci Lett. 2011 Aug 15;500(2):103-7.Read Paper on Amyloid Precursor Protein Shi X, Lu X, Zhan L, Liu L, Sun M, Gong X, Sui H, Niu X, Liu S, Zheng L, Chen J, Zhou Y. Rat hippocampal proteomic alterations following intrahippocampal injection of amyloid beta peptide (1-40). Neurosci Lett. 2011 Aug 15;500(2):87-91. Read Paper on Amyloid Precursor Protein Cho JE, Kim JR. Recent Approaches Targeting Beta-Amyloid for Therapeutic Intervention of Alzheimer's Disease. Recent Pat CNS Drug Discov. 2011 Aug 12; Read Paper on Amyloid Precursor Protein Matsuda S, Tamayev R, D'Adamio L. Increased AßPP Processing in Familial Danish Dementia Patients. J Alzheimers Dis. 2011 Aug 12;Read Paper on Amyloid Precursor Protein Bauer C, Pardossi-Piquard R, Dunys J, Roy M, Checler F. ?-Secretase-Mediated Regulation of Neprilysin: Influence of Cell Density and Aging and Modulation by Imatinib. J Alzheimers Dis. 2011 Aug 12; Read Paper on Amyloid Precursor Protein Bi XH, Lu CM, Liu Q, Zhang ZX, Zhao HL, Yu J, Zhang JW. A 14 bp indel variation in the NCX1 gene modulates the age at onset in late-onset Alzheimer's disease. J Neural Transm. 2011 Aug 11; Read Paper on Amyloid Precursor Protein Zhi P, Chia C, Gleeson PA. Intracellular trafficking of the ß-secretase and processing of amyloid precursor protein. IUBMB Life. 2011 Aug 10;Read Paper on Amyloid Precursor Protein Domingues SC, Henriques AG, Fardilha M, da Cruz E Silva EF, da Cruz E Silva OA. Identification and characterization of a neuronal enriched novel transcript encoding the previously described p60Fe65 isoform. J Neurochem. 2011 Aug 9; Read Paper on Amyloid Precursor Protein Suh J, Lyckman A, Wang L, Eckman EA, Guénette SY. FE65 Proteins Regulate NMDA Receptor Activation-induced Amyloid Precursor Protein Processing. J Neurochem. 2011 Aug 9; Read Paper on Amyloid Precursor Protein Sannerud R, Declerck I, Peric A, Raemaekers T, Menendez G, Zhou L, Veerle B, Coen K, Munck S, De Strooper B, Schiavo G, Annaert W. ADP ribosylation factor 6 (ARF6) controls amyloid precursor protein (APP) processing by mediating the endosomal sorting of BACE1. Proc Natl Acad Sci U S A. 2011 Aug 8; Read Paper on Amyloid Precursor Protein Qiang L, Fujita R, Yamashita T, Angulo S, Rhinn H, Rhee D, Doege C, Chau L, Aubry L, Vanti WB, Moreno H, Abeliovich A. Directed conversion of Alzheimer's disease patient skin fibroblasts into functional neurons.Cell. 2011 Aug 5;146(3):359-71. Read Paper on Amyloid Precursor Protein Cheng F, Cappai R, Ciccotosto GD, Svensson G, Multhaup G, Fransson LÅ, Mani K. Suppression of Amyloid {beta} A11 Antibody Immunoreactivity by Vitamin C: POSSIBLE ROLE OF HEPARAN SULFATE OLIGOSACCHARIDES DERIVED FROM GLYPICAN-1 BY ASCORBATE-INDUCED, NITRIC OXIDE (NO)-CATALYZED DEGRADATION. J Biol Chem. 2011 Aug 5;286(31):27559-72. Read Paper on Amyloid Precursor Protein Jefferson T, Causevic M, Auf dem Keller U, Schilling O, Isbert S, Geyer R, Maier W, Tschickardt S, Jumpertz T, Weggen S, Bond JS, Overall CM, Pietrzik CU, Becker-Pauly C. Metalloprotease Meprin {beta} Generates Nontoxic N-terminal Amyloid Precursor Protein Fragments in Vivo. J Biol Chem. 2011 Aug 5;286(31):27741-50. Read Paper on Amyloid Precursor Protein Hashimoto T, Adams KW, Fan Z, McLean PJ, Hyman BT.Characterization of Oligomer Formation of Amyloid-{beta} Peptide Using a Split-luciferase Complementation Assay. J Biol Chem. 2011 Aug 5;286(31):27081-91. Read Paper on Amyloid Precursor Protein Miñano-Molina AJ, España J, Martín E, Barneda-Zahonero B, Fadó R, Solé M, Trullás R, Saura CA, Rodríguez-Alvarez J. Soluble Oligomers of Amyloid-{beta} Peptide Disrupt Membrane Trafficking of {alpha}-Amino-3-hydroxy-5-methylisoxazole-4-propionic Acid Receptor Contributing to Early Synapse Dysfunction. J Biol Chem. 2011 Aug 5;286(31):27311-21.Read Paper on Amyloid Precursor Protein Kim S, Rhim H. Effects of amyloid-ß peptides on voltage-gated L-type Ca(V)1.2 and Ca (V)1.3 Ca (2+) channels. Mol Cells. 2011 Aug 4; Read Paper on Amyloid Precursor Protein Rabe S, Reichwald J, Ammaturo D, De Strooper B, Saftig P, Neumann U, Staufenbiel M. The Swedish APP mutation alters the effect of genetically reduced BACE1 expression on the APP processing. J Neurochem. 2011 Aug 4; Read Paper on Amyloid Precursor Protein McMillan LE, Brown JT, Henley JM, Cimarosti H. Profiles of SUMO and ubiquitin conjugation in an Alzheimer's disease model. Neurosci Lett. 2011 Aug 4; Read Paper on Amyloid Precursor Protein Guo X, Wu X, Ren L, Liu G, Li L. Epigenetic mechanisms of amyloid-ß production in anisomycin-treated SH-SY5Y cells. Neuroscience. 2011 Aug 3; Read Paper on Amyloid Precursor Protein Hashimoto H, Takeuchi T, Komatsu K, Miyazaki K, Sato M, Higashi S.Structural basis for matrix metalloproteinase-2 (MMP-2)-selective inhibitory action of {beta}-amyloid precursor protein-derived inhibitor. J Biol Chem. 2011 Aug 3; Read Paper on Amyloid Precursor Protein Riera J, Hatanaka R, Uchida T, Ozaki T, Kawashima R. Quantifying the uncertainty of spontaneous ca(2+) oscillations in astrocytes: particulars of Alzheimer's disease. Biophys J. 2011 Aug 3;101(3):554-64. Read Paper on Amyloid Precursor Protein Schweinzer C, Kober A, Lang I, Etschmaier K, Scholler M, Kresse A, Sattler W, Panzenboeck U. Processing of Endogenous AßPP in Blood-Brain Barrier Endothelial Cells is Modulated by Liver-X Receptor Agonists and Altered Cellular Cholesterol Homeostasis. J Alzheimers Dis. 2011 Aug 2;Read Paper on Amyloid Precursor Protein |
Amyloid beta (Aβ or Abeta) is a peptide of 36–43 amino acids that is processed from the Amyloid precursor protein. While best known as a component of amyloid plaques in association with Alzheimer's disease, evidence has been found that Aβ is a highly multifunctional peptide with significant non-pathological activity.[1] Aβ is the main component of deposits found in the brains of patients with Alzheimer's disease
Amyloid Precursor Protein ~ Precursor Protein Amyloid ~ Research papers on Amyloid Precursor Protein ~ Aug 2011
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