Beta Amyloid Peptide: Alzheimer’s Research Papers~ November 2002 ~ Beta Amyloid Blog

Alzheimer’s Research Papers~ November 2002 ~ Beta Amyloid Blog


Alzheimer’s Research Papers~ November 2002 ~ Beta Amyloid Blog    


Lalonde R, Dumont M, Staufenbiel M, Sturchler-Pierrat C, Strazielle C. Spatial learning, exploration, anxiety, and motor coordination in female APP23 transgenic mice with the Swedish mutation. Brain Res. 2002 Nov 22;956(1):36-44.

Jo I, Im HM, Shin HJ, Won Cho K, Jung M, Kim SD, Kim Jeong J, Ahn Jo S. Serum deprivation increases the expression of low density lipoprotein receptor-related protein in primary cultured rat astrocytes. Biochem Biophys Res Commun. 2002 Nov 22;299(1):102-8.

Maynard CJ, Cappai R, Volitakis I, Cherny RA, White AR, Beyreuther K, Masters CL, Bush AI, Li QX. Overexpression of Alzheimer's disease amyloid-beta opposes the age-dependent elevations of brain copper and iron. J Biol Chem. 2002 Nov 22;277(47):44670-6.

Lammich S, Okochi M, Takeda M, Kaether C, Capell A, Zimmer AK, Edbauer D, Walter J, Steiner H, Haass C. Presenilin-dependent intramembrane proteolysis of CD44 leads to the liberation of its intracellular domain and the secretion of an Abeta-like peptide. J Biol Chem. 2002 Nov 22;277(47):44754-9.
 

Sterling J, Herzig Y, Goren T, Finkelstein N, Lerner D, Goldenberg W, Miskolczi I, Molnar S, Rantal F, Tamas T, Toth G, Zagyva A, Zekany A, Lavian G, Gross A, Friedman R, Razin M, Huang W, Krais B, Chorev M, Youdim MB, Weinstock M. Novel dual inhibitors of AChE and MAO derived from hydroxy aminoindan and phenethylamine as potential treatment for Alzheimer's disease. J Med Chem. 2002 Nov 21;45(24):5260-79.

Hanger DP, Gibb GM, de Silva R, Boutajangout A, Brion JP, Revesz T, Lees AJ, Anderton BH. The complex relationship between soluble and insoluble tau in tauopathies revealed by efficient dephosphorylation and specific antibodies. FEBS Lett. 2002 Nov 20;531(3):538-42.

Hasegawa K, Ono K, Yamada M, Naiki H. Kinetic modeling and determination of reaction constants of Alzheimer's beta-amyloid fibril extension and dissociation using surface plasmon resonance. Biochemistry. 2002 Nov 19;41(46):13489-98.

Goux WJ. The conformations of filamentous and soluble tau associated with Alzheimer paired helical filaments. Biochemistry. 2002 Nov 19;41(46):13798-806.

Cottingham MG, Hollinshead MS, Vaux DJ. Amyloid fibril formation by a synthetic peptide from a region of human acetylcholinesterase that is homologous to the Alzheimer's amyloid-beta peptide. Biochemistry. 2002 Nov 19;41(46):13539-47.

Gottlieb S. Long term HRT may protect women from Alzheimer's disease. BMJ. 2002 Nov 16;325(7373):1130A.

Dodart JC, Bales KR, Johnstone EM, Little SP, Paul SM. Apolipoprotein E alters the processing of the beta-amyloid precursor protein in APP(V717F) transgenic mice. Brain Res. 2002 Nov 15;955(1-2):191-9.

Kalaria R. Similarities between Alzheimer's disease and vascular dementia. J Neurol Sci. 2002 Nov 15;203-204(C):29-34.

Bowler JV. The concept of vascular cognitive impairment. J Neurol Sci. 2002 Nov 15;203-204(C):11-5.

Salloway S, Gur T, Berzin T, Zipser B, Correia S, Hovanesian V, Fallon J, Kuo-Leblanc V, Glass D, Hulette C, Rosenberg C, Vitek M, Stopa E. Effect of APOE genotype on microvascular basement membrane in Alzheimer's disease. J Neurol Sci. 2002 Nov 15;203-204:183-7.

Frölich L, Klinger T, Berger FM. Treatment with donepezil in Alzheimer patients with and without cerebrovascular disease. J Neurol Sci. 2002 Nov 15;203-204(C):137-9.

Erkinjuntti T. Treatment options. The latest evidence with galantamine (Reminyl(R)). J Neurol Sci. 2002 Nov 15;203-204(C):125-30.

Gerlai R, Fitch T, Bales KR, Gitter BD. Behavioral impairment of APP(V717F) mice in fear conditioning: is it only cognition? Behav Brain Res. 2002 Nov 15;136(2):503-9.

Lojkowska W, Ryglewicz D, Jedrzejczak T, Sienkiewicz-Jarosz H, Minc S, Jakubowska T, Kozlowicz-Gudzinska I. SPECT as a diagnostic test in the investigation of dementia. J Neurol Sci. 2002 Nov 15;203-204(C):215-9.

Sheng JG, Price DL, Koliatsos VE. Disruption of corticocortical connections ameliorates amyloid burden in terminal fields in a transgenic model of Abeta amyloidosis. J Neurosci. 2002 Nov 15;22(22):9794-9. ,
    


Lazarov O, Lee M, Peterson DA, Sisodia SS. Evidence that synaptically released beta-amyloid accumulates as extracellular deposits in the hippocampus of transgenic mice. J Neurosci. 2002 Nov 15;22(22):9785-93.
    

Tuszynski MH, U HS, Alksne J, Bakay RA, Pay MM, Merrill D, Thal LJ. Growth factor gene therapy for Alzheimer disease. Neurosurg Focus. 2002 Nov 15;13(5):e5.

Hashiguchi M, Saito T, Hisanaga S, Hashiguchi T. Truncation of CDK5 activator p35 induces intensive phosphorylation of Ser202/Thr205 of human tau. J Biol Chem. 2002 Nov 15;277(46):44525-30.

Ishii K, Klunk WE, Arawaka S, Debnath ML, Furiya Y, Sahara N, Shoji S, Tamaoka A, Pettegrew JW, Mori H. Chrysamine G and its derivative reduce amyloid beta-induced neurotoxicity in mice. Neurosci Lett. 2002 Nov 15;333(1):5-8.

Santucci AC, Perez S. Multiple injections of thyrotropin releasing hormone fail to reverse learning and memory deficits in rats with lesions of the nucleus basalis of meynert. Behav Brain Res. 2002 Nov 15;136(2):433-8.

Nunomura A, Chiba S, Kosaka K, Takeda A, Castellani RJ, Smith MA, Perry G. Neuronal RNA oxidation is a prominent feature of dementia with Lewy bodies. Neuroreport. 2002 Nov 15;13(16):2035-9.

Gatta LB, Albertini A, Ravid R, Finazzi D. Levels of beta-secretase BACE and alpha-secretase ADAM10 mRNAs in Alzheimer hippocampus. Neuroreport. 2002 Nov 15;13(16):2031-3.

Yin KJ, Lee JM, Chen SD, Xu J, Hsu CY. Amyloid-beta induces Smac release via AP-1/Bim activation in cerebral endothelial cells. J Neurosci. 2002 Nov 15;22(22):9764-70.

Fath T, Eidenmüller J, Brandt R. Tau-mediated cytotoxicity in a pseudohyperphosphorylation model of Alzheimer's disease. J Neurosci. 2002 Nov 15;22(22):9733-41.

Kuwako K, Nishimura I, Uetsuki T, Saido TC, Yoshikawa K. Activation of calpain in cultured neurons overexpressing Alzheimer amyloid precursor protein. Brain Res Mol Brain Res. 2002 Nov 15;107(2):166-75.

Demetriades AK. Functional neuroimaging in Alzheimer's type dementia. J Neurol Sci. 2002 Nov 15;203-204(C):247-51.

Bonelli RM, Aschoff A, Jirikowski G. Cerebrospinal fluid tissue transglutaminase in vascular dementia. J Neurol Sci. 2002 Nov 15;203-204(C):207-9.

Scheinfeld MH, Ghersi E, Laky K, Fowlkes BJ, D'Adamio L. Processing of beta-amyloid precursor-like protein-1 and -2 by gamma-secretase regulates transcription. J Biol Chem. 2002 Nov 15;277(46):44195-201.

Lue LF, Walker DG. Modeling Alzheimer's disease immune therapy mechanisms: interactions of human postmortem microglia with antibody-opsonized amyloid beta peptide. J Neurosci Res. 2002 Nov 15;70(4):599-610.

Maeck L, Meller J, Otto M, Stiens G, Wiltfang J, Stoppe G. Abeta peptide(1-42), Tau protein and S-100B protein level in cerebrospinal fluid of three patients with primary progressive aphasia. Neurosci Lett. 2002 Nov 15;333(1):33-6.

Mubumbila V, Sutter A, Ptok U, Heun R, Quirin-Stricker C. Identification of a single nucleotide polymorphism in the choline acetyltransferase gene associated with Alzheimer's disease. Neurosci Lett. 2002 Nov 15;333(1):9-12. ,

Pratt RD. Patient populations in clinical trials of the efficacy and tolerability of donepezil in patients with vascular dementia. J Neurol Sci. 2002 Nov 15;203-204:57-65.

O'Brien J, Lilienfeld S. Relevant clinical outcomes in probable vascular dementia and Alzheimer's disease with cerebrovascular disease. J Neurol Sci. 2002 Nov 15;203-204(C):41-8.

Schmidtke K, Hüll M. Neuropsychological differentiation of small vessel disease, Alzheimer's disease and mixed dementia. J Neurol Sci. 2002 Nov 15;203-204(C):17-22.

Borroni B, Akkawi N, Martini G, Colciaghi F, Prometti P, Rozzini L, Di Luca M, Lenzi GL, Romanelli G, Caimi L, Padovani A. Microvascular damage and platelet abnormalities in early Alzheimer's disease. J Neurol Sci. 2002 Nov 15;203-204(C):189-93.

Traykov L, Rigaud AS, Baudic S, Smagghe A, Boller F, Forette F. Apolipoprotein E varepsilon 4 allele frequency in demented and cognitively impaired patients with and without cerebrovascular disease. J Neurol Sci. 2002 Nov 15;203-204(C):177-81. ,

Jellinger KA. The pathology of ischemic-vascular dementia. An update. J Neurol Sci. 2002 Nov 15;203-204(C):153-7.

Grantham C, Geerts H. The rationale behind cholinergic drug treatment for dementia related to cerebrovascular disease. J Neurol Sci. 2002 Nov 15;203-204(C):131-6.

Bowirrat A, Friedland RP, Korczyn AD. Vascular dementia among elderly Arabs in Wadi Ara. J Neurol Sci. 2002 Nov 15;203-204(C):73-6.

Cecchi C, Fiorillo C, Sorbi S, Latorraca S, Nacmias B, Bagnoli S, Nassi P, Liguri G. Oxidative stress and reduced antioxidant defenses in peripheral cells from familial Alzheimer's patients. Free Radic Biol Med. 2002 Nov 15;33(10):1372-9.

Curtain CC, Ali FE, Smith DG, Bush AI, Masters CL, Barnham KJ. Metal ions, pH and cholesterol regulate the interactions of Alzheimer's disease amyloid-b peptide with membrane lipid. J Biol Chem. 2002 Nov 14;

Varner AE. Antioxidants and risk of Alzheimer disease. JAMA. 2002 Nov 13;288(18):2265; 

Stephenson J. The world in medicine: Alzheimer disease vaccine. JAMA. 2002 Nov 13;288(18):2257.

Brenner S. Antioxidants and risk of Alzheimer disease. JAMA. 2002 Nov 13;288(18):2265; 

Morris MC, Evans DA, Bienias JL, Tangney CC, Bennett DA, Aggarwal N, Wilson RS, Scherr PA. Antioxidants and risk of Alzheimer disease. JAMA. 2002 Nov 13;288(18):2265-6.

Engelhart MJ, Breteler MM. Antioxidants and risk of Alzheimer disease. JAMA. 2002 Nov 13;288(18):2265-6.

Gao L, Gabriel C, Lavoie T, Ye S. An Improved RSP Method to Detect HpaI Polymorphism in the Apolipoprotein C-1 Gene Promoter. BMC Med Genet. 2002 Nov 12;3(1):13.

Atamna H, Killilea DW, Killilea AN, Ames BN. Heme deficiency may be a factor in the mitochondrial and neuronal decay of aging. Proc Natl Acad Sci U S A. 2002 Nov 12;99(23):14807-12.

Dubois B, Touchon J, Portet F, Ousset PJ, Vellas B, Michel B. ["The 5 words": a simple and sensitive test for the diagnosis of Alzheimer's disease] Presse Med. 2002 Nov 9;31(36):1696-9.

Ma SL, Ng HK, Baum L, Pang JC, Chiu HF, Woo J, Tang NL, Lam LC. Low-density lipoprotein receptor-related protein 8 (apolipoprotein E receptor 2) gene polymorphisms in Alzheimer's disease. Neurosci Lett. 2002 Nov 8;332(3):216-8. ,

Infante J, Llorca J, Rodero L, Palacio E, Berciano J, Combarros O. Polymorphism at codon 174 of the prion-like protein gene is not associated with sporadic Alzheimer's disease. Neurosci Lett. 2002 Nov 8;332(3):213-5. ,


Zhu X, Yu QS, Cutler RG, Culmsee CW, Holloway HW, Lahiri DK, Mattson MP, Greig NH. Novel p53 inactivators with neuroprotective action: syntheses and pharmacological evaluation of 2-imino-2,3,4,5,6,7-hexahydrobenzothiazole and 2-imino-2,3,4,5,6,7-hexahydrobenzoxazole derivatives. J Med Chem. 2002 Nov 7;45(23):5090-7.
 

Kairane C, Roots K, Uusma T, Bogdanovic N, Karelson E, Kõks S, Zilmer M. Regulation of the frontocortical sodium pump by Na+ in Alzheimer's disease: difference from the age-matched control but similarity to the rat model. FEBS Lett. 2002 Nov 6;531(2):241-4.

Resnick SM, Henderson VW. Hormone therapy and risk of Alzheimer disease: a critical time. JAMA. 2002 Nov 6;288(17):2170-2.
 


Zandi PP, Carlson MC, Plassman BL, Welsh-Bohmer KA, Mayer LS, Steffens DC, Breitner JC, Cache County Memory Study Investigators. Hormone replacement therapy and incidence of Alzheimer disease in older women: the Cache County Study. JAMA. 2002 Nov 6;288(17):2123-9.

de Jong D, Jansen RW, Verbeek MM, Kremer HP. [In Process Citation] Ned Tijdschr Geneeskd. 2002 Nov 2;146(44):2074-8.

Huang HM, Kuo YM, Ou HC, Lin CC, Chuo LJ. Apolipoprotein E polymorphism in various dementias in Taiwan Chinese population. J Neural Transm. 2002 Nov;109(11):1415-21.

Neugroschl J, Davis KL. Biological markers in Alzheimer disease. Am J Geriatr Psychiatry. 2002 Nov-Dec;10(6):660-77.

Selkoe DJ. Deciphering the genesis and fate of amyloid beta-protein yields novel therapies for Alzheimer disease. J Clin Invest. 2002 Nov 1;110(10):1375-81.
 

Honda N, Machida K, Hosono M, Matsumoto T, Matsuda H, Oshima M, Koizumi K, Kosuda S, Momose T, Mori Y, Hashimoto J, Shimizu Y. Interobserver variation in diagnosis of dementia by brain perfusion SPECT. Radiat Med. 2002 Nov-Dec;20(6):281-9.

Spiegel R. [Rivastigmine: a review of its clinical effectiveness] Rev Neurol. 2002 Nov 1;35(9):859-69.

Kaufer D. [Treatment of neuropsychiatric symptoms in Alzheimer s disease] Rev Neurol. 2002 Nov 1;35(9):846-50.

Smith-Gamble V, Baiyewu O, Perkins AJ, Gureje O, Hall KS, Ogunniyi A, Hui SL, Hendrie HC. Informant reports of changes in personality predict dementia in a population-based study of elderly african americans and yoruba. Am J Geriatr Psychiatry. 2002 Nov-Dec;10(6):724-32.

Ahmed S, Mozley PD, Potter WZ. Biomarkers in psychotropic drug development. Am J Geriatr Psychiatry. 2002 Nov-Dec;10(6):678-86.

Town T, Vendrame M, Patel A, Poetter D, Delledonne A, Mori T, Smeed R, Crawford F, Klein T, Tan J, Mullan M. Reduced Th1 and enhanced Th2 immunity after immunization with Alzheimer's beta-amyloid(1-42). J Neuroimmunol. 2002 Nov 1;132(1-2):49-59.

Granholm AC, Ford KA, Hyde LA, Bimonte HA, Hunter CL, Nelson M, Albeck D, Sanders LA, Mufson EJ, Crnic LS. Estrogen restores cognition and cholinergic phenotype in an animal model of Down syndrome. Physiol Behav. 2002 Nov;77(2-3):371-85.

Larson E. Galantamine improved cognition and global functioning in vascular dementia or Alzheimer disease with cerebrovascular disease. ACP J Club. 2002 Nov-Dec;137(3):102.


None None. Hormone replacement therapy and incidence of Alzheimer disease in older women: the cache county study. JAMA 2002 Nov 6;288(17):2123-9. 2002 Nov;288(17):2123-9. Abstract
 

Kovács GG, Trabattoni G, Hainfellner JA, Ironside JW, Knight RS, Budka H. Mutations of the prion protein gene phenotypic spectrum. J Neurol. 2002 Nov;249(11):1567-82.

Dickson DW, Bergeron C, Chin SS, Duyckaerts C, Horoupian D, Ikeda K, Jellinger K, Lantos PL, Lippa CF, Mirra SS, Tabaton M, Vonsattel JP, Wakabayashi K, Litvan I, Office of Rare Diseases of the National Institutes of Health. Office of Rare Diseases neuropathologic criteria for corticobasal degeneration. J Neuropathol Exp Neurol. 2002 Nov;61(11):935-46.
 

Biernat J, Wu YZ, Timm T, Zheng-Fischhöfer Q, Mandelkow E, Meijer L, Mandelkow EM. Protein Kinase MARK/PAR-1 Is Required for Neurite Outgrowth and Establishment of Neuronal Polarity. Mol Biol Cell. 2002 Nov;13(11):4013-28.

Lange KL, Bondi MW, Salmon DP, Galasko D, Delis DC, Thomas RG, Thal LJ. Decline in verbal memory during preclinical Alzheimer's disease: examination of the effect of APOE genotype. J Int Neuropsychol Soc. 2002 Nov;8(7):943-55. ,

Kantarci K, Smith GE, Ivnik RJ, Petersen RC, Boeve BF, Knopman DS, Tangalos EG, Jack CR. 1H magnetic resonance spectroscopy, cognitive function, and apolipoprotein E genotype in normal aging, mild cognitive impairment and Alzheimer's disease. J Int Neuropsychol Soc. 2002 Nov;8(7):934-42.

Cook L, Brayne CE, Easton D, Evans JG, Xuereb J, Cairns NJ, Rubinsztein DC. No evidence for an association between Saitohin Q7R polymorphism and Alzheimer's disease. Ann Neurol. 2002 Nov;52(5):690-1. ,
 

Hur K, Kim JI, Choi SI, Choi EK, Carp RI, Kim YS. The pathogenic mechanisms of prion diseases. Mech Ageing Dev. 2002 Nov;123(12):1637-47.
 

Bishop GM, Robinson SR. The amyloid hypothesis: let sleeping dogmas lie? Neurobiol Aging. 2002 Nov-Dec;23(6):1101-5.
 

Holtzman DM. Abeta conformational change is central to Alzheimer's disease. Neurobiol Aging. 2002 Nov-Dec;23(6):1085-8.

Robinson SR, Bishop GM. Abeta as a bioflocculant: implications for the amyloid hypothesis of Alzheimer's disease. Neurobiol Aging. 2002 Nov-Dec;23(6):1051-72.

Karlawish JH, Clark CM. Addressing the challenges of transforming laboratory advances into Alzheimer's Disease treatments. Neurobiol Aging. 2002 Nov-Dec;23(6):1043-9.

Lee VM. Amyloid binding ligands as Alzheimer's disease therapies. Neurobiol Aging. 2002 Nov-Dec;23(6):1039-42.

Bush AI. Metal complexing agents as therapies for Alzheimer's disease. Neurobiol Aging. 2002 Nov-Dec;23(6):1031-8.

Williams JH, Pereira EA, Budge MM, Bradley KM. Minimal hippocampal width relates to plasma homocysteine in community-dwelling older people. Age Ageing. 2002 Nov;31(6):440-4.

Pratt RD, Perdomo CA, Surick IW, Ieni JR. Donepezil: tolerability and safety in Alzheimer's disease. Int J Clin Pract. 2002 Nov;56(9):710-7.

Beach TG. Muscarinic agonists as preventative therapy for Alzheimer's disease. Curr Opin Investig Drugs. 2002 Nov 1;3(11):1633-6.

Lilienfeld S, Kurz A. Broad therapeutic benefits in patients with probable vascular dementia or Alzheimer's disease with cerebrovascular disease treated with galantamine. Ann N Y Acad Sci. 2002 Nov;977:487-92.

Kurz A. A novel treatment for patients with Alzheimer's disease and with vascular dementia. Ann N Y Acad Sci. 2002 Nov;977:476-81.

Kondo M, Imahori Y, Mori S, Nakajima K. Inositol phospholipid metabolism in Alzheimer's disease: a positron emission tomographic study. Ann N Y Acad Sci. 2002 Nov;977:416-22.

Yanagisawa K, Matsuzaki K. Cholesterol-dependent aggregation of amyloid beta-protein. Ann N Y Acad Sci. 2002 Nov;977:384-6.

Kudo T, Katayama T, Imaizumi K, Yasuda Y, Yatera M, Okochi M, Tohyama M, Takeda M. The unfolded protein response is involved in the pathology of Alzheimer's disease. Ann N Y Acad Sci. 2002 Nov 1;977:349-55.

Casoli T, Di Stefano G, Delfino A, Solazzi M, Fattoretti P, Bertoni-Freddari C, Guidi M, Scarpino O, Giunta S, Galeazzi L. Beta-amyloid fragment 25-35 selectively damages platelets from patients with Alzheimer's disease. Ann N Y Acad Sci. 2002 Nov;977:296-302.

Van Nostrand WE, Melchor JP, Romanov G, Zeigler K, Davis J. Pathogenic effects of cerebral amyloid angiopathy mutations in the amyloid beta-protein precursor. Ann N Y Acad Sci. 2002 Nov;977:258-65.

Kenny RA, Kalaria R, Ballard C. Neurocardiovascular instability in cognitive impairment and dementia. Ann N Y Acad Sci. 2002 Nov;977:183-95.

Otsuka M, Yamaguchi K, Ueki A. Similarities and differences between Alzheimer's disease and vascular dementia from the viewpoint of nutrition. Ann N Y Acad Sci. 2002 Nov;977:155-61.

Dantoine TF, Debord J, Merle L, Lacroix-Ramiandrisoa H, Bourzeix L, Charmes JP. Paraoxonase 1 activity: a new vascular marker of dementia? Ann N Y Acad Sci. 2002 Nov;977:96-101.

Skoog I, Gustafson D. Hypertension and related factors in the etiology of Alzheimer's disease. Ann N Y Acad Sci. 2002 Nov 1;977:29-36.

Karelson E, Mahlapuu R, Zilmer M, Soomets U, Bogdanovic N, Langel U. Possible signaling by glutathione and its novel analogue through potent stimulation of fontocortical G proteins in normal aging and in Alzheimer's disease. Ann N Y Acad Sci. 2002 Nov;973:537-40.

Lahiri DK, Alley GM, Ge YW, Du Y. Functional characterization of the 5'-regulatory region of the murine apolipoprotein gene. Ann N Y Acad Sci. 2002 Nov;973:340-4.

Jang JH, Surh YJ. beta-Amyloid induces oxidative DNA damage and cell death through activation of c-Jun N terminal kinase. Ann N Y Acad Sci. 2002 Nov;973:228-36.

Vamvakidès A. [Mechanism of action of tetrahydro-N, N-dimethyl-5, 5-diphenyl-3-furanemethanamine, a putative nootropic, anti-epileptic and antidepressant compound] Ann Pharm Fr. 2002 Nov;60(6):415-22.

Kölsch H, Rao ML. Neuroprotective effects of estradiol-17beta: implications for psychiatric disorders. Arch Women Ment Health. 2002 Nov;5(3):105-10.

Rohn TT, Rissman RA, Davis MC, Kim YE, Cotman CW, Head E. Caspase-9 activation and caspase cleavage of tau in the Alzheimer's disease brain. Neurobiol Dis. 2002 Nov 1;11(2):341-54.

Kumar-Singh S, Julliams A, Nuydens R, Ceuterick C, Labeur C, Serneels S, Vennekens K, Van Osta P, Geerts H, De Strooper B, van Broeckhoven C. In vitro studies of Flemish, Dutch, and wild-type beta-amyloid provide evidence for two-staged neurotoxicity. Neurobiol Dis. 2002 Nov;11(2):330-40.

Poduslo JF, Wengenack TM, Curran GL, Wisniewski T, Sigurdsson EM, Macura SI, Borowski BJ, Jack CR. Molecular targeting of Alzheimer's amyloid plaques for contrast-enhanced magnetic resonance imaging. Neurobiol Dis. 2002 Nov;11(2):315-29.

Picklo MJ, Montine TJ, Amarnath V, Neely MD. Carbonyl toxicology and Alzheimer's disease. Toxicol Appl Pharmacol. 2002 Nov 1;184(3):187-97.

Gray-Vickrey P. Advances in Alzheimer's disease. Nursing. 2002 Nov;32(11 Pt 1):64.

Zekry D, Duyckaerts C, Belmin J, Geoffre C, Moulias R, Hauw JJ. Alzheimer's disease and brain infarcts in the elderly Agreement with neuropathology. J Neurol. 2002 Nov;249(11):1529-34.

Bigler ED, Tate DF, Miller MJ, Rice SA, Hessel CD, Earl HD, Tschanz JT, Plassman B, Welsh-Bohmer KA. Dementia, asymmetry of temporal lobe structures, and apolipoprotein E genotype: relationships to cerebral atrophy and neuropsychological impairment. J Int Neuropsychol Soc. 2002 Nov;8(7):925-33.

Xu G, Meyer JS, Thornby J, Chowdhury M, Quach M. Screening for mild cognitive impairment (MCI) utilizing combined mini-mental-cognitive capacity examinations for identifying dementia prodromes. Int J Geriatr Psychiatry. 2002 Nov;17(11):1027-33.

Le Y, Murphy PM, Wang JM. Formyl-peptide receptors revisited. Trends Immunol. 2002 Nov;23(11):541-8.

Micchelli CA, Esler WP, Kimberly WT, Jack C, Berezovska O, Kornilova A, Hyman BT, Perrimon N, Wolfe MS. g-Secretase/presenilin inhibitors for Alzheimer's disease phenocopy Notch mutations in Drosophila. FASEB J. 2002 Nov 1;

Crescenzi O, Tomaselli S, Guerrini R, Salvadori S, D'Ursi AM, Temussi PA, Picone D. Solution structure of the Alzheimer amyloid beta-peptide (1-42) in an apolar microenvironment. Similarity with a virus fusion domain. Eur J Biochem. 2002 Nov 1;269(22):5642-8.

McGeer PL, McGeer EG. The possible role of complement activation in Alzheimer disease. Trends Mol Med. 2002 Nov;8(11):519-23.

Morihara T, Chu T, Ubeda O, Beech W, Cole GM. Selective inhibition of Abeta42 production by NSAID R-enantiomers. J Neurochem. 2002 Nov;83(4):1009-12.
 

Allen B, Ingram E, Takao M, Smith MJ, Jakes R, Virdee K, Yoshida H, Holzer M, Craxton M, Emson PC, Atzori C, Migheli A, Crowther RA, Ghetti B, Spillantini MG, Goedert M. Abundant tau filaments and nonapoptotic neurodegeneration in transgenic mice expressing human P301S tau protein. J Neurosci. 2002 Nov 1;22(21):9340-51.

Dechant G, Barde YA. The neurotrophin receptor p75(NTR): novel functions and implications for diseases of the nervous system. Nat Neurosci. 2002 Nov;5(11):1131-6.

Citron M. Alzheimer's disease: treatments in discovery and development. Nat Neurosci. 2002 Nov;5 Suppl:1055-7.

Kemp JA, McKernan RM. NMDA receptor pathways as drug targets. Nat Neurosci. 2002 Nov;5 Suppl:1039-42.

Adunsky A, Chesnin V, Davidson M, Gerber Y, Alexander K, Haratz D. A cross-sectional study of lipids and ApoC levels in Alzheimer's patients with and without cardiovascular disease. J Gerontol A Biol Sci Med Sci. 2002 Nov;57(11):M757-61.

Schulz S, Schagdarsurengin U, Greiser P, Birkenmeier G, Müller-Werdan U, Hagemann M, Riemann D, Werdan K, Gläser C. The LDL receptor-related protein (LRP1/A2MR) and coronary atherosclerosis--novel genomic variants and functional consequences. Hum Mutat. 2002 Nov;20(5):404.

Tanahashi H, Asada T, Tabira T. c954C-->T polymorphism in the Fe65L2 gene is associated with early-onset Alzheimer's disease. Ann Neurol. 2002 Nov;52(5):691-3.
 

Feinstein D, Heneka M, Gavrilyuk V, Russo C, Weinberg G, Galea E. Noradrenergic regulation of inflammatory gene expression in brain. Neurochem Int. 2002 Nov;41(5):357.
 

Seo JH, Rah JC, Choi SH, Shin JK, Min K, Kim HS, Park CH, Kim S, Kim EM, Lee SH, Lee S, Suh SW, Suh YH. Alpha-synuclein regulates neuronal survival via Bcl-2 family expression and PI3/Akt kinase pathway. FASEB J. 2002 Nov;16(13):1826-8.

  
Hock C, Konietzko U, Papassotiropoulos A, Wollmer A, Streffer J, Von Rotz RC, Davey G, Moritz E, Nitsch RM. Generation of antibodies specific for beta-amyloid by vaccination of patients with Alzheimer disease. Nat Med. 2002 Nov;8(11):1270-5.
    

Bowen RL, Smith MA, Harris PL, Kubat Z, Martins RN, Castellani RJ, Perry G, Atwood CS. Elevated luteinizing hormone expression colocalizes with neurons vulnerable to Alzheimer's disease pathology. J Neurosci Res. 2002 Nov 1;70(3):514-8.

Kubo T, Nishimura S, Kumagae Y, Kaneko I. In vivo conversion of racemized beta-amyloid ([D-Ser 26]A beta 1-40) to truncated and toxic fragments ([D-Ser 26]A beta 25-35/40) and fragment presence in the brains of Alzheimer's patients. J Neurosci Res. 2002 Nov 1;70(3):474-83.
 

Colangelo V, Schurr J, Ball MJ, Pelaez RP, Bazan NG, Lukiw WJ. Gene expression profiling of 12633 genes in Alzheimer hippocampal CA1: transcription and neurotrophic factor down-regulation and up-regulation of apoptotic and pro-inflammatory signaling. J Neurosci Res. 2002 Nov 1;70(3):462-73.
 

Teter B, Ashford JW. Neuroplasticity in Alzheimer's disease. J Neurosci Res. 2002 Nov 1;70(3):402-37.

Morishima-Kawashima M, Ihara Y. Alzheimer's disease: beta-Amyloid protein and tau. J Neurosci Res. 2002 Nov 1;70(3):392-401.
 

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Richardson RL, Kim EM, Shephard RA, Gardiner T, Cleary J, O'Hare E. Behavioural and histopathological analyses of ibuprofen treatment on the effect of aggregated Abeta(1-42) injections in the rat. Brain Res. 2002 Nov 1;954(1):1-10.

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Dewachter I, Van Leuven F. Secretases as targets for the treatment of Alzheimer's disease: the prospects Lancet Neurology. 2002 Nov 1;1(7):409-416. Full Text for Subscribers

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