Alzheimer’s Research Papers ~ July 2002 ~ Beta Amyloid Blog

2002: July: Alzheimer’s Research Papers    

           

Hardy J, Selkoe DJ. The amyloid hypothesis of Alzheimer's disease: progress and problems on the road to therapeutics. Science. 2002 Jul 19;297(5580):353-6.

 

Papassotiropoulos A, Lewis HD, Bagli M, Jessen F, Ptok U, Schulte A, Shearman MS, Heun R. Cerebrospinal fluid levels of beta-amyloid(42) in patients with Alzheimer's disease are related to the exon 2 polymorphism of the cathepsin D gene. Neuroreport. 2002 Jul 19;13(10):1291-1294. ,

Jain NK, Patil CS, Kulkarni SK, Singh A. Modulatory role of cyclooxygenase inhibitors in aging- and scopolamine or lipopolysaccharide-induced cognitive dysfunction in mice. Behav Brain Res. 2002 Jul 18;133(2):369-76.

Lashuel HA, Hartley D, Petre BM, Walz T, Lansbury PT. Neurodegenerative disease: amyloid pores from pathogenic mutations. Nature. 2002 Jul 18;418(6895):291.

Romero-Isart N, Jensen LT, Zerbe O, Winge DR, Vasak M. Engineering of metallothionein-3 neuroinhibitory activity into the inactive isoform metallothionein-1. J Biol Chem. 2002 Jul 18;

Devred F, Douillard S, Briand C, Peyrot V. First tau repeat domain binding to growing and taxol-stabilized microtubules, and serine 262 residue phosphorylation. FEBS Lett. 2002 Jul 17;523(1-3):247-51.

Tseng HC, Zhou Y, Shen Y, Tsai LH. A survey of Cdk5 activator p35 and p25 levels in Alzheimer's disease brains. FEBS Lett. 2002 Jul 17;523(1-3):58-62.

Basu A, Krady JK, O'Malley M, Styren SD, DeKosky ST, Levison SW. The type 1 interleukin-1 receptor is essential for the efficient activation of microglia and the induction of multiple proinflammatory mediators in response to brain injury. J Neurosci. 2002 Jul 15;22(14):6071-82.

Palu E, Liesi P. Differential distribution of laminins in Alzheimer disease and normal human brain tissue. J Neurosci Res. 2002 Jul 15;69(2):243-56.

Pappolla MA, Smith MA, Bryant-Thomas T, Bazan N, Petanceska S, Perry G, Thal LJ, Sano M, Refolo LM. Cholesterol, oxidative stress, and Alzheimer's disease: expanding the horizons of pathogenesis(1). Free Radic Biol Med. 2002 Jul 15;33(2):173-81.

 

Peng QL, Buz'Zard AR, Lau BH. Pycnogenol((R)) protects neurons from amyloid-beta peptide-induced apoptosis. Brain Res Mol Brain Res. 2002 Jul 15;104(1):55-65.

Arélin K, Kinoshita A, Whelan CM, Irizarry MC, Rebeck GW, Strickland DK, Hyman BT. LRP and senile plaques in Alzheimer's disease: colocalization with apolipoprotein E and with activated astrocytes. Brain Res Mol Brain Res. 2002 Jul 15;104(1):38-46.

Guo JT, Yu J, Grass D, de Beer FC, Kindy MS. Inflammation-dependent cerebral deposition of serum amyloid a protein in a mouse model of amyloidosis. J Neurosci. 2002 Jul 15;22(14):5900-9.

Behl C, Moosmann B. Antioxidant neuroprotection in Alzheimer's disease as preventive and therapeutic approach(2). Free Radic Biol Med. 2002 Jul 15;33(2):182-91.

 

Wojtowicz WM, Farzan M, Joyal JL, Carter K, Babcock GJ, Israel DI, Sodroski J, Mirzabekov T. Stimulation of enveloped virus infection by beta-amyloid fibrils. J Biol Chem. 2002 Jul 15;

Bodor N, Buchwald P. Barriers to remember: brain-targeting chemical delivery systems and Alzheimer's disease. Drug Discov Today. 2002 Jul 15;7(14):766-74.

 

Burns A, Byrne EJ, Maurer K. Alzheimer's disease. Lancet. 2002 Jul 13;360(9327):163-5.

Morimoto A, Irie K, Murakami K, Ohigashi H, Shindo M, Nagao M, Shimizu T, Shirasawa T. Aggregation and neurotoxicity of mutant amyloid beta (Abeta) peptides with proline replacement: importance of turn formation at positions 22 and 23. Biochem Biophys Res Commun. 2002 Jul 12;295(2):306-11.

Shirotani K, Tsubuki S, Lee HJ, Maruyama K, Saido TC. Generation of amyloid beta peptide with pyroglutamate at position 3 in primary cortical neurons. Neurosci Lett. 2002 Jul 12;327(1):25-8.

 

Wang J, Ikonen S, Gurevicius K, van Groen T, Tanila H. Alteration of cortical EEG in mice carrying mutated human APP transgene. Brain Res. 2002 Jul 12;943(2):181-90.

Simmonds A. The emerging neurobiology of cholesterol Neurobiology of Lipids. 2002 July 10;1(1):1-4. Full Text

Turner RT, Loy JA, Nguyen C, Devasamudram T, Ghosh AK, Koelsch G, Tang J. Specificity of Memapsin 1 and Its Implications on the Design of Memapsin 2 (beta-Secretase) Inhibitor Selectivity. Biochemistry. 2002 Jul 9;41(27):8742-8746.

Hoyer S. Cholesterol and Alzheimer's disease. Neurology. 2002 Jul 9;59(1):150-1.

 

Itzhaki RF, Dobson CB. Alzheimer's disease and herpes. CMAJ. 2002 Jul 9;167(1):13.

 

Taylor GS, Vipond IB, Paul ID, Matthews S, Wilcock GK, Caul EO. Failure to correlate C. pneumoniae with late onset Alzheimer's disease. Neurology. 2002 Jul 9;59(1):142-3.

Bacanu SA, Devlin B, Chowdari KV, DeKosky ST, Nimgaonkar VL, Sweet RA. Linkage analysis of Alzheimer disease with psychosis. Neurology. 2002 Jul 9;59(1):118-20.

Lambert JC, Araria-Goumidi L, Myllykangas L, Ellis C, Wang JC, Bullido MJ, Harris JM, Artiga MJ, Hernandez D, Kwon JM, Frigard B, Petersen RC, Cumming AM, Pasquier F, Sastre I, Tienari PJ, Frank A, Sulkava R, Morris JC, St Clair D, Mann DM, Wavrant-DeVrièze F, Ezquerra-Trabalon M, Amouyel P, Hardy J, Haltia M, Valdivieso F, Goate AM, Pérez-Tur J, Lendon CL, Chartier-Harlin MC. Contribution of APOE promoter polymorphisms to Alzheimer's disease risk. Neurology. 2002 Jul 9;59(1):59-66. , ,

Chen Q, Kimura H, Schubert D. A novel mechanism for the regulation of amyloid precursor protein metabolism. J Cell Biol. 2002 Jul 8;158(1):79-89.

 

Alvarez V, Mata IF, González P, Lahoz CH, Martínez C, Peña J, Guisasola LM, Coto E. Association between the TNFalpha-308 A/G polymorphism and the onset-age of Alzheimer disease. Am J Med Genet. 2002 Jul 8;114(5):574-7. ,

Roks G, Cruts M, Houwing-Duistermaat JJ, Dermaut B, Serneels S, Havekes LM, Hofman A, Breteler MM, van Broeckhoven C, van Duijn CM. Effect of the APOE-491A/T promoter polymorphism on apolipoprotein E levels and risk of Alzheimer disease: The Rotterdam Study. Am J Med Genet. 2002 Jul 8;114(5):570-3. ,

Josefson D. Foods rich in antioxidants may reduce risk of Alzheimer's disease. BMJ. 2002 Jul 6;325(7354):7.

Beyer K, Lao JI, Gómez M, Riutort N, Latorre P, Mate JL, Ariza A. The Th1/E47cs-G apolipoprotein E (APOE) promoter allele is a risk factor for Alzheimer disease of very later onset. Neurosci Lett. 2002 Jul 5;326(3):187-90. ,

 

Dessolin J, Schuler M, Quinart A, De Giorgi F, Ghosez L, Ichas F. Selective targeting of synthetic antioxidants to mitochondria: towards a mitochondrial medicine for neurodegenerative diseases? Eur J Pharmacol. 2002 Jul 5;447(2-3):155-61.

Uversky VN, Fink AL. Amino acid determinants of alpha-synuclein aggregation: putting together pieces of the puzzle. FEBS Lett. 2002 Jul 3;522(1-3):9-13.

Choi J, Conrad CC, Malakowsky CA, Talent JM, Yuan CS, Gracy RW. Flavones from Scutellaria baicalensis Georgi attenuate apoptosis and protein oxidation in neuronal cell lines. Biochim Biophys Acta. 2002 Jul 3;1571(3):201-210.

Muchowski PJ. Protein misfolding, amyloid formation, and neurodegeneration: a critical role for molecular chaperones? Neuron. 2002 Jul 3;35(1):9-12.

 

Hashimoto M, Sagara Y, Langford D, Everall IP, Mallory M, Everson A, Digicaylioglu M, Masliah E. Fibroblast growth factor 1 regulates signaling via the GSK3beta pathway: implications for neuroprotection. J Biol Chem. 2002 Jul 2;

Fisher KE, Fei Q, Laird ER, Stock JL, Allen MR, Sahagan BG, Strick CA. Engineering autoactivating forms of matrix metalloproteinase-9 and expression of the active enzyme in cultured cells and transgenic mouse brain. Biochemistry. 2002 Jul 2;41(26):8289-97.

Takahashi Y, Ueno A, Mihara H. Amyloid architecture: complementary assembly of heterogeneous combinations of three or four peptides into amyloid fibrils. Chembiochem. 2002 Jul 2;3(7):637-42.

Lai MK, Tsang SW, Francis PT, Keene J, Hope T, Esiri MM, Spence I, Chen CP. Postmortem serotoninergic correlates of cognitive decline in Alzheimer's disease. Neuroreport. 2002 Jul 2;13(9):1175-8.

Wilkinson DG, Passmore AP, Bullock R, Hopker SW, Smith R, Potocnik FC, Maud CM, Engelbrecht I, Hock C, Ieni JR, Bahra RS. A multinational, randomised, 12-week, comparative study of donepezil and rivastigmine in patients with mild to moderate Alzheimer's disease. Int J Clin Pract. 2002 Jul-Aug;56(6):441-6.

Graeber MB, Moran LB. Mechanisms of cell death in neurodegenerative diseases: fashion, fiction, and facts. Brain Pathol. 2002 Jul;12(3):385-90.

Chase GA, Geller G, Havstad SL, Holtzman NA, Spear Bassett S. Physicians' propensity to offer genetic testing for Alzheimer's disease: Results from a survey. Genet Med. 2002 Jul-Aug;4(4):297-303.

Namba H, Fukushi K, Nagatsuka S, Iyo M, Shinotoh H, Tanada S, Irie T. Positron emission tomography: quantitative measurement of brain acetylcholinesterase activity using radiolabeled substrates. Methods. 2002 Jul;27(3):242.

 

Peck JA, Stopa EG. Agrin and microvascular damage in Alzheimer's disease. Med Health R I. 2002 Jul;85(7):202-6.

Akintola-Ogunremi O, Whitney C, Mathur SC, Finch CN. Chronic lymphocytic leukemia presenting with symptomatic central nervous system involvement. Ann Hematol. 2002 Jul;81(7):402-4.

Ping SE, Greferath U, Barrett GL. Estrogen treatment suppresses forebrain p75 neurotrophin receptor expression in aged, noncycling female rats. J Neurosci Res. 2002 Jul 1;69(1):51-60.

Giacobini E, Spiegel R, Enz A, Veroff AE, Cutler NR. Inhibition of acetyl- and butyryl-cholinesterase in the cerebrospinal fluid of patients with Alzheimer's disease by rivastigmine: correlation with cognitive benefit. J Neural Transm. 2002 Jul;109(7-8):1053-65.

Felber SR. Magnetic resonance in the differential diagnosis of dementia. J Neural Transm. 2002 Jul;109(7-8):1045-51.

Newhouse P, Tatro A, Naylor M, Quealey K, Delgado P. Alzheimer disease, serotonin systems, and tryptophan depletion. Am J Geriatr Psychiatry. 2002 Jul-Aug;10(4):483-4.

Maia L, de Mendonça A. Does caffeine intake protect from Alzheimer's disease? Eur J Neurol. 2002 Jul;9(4):377-82.

Solá S, Diógenes MJ, Brites D, Rodrigues CM. [In Process Citation] Acta Med Port. 2002 Jul-Aug;15(4):269-75.

Zhang Z, Wang X, Chen Q, et Al . [Clinical efficacy and safety of huperzine Alpha in treatment of mild to moderate Alzheimer disease, a placebo-controlled, double-blind, randomized trial] Zhonghua Yi Xue Za Zhi. 2002 Jul;82(14):941-4.

 

Reisberg B, Franssen EH, Souren LE, Auer SR, Akram I, Kenowsky S. Evidence and mechanisms of retrogenesis in Alzheimer's and other dementias: management and treatment import. Am J Alzheimers Dis Other Demen. 2002 Jul-Aug;17(4):202-12.

 

Fukuyama H. [Neuroimaging--recent issues and future progresses] Nippon Ronen Igakkai Zasshi. 2002 Jul;39(4):364-70.

Suda N. [Vascular dementia with a suspicion of Alzheimer's disease in early stage] No To Shinkei. 2002 Jul;54(7):631-9.

Ermak G, Davies KJ. Gene expression in Alzheimer's disease. Drugs Today (Barc). 2002 Jul;38(7):509-16.

Davydova TV, Mikovskaya OI, Fomina VG, Voskresenskaya NI, Doronina OA. Induction of immune complexes and autoantibodies to serotonin and dopamine in patients with Alzheimer's disease. Bull Exp Biol Med. 2002 Jul;134(1):23-5.

Perkins D. Targeting apoptosis in neurological disease using the herpes simplex virus. J Cell Mol Med. 2002 Jul-Sep;6(3):341-56.

Hauw JJ, Zekry D, Seilhean D, Forette B, Gallinari C, Laurent M, Moulias R, Piette F, Sachet A, Duyckaerts C. [Neuropathology of the cerebral vessels of centenarians] J Mal Vasc. 2002 Jul;27 Spec No:S13-8.

Mahady GB. Ginkgo biloba for the prevention and treatment of cardiovascular disease: a review of the literature. J Cardiovasc Nurs. 2002 Jul;16(4):21-32.

Tréton J. [Fundamental aspects of extreme aging] J Mal Vasc. 2002 Jul;27 Spec No:S19-23.

Albensi BC. Biological Mechanisms, Cerebrovascular Alterations and Pharmacological Targets in the Pathology of Dementia. Drug News Perspect. 2002 Jul;15(6):333-337.

Silverman DH, Cummings JL, Small GW, Gambhir SS, Chen W, Czernin J, Phelps ME. Added clinical benefit of incorporating 2-deoxy-2-[18F]fluoro-D-glucose with positron emission tomography into the clinical evaluation of patients with cognitive impairment. Mol Imaging Biol. 2002 Jul 1;4(4):283-93.

Koistinaho M, Kettunen MI, Holtzman DM, Kauppinen RA, Higgins LS, Koistinaho J. Expression of human apolipoprotein e downregulates amyloid precursor protein-induced ischemic susceptibility. Stroke. 2002 Jul;33(7):1905-10.

Saling MM, Maccuspie-Moore CM, Anderson VA, Chiu E. "Clockness" in the detection of dementia: a semantic-conceptual effect. Brain Cogn. 2002 Jul;49(2):205-7.

Zakzanis KK, Leach L. Evidence for a shrinking span of personal and present existence in dementia of the Alzheimer's type. Brain Cogn. 2002 Jul;49(2):249-53.

Jonas S, Van Heertum R, Tikofsky R, Millman E, Singh D, Brust J, McCurtis H, Locko R. rCBF/SPECT in the evaluation of inner-city minority patients with a history of impaired memory: a pilot blind read pre- and poststudy. Brain Cogn. 2002 Jul;49(2):234-7.

Strang JM, Donnelly KZ, Grohman K, Kleiner J. Verbal learning and visuomotor attention in Alzheimer's disease and geriatric depression. Brain Cogn. 2002 Jul;49(2):216-20.

Jones S, Small BJ, Fratiglioni L, Backman L. Predictors of cognitive change from preclinical to clinical Alzheimer's disease. Brain Cogn. 2002 Jul;49(2):210-3.

Mandzia J, Black S, Grady C, McAndrews MP, Graham S. Encoding and retrieval in aging and memory loss, a fMRI study. Brain Cogn. 2002 Jul;49(2):225-8.

Purdy KS, McMullen PA, Freedman M. Changes to the object recognition system in patients with dementia of the Alzheimer's type. Brain Cogn. 2002 Jul;49(2):213-6.

Kixmiller JS. Evaluation of prospective memory training for individuals with mild Alzheimer's disease. Brain Cogn. 2002 Jul;49(2):237-41.

Engeland C, Mahoney C, Mohr E, Ilivitsky V, Knott V. Nicotine and sensory memory in Alzheimer's disease: an event-related potential study. Brain Cogn. 2002 Jul;49(2):232-4.

Poulin P, Zakzanis KK. In vivo neuroanatomy of Alzheimer's disease: evidence from structural and functional brain imaging. Brain Cogn. 2002 Jul;49(2):220-5.

Simard M, van Reekum R, Myran D, Panisset M, Cohen T, Freedman M, Black S, Suvajac B. Differential memory impairment in dementia with Lewy bodies and Alzheimer's disease. Brain Cogn. 2002 Jul;49(2):244-9.

Motonaga T, Asada T. [A 7-year follow-up study of cases with dementia to identify predictors of mortality] Nippon Koshu Eisei Zasshi. 2002 Jul;49(7):620-30.

Mador J, Clark M, Crotty M, Hecker J. Utility-weighted measures of quality of life in Alzheimer disease. Alzheimer Dis Assoc Disord. 2002 Jul-Sep;16(3):202.

Xu G, Gonzales V, Borchelt DR. Rapid detection of protein aggregates in the brains of Alzheimer patients and transgenic mouse models of amyloidosis. Alzheimer Dis Assoc Disord. 2002 Jul-Sep;16(3):191-5.

Arvanitakis Z, Lucas JA, Younkin LH, Younkin SG, Graff-Radford NR. Serum creatinine levels correlate with plasma amyloid Beta protein. Alzheimer Dis Assoc Disord. 2002 Jul-Sep;16(3):187-90.

Waters G, Caplan D. Working memory and online syntactic processing in Alzheimer's disease: studies with auditory moving window presentation. J Gerontol B Psychol Sci Soc Sci. 2002 Jul;57(4):P298-311.

Araria-Goumidi L, Lambert JC, Mann DM, Lendon C, Frigard B, Iwatsubo T, Cottel D, Amouyel P, Chartier-Harlin MC. Association study of three polymorphisms of TGF-beta1 gene with Alzheimer's disease. J Neurol Neurosurg Psychiatry. 2002 Jul;73(1):62-64. ,

Gordon DJ, Tappe R, Meredith SC. Design and characterization of a membrane permeable N-methyl amino acid-containing peptide that inhibits Abeta1-40 fibrillogenesis. J Pept Res. 2002 Jul;60(1):37-55.

Mahoney DF, Tarlow BJ, Jones RN, Sandaire J. Effects of a Multimedia Project on Users' Knowledge about Normal Forgetting and Serious Memory Loss. J Am Med Inform Assoc. 2002 Jul-Aug;9(4):383-94.

Owens CT. Estrogen replacement therapy for Alzheimer disease in postmenopausal women. Ann Pharmacother. 2002 Jul;36(7):1273-6.

Lütjohann D, Brzezinka A, Barth E, Abramowski D, Staufenbiel M, von Bergmann K, Beyreuther K, Multhaup G, Bayer TA. Profile of cholesterol-related sterols in aged amyloid precursor protein transgenic mouse brain. J Lipid Res. 2002 Jul 1;43(7):1078-85.

 

Schaub RT, Anders D, Golz G, Göhringer K, Hellweg R. Serum nerve growth factor concentration and its role in the preclinical stage of dementia. Am J Psychiatry. 2002 Jul;159(7):1227-9.

Zhao L, Chen Q, Brinton RD. Neuroprotective and neurotrophic efficacy of phytoestrogens in cultured hippocampal neurons. Exp Biol Med (Maywood). 2002 Jul;227(7):509-19.

Luxenberg JS. Review: Selegiline leads to a small short-term improvement in cognition and activities of daily living in Alzheimer disease. ACP J Club. 2002 Jul-Aug;137(1):10.

Rao RR, Halper J, Kisaalita WS. Effects of 60 Hz electromagnetic field exposure on APP695 transcription levels in differentiating human neuroblastoma cells. Bioelectrochemistry. 2002 Jul;57(1):9-15.

Easton A, Ridley RM, Baker HF, Gaffan D. Unilateral lesions of the cholinergic Basal forebrain and fornix in one hemisphere and inferior temporal cortex in the opposite hemisphere produce severe learning impairments in rhesus monkeys. Cereb Cortex. 2002 Jul;12(7):729-36.

Niwa K, Kazama K, Younkin L, Younkin SG, Carlson GA, Iadecola C. Cerebrovascular autoregulation is profoundly impaired in mice overexpressing amyloid precursor protein. Am J Physiol Heart Circ Physiol. 2002 Jul;283(1):H315-23.

Halliday G, Ng T, Rodriguez M, Harding A, Blumbergs P, Evans W, Fabian V, Fryer J, Gonzales M, Harper C, Kalnins R, Masters CL, McLean C, Milder DG, Pamphlett R, Scott G, Tannenberg A, Kril J. Consensus neuropathological diagnosis of common dementia syndromes: testing and standardising the use of multiple diagnostic criteria. Acta Neuropathol (Berl). 2002 Jul;104(1):72-8.

 

Su JH, Kesslak JP, Head E, Cotman CW. Caspase-cleaved amyloid precursor protein and activated caspase-3 are co-localized in the granules of granulovacuolar degeneration in Alzheimer's disease and Down's syndrome brain. Acta Neuropathol (Berl). 2002 Jul;104(1):1-6.

Massi F, Klimov D, Thirumalai D, Straub JE. Charge states rather than propensity for beta-structure determine enhanced fibrillogenesis in wild-type Alzheimer's beta-amyloid peptide compared to E22Q Dutch mutant. Protein Sci. 2002 Jul;11(7):1639-47.

 

Kergoat H, Kergoat MJ, Justino L, Chertkow H, Robillard A, Bergman H. Visual retinocortical function in dementia of the Alzheimer type. Gerontology. 2002 Jul-Aug;48(4):197-203.

Bosworth HB, Siegler IC. Terminal change in cognitive function: an updated review of longitudinal studies. Exp Aging Res. 2002 Jul-Sep;28(3):299-315.

Mattson MP, Chan SL, Duan W. Modification of brain aging and neurodegenerative disorders by genes, diet, and behavior. Physiol Rev. 2002 Jul 1;82(3):637-72.

 

Weksler ME, Relkin N, Turkenich R, LaRusse S, Zhou L, Szabo P. Patients with Alzheimer disease have lower levels of serum anti-amyloid peptide antibodies than healthy elderly individuals. Exp Gerontol. 2002 Jul;37(7):943-8. ,

 

Multhaup G, Scheuermann S, Schlicksupp A, Simons A, Strauss M, Kemmling A, Oehler C, Cappai R, Pipkorn R, Bayer TA. Possible mechanisms of APP-mediated oxidative stress in Alzheimer's disease(1,2). Free Radic Biol Med. 2002 Jul 1;33(1):45-51.

 

Hensel A, Wolf H, Kruggel F, Riedel-Heller SG, Nikolaus C, Arendt T, Gertz HJ. Morphometry of the corpus callosum in patients with questionable and mild dementia. J Neurol Neurosurg Psychiatry. 2002 Jul;73(1):59-61.

Fiscus RR. Involvement of Cyclic GMP and Protein Kinase G in the Regulation of Apoptosis and Survival in Neural Cells. Neurosignals. 2002 Jul-Aug;11(4):175-90.

Peers C. The G. L. Brown Prize Lecture. Hypoxic regulation of ion channel function and expression. Exp Physiol. 2002 Jul;87(4):413-22.

Zhou Z, Relkin N, Ghiso J, Smith JD, Gandy S. Human cerebrospinal fluid apolipoprotein E isoforms are apparently inefficient at complexing with synthetic Alzheimer's amyloid-[beta] peptide (A[beta] 1-40 ) in vitro. Mol Med. 2002 Jul;8(7):376-81.

Bisaglia M, Venezia V, Piccioli P, Stanzione S, Porcile C, Russo C, Mancini F, Milanese C, Schettini G. Acetaminophen protects hippocampal neurons and PC12 cultures from amyloid beta-peptides induced oxidative stress and reduces NF-kappaB activation. Neurochem Int. 2002 Jul;41(1):43-54.

Pérez S, Basile M, Mash D, Mufson E. Galanin receptor over-expression within the amygdala in early Alzheimer's disease: An in vitro autoradiographic analysis. J Chem Neuroanat. 2002 Jul;24(2):109.

Josien H. Recent advances in the development of gamma-secretase inhibitors. Curr Opin Drug Discov Devel. 2002 Jul;5(4):513-25.

 

Staats PS. Pain management and beyond: evolving concepts and treatments involving cyclooxygenase inhibition. J Pain Symptom Manage. 2002 Jul;24(1 Suppl):S4-9.

Choe LH, Dutt MJ, Relkin N, Lee KH. Studies of potential cerebrospinal fluid molecular markers for Alzheimer's disease. Electrophoresis. 2002 Jul;23(14):2247-51.

Felipo V, Butterworth R. Neurobiology of ammonia. Prog Neurobiol. 2002 Jul;67(4):259.

Valla J, Chen K, Berndt JD, Gonzalez-Lima F, Cherry SR, Games D, Reiman EM. Effects of Image Resolution on Autoradiographic Measurements of Posterior Cingulate Activity in PDAPP Mice: Implications for Functional Brain Imaging Studies of Transgenic Mouse Models of Alzheimer's Disease. Neuroimage. 2002 Jul;16(1):1-6.

Bergamaschini L, Donarini C, Rossi E, De Luigi A, Vergani C, Grazia De Simoni M. Heparin attenuates cytotoxic and inflammatory activity of Alzheimer amyloid-beta in vitro. Neurobiol Aging. 2002 Jul-Aug;23(4):531-6.

Scali C, Prosperi C, Bracco L, Piccini C, Baronti R, Ginestroni A, Sorbi S, Pepeu G, Casamenti F. Neutrophils CD11b and fibroblasts PGE(2) are elevated in Alzheimer's disease. Neurobiol Aging. 2002 Jul-Aug;23(4):523-30.

Teunissen CE, de Vente J, Steinbusch HW, De Bruijn C. Biochemical markers related to Alzheimer's dementia in serum and cerebrospinal fluid. Neurobiol Aging. 2002 Jul-Aug;23(4):485-508.

 

Praticò D, Uryu K, Sung S, Tang S, Trojanowski JQ, Lee VM. Aluminum modulates brain amyloidosis through oxidative stress in APP transgenic mice. FASEB J. 2002 Jul 1;16(9):1138-40.

van Horssen J, Kleinnijenhuis J, Maass CN, Rensink AA, Otte-Höller I, David G, van den Heuvel LP, Wesseling P, de Waal RM, Verbeek MM. Accumulation of heparan sulfate proteoglycans in cerebellar senile plaques. Neurobiol Aging. 2002 Jul-Aug;23(4):537-45.

Khachaturian ZS. The challenges of developing and validating molecular and biochemical markers of Alzheimer's disease. Neurobiol Aging. 2002 Jul-Aug;23(4):509-11.

Sweet RA, Panchalingam K, Pettegrew JW, McClure RJ, Hamilton RL, Lopez OL, Kaufer DI, DeKosky ST, Klunk WE. Psychosis in Alzheimer disease: postmortem magnetic resonance spectroscopy evidence of excess neuronal and membrane phospholipid pathology. Neurobiol Aging. 2002 Jul-Aug;23(4):547-53.

Papassotiropoulos A, Hock C. Biochemical markers of Alzheimer's disease: wish and reality. Neurobiol Aging. 2002 Jul-Aug;23(4):513-4.

Vega U, Kishikawa Y, Ricanati E, Friedland RP. Suicide and Alzheimer disease. Am J Geriatr Psychiatry. 2002 Jul-Aug;10(4):484-5.

Bergmann J, Kienzl E, Janetzky B, Preddie E, Jellinger KA. Alternatives to the suspended Alzheimer's disease vaccine. Acta Neuropathol (Berl). 2002 Jul;104(1):111-2.

 

Adamec E, Mohan P, Vonsattel JP, Nixon RA. Calpain activation in neurodegenerative diseases: confocal immunofluorescence study with antibodies specifically recognizing the active form of calpain 2. Acta Neuropathol (Berl). 2002 Jul;104(1):92-104.

Watson R. Neurobiology of Alzheimer's disease. J Adv Nurs. 2002 Jul;39(1):109.

Wong PC, Cai H, Borchelt DR, Price DL. Genetically engineered mouse models of neurodegenerative diseases. Nat Neurosci. 2002 Jul;5(7):633-639.

Hajjar I, Schumpert J, Hirth V, Wieland D, Eleazer GP. The impact of the use of statins on the prevalence of dementia and the progression of cognitive impairment. J Gerontol A Biol Sci Med Sci. 2002 Jul;57(7):M414-8.

 

Kennedy DO, Scholey AB, Tildesley NT, Perry EK, Wesnes KA. Modulation of mood and cognitive performance following acute administration of Melissa officinalis (lemon balm). Pharmacol Biochem Behav. 2002 Jul;72(4):953-64.

Verpillat P, Camuzat A, Hannequin D, Thomas-Anterion C, Puel M, Belliard S, Dubois B, Didic M, Lacomblez L, Moreaud O, Golfier V, Campion D, Brice A, Clerget-Darpoux F. Apolipoprotein E gene in frontotemporal dementia: an association study and meta-analysis. Eur J Hum Genet. 2002 Jul;10(7):399-405.

Sigurdsson EM, Brown DR, Daniels M, Kascsak RJ, Kascsak R, Carp R, Meeker HC, Frangione B, Wisniewski T. Immunization delays the onset of prion disease in mice. Am J Pathol. 2002 Jul;161(1):13-7.

 

Lin WR, Wozniak MA, Cooper RJ, Wilcock GK, Itzhaki RF. Herpesviruses in brain and Alzheimer's disease. J Pathol. 2002 Jul 1;197(3):395-402.

Lott IT, Osann K, Doran E, Nelson L. Down syndrome and Alzheimer disease: response to donepezil. Arch Neurol. 2002 Jul;59(7):1133-6.

Meguro K, Ishii H, Yamaguchi S, Ishizaki J, Shimada M, Sato M, Hashimoto R, Shimada Y, Meguro M, Yamadori A, Sekita Y. Prevalence of dementia and dementing diseases in Japan: the Tajiri project. Arch Neurol. 2002 Jul;59(7):1109-14.

Leverenz JB, Agustin CM, Tsuang D, Peskind ER, Edland SD, Nochlin D, DiGiacomo L, Bowen JD, McCormick WC, Teri L, Raskind MA, Kukull WA, Larson EB. Clinical and neuropathological characteristics of hippocampal sclerosis: a community-based study. Arch Neurol. 2002 Jul;59(7):1099-106.

Staessen JA, Wang JG, Thijs L. Calcium-channel blockade and cardiovascular prognosis: recent evidence from clinical outcome trials. Am J Hypertens. 2002 Jul;15(7 Pt 2):85S-93S.

Dominguez DI, Strooper BD. Novel therapeutic strategies provide the real test for the amyloid hypothesis of Alzheimer's disease. Trends Pharmacol Sci. 2002 Jul;23(7):324-30.

Gluck MR, Thomas RG, Davis KL, Haroutunian V. Implications for Altered Glutamate and GABA Metabolism in the Dorsolateral Prefrontal Cortex of Aged Schizophrenic Patients. Am J Psychiatry. 2002 Jul;159(7):1165-73.

Frölich L. The cholinergic pathology in Alzheimer's disease - discrepancies between clinical experience and pathophysiological findings. J Neural Transm. 2002 Jul;109(7-8):1003-13.

Hoyer S. The aging brain. Changes in the neuronal insulin/insulin receptor signal transduction cascade trigger late-onset sporadic Alzheimer disease (SAD). A mini-review. J Neural Transm. 2002 Jul;109(7-8):991-1002.

Tanaka S, Takehashi M, Matoh N, Iida S, Suzuki T, Futaki S, Hamada H, Masliah E, Sugiura Y, Ueda K. Generation of reactive oxygen species and activation of NF-kappaB by non-Abeta component of Alzheimer's disease amyloid. J Neurochem. 2002 Jul;82(2):305-15.

Galvan V, Chen S, Lu D, Logvinova A, Goldsmith P, Koo EH, Bredesen DE. Caspase cleavage of members of the amyloid precursor family of proteins. J Neurochem. 2002 Jul;82(2):283-94.

Matsumoto Y, Watanabe S, Suh YH, Yamamoto T. Effects of intrahippocampal CT105, a carboxyl terminal fragment of beta-amyloid precursor protein, alone/with inflammatory cytokines on working memory in rats. J Neurochem. 2002 Jul;82(2):234-9.

Díaz-Nido J, Wandosell F, Avila J. Glycosaminoglycans and beta-amyloid, prion and tau peptides in neurodegenerative diseases. Peptides. 2002 Jul 1;23(7):1323-32.

 

Butterfield DA, Kanski J. Methionine residue 35 is critical for the oxidative stress and neurotoxic properties of Alzheimer's amyloid beta-peptide 1-42. Peptides. 2002 Jul;23(7):1299-309.

Evin G, Weidemann A. Biogenesis and metabolism of Alzheimer's disease Abeta amyloid peptides. Peptides. 2002 Jul;23(7):1285-97.

Tran MH, Yamada K, Nabeshima T. Amyloid beta-peptide induces cholinergic dysfunction and cognitive deficits: a minireview. Peptides. 2002 Jul;23(7):1271-83.

Parbhu A, Lin H, Thimm J, Lal R. Imaging real-time aggregation of amyloid beta protein (1-42) by atomic force microscopy. Peptides. 2002 Jul;23(7):1265-70.

Morgan C, Bugueño MP, Garrido J, Inestrosa NC. Laminin affects polymerization, depolymerization and neurotoxicity of Abeta peptide. Peptides. 2002 Jul;23(7):1229-40.

Lin MC, Kagan BL. Electrophysiologic properties of channels induced by Abeta25-35 in planar lipid bilayers. Peptides. 2002 Jul 1;23(7):1215-28.

Kienlen-Campard P, Octave JN. Correlation between beta-amyloid peptide production and human APP-induced neuronal death. Peptides. 2002 Jul;23(7):1199-204.

Rottkamp CA, Atwood CS, Joseph JA, Nunomura A, Perry G, Smith MA. The state versus amyloid-beta: the trial of the most wanted criminal in Alzheimer disease. Peptides. 2002 Jul;23(7):1333-41.

 

Bliwise DL. Sleep apnea, APOE4 and Alzheimer's disease 20 years and counting? J Psychosom Res. 2002 Jul;53(1):539-46.

Arlt S, Kontush A, Zerr I, Buhmann C, Jacobi C, Schröter A, Poser S, Beisiegel U. Increased lipid peroxidation in cerebrospinal fluid and plasma from patients with creutzfeldt-jakob disease. Neurobiol Dis. 2002 Jul;10(2):150-6.

 

Gu G, Reyes PE, Golden GT, Woltjer RL, Hulette C, Montine TJ, Zhang J. Mitochondrial DNA deletions/rearrangements in parkinson disease and related neurodegenerative disorders. J Neuropathol Exp Neurol. 2002 Jul;61(7):634-9.

Crowther DC. Familial conformational diseases and dementias. Hum Mutat. 2002 Jul;20(1):1-14.

Goldman JS, Reed B, Gearhart R, Kramer JH, Miller BL. Very early-onset familial Alzheimer's disease: a novel presenilin 1 mutation. Int J Geriatr Psychiatry. 2002 Jul 1;17(7):649-51.

Grossi D, Fragassi NA, Chiacchio L, Valoroso L, Tuccillo R, Perrotta C, Rapone P, Conchiglia G, Trojano L. Do visuospatial and constructional disturbances differentiate frontal variant of frontotemporal dementia and Alzheimer's disease? An experimental study of a clinical belief. Int J Geriatr Psychiatry. 2002 Jul;17(7):641-8.

van der Flier WM, Van Den Heuvel DM, Weverling-Rijnsburger AW, Bollen EL, Westendorp RG, van Buchem MA, Middelkoop HA. Magnetization transfer imaging in normal aging, mild cognitive impairment, and Alzheimer's disease. Ann Neurol. 2002 Jul;52(1):62-7.

Chauhan NB, Siegel GJ. Reversal of amyloid beta toxicity in Alzheimer's disease model Tg2576 by intraventricular antiamyloid beta antibody. J Neurosci Res. 2002 Jul 1;69(1):10-23.

 

Molina JA, Jiménez-Jiménez FJ, Hernánz A, Fernández-Vivancos E, Medina S, de Bustos F, Gómez-Escalonilla C, Sayed Y. Cerebrospinal fluid levels of thiamine in patients with Alzheimer's disease. J Neural Transm. 2002 Jul;109(7-8):1035-44.

Majores M, Kölsch H, Bagli M, Ptok U, Kockler M, Becker K, Rao ML, Maier W, Heun R. The insulin gene VNTR polymorphism in Alzheimer's disease: results of a pilot study. J Neural Transm. 2002 Jul;109(7-8):1029-34. ,

Callen DJ, Black SE, Caldwell CB. Limbic system perfusion in Alzheimer's disease measured by MRI-coregistered HMPAO SPET. Eur J Nucl Med Mol Imaging. 2002 Jul;29(7):899-906.

Lyddy F. Sniffing out a link with Alzheimer's. Trends Cogn Sci. 2002 Jul 1;6(7):280.

Kim SH, Shim KS, Lubec G. Human brain nascent polypeptide-associated complex alpha subunit is decreased in patients with Alzheimer' s disease and Down syndrome. J Investig Med. 2002 Jul;50(4):293-301.

Grace J, Cahn-Weiner D. Behavioral issues in Alzheimer's disease. Med Health R I. 2002 Jul;85(7):213-5.

Ott BR. Medical treatment of Alzheimer's disease: past, present, and future. Med Health R I. 2002 Jul;85(7):210-2.

Besdine RW. Alzheimer's disease in RI: perspectives in 2002. Med Health R I. 2002 Jul;85(7):200-1.

Danysz W. CX-516 cortex pharmaceuticals. Curr Opin Investig Drugs. 2002 Jul;3(7):1081-8.

Müller N, Guendouzi JA. Transcribing discourse: interactions with Alzheimer's disease. Clin Linguist Phon. 2002 Jul-Aug;16(5):345-59.

Xu G, Gonzales V, Borchelt DR. Abeta deposition does not cause the aggregation of endogenous tau in transgenic mice. Alzheimer Dis Assoc Disord. 2002 Jul-Sep;16(3):196-201.

Chapman SB, Zientz J, Weiner M, Rosenberg R, Frawley W, Burns MH. Discourse changes in early Alzheimer disease, mild cognitive impairment, and normal aging. Alzheimer Dis Assoc Disord. 2002 Jul-Sep;16(3):177-86.

Bigler ED, Kerr B, Victoroff J, Tate DF, Breitner JC. White matter lesions, quantitative magnetic resonance imaging, and dementia. Alzheimer Dis Assoc Disord. 2002 Jul-Sep;16(3):161-70.

Bergman M, Salman H, Beloosesky Y, Djaldetti M, Bessler H. Are peripheral blood cells from patients with Alzheimer disease more sensitive to apoptotic stimuli? Alzheimer Dis Assoc Disord. 2002 Jul-Sep;16(3):156-60.

Borroni B, Volpi R, Martini G, Del Bono R, Archetti S, Colciaghi F, Akkawi NM, Di Luca M, Romanelli G, Caimi L, Padovani A. Peripheral blood abnormalities in Alzheimer disease: evidence for early endothelial dysfunction. Alzheimer Dis Assoc Disord. 2002 Jul-Sep;16(3):150-5.

Csernansky JG, Miller JP, McKeel D, Morris JC. Relationships among cerebrospinal fluid biomarkers in dementia of the Alzheimer type. Alzheimer Dis Assoc Disord. 2002 Jul-Sep;16(3):144-9. ,

Sloan FA, Taylor Jr DH. Effect of Alzheimer disease on the cost of treating other diseases. Alzheimer Dis Assoc Disord. 2002 Jul-Sep;16(3):137-43.

Crisby M, Carlson LA, Winblad B. Statins in the prevention and treatment of Alzheimer disease. Alzheimer Dis Assoc Disord. 2002 Jul-Sep;16(3):131-6.

Sharma JC. Cholinesterase inhibitors in Alzheimer's disease: donepezil or rivastigmine? Int J Clin Pract. 2002 Jul-Aug;56(6):414-5.

Kuperstein F, Yavin E. ERK activation and nuclear translocation in amyloid-beta peptide- and iron-stressed neuronal cell cultures. Eur J Neurosci. 2002 Jul;16(1):44-54.

Foster H. Why the preeminent risk factor in sporadic Alzheimer's disease cannot be genetic. Med Hypotheses. 2002 Jul;59(1):57.

Maher L. More than memory. The ancient art of storytelling can liberate the voices and imaginations of those with Alzheimer's disease. Contemp Longterm Care. 2002 Jul;25(7):16-8.

Grigorenko AP, Moliaka YK, Korovaitseva GI, Rogaev EI. Novel class of polytopic proteins with domains associated with putative protease activity. Biochemistry (Mosc). 2002 Jul;67(7):826-35.

Rigaud AS, Traykov L, Latour F, Couderc R, Moulin F, Forette F. Presence or absence of at least one &epsis;4 allele and gender are not predictive for the response to donepezil treatment in Alzheimer's disease. Pharmacogenetics. 2002 Jul;12(5):415-420.

Revesz T, Holton JL, Lashley T, Plant G, Rostagno A, Ghiso J, Frangione B. Sporadic and familial cerebral amyloid angiopathies. Brain Pathol. 2002 Jul;12(3):343-57.

Riello R, Geroldi C, Parrinello G, Frisoni GB. The relationship between biological and environmental determinants of delusions in mild Alzheimer's disease patients. Int J Geriatr Psychiatry. 2002 Jul;17(7):687-688.

Lee YB, Nagai A, Kim SU. Cytokines, chemokines, and cytokine receptors in human microglia. J Neurosci Res. 2002 Jul 1;69(1):94-103.

Münch G, Robinson SR. Potential neurotoxic inflammatory responses to Abeta vaccination in humans. J Neural Transm. 2002 Jul;109(7-8):1081-7.

 

Araria-Goumidi L, Huguet JB, Lambert JC, Frigard B, Cottel D, Amouyel P, Chartier-Harlin MC. No association of the -48CT polymorphism of the presenilin 1 gene with Alzheimer disease in a late-onset sporadic population. J Neural Transm. 2002 Jul;109(7-8):1023-7. ,

Sangha SS, Uber PA, Park MH, Scott RL, Mehra MR. Difficult cases in heart failure: The challenge of neurocognitive dysfunction in severe heart failure. Congest Heart Fail. 2002 Jul-Aug;8(4):232-4.

Woulfe JM, Hammond R, Richardson B, Sooriabalan D, Parks W, Rippstein P, Munoz DG. Reduction of neuronal intranuclear rodlets immunoreactive for tubulin and glucocorticoid receptor in Alzheimer's disease. Brain Pathol. 2002 Jul;12(3):300-7.

Wirths O, Multhaup G, Czech C, Feldmann N, Blanchard V, Tremp G, Beyreuther K, Pradier L, Bayer TA. Intraneuronal APP/A beta trafficking and plaque formation in beta-amyloid precursor protein and presenilin-1 transgenic mice. Brain Pathol. 2002 Jul 1;12(3):275-86.

Bondi MW, Serody AB, Chan AS, Eberson-Shumate SC, Delis DC, Hansen LA, Salmon DP. Cognitive and neuropathologic correlates of Stroop Color-Word Test performance in Alzheimer's disease. Neuropsychology. 2002 Jul;16(3):335-43.

Bronge L. Magnetic resonance imaging in dementia. A study of brain white matter changes. Acta Radiol Suppl. 2002 Jul;(428):1-32.

Arias C, Montiel T, Quiroz-Báez R, Massieu L. beta-Amyloid Neurotoxicity Is Exacerbated during Glycolysis Inhibition and Mitochondrial Impairment in the Rat Hippocampus in Vivo and in Isolated Nerve Terminals: Implications for Alzheimer's Disease. Exp Neurol. 2002 Jul;176(1):163-74.

 

Carta MG, Serra P, Ghiani A, Manca E, Hardoy MC, Del Giacco GS, Diaz G, Carpiniello B, Manconi PE. Chemokines and Pro-Inflammatory Cytokines in Down's Syndrome: An Early Marker for Alzheimer-Type Dementia? Psychother Psychosom. 2002 Jul-Aug;71(4):233-6.