2002: December: Alzheimer’s Research Papers
Monastero R, Caldarella R, Mannino M, Cefalù AB, Lopez G, Noto D, Camarda C, Camarda LK, Notarbartolo A, Averna MR, Camarda R. Lack of association between angiotensin converting enzyme polymorphism and sporadic Alzheimer's disease. Neurosci Lett. 2002 Dec 25;335(2):147-9. ,
Boccardi M, Pennanen C, Laakso MP, Testa C, Geroldi C, Soininen H, Frisoni GB. Amygdaloid atrophy in frontotemporal dementia and Alzheimer's disease. Neurosci Lett. 2002 Dec 25;335(2):139-43.
Araria-Goumidi L, Lambert JC, Cottel D, Amouyel P, Chartier-Harlin MC. No association of the HLA-A2 allele with Alzheimer's disease. Neurosci Lett. 2002 Dec 25;335(2):75-8. ,
Petkova AT, Ishii Y, Balbach JJ, Antzutkin ON, Leapman RD, Delaglio F, Tycko R. A structural model for Alzheimer's beta -amyloid fibrils based on experimental constraints from solid state NMR. Proc Natl Acad Sci U S A. 2002 Dec 24;99(26):16742-7.
Antzutkin ON, Leapman RD, Balbach JJ, Tycko R. Supramolecular structural constraints on Alzheimer's beta-amyloid fibrils from electron microscopy and solid-state nuclear magnetic resonance. Biochemistry. 2002 Dec 24;41(51):15436-50.
Giasson BI, Sampathu DM, Wilson CA, Vogelsberg-Ragaglia V, Mushynski WE, Lee VM. The environmental toxin arsenite induces tau hyperphosphorylation. Biochemistry. 2002 Dec 24;41(51):15376-87.
Betts R, Weinsheimer S, Blouse G, Anagli J. Structural determinants of the calpain inhibitory activity of calpastatin peptide B27-WT. J Biol Chem. 2002 Dec 24;
Chang RC, Wong AK, Ng HK, Hugon J. Phosphorylation of eukaryotic initiation factor-2alpha (eIF2alpha) is associated with neuronal degeneration in Alzheimer's disease. Neuroreport. 2002 Dec 20;13(18):2429-32.
Reiser G, Bernstein HG. Neurons and plaques of Alzheimer's disease patients highly express the neuronal membrane docking protein p42IP4/centaurin alpha. Neuroreport. 2002 Dec 20;13(18):2417-9.
Kim DY, Ingano LA, Kovacs DM. Nectin-1alpha, an immunoglobulin-like receptor involved in the formation of synapses, is a substrate for presenilin/gamma-secretase-like cleavage. J Biol Chem. 2002 Dec 20;277(51):49976-81.
Rostagno A, Revesz T, Lashley T, Tomidokoro Y, Magnotti L, Braendgaard H, Plant G, Bojsen-Moller M, Holton J, Frangione B, Ghiso J. Complement Activation in Chromosome 13 Dementias. SIMILARITIES WITH ALZHEIMER'S DISEASE. J Biol Chem. 2002 Dec 20;277(51):49782-49790.
Tales A, Muir JL, Bayer A, Jones R, Snowden RJ. Phasic visual alertness in Alzheimer's disease and ageing. Neuroreport. 2002 Dec 20;13(18):2557-60.
Takasugi N, Takahashi Y, Morohashi Y, Tomita T, Iwatsubo T. The Mechanism of gamma -Secretase Activities through High Molecular Weight Complex Formation of Presenilins Is Conserved in Drosophila melanogaster and Mammals. J Biol Chem. 2002 Dec 20;277(51):50198-205.
Naidu A, Xu Q, Catalano R, Cordell B. Secretion of apolipoprotein E by brain glia requires protein prenylation and is suppressed by statins. Brain Res. 2002 Dec 20;958(1):100-11.
Miguel-Hidalgo JJ, Alvarez XA, Cacabelos R, Quack G. Neuroprotection by memantine against neurodegeneration induced by beta-amyloid(1-40). Brain Res. 2002 Dec 20;958(1):210-21.
Wu B, Kitagawa K, Yagyu K, Zhang NY
Haasdijk ED, Vlug A, Mulder MT, Jaarsma D. Increased apolipoprotein E expression correlates with the onset of neuronal degeneration in the spinal cord of G93A-SOD1 mice. Neurosci Lett. 2002 Dec 19;335(1):29-33.
Ikeuchi T, Dolios G, Kim SH, Wang R, Sisodia SS. Familial Alzheimer disease-linked presenilin 1 variants enhance production of both Abeta 1-40 and Abeta 1-42 peptides that are only partially sensitive to a potent aspartyl protease transition-state inhibitor of "gamma -secretase" J Biol Chem. 2002 Dec 19;
Kwok JB, Halliday GM, Brooks WS, Dolios G, Laudon H, Murayama O, Hallupp M, Badenhop RF, Vickers J, Wang R, Naslund J, Takashima A, Gandy SE, Schofield PR. Presenilin-1 mutation (Leu271VAL) results in altered exon 8 splicing and Alzheimer's disease with non-coded plaques and NO neuritic dystrophy. J Biol Chem. 2002 Dec 19;
Barghorn S, Mandelkow E. Toward a unified scheme for the aggregation of tau into Alzheimer paired helical filaments. Biochemistry. 2002 Dec 17;41(50):14885-96.
MacIntyre A, Hammond CJ, Little CS, Appelt DM, Balin BJ. Chlamydia pneumoniae infection alters the junctional complex proteins of human brain microvascular endothelial cells. FEMS Microbiol Lett. 2002 Dec 17;217(2):167-72.
Yoo BC, Krapfenbauer K, Cairns N, Belay G, Bajo M, Lubec G. Overexpressed protein disulfide isomerase in brains of patients with sporadic Creutzfeldt-Jakob disease. Neurosci Lett. 2002 Dec 16;334(3):196-200.
Burton TR, Dibrov A, Kashour T, Amara FM. Anti-apoptotic wild-type Alzheimer amyloid precursor protein signaling involves the p38 mitogen-activated protein kinase/MEF2 pathway. Brain Res Mol Brain Res. 2002 Dec 16;108(1-2):102-20.
Shea TB, Rogers E. Folate quenches oxidative damage in brains of apolipoprotein E-deficient mice: augmentation by vitamin E. Brain Res Mol Brain Res. 2002 Dec 16;108(1-2):1-6.
Deininger MH, Fimmen BA, Thal DR, Schluesener HJ, Meyermann R. Aberrant neuronal and paracellular deposition of endostatin in brains of patients with Alzheimer's disease. J Neurosci. 2002 Dec 15;22(24):10621-6.
Tomasiewicz HG, Flaherty DB, Soria JP, Wood JG. Transgenic zebrafish model of neurodegeneration. J Neurosci Res. 2002 Dec 15;70(6):734-45.
Yamamoto H, Yamauchi E, Taniguchi H, Ono T, Miyamoto E. Phosphorylation of microtubule-associated protein tau by Ca2+/calmodulin-dependent protein kinase II in its tubulin binding sites. Arch Biochem Biophys. 2002 Dec 15;408(2):255-62.
Buttini M, Yu GQ, Shockley K, Huang Y, Jones B, Masliah E, Mallory M, Yeo T, Longo FM, Mucke L. Modulation of Alzheimer-like synaptic and cholinergic deficits in transgenic mice by human apolipoprotein E depends on isoform, aging, and overexpression of amyloid beta peptides but not on plaque formation. J Neurosci. 2002 Dec 15;22(24):10539-48. ,
Burns A, Zaudig M. Mild cognitive impairment in older people. Lancet. 2002 Dec 14;360(9349):1963-5.
Wulf GM, Liou YC, Ryo A, Lee SW, Lu KP. Role of Pin1 in the regulation of p53 stability and p21 transactivation, and cell cycle checkpoints in response to DNA damage. J Biol Chem. 2002 Dec 13;277(50):47976-9.
Fukumoto H, Deng A, Irizarry MC, Fitzgerald ML, Rebeck GW. Induction of the Cholesterol Transporter ABCA1 in Central Nervous System Cells by Liver X Receptor Agonists Increases Secreted Abeta Levels. J Biol Chem. 2002 Dec 13;277(50):48508-13.
Xu X, Shi YC, Gao W, Mao G, Zhao G, Agrawal S, Chisolm GM, Sui D, Cui MZ. The Novel Presenilin-1-associated Protein Is a Proapoptotic Mitochondrial Protein. J Biol Chem. 2002 Dec 13;277(50):48913-48922.
Spooner ET, Desai RV, Mori C, Leverone JF, Lemere CA
Nakagami Y, Nishimura S, Murasugi T, Kubo T, Kaneko I, Meguro M, Marumoto S, Kogen H, Koyama K, Oda T. A novel compound RS-0466 reverses beta-amyloid-induced cytotoxicity through the Akt signaling pathway in vitro. Eur J Pharmacol. 2002 Dec 13;457(1):11-7.
Olariu A, Yamada K, Mamiya T, Hefco V, Nabeshima T. Memory impairment induced by chronic intracerebroventricular infusion of beta-amyloid (1-40) involves downregulation of protein kinase C. Brain Res. 2002 Dec 13;957(2):278-86.
Ohkawa H, Sohma H, Sakai R, Kuroki Y, Hashimoto E, Murakami S, Saito T. Ethanol-induced augmentation of annexin IV in cultured cells and the enhancement of cytotoxicity by overexpression of annexin IV by ethanol. Biochim Biophys Acta. 2002 Dec 12;1588(3):217-25.
McClintock KA, Shaw GS. A novel S100 target conformation is revealed by the solution structure of the Ca2+-S100B-TRTK-12 complex. J Biol Chem. 2002 Dec 11;
Lopez De La Paz M, Goldie K, Zurdo J, Lacroix E, Dobson CM, Hoenger A, Serrano L. De novo designed peptide-based amyloid fibrils. Proc Natl Acad Sci U S A. 2002 Dec 10;99(25):16052-7.
Cao Q, Jiang K, Liu Y, Zhang M, Xiao S, Zuo C, Huang H. [The comparison of the regional cerebral metabolism rate of glucose in Alzheimer's disease with mild cognitive impairment] Zhonghua Yi Xue Za Zhi. 2002 Dec 10;82(23):1613-6.
Kitazume S, Tachida Y, Oka R, Kotani N, Ogawa K, Suzuki M, Dohmae N, Takio K, Saido TC, Hashimoto Y. Characterization of alpha 2,6-sialyltransferase cleavage by Alzheimer's beta -secretase(BACE1). J Biol Chem. 2002 Dec 7;
Roberts SB. gamma-Secretase inhibitors and Alzheimer's disease. Adv Drug Deliv Rev. 2002 Dec 7;54(12):1579-88.
Ghiso J, Frangione B. Amyloidosis and Alzheimer's disease. Adv Drug Deliv Rev. 2002 Dec 7;54(12):1539-51.
Moore AH, O'Banion MK. Neuroinflammation and anti-inflammatory therapy for Alzheimer's disease. Adv Drug Deliv Rev. 2002 Dec 7;54(12):1627-56.
Holtzman DM, Bales KR, Paul SM, DeMattos RB. Abeta immunization and anti-Abeta antibodies: potential therapies for the prevention and treatment of Alzheimer's disease. Adv Drug Deliv Rev. 2002 Dec 7;54(12):1603-13.
Vassar R. beta-Secretase (BACE) as a drug target for alzheimer's disease. Adv Drug Deliv Rev. 2002 Dec 7;54(12):1589-602.
Tariot PN, Loy R, Ryan JM, Porsteinsson A, Ismail S. Mood stabilizers in Alzheimer's disease: symptomatic and neuroprotective rationales. Adv Drug Deliv Rev. 2002 Dec 7;54(12):1567-77.
Small GW. Use of neuroimaging to detect early brain changes in people at genetic risk for Alzheimer's disease. Adv Drug Deliv Rev. 2002 Dec 7;54(12):1561-6.
Zlokovic BV. Vascular disorder in Alzheimer's disease: role in pathogenesis of dementia and therapeutic targets. Adv Drug Deliv Rev. 2002 Dec 7;54(12):1553-9.
Zlokovic BV. Alzheimer's disease (AD) has been classified and treated as a neurodegenerative disorder. Adv Drug Deliv Rev. 2002 Dec 7;54(12):1533-7.
Tyler SJ, Dawbarn D, Wilcock GK, Allen SJ. alpha- and beta-secretase: profound changes in Alzheimer's disease. Biochem Biophys Res Commun. 2002 Dec 6;299(3):373-6.
Hong HN, Yoon SY, Suh J, Lee JH, Kim D. Differential activation of caspase-3 at two maturational stages during okadaic acid-induced rat neuronal death. Neurosci Lett. 2002 Dec 6;334(1):63-7.
Kohler J, Riepe MW, Jendroska K, Pilartz H, Adler G, Berger FM, Calabrese P, Frölich L, Gertz HJ, Hampel H, Haupt M, Mielke R, Paulus HJ, Zedlick D. [Early diagnosis and treatment of Alzheimer's disease. Implementation in the doctor's office] Fortschr Med Orig. 2002 Dec 5;120(4):135-41.
Yoshiura T, Mihara F, Ogomori K, Tanaka A, Kaneko K, Masuda K. Diffusion tensor in posterior cingulate gyrus: correlation with cognitive decline in Alzheimer's disease. Neuroreport. 2002 Dec 3;13(17):2299-302.
Tschäpe JA, Hammerschmied C, Mühlig-Versen M, Athenstaedt K, Daum G, Kretzschmar D. The neurodegeneration mutant löchrig interferes with cholesterol homeostasis and Appl processing. EMBO J. 2002 Dec 2;21(23):6367-76.
Nelson JS. Alzheimer pathology in elderly patients with glioblastoma multiforme. Arch Pathol Lab Med. 2002 Dec;126(12):1515-7.
Devous Sr MD. Functional brain imaging in the dementias: role in early detection, differential diagnosis, and longitudinal studies. Eur J Nucl Med Mol Imaging. 2002 Dec;29(12):1685-96.
Chong YH, Shin SA, Lee HJ, Kang JH, Suh YH. Molecular mechanisms underlying cyclic AMP inhibition of macrophage dependent TNF-alpha production and neurotoxicity in response to amyloidogenic C-terminal fragment of Alzheimer's amyloid precursor protein. J Neuroimmunol. 2002 Dec;133(1-2):160-74.
Ferrer I. Differential expression of phosphorylated translation initiation factor 2 alpha in Alzheimer's disease and Creutzfeldt-Jakob's disease. Neuropathol Appl Neurobiol. 2002 Dec;28(6):441-51.
Rösler A, Seifritz E, Kräuchi K, Spoerl D, Brokuslaus I, Proserpi SM, Gendre A, Savaskan E, Hofmann M. Skill learning in patients with moderate Alzheimer's disease: a prospective pilot-study of waltz-lessons. Int J Geriatr Psychiatry. 2002 Dec;17(12):1155-6.
Shimada A, Keino H, Satoh M, Kishikawa M, Seriu N, Hosokawa M. Age-related progressive neuronal DNA damage associated with cerebral degeneration in a mouse model of accelerated senescence. J Gerontol A Biol Sci Med Sci. 2002 Dec;57(12):B415-21.
Polidori MC, Mecocci P. Plasma susceptibility to free radical-induced antioxidant consumption and lipid peroxidation is increased in very old subjects with Alzheimer disease. J Alzheimers Dis. 2002 Dec;4(6):517-522.
Checler F, Vincent B. Alzheimer's and prion diseases: distinct pathologies, common proteolytic denominators. Trends Neurosci. 2002 Dec;25(12):616-20.
Perry G, Taddeo MA, Nunomura A, Zhu X, Zenteno-Savin T, Drew KL, Shimohama S, Avila J, Castellani RJ, Smith MA. Comparative biology and pathology of oxidative stress in Alzheimer and other neurodegenerative diseases: beyond damage and response. Comp Biochem Physiol C Toxicol Pharmacol. 2002 Dec 1;133(4):507-13.
Perry G, Nunomura A, Hirai K, Zhu X, Prez M, Avila J, Castellani RJ, Atwood CS, Aliev G, Sayre LM, Takeda A, Smith MA. Is oxidative damage the fundamental pathogenic mechanism of Alzheimer's and other neurodegenerative diseases? Free Radic Biol Med. 2002 Dec 1;33(11):1475-9.
Serfaty M, Kennell-Webb S, Warner J, Blizard R, Raven P. Double blind randomised placebo controlled trial of low dose melatonin for sleep disorders in dementia. Int J Geriatr Psychiatry. 2002 Dec;17(12):1120-7.
Molina JA, Jiménez-Jiménez FJ, Vargas C, Gómez P, de Bustos F, Gómez-Escalonilla C, Zurdo M, Tallón A, Martínez-Salio A, Porta-Etessam J, Villanueva C, Arenas J. Cerebrospinal fluid levels of insulin in patients with Alzheimer's disease. Acta Neurol Scand. 2002 Dec;106(6):347-50.
Kuikka JT. Fractal analysis of cerebral blood flow distribution in Alzheimer's disease. J Nucl Med. 2002 Dec;43(12):1727-8;
Mulder C, Schoonenboom SN, Wahlund LO, Scheltens P, Van Kamp GJ, Veerhuis R, Hack CE, Blomberg M, Schutgens RB, Eikelenboom P. CSF markers related to pathogenetic mechanisms in Alzheimer's disease. J Neural Transm. 2002 Dec;109(12):1491-8. ,
Prasad KN, Cole WC, Prasad KC. Risk factors for Alzheimer's disease: role of multiple antioxidants, non-steroidal anti-inflammatory and cholinergic agents alone or in combination in prevention and treatment. J Am Coll Nutr. 2002 Dec;21(6):506-22.
Rosen AC, Bokde AL, Pearl A, Yesavage JA. Ethical, and practical issues in applying functional imaging to the clinical management of Alzheimer's disease. Brain Cogn. 2002 Dec;50(3):498-519.
Hernández F, Borrell J, Guaza C, Avila J, Lucas JJ. Spatial learning deficit in transgenic mice that conditionally over-express GSK-3beta in the brain but do not form tau filaments. J Neurochem. 2002 Dec 1;83(6):1529-33.
McGeer PL, McGeer EG. Local neuroinflammation and the progression of Alzheimer's disease. J Neurovirol. 2002 Dec;8(6):529-38.
O'Keefe GM, Nguyen VT, Benveniste EN. Regulation and function of class II major histocompatibility complex, CD40, and B7 expression in macrophages and microglia: Implications in neurological diseases. J Neurovirol. 2002 Dec;8(6):496-512.
Hamdane M, Smet C, Sambo AV, Leroy A, Wieruszeski JM, Delobel P, Maurage CA, Ghestem A, Wintjens R, Bégard S, Sergeant N, Delacourte A, Horvath D, Landrieu I, Lippens G, Buée L. Pin1: a therapeutic target in Alzheimer neurodegeneration. J Mol Neurosci. 2002 Dec;19(3):275-87.
Small GW, Agdeppa ED, Kepe V, Satyamurthy N, Huang SC, Barrio JR. In vivo brain imaging of tangle burden in humans. J Mol Neurosci. 2002 Dec;19(3):323-7.
Dalrymple SA. p38 mitogen activated protein kinase as a therapeutic target for Alzheimer's disease. J Mol Neurosci. 2002 Dec;19(3):295-9.
Lau LF, Seymour PA, Sanner MA, Schachter JB. Cdk5 as a drug target for the treatment of Alzheimer's disease. J Mol Neurosci. 2002 Dec;19(3):267-73.
Gozes I. Tau as a drug target in Alzheimer's disease. J Mol Neurosci. 2002 Dec;19(3):337-8.
Duff K, Noble W, Gaynor K, Matsuoka Y. Organotypic slice cultures from transgenic mice as disease model systems. J Mol Neurosci. 2002 Dec;19(3):317-20.
Ko LW, DeTure M, Sahara N, Chihab R, Yen SH. Cellular models for tau filament assembly. J Mol Neurosci. 2002 Dec;19(3):311-6.
Loy R, Tariot PN. Neuroprotective properties of valproate: potential benefit for AD and tauopathies. J Mol Neurosci. 2002 Dec;19(3):303-7.
Michaelis ML, Dobrowsky RT, Li G. Tau neurofibrillary pathology and microtubule stability. J Mol Neurosci. 2002 Dec;19(3):289-93.
Hall GF, Lee S, Yao J. Neurofibrillary degeneration can be arrested in an in vivo cellular model of human tauopathy by application of a compound which inhibits tau filament formation in vitro. J Mol Neurosci. 2002 Dec;19(3):253-60.
Fillit HM, Refolo LM. Tau and Alzheimer's disease: the long road to anti-tangle therapeutics. J Mol Neurosci. 2002 Dec;19(3):249-50.
Sparks DL, Lochhead J, Horstman D, Wagoner T, Martin T. Water quality has a pronounced effect on cholesterol-induced accumulation of Alzheimer amyloid beta (Abeta) in rabbit brain. J Alzheimers Dis. 2002 Dec;4(6):523-529.
Gold M. Tau therapeutics for Alzheimer's disease: the promise and the challenges. J Mol Neurosci. 2002 Dec;19(3):331-4.
Melo JB, Agostinho P, Oliveira CR. Amyloid beta-peptide 25-35 reduces [3H]acetylcholine release in retinal neurons. Involvement of metabolic dysfunction. Amyloid. 2002 Dec;9(4):221-8.
Silva DW, Damasceno BP. [Dementia in patients of UNICAMP University Hospital] Arq Neuropsiquiatr. 2002 Dec;60(4):996-99.
Pakaski M, Balaspiri L, Checler F, Kasa P. Human amyloid-beta causes changes in the levels of endothelial protein kinase C and its alpha isoform in vitro. Neurochem Int. 2002 Dec;41(6):409.
Söti C, Csermely P. Chaperones and aging: role in neurodegeneration and in other civilizational diseases. Neurochem Int. 2002 Dec;41(6):383.
Welland RJ, Lubinski R, Higginbotham DJ. Discourse comprehension test performance of elders with dementia of the Alzheimer type. J Speech Lang Hear Res. 2002 Dec;45(6):1175-87.
Jolas T, Zhang XS, Zhang Q, Wong G, Vecchio RD, Gold L, Priestley T. Long-Term Potentiation Is Increased in the CA1 Area of the Hippocampus of APP(swe/ind) CRND8 Mice. Neurobiol Dis. 2002 Dec;11(3):394-409.
De Felice FG, Ferreira ST. Beta-amyloid production, aggregation, and clearance as targets for therapy in Alzheimer's disease. Cell Mol Neurobiol. 2002 Dec;22(5-6):545-63.
Hartman RE, Laurer H, Longhi L, Bales KR, Paul SM, McIntosh TK, Holtzman DM. Apolipoprotein E4 influences amyloid deposition but not cell loss after traumatic brain injury in a mouse model of Alzheimer's disease. J Neurosci. 2002 Dec 1;22(23):10083-7.
Barton D, Loprinzi C. Novel approaches to preventing chemotherapy-induced cognitive dysfunction in breast cancer: the art of the possible. Clin Breast Cancer. 2002 Dec;3 Suppl 3:S121-7.
Yagami T, Ueda K, Asakura K, Sakaeda T, Nakazato H, Kuroda T, Hata S, Sakaguchi G, Itoh N, Nakano T, Kambayashi Y, Tsuzuki H. Gas6 rescues cortical neurons from amyloid beta protein-induced apoptosis. Neuropharmacology. 2002 Dec;43(8):1289-96.
Moalem S, Percy ME. The Quandary of Reductionism: Relevance to Alzheimer Disease Research. J Alzheimers Dis. 2002 Dec;4(6):531-537.
Banks WA, Terrell B, Farr SA, Robinson SM, Nonaka N, Morley JE. Passage of amyloid beta protein antibody across the blood-brain barrier in a mouse model of Alzheimer's disease. Peptides. 2002 Dec;23(12):2223-6.
Nonaka N, Banks WA, Mizushima H, Shioda S, Morley JE. Regional differences in PACAP transport across the blood-brain barrier in mice: a possible influence of strain, amyloid beta protein, and age. Peptides. 2002 Dec;23(12):2197-202.
Carro E, Trejo JL, Gomez-Isla T, LeRoith D, Torres-Aleman I. Serum insulin-like growth factor I regulates brain amyloid-beta levels. Nat Med. 2002 Dec 1;8(12):1390-7.
Ferrer I, Barrachina M, Puig B. Anti-tau phospho-specific Ser(262) antibody recognizes a variety of abnormal hyper-phosphorylated tau deposits in tauopathies including Pick bodies and argyrophilic grains. Acta Neuropathol (Berl). 2002 Dec;104(6):658-64.
Yokota O, Terada S, Ishizu H, Ujike H, Ishihara T, Nakashima H, Yasuda M, Kitamura Y, Uéda K, Checler F, Kuroda S. NACP/alpha-Synuclein, NAC, and beta-amyloid pathology of familial Alzheimer's disease with the E184D presenilin-1 mutation: a clinicopathological study of two autopsy cases. Acta Neuropathol (Berl). 2002 Dec;104(6):637-48.
Ferrer I, Barrachina M, Puig B. Glycogen synthase kinase-3 is associated with neuronal and glial hyperphosphorylated tau deposits in Alzheimer's disease, Pick's disease, progressive supranuclear palsy and corticobasal degeneration. Acta Neuropathol (Berl). 2002 Dec;104(6):583-91.
Egan JA, Nugent RP, Filer CN. Tritium labelling and characterization of the cognition enhancing drug tacrine using several precursors. Appl Radiat Isot. 2002 Dec;57(6):837-40.
Tan J, Town T, Crawford F, Mori T, Delledonne A, Crescentini R, Obregon D, Flavell RA, Mullan MJ. Role of CD40 ligand in amyloidosis in transgenic Alzheimer's mice. Nat Neurosci. 2002 Dec 1;5(12):1288-93.
Frisoni GB, Testa C, Zorzan A, Sabattoli F, Beltramello A, Soininen H, Laakso MP. Detection of grey matter loss in mild Alzheimer's disease with voxel based morphometry. J Neurol Neurosurg Psychiatry. 2002 Dec;73(6):657-64.
Chazot PL, Godukhin OV, McDonald A, Obrenovitch TP. Spreading depression-induced preconditioning in the mouse cortex: differential changes in the protein expression of ionotropic nicotinic acetylcholine and glutamate receptors. J Neurochem. 2002 Dec;83(5):1235-8.
Yagyu K, Kitagawa K, Wu B, Zhang NY, Irie T, Hattori N, Inagaki C. Protective effects of estradiol against amyloid beta protein-induced inhibition of neuronal CI(-)-ATPase activity. Neuropharmacology. 2002 Dec;43(8):1297-304.
Erkinjuntti T, Skoog I, Lane R, Andrews C. Rivastigmine in patients with Alzheimer's disease and concurrent hypertension. Int J Clin Pract. 2002 Dec;56(10):791-6.
Benton D. Selenium intake, mood and other aspects of psychological functioning. Nutr Neurosci. 2002 Dec;5(6):363-74.
Guo H, Lai L, Butchbach ME, Lin CG. Human Glioma Cells and Undifferentiated Primary Astrocytes That Express Aberrant EAAT2 mRNA Inhibit Normal EAAT2 Protein Expression and Prevent Cell Death. Mol Cell Neurosci. 2002 Dec;21(4):546-60.
Hu X, Okamura N, Arai H, Higuchi M, Maruyama M, Itoh M, Yamaguchi K, Sasaki H. Neuroanatomical correlates of low body weight in Alzheimer's disease: a PET study. Prog Neuropsychopharmacol Biol Psychiatry. 2002 Dec;26(7-8):1285-9.
Kaneko K, Yoshida K, Arima K, Ohara S, Miyajima H, Kato T, Ohta M, Ikeda SI. Astrocytic deformity and globular structures are characteristic of the brains of patients with aceruloplasminemia. J Neuropathol Exp Neurol. 2002 Dec;61(12):1069-77.
Iwata A, Chen XH, McIntosh TK, Browne KD, Smith D. Long-term accumulation of amyloid-beta in axons following brain trauma without persistent upregulation of amyloid precursor protein genes. J Neuropathol Exp Neurol. 2002 Dec;61(12):1056-68.
Ishizawa T, Ko LW, Cookson N, Davias P, Espinoza M, Dickson DW. Selective neurofibrillary degeneration of the hippocampal CA2 sector is associated with four-repeat tauopathies. J Neuropathol Exp Neurol. 2002 Dec;61(12):1040-7.
Budson AE, Sullivan AL, Mayer E, Daffner KR, Black PM, Schacter DL. Suppression of false recognition in Alzheimer's disease and in patients with frontal lobe lesions. Brain. 2002 Dec;125(Pt 12):2750-65.
Ingram EM, Spillantini MG. Tau gene mutations: dissecting the pathogenesis of FTDP-17. Trends Mol Med. 2002 Dec;8(12):555-62.
Mead JR, Irvine SA, Ramji DP. Lipoprotein lipase: structure, function, regulation, and role in disease. J Mol Med. 2002 Dec;80(12):753-69.
Moalem S, Percy ME. The Quandary of Reductionism: Relevance to Alzheimer disease Research. J Alzheimers Dis. 2002 Dec;4(6):527-33.
Sparks DL, Lochhead J, Horstman D, Wagoner T, Martin T. Water quality has a pronounced effect on cholesterol-induced accumulation of Alzheimer amyloid beta (Abeta) in rabbit brain. J Alzheimers Dis. 2002 Dec 1;4(6):523-9.
Polidori MC, Mecocci P. Plasma susceptibility to free radical-induced antioxidant consumption and lipid peroxidation is increased in very old subjects with Alzheimer disease. J Alzheimers Dis. 2002 Dec;4(6):513-8.
Perry T, Greig NH. The glucagon-like peptides: a new genre in therapeutic targets for intervention in Alzheimer's disease. J Alzheimers Dis. 2002 Dec;4(6):487-96.
Bozner P, Wilson GL, Druzhyna NM, Bryant-Thomas TK, LeDoux SP, Wilson GL, Pappolla MA. Deficiency of chaperonin 60 in Down's syndrome. J Alzheimers Dis. 2002 Dec;4(6):479-86.
Levin-Allerhand JA, Lominska CE, Wang J, Smith JD. 17alpha-estradiol and 17beta-estradiol treatments are effective in lowering cerebral amyloid-beta levels in AbetaPPSWE transgenic mice. J Alzheimers Dis. 2002 Dec;4(6):449-57.
Palotás A, Kálmán J, Palotás M, Matin K, Szentpáli K, Paszt A, Janka Z, Penke B. Whole blood samples from Alzheimer patients and control donors demonstrate fluorimetric differences. Neurochem Res. 2002 Dec;27(12):1589-91.
Haass C, Steiner H. Alzheimer disease gamma-secretase: a complex story of GxGD-type presenilin proteases. Trends Cell Biol. 2002 Dec;12(12):556-62.
Rojas-Fernandez CH, Chen M, Fernandez HL. Implications of amyloid precursor protein and subsequent beta-amyloid production to the pharmacotherapy of Alzheimer's disease. Pharmacotherapy. 2002 Dec;22(12):1547-63.
Abe H, Kawasaki K, Nakanishi H. pH-Dependent Aggregate Forms and Conformation of Alzheimer Amyloid beta-Peptide (12-24). J Biochem (Tokyo). 2002 Dec;132(6):863-74.
Akita Y. Protein Kinase C-epsilon (PKC-epsilon): Its Unique Structure and Function. J Biochem (Tokyo). 2002 Dec;132(6):847-52.
Schmidt K, Kins S, Schild A, Nitsch RM, Hemmings BA, Götz J. Diversity, developmental regulation and distribution of murine PR55/B subunits of protein phosphatase 2A. Eur J Neurosci. 2002 Dec;16(11):2039-48.
Wilson CJ, Finch CE, Cohen HJ. Cytokines and cognition--the case for a head-to-toe inflammatory paradigm. J Am Geriatr Soc. 2002 Dec;50(12):2041-56.
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