Alzheimer’s Research Papers Dec 2001

Alzheimer’s Research Papers

           

Masliah E, Alford M, Galasko D, Salmon D, Hansen LA, Good PF, Perl DP, Thal L. Cholinergic deficits in the brains of patients with parkinsonism-dementia complex of Guam. Neuroreport. 2001 Dec 21;12(18):3901-3.

Maestú F, Fernández A, Simos PG, Gil-Gregorio P, Amo C, Rodriguez R, Arrazola J, Ortiz T. Spatio-temporal patterns of brain magnetic activity during a memory task in Alzheimer's disease. Neuroreport. 2001 Dec 21;12(18):3917-22.

Stieler JT, Lederer C, Brückner MK, Wolf H, Holzer M, Gertz HJ, Arendt T. Impairment of mitogenic activation of peripheral blood lymphocytes in Alzheimer's disease. Neuroreport. 2001 Dec 21;12(18):3969-72.

Clare PM, Poorman RA, Kelley LC, Watenpaugh KD, Bannow CA, Leach KL. The cyclin-dependent kinases cdk2 and cdk5 act by a random, anticooperative kinetic mechanism. J Biol Chem. 2001 Dec 21;276(51):48292-9.

Choi YT, Jung CH, Lee SR, Bae JH, Baek WK, Suh MH, Park J, Park CW, Suh SI. The green tea polyphenol (-)-epigallocatechin gallate attenuates beta-amyloid-induced neurotoxicity in cultured hippocampal neurons. Life Sci. 2001 Dec 21;70(5):603-14.

Haraguchi T, Ishizu H, Takehisa Y, Kawai K, Yokota O, Terada S, Tsuchiya K, Ikeda K, Morita K, Horike T, Kira S, Kuroda S. Lead content of brain tissue in diffuse neurofibrillary tangles with calcification (DNTC): the possibility of lead neurotoxicity. Neuroreport. 2001 Dec 21;12(18):3887-90.

Merlos-Suárez A, Ruiz-Paz S, Baselga J, Arribas J. Metalloprotease-dependent protransforming growth factor-alpha ectodomain shedding in the absence of tumor necrosis factor-alpha-converting enzyme. J Biol Chem. 2001 Dec 21;276(51):48510-7.

von Bergen M, Barghorn S, Li L, Marx A, Biernat J, Mandelkow EM, Mandelkow E. Mutations of tau protein in frontotemporal dementia promote aggregation of paired helical filaments by enhancing local beta-structure. J Biol Chem. 2001 Dec 21;276(51):48165-74.

 

Hu J, Igarashi A, Kamata M, Nakagawa H. Angiotensin-converting enzyme degrades Alzheimer amyloid beta-peptide (A beta ); retards A beta aggregation, deposition, fibril formation; and inhibits cytotoxicity. J Biol Chem. 2001 Dec 21;276(51):47863-8.

 

Atamna H, Liu J, Ames BN. Heme deficiency selectively interrupts assembly of mitochondrial complex IV in human fibroblasts: revelance to aging. J Biol Chem. 2001 Dec 21;276(51):48410-6.

Nakamura Y, Yamamoto M, Kumamaru E. Significance of the variant and full-length forms of the very low density lipoprotein receptor in brain. Brain Res. 2001 Dec 20;922(2):209-15.

Rajeswaran WG, Cao Y, Huang XP, Wroblewski ME, Colclough T, Lee S, Liu F, Nagy PI, Ellis J, Levine BA, Nocka KH, Messer WS. Design, synthesis, and biological characterization of bivalent 1-methyl-1,2,5,6-tetrahydropyridyl-1,2,5-thiadiazole derivatives as selective muscarinic agonists. J Med Chem. 2001 Dec 20;44(26):4563-76.

Creighton CJ, Reynolds CH, Lee DH, Leo GC, Reitz AB. Conformational analysis of the eight-membered ring of the oxidized cysteinyl-cysteine unit implicated in nicotinic acetylcholine receptor ligand recognition. J Am Chem Soc. 2001 Dec 19;123(50):12664-9.

Gao Y, Pimplikar SW. The gamma -secretase-cleaved C-terminal fragment of amyloid precursor protein mediates signaling to the nucleus. Proc Natl Acad Sci U S A. 2001 Dec 18;98(26):14979-84.

Jellinger KA, Paulus W, Wrocklage C, Litvan I. Traumatic brain injury as a risk factor for Alzheimer disease. Comparison of two retrospective autopsy cohorts with evaluation of ApoE genotype. BMC Neurol. 2001 Dec 18;1:3.

McPhie DL, Golde T, Eckman CB, Yager D, Brant JB, Neve RL. beta-Secretase cleavage of the amyloid precursor protein mediates neuronal apoptosis caused by familial Alzheimer's disease mutations. Brain Res Mol Brain Res. 2001 Dec 16;97(1):103-13.

van Den Hurk WH, Bloemen M, Martens GJ. Expression of the gene encoding the beta-amyloid precursor protein APP in Xenopus laevis. Brain Res Mol Brain Res. 2001 Dec 16;97(1):13-20.

Shiozaki K, Iseki E, Hino H, Kosaka K. Distribution of m1 muscarinic acetylcholine receptors in the hippocampus of patients with Alzheimer's disease and dementia with Lewy bodies-an immunohistochemical study. J Neurol Sci. 2001 Dec 15;193(1):23-8.

McLaughlin DP, Sharma A, McGinley A, Samra GS. The advantages of haplotype analysis of the promoter region of the human apolipoprotein E gene. Anal Biochem. 2001 Dec 15;299(2):183-7.

Thibault O, Hadley R, Landfield PW. Elevated postsynaptic [Ca2+]i and L-type calcium channel activity in aged hippocampal neurons: relationship to impaired synaptic plasticity. J Neurosci. 2001 Dec 15;21(24):9744-56.

Agdeppa ED, Kepe V, Liu J, Flores-Torres S, Satyamurthy N, Petric A, Cole GM, Small GW, Huang SC, Barrio JR. Binding characteristics of radiofluorinated 6-dialkylamino-2-naphthylethylidene derivatives as positron emission tomography imaging probes for beta-amyloid plaques in Alzheimer's disease. J Neurosci. 2001 Dec 15;21(24):RC189.

Vijayan S, El-Akkad E, Grundke-Iqbal I, Iqbal K. A pool of beta-tubulin is hyperphosphorylated at serine residues in Alzheimer disease brain. FEBS Lett. 2001 Dec 14;509(3):375-81.

Wettstein A. [To differentiate Alzheimer's and vascular dementia? Today no longer up to date] MMW Fortschr Med. 2001 Dec 13;143(51-52):41-2.

Gasser US, Gasser T. [Alzheimer dementia. Comparison of the effectiveness of cholinesterase inhibitors and gingko] MMW Fortschr Med. 2001 Dec 13;143(51-52):40-1.

Padberg F, Hampel H, Möller HJ. [Alzheimer patients. To treat with anti-dementia drugs in spite of unanswered questions] MMW Fortschr Med. 2001 Dec 13;143(51-52):43-5.

Martínez M, Hernández AI, Hernanz A. Increased cAMP immunostaining in cerebral vessels in Alzheimer's disease. Brain Res. 2001 Dec 13;922(1):148-52.

Zhang SX, Guo Y, Boulianne GL. Identification of a novel family of putative methyltransferases that interact with human and Drosophila presenilins. Gene. 2001 Dec 12;280(1-2):135-44.

Westlind-Danielsson A, Arnerup G. Spontaneous in vitro formation of supramolecular beta-amyloid structures, "betaamy balls", by beta-amyloid 1-40 peptide. Biochemistry. 2001 Dec 11;40(49):14736-43.

Poeggeler B, Miravalle L, Zagorski MG, Wisniewski T, Chyan YJ, Zhang Y, Shao H, Bryant-Thomas T, Vidal R, Frangione B, Ghiso J, Pappolla MA. Melatonin reverses the profibrillogenic activity of apolipoprotein E4 on the Alzheimer amyloid Abeta peptide. Biochemistry. 2001 Dec 11;40(49):14995-5001.

 

van Denderen JC, van Wieringen GW, Hillen B, Bleys RL. Zinc sulphate-induced anosmia decreases the nerve fibre density in the anterior cerebral artery of the rat. Auton Neurosci. 2001 Dec 10;94(1-2):102-8.

Pedersen NL, Posner SF, Gatz M. Multiple-threshold models for genetic influences on age of onset for Alzheimer disease: findings in Swedish twins. Am J Med Genet. 2001 Dec 8;105(8):724-8.

Taylor A, Ezquerra M, Bagri G, Yip A, Goumidi L, Cottel D, Easton D, Evans JG, Xuereb J, Cairns NJ, Amouyel P, Chartier-Harlin MC, Brayne C, Rubinsztein DC. Alzheimer disease is not associated with polymorphisms in the angiotensinogen and renin genes. Am J Med Genet. 2001 Dec 8;105(8):761-4. ,

Mookherjee P, Johnson GV. Tau phosphorylation during apoptosis of human SH-SY5Y neuroblastoma cells. Brain Res. 2001 Dec 7;921(1-2):31-43.

Fergani A, Yu G, St George-Hyslop P, Checler F. Wild-type and mutated nicastrins do not display aminopeptidase M- and B-like activities. Biochem Biophys Res Commun. 2001 Dec 7;289(3):678-80.

 

Bulteau AL, Verbeke P, Petropoulos I, Chaffotte AF, Friguet B. Proteasome inhibition in glyoxal-treated fibroblasts and resistance of glycated glucose-6-phosphate dehydrogenase to 20 S proteasome degradation in vitro. J Biol Chem. 2001 Dec 7;276(49):45662-8.

 

Giles GI, Tasker KM, Johnson RJ, Jacob C, Peers C, Green KN. Electrochemistry of chalcogen compounds: prediction of antioxidant activity. Chem Commun (Camb). 2001 Dec 7;(23):2490-1.

  

Kamal A, Almenar-Queralt A, LeBlanc JF, Roberts EA, Goldstein LS. Kinesin-mediated axonal transport of a membrane compartment containing beta-secretase and presenilin-1 requires APP. Nature. 2001 Dec 6;414(6864):643-8.

    

Ren H, Ji Q, Liu Y, Ru B. Different protective roles in vitro of alpha- and beta-domains of growth inhibitory factor (GIF) on neuron injuries caused by oxygen free radicals. Biochim Biophys Acta. 2001 Dec 5;1568(2):129-34.

Sánchez-Guerra M, Combarros O, Infante J, Llorca J, Berciano J, Fontalba A, Fernández-Luna JL, Peña N, Fernández-Viadero C. Case-control study and meta-analysis of low density lipoprotein receptor-related protein gene exon 3 polymorphism in Alzheimer's disease. Neurosci Lett. 2001 Dec 4;316(1):17-20. ,

Yamamoto A, Behl C. Human Nck-associated protein 1 and its binding protein affect the metabolism of beta-amyloid precursor protein with Swedish mutation. Neurosci Lett. 2001 Dec 4;316(1):50-4.

Koistinaho M, Ort M, Cimadevilla JM, Vondrous R, Cordell B, Koistinaho J, Bures J, Higgins LS. Specific spatial learning deficits become severe with age in beta -amyloid precursor protein transgenic mice that harbor diffuse beta -amyloid deposits but do not form plaques. Proc Natl Acad Sci U S A. 2001 Dec 4;98(25):14675-80.

Poduslo SE, Yin X. A new locus on chromosome 19 linked with late-onset Alzheimer's disease. Neuroreport. 2001 Dec 4;12(17):3759-61.

Milton NG. Phosphorylation of amyloid-beta at the serine 26 residue by human cdc2 kinase. Neuroreport. 2001 Dec 4;12(17):3839-44.

Tayebati SK, Amenta F, Amici S, El-Assouad D, Gallai V, Ricci A, Parnetti L. Peripheral blood lymphocytes muscarinic cholinergic receptor subtypes in Alzheimer's disease: a marker of cholinergic dysfunction? J Neuroimmunol. 2001 Dec 3;121(1-2):126-31.

Butterfield DA, Drake J, Pocernich C, Castegna A. Evidence of oxidative damage in Alzheimer's disease brain: central role for amyloid beta-peptide. Trends Mol Med. 2001 Dec 1;7(12):548-54.

Goldsbury C, Aebi U, Frey P. Visualizing the growth of Alzheimer's A beta amyloid-like fibrils. Trends Mol Med. 2001 Dec;7(12):582.

Engelhardt E, Moreira DM, Laks J, Marinho VM, Rozenthal M, Oliveira AC. [Alzheimer's disease and magnetic resonance spectroscopy of the hippocampus] Arq Neuropsiquiatr. 2001 Dec;59(4):865-70.

Hama E, Shirotani K, Masumoto H, Sekine-Aizawa Y, Aizawa H, Saido TC. Clearance of extracellular and cell-associated amyloid beta peptide through viral expression of neprilysin in primary neurons. J Biochem. 2001 Dec;130(6):721-6.

Moghadasian MH, McManus BM, Nguyen LB, Shefer S, Nadji M, Godin DV, Green TJ, Hill J, Yang Y, Scudamore CH, Frohlich JJ. Pathophysiology of apolipoprotein E deficiency in mice: relevance to apo E-related disorders in humans. FASEB J. 2001 Dec;15(14):2623-30.

Hashimoto Y, Niikura T, Ito Y, Sudo H, Hata M, Arakawa E, Abe Y, Kita Y, Nishimoto I. Detailed characterization of neuroprotection by a rescue factor humanin against various Alzheimer's disease-relevant insults. J Neurosci. 2001 Dec 1;21(23):9235-45.

Suzuki Y, Critchley HD, Suckling J, Fukuda R, Williams SC, Andrew C, Howard R, Ouldred E, Bryant C, Swift CG, Jackson SH. Functional magnetic resonance imaging of odor identification: the effect of aging. J Gerontol A Biol Sci Med Sci. 2001 Dec;56(12):M756-60.

Holmes C, Smith H, Ganderton R, Arranz M, Collier D, Powell J, Lovestone S. Psychosis and aggression in Alzheimer's disease: the effect of dopamine receptor gene variation. J Neurol Neurosurg Psychiatry. 2001 Dec;71(6):777-9.

Jonker C, Gerritsen DL, van der Steen JT, Bosboom PR, van Campen C, Kleemans AH, Schrijver TL. [Quality of life and dementia. I. Model of assessment of wellbeing in dementia patients] Tijdschr Gerontol Geriatr. 2001 Dec;32(6):252-8.

Hake AM, Farlow MR. New concepts in the drug therapy of Alzheimer's disease. Expert Opin Pharmacother. 2001 Dec;2(12):1975-83.

Gasic-Milenkovic J, Loske C, Deuther-Conrad W, Münch G. Protein "AGEing"--cytotoxicity of a glycated protein increases with its degree of AGE-modification. Z Gerontol Geriatr. 2001 Dec;34(6):457-60.

Sánchez A, Guzmán A, Ortiz A, Rembao D, Espinosa B, Zenteno E, Guevara J. Toluidine blue-O staining of prion protein deposits. Histochem Cell Biol. 2001 Dec;116(6):519-24.

Akiyama K, Tanaka R, Sato M, Takeda N. Cognitive dysfunction and histological findings in adult rats one year after whole brain irradiation. Neurol Med Chir (Tokyo). 2001 Dec;41(12):590-8.

Murman DL. The costs of caring: medical costs of Alzheimer's disease and the managed care environment. J Geriatr Psychiatry Neurol. 2001 Winter;14(4):168-78.

Milton NG. Inhibition of catalase activity with 3-amino-triazole enhances the cytotoxicity of the Alzheimer's amyloid-beta peptide. Neurotoxicology. 2001 Dec;22(6):767-74.

Kruzel M L, Janusz M, Lisowski J, Fischleigh R V, Georgiades J A. Towards an understanding of biological role of colostrinin peptides. J Mol Neurosci. 2001 Dec;17(3):379-89.

 

Autret A, Lucas B, Mondon K, Hommet C, Corcia P, Saudeau D, de Toffol B. Sleep and brain lesions: a critical review of the literature and additional new cases. Neurophysiol Clin. 2001 Dec 1;31(6):356-75.

Kudo T, Takeda M. [Alzheimer disease] Nippon Rinsho. 2001 Dec;59 Suppl 8:504-10.

Okamura N, Arai H, Maruyama M, Matsui T, Tanji H, Sasaki H, Yoshida H, Sugita M. Serum cholesterol and cerebrospinal fluid amyloid beta protein in Alzheimer's disease. J Am Geriatr Soc. 2001 Dec;49(12):1738-9.

Ko LW, Sheu KF, Thaler H T, Markesbery W R, Blass J P. Selective loss of KGDHC-enriched neurons in Alzheimer temporal cortex: does mitochondrial variation contribute to selective vulnerability? J Mol Neurosci. 2001 Dec;17(3):361-9.

Miller MM, Monjan AA, Buckholtz NS. Estrogen replacement therapy for the potential treatment or prevention of Alzheimer's disease. Ann N Y Acad Sci. 2001 Dec;949:223-34.

Jang J, Sin KS, Park H. Synthesis of (+/-)-methyl-(1-aryl-4-pyridin-3-yl-but-3-enyl)-amines. Arch Pharm Res. 2001 Dec;24(6):503-7.

Methia N, Andre P, Hafezi-Moghadam A, Economopoulos M, Thomas KL, Wagner DD. ApoE Deficiency Compromises the Blood Brain Barrier Especially after Injury. Mol Med. 2001 Dec;7(12):810-5.

Musa A, Lehrach H, Russo VA. Distinct expression patterns of two zebrafish homologues of the human APP gene during embryonic development. Dev Genes Evol. 2001 Dec;211(11):563-7.

Maruyama M, Arai H, Sugita M, Tanji H, Higuchi M, Okamura N, Matsui T, Higuchi S, Matsushita S, Yoshida H, Sasaki H. Cerebrospinal fluid amyloid beta(1-42) levels in the mild cognitive impairment stage of Alzheimer's disease. Exp Neurol. 2001 Dec;172(2):433-6. ,

 

Frederiks JA. Alzheimer's Disease and Related Disorders Annual 2001, Edited by S. Gauthier and J.L. Cummings, Martin Dunitz, London, 2001, 216 pp., ISBN 1-84184-022-X. Clin Neurol Neurosurg. 2001 Dec;103(4):265.

Itzhaki RF, Dobson CB, Lin WR, Wozniak MA. Association of HSV1 and apolipoprotein E-varepsilon4 in Alzheimer's disease. J Neurovirol. 2001 Dec 1;7(6):570-1.

Love R. Memory loss independent of plaque formation in Alzheimer's model. Lancet. 2001 Dec 1;358(9296):1879.

Colpaert FC, Koek W, Bruins Slot LA. Evidence that mnesic states govern normal and disordered memory. Behav Pharmacol. 2001 Dec;12(8):575-89.

Ely JT. Mercury induced Alzheimer's disease: accelerating incidence? Bull Environ Contam Toxicol. 2001 Dec;67(6):800-6.

Möller H J, Hartmann A, Kessler C, Rainer M, Brown T, Gamand S, Lehert P. Naftidrofuryl in the treatment of vascular dementia. Eur Arch Psychiatry Clin Neurosci. 2001 Dec;251(6):247-54.

Tabner B J, Turnbull S, El-Agnaf O, Allsop D. Production of reactive oxygen species from aggregating proteins implicated in Alzheimer's disease, Parkinson's disease and other neurodegenerative diseases. Curr Top Med Chem. 2001 Dec;1(6):507-17.

Adams J D, Klaidman L K, Chang M L, Yang J. Brain oxidative stress--analytical chemistry and thermodynamics of glutathione and NADPH. Curr Top Med Chem. 2001 Dec;1(6):473-82.

Alexandrov A V. Citicoline. Ferrer Internacional. Curr Opin Investig Drugs. 2001 Dec;2(12):1757-62.

Carter J, Lippa CF. Beta-amyloid, neuronal death and Alzheimer's disease. Curr Mol Med. 2001 Dec;1(6):733-7.

Tórsdóttir G, Kristinsson J, Hreidarsson S, Snaedal J, Jóhannesson T. Copper, ceruloplasmin and superoxide dismutase (SOD1) in patients with Down's syndrome. Pharmacol Toxicol. 2001 Dec;89(6):320-5.

Gordon RK, Nigam SV, Weitz JA, Dave JR, Doctor BP, Ved HS. The NMDA receptor ion channel: a site for binding of Huperzine A. J Appl Toxicol. 2001 Dec 1;21 Suppl 1:S47-51.

Nathan P J, Stough C. Inspection time: a neuropsychophysiological test for measuring the functional integrity of the cholinergic system. Med Hypotheses. 2001 Dec;57(6):759-60.

Sugaya K, Brannen C L. Stem cell strategies for neuroreplacement therapy in Alzheimer's disease. Med Hypotheses. 2001 Dec;57(6):697-700.

Allain H, Tribut O, Reymann JM, Polard E, Lecavorzin P, Bentue-Ferrer D. [Perspectives for drug treatment in Alzheimer's disease] Ann Med Interne (Paris). 2001 Dec;152(8):527-32.

Natté R, Maat-Schieman ML, Haan J, Bornebroek M, Roos RA, van Duinen SG. Dementia in hereditary cerebral hemorrhage with amyloidosis-Dutch type is associated with cerebral amyloid angiopathy but is independent of plaques and neurofibrillary tangles. Ann Neurol. 2001 Dec;50(6):765-72.

Sodeyama N, Mizusawa H, Yamada M, Itoh Y, Otomo E, Matsushita M. Lack of association of neprilysin polymorphism with Alzheimer's disease and Alzheimer's disease-type neuropathological changes. J Neurol Neurosurg Psychiatry. 2001 Dec;71(6):817-8. , ,

Takao M, Ghetti B, Murrell JR, Unverzagt FW, Giaccone G, Tagliavini F, Bugiani O, Piccardo P, Hulette CM, Crain BJ, Farlow MR, Heyman A. Ectopic white matter neurons, a developmental abnormality that may be caused by the PSEN1 S169L mutation in a case of familial AD with myoclonus and seizures. J Neuropathol Exp Neurol. 2001 Dec;60(12):1137-52.

Atzori C, Ghetti B, Piva R, Srinivasan AN, Zolo P, Delisle MB, Mirra SS, Migheli A. Activation of the JNK/p38 pathway occurs in diseases characterized by tau protein pathology and is related to tau phosphorylation but not to apoptosis. J Neuropathol Exp Neurol. 2001 Dec;60(12):1190-7.

Husseman JW, Hallows JL, Bregman DB, Leverenz JB, Nochlin D, Jin LW, Vincent I. Hyperphosphorylation of RNA polymerase II and reduced neuronal RNA levels precede neurofibrillary tangles in Alzheimer disease. J Neuropathol Exp Neurol. 2001 Dec 1;60(12):1219-32.

Kemper S, Marquis J, Thompson M. Longitudinal change in language production: effects of aging and dementia on grammatical complexity and propositional content. Psychol Aging. 2001 Dec;16(4):600-14.

Yamazaki M, Sakura N, Chiba K, Mohri T. Prevention of the neurotoxicity of the amyloid beta protein by genipin. Biol Pharm Bull. 2001 Dec;24(12):1454-5.

Hyde LA, Crnic LS. Age-related deficits in context discrimination learning in Ts65Dn mice that model Down syndrome and Alzheimer's disease. Behav Neurosci. 2001 Dec 1;115(6):1239-46.

Gu HF. [Single nucleotide polymorphisms(SNPs)and SNP databases] Zhonghua Yi Xue Yi Chuan Xue Za Zhi. 2001 Dec;18(6):479-81.

Dutta K, Alexandrov A, Huang H, Pascal SM. pH-induced folding of an apoptotic coiled coil. Protein Sci. 2001 Dec;10(12):2531-40.

Tacnet-Delorme P, Chevallier S, Arlaud GJ. Beta-amyloid fibrils activate the C1 complex of complement under physiological conditions: evidence for a binding site for A beta on the C1q globular regions. J Immunol. 2001 Dec 1;167(11):6374-81.

Niwa K, Porter VA, Kazama K, Cornfield D, Carlson GA, Iadecola C. A beta-peptides enhance vasoconstriction in cerebral circulation. Am J Physiol Heart Circ Physiol. 2001 Dec;281(6):H2417-24.

Dermaut B, Kumar-Singh S, de Jonghe C, Cruts M, Löfgren A, Lübke U, Cras P, Dom R, De Deyn PP, Martin JJ, van Broeckhoven C. Cerebral amyloid angiopathy is a pathogenic lesion in Alzheimer's disease due to a novel presenilin 1 mutation. Brain. 2001 Dec;124(Pt 12):2383-92.

Blass JP. Brain metabolism and brain disease: is metabolic deficiency the proximate cause of Alzheimer dementia? J Neurosci Res. 2001 Dec 1;66(5):851-6.

Robinson SR. Changes in the cellular distribution of glutamine synthetase in Alzheimer's disease. J Neurosci Res. 2001 Dec 1;66(5):972-80.

Lee MK, Park AJ, Nam BY, Min KJ, Kee BS, Park DB. Apolipoprotein E genotype in Korean schizophrenic patients. J Korean Med Sci. 2001 Dec;16(6):781-3.

Lovestone S, Murray D. Acetylcholinesterase treatment--modelling potential demand and auditing practice. Int J Geriatr Psychiatry. 2001 Dec;16(12):1136-42.

Chan WC, Lam LC, Choy CN, Leung VP, Li SW, Chiu HF. A double-blind randomised comparison of risperidone and haloperidol in the treatment of behavioural and psychological symptoms in Chinese dementia patients. Int J Geriatr Psychiatry. 2001 Dec;16(12):1156-62.

Shimokawa A, Yatomi N, Anamizu S, Torii S, Isono H, Sugai Y, Kohno M. Influence of deteriorating ability of emotional comprehension on interpersonal behavior in Alzheimer-type dementia. Brain Cogn. 2001 Dec;47(3):423-33.

Smith EE, Rhee J, Dennis K, Grossman M. Inductive reasoning in Alzheimer's disease. Brain Cogn. 2001 Dec;47(3):494-503.

Shigeta M, Homma A. Donepezil for Alzheimer's disease: pharmacodynamic, pharmacokinetic, and clinical profiles. CNS Drug Rev. 2001 Winter;7(4):353-68.

Olde Rikkert MG, Rigaud AS. Melatonin in elderly patients with insomnia. A systematic review. Z Gerontol Geriatr. 2001 Dec;34(6):491-7.

Landes AM, Sperry SD, Strauss ME, Geldmacher DS. Apathy in Alzheimer's disease. J Am Geriatr Soc. 2001 Dec;49(12):1700-7.

Kobayashi H, Shin-Ya K, Nagai K, Suzuki K, Hayakawa Y, Seto H, Yun B S, Ryoo I J, Kim J S, Kim C J, Yoo I D. Neuroprotectins A and B, bicyclohexapeptides protecting chick telencephalic neuronal cells from excitotoxicity. I. Fermentation, isolation, physico-chemical properties and biological activity. J Antibiot (Tokyo). 2001 Dec;54(12):1013-8.

Anthony M, Williams JK, Dunn BK. What would be the properties of an ideal SERM? Ann N Y Acad Sci. 2001 Dec;949:261-78.

Balin BJ, Appelt DM. Role of infection in Alzheimer's disease. J Am Osteopath Assoc. 2001 Dec;101(12 Suppl Pt 1):S1-6.

 

Counts SE, Perez SE, Kahl U, Bartfai T, Bowser RP, Deecher DC, Mash DC, Crawley JN, Mufson EJ. Galanin: neurobiologic mechanisms and therapeutic potential for Alzheimer's disease. CNS Drug Rev. 2001 Winter;7(4):445-70.

Patel RN. Biocatalytic synthesis of intermediates for the synthesis of chiral drug substances. Curr Opin Biotechnol. 2001 Dec;12(6):587-604.

Toro V C, Tehranian R, Zetterström M, Eriksson G, Langel U, Bartfai T, Iverfeld K. Increased gene expression of interleukin-1alpha and interleukin-6 in rat primary glial cells induced by beta-amyloid fragment. J Mol Neurosci. 2001 Dec;17(3):341-50.

Min SK, Moon IW, Ko RW, Shin HS. Effects of transdermal nicotine on attention and memory in healthy elderly non-smokers. Psychopharmacology (Berl). 2001 Dec;159(1):83-8.

Graf RA. Detouring destruction: a role for inhibitory neuronal activity in preventing neuronal loss--implications for Alzheimer's disease. J Am Osteopath Assoc. 2001 Dec;101(12 Suppl Pt 1):S7-10.

Tales A, Troscianko T, Lush D, Haworth J, Wilcock GK, Butler SR. The pupillary light reflex in aging and Alzheimer's disease. Aging (Milano). 2001 Dec;13(6):473-8.

Tuppo EE, Forman LJ. Free radical oxidative damage and Alzheimer's disease. J Am Osteopath Assoc. 2001 Dec;101(12 Suppl Pt 1):S11-5.

Ghiso J, Révész T, Holton J, Rostagno A, Lashley T, Houlden H, Gibb G, Anderton B, Bek T, Bojsen-Møller M, Wood N, Vidal R, Braendgaard H, Plant G, Frangione B. Chromosome 13 dementia syndromes as models of neurodegeneration. Amyloid. 2001 Dec;8(4):277-84.

Braida D, Sala M. Eptastigmine: ten years of pharmacology, toxicology, pharmacokinetic, and clinical studies. CNS Drug Rev. 2001 Winter;7(4):369-86.

Arlt S, Kontush A, Müller-Thomsen T, Beisiegel U. [Lipid peroxidation as a common pathomechanism in coronary heart disease and Alzheimer disease] Z Gerontol Geriatr. 2001 Dec;34(6):461-5.

Fernandes M L, Saad M J, Velloso L A. Effects of age on elements of insulin-signaling pathway in central nervous system of rats. Endocrine. 2001 Dec;16(3):227-34.

Chung HM, Struhl G. Nicastrin is required for Presenilin-mediated transmembrane cleavage in Drosophila. Nat Cell Biol. 2001 Dec;3(12):1129-32.

Parvathy S, Davies P, Haroutunian V, Purohit DP, Davis KL, Mohs RC, Park H, Moran TM, Chan JY, Buxbaum JD. Correlation between Abetax-40-, Abetax-42-, and Abetax-43-containing amyloid plaques and cognitive decline. Arch Neurol. 2001 Dec;58(12):2025-32.

Qiu C, Bäckman L, Winblad B, Agüero-Torres H, Fratiglioni L. The influence of education on clinically diagnosed dementia incidence and mortality data from the Kungsholmen Project. Arch Neurol. 2001 Dec;58(12):2034-9.

    

Compton J, van Amelsvoort T, Murphy D. HRT and its effect on normal ageing of the brain and dementia. Br J Clin Pharmacol. 2001 Dec;52(6):647-53.

Shimada M, Meguro K, Inagaki H, Ishizaki J, Yamadori A. Global intellectual deterioration in Alzheimer's disease and a reverse model of intellectual development: an applicability of the Binet scale. Psychiatry Clin Neurosci. 2001 Dec;55(6):559-63.

Meguro K, Shimada M, Yamaguchi S, Ishizaki J, Ishii H, Shimada Y, Sato M, Yamadori A, Sekita Y. Cognitive function and frontal lobe atrophy in normal elderly adults: Implications for dementia not as aging-related disorders and the reserve hypothesis. Psychiatry Clin Neurosci. 2001 Dec;55(6):565-72.

Miwa C, Ueki A, Shinjo H, Simode H, Morita Y. Long-term synaptic alteration in the rat hippocampal CA3 field following an entorhinal cortex lesion. Psychiatry Clin Neurosci. 2001 Dec;55(6):573-8.

Daugherty BL, Green SA. Endosomal sorting of amyloid precursor protein-P-selectin chimeras influences secretase processing. Traffic. 2001 Dec;2(12):908-16.

Banfield MJ, Naylor RL, Robertson AG, Allen SJ, Dawbarn D, Brady RL. Specificity in Trk receptor:neurotrophin interactions: the crystal structure of TrkB-d5 in complex with neurotrophin-4/5. Structure (Camb). 2001 Dec;9(12):1191-9.

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