Alzheimer’s Research Papers April 2001

Alzheimer’s Research Papers     

           

Lachowicz JE, Duffy RA, Ruperto V, Kozlowski J, Zhou G, Clader J, Billard W, Binch H, Crosby G, Cohen-Williams M, Strader CD, Coffin V. Facilitation of acetylcholine release and improvement in cognition by a selective M2 muscarinic antagonist, SCH 72788. Life Sci. 2001 Apr 27;68(22-23):2585-92.

Zhang L, Song L, Terracina G, Liu Y, Pramanik B, Parker E. Biochemical characterization of the gamma-secretase activity that produces beta-amyloid peptides. Biochemistry. 2001 Apr 24;40(16):5049-55.

Sobel RK. A tonic for dementia? Genes for Alzheimer's. US News World Rep. 2001 Apr 23;130(16):54.

Gorman C. Brain games. Alzheimer's gene therapy. Time. 2001 Apr 23;157(16):64.

Kuo YM, Kokjohn TA, Beach TG, Sue LI, Brune D, Lopez JC, Kalback WM, Abramowski D, Sturchler-Pierrat C, Staufenbiel M, Roher AE. Comparative analysis of amyloid-beta chemical structure and amyloid plaque morphology of transgenic mouse and Alzheimer's disease brains. J Biol Chem. 2001 Apr 20;276(16):12991-8.

Kallberg Y, Gustafsson M, Persson B, Thyberg J, Johansson J. Prediction of amyloid fibril-forming proteins. J Biol Chem. 2001 Apr 20;276(16):12945-50.

Aksenov MY, Markesbery WR. Changes in thiol content and expression of glutathione redox system genes in the hippocampus and cerebellum in Alzheimer's disease. Neurosci Lett. 2001 Apr 20;302(2-3):141-5.

Hartlage-Rübsamen M, Apelt J, Schliebs R. Fibrillary beta-amyloid deposits are closely associated with atrophic nitric oxide synthase (NOS)-expressing neurons but do not upregulate the inducible NOS in transgenic Tg2576 mouse brain with Alzheimer pathology. Neurosci Lett. 2001 Apr 20;302(2-3):73-6.

Ki CS, Na DL, Kim HJ, Kim JW. Alpha-1 antichymotrypsin and alpha-2 macroglobulin gene polymorphisms are not associated with Korean late-onset Alzheimer's disease. Neurosci Lett. 2001 Apr 20;302(2-3):69-72. ,

Su JH, Zhao M, Anderson AJ, Srinivasan A, Cotman CW. Activated caspase-3 expression in Alzheimer's and aged control brain: correlation with Alzheimer pathology. Brain Res. 2001 Apr 20;898(2):350-7.

Ingelson M, Fabre SF, Lilius L, Andersen C, Viitanen M, Almkvist O, Wahlund LO, Lannfelt L. Increased risk for frontotemporal dementia through interaction between tau polymorphisms and apolipoprotein E epsilon4. Neuroreport. 2001 Apr 17;12(5):905-9.

Eckert GP, Kirsch C, Mueller WE. Differential effects of lovastatin treatment on brain cholesterol levels in normal and apoE-deficient mice. Neuroreport. 2001 Apr 17;12(5):883-7.

Bleys RL, Cowen T. Innervation of cerebral blood vessels: morphology, plasticity, age-related, and Alzheimer's disease-related neurodegeneration. Microsc Res Tech. 2001 Apr 15;53(2):106-18.

  

Yang Y, Geldmacher DS, Herrup K. DNA replication precedes neuronal cell death in Alzheimer's disease. J Neurosci. 2001 Apr 15;21(8):2661-8.

 

Gasparini L, Gouras GK, Wang R, Gross RS, Beal MF, Greengard P, Xu H. Stimulation of beta-amyloid precursor protein trafficking by insulin reduces intraneuronal beta-amyloid and requires mitogen-activated protein kinase signaling. J Neurosci. 2001 Apr 15;21(8):2561-70.

 

Perry KW, Nisenbaum LK, George CA, Shannon HE, Felder CC, Bymaster FP. The muscarinic agonist xanomeline increases monoamine release and immediate early gene expression in the rat prefrontal cortex. Biol Psychiatry. 2001 Apr 15;49(8):716-25.

Eckert A, Steiner B, Marques C, Leutz S, Romig H, Haass C, Müller WE. Elevated vulnerability to oxidative stress-induced cell death and activation of caspase-3 by the Swedish amyloid precursor protein mutation. J Neurosci Res. 2001 Apr 15;64(2):183-92.

Thompson CA. FDA approves galantamine for Alzheimer's disease. Am J Health Syst Pharm. 2001 Apr 15;58(8):649.

van Den Hurk WH, Willems HJ, Bloemen M, Martens GJ. Novel frameshift mutations near short simple repeats. J Biol Chem. 2001 Apr 13;276(15):11496-8.

Kim H, Bang OY, Jung MW, Ha SD, Hong HS, Huh K, Kim SU, Mook-Jung I. Neuroprotective effects of estrogen against beta-amyloid toxicity are mediated by estrogen receptors in cultured neuronal cells. Neurosci Lett. 2001 Apr 13;302(1):58-62.

 

Schneider I, Reverse D, Dewachter I, Ris L, Caluwaerts N, Kuiperi C, Gilis M, Geerts H, Kretzschmar H, Godaux E, Moechars D, Van Leuven F, Herms J. Mutant presenilins disturb neuronal calcium homeostasis in the brain of transgenic mice, decreasing the threshold for excitotoxicity and facilitating long-term potentiation. J Biol Chem. 2001 Apr 13;276(15):11539-44.

Bodendorf U, Fischer F, Bodian D, Multhaup G, Paganetti P. A splice variant of beta-secretase deficient in the amyloidogenic processing of the amyloid precursor protein. J Biol Chem. 2001 Apr 13;276(15):12019-23.

Wolfson C, Wolfson DB, Asgharian M, M'Lan CE, Ostbye T, Rockwood K, Hogan DB, Clinical Progression of Dementia Study Group. A reevaluation of the duration of survival after the onset of dementia. N Engl J Med. 2001 Apr 12;344(15):1111-6.

Lecerf JM, Shirley TL, Zhu Q, Kazantsev A, Amersdorfer P, Housman DE, Messer A, Huston JS. Human single-chain Fv intrabodies counteract in situ huntingtin aggregation in cellular models of Huntington's disease. Proc Natl Acad Sci U S A. 2001 Apr 10;98(8):4764-9.

Liu Q, Kawai H, Berg DK. beta -Amyloid peptide blocks the response of alpha 7-containing nicotinic receptors on hippocampal neurons. Proc Natl Acad Sci U S A. 2001 Apr 10;98(8):4734-9.

Jagust W, Thisted R, Devous MD, Van Heertum R, Mayberg H, Jobst K, Smith AD, Borys N. SPECT perfusion imaging in the diagnosis of Alzheimer's disease: a clinical-pathologic study. Neurology. 2001 Apr 10;56(7):950-6.

Sagara Y, Everall IP, Mallory M, Everson A, Langford D, Masliah E. Fibroblast growth factor 1 regulates signaling via the GSK3{beta} pathway: implications for neuroprotection. J Biol Chem. 2001 Apr 9;

Benjannet S, Elagoz A, Wickham L, Mamarbachi M, Munzer JS, Basak A, Lazure C, Cromlish JA, Sisodia S, Checler F, Chrétien M, Seidah NG. Post-translational processing of beta-secretase (beta-amyloid-converting enzyme) and its ectodomain shedding. The pro- and transmembrane/cytosolic domains affect its cellular activity and amyloid-beta production. J Biol Chem. 2001 Apr 6;276(14):10879-87.

 

Schupf N, Patel B, Silverman W, Zigman WB, Zhong N, Tycko B, Mehta PD, Mayeux R. Elevated plasma amyloid beta-peptide 1-42 and onset of dementia in adults with Down syndrome. Neurosci Lett. 2001 Apr 6;301(3):199-203.

Smits HA, de Vos NM, Wat JW, van der Bruggen T, Verhoef J, Nottet HS. Intracellular pathways involved in TNF-alpha and superoxide anion release by Abeta(1-42)-stimulated primary human macrophages. J Neuroimmunol. 2001 Apr 2;115(1-2):144-51.

Sramek JJ, Veroff AE, Cutler NR. The status of ongoing trials for mild cognitive impairment. Expert Opin Investig Drugs. 2001 Apr;10(4):741-52.

Jhee S, Shiovitz T, Crawford AW, Cutler NR. Beta-amyloid therapies in Alzheimer's disease. Expert Opin Investig Drugs. 2001 Apr;10(4):593-605.

Szczepanik AM, Rampe D, Ringheim GE. Amyloid-beta peptide fragments p3 and p4 induce pro-inflammatory cytokine and chemokine production in vitro and in vivo. J Neurochem. 2001 Apr;77(1):304-17.

Troy CM, Rabacchi SA, Xu Z, Maroney AC, Connors TJ, Shelanski ML, Greene LA. beta-Amyloid-induced neuronal apoptosis requires c-Jun N-terminal kinase activation. J Neurochem. 2001 Apr;77(1):157-64.

Cheng CM, Cohen M, Wang J, Bondy CA. Estrogen augments glucose transporter and IGF1 expression in primate cerebral cortex. FASEB J. 2001 Apr;15(6):907-15.

King ME, Ghoshal N, Wall JS, Binder LI, Ksiezak-Reding H. Structural analysis of Pick's disease-derived and in vitro-assembled tau filaments. Am J Pathol. 2001 Apr;158(4):1481-90.

 

Matsuoka Y, Picciano M, Malester B, LaFrancois J, Zehr C, Daeschner JM, Olschowka JA, Fonseca MI, O'Banion MK, Tenner AJ, Lemere CA, Duff K. Inflammatory responses to amyloidosis in a transgenic mouse model of Alzheimer's disease. Am J Pathol. 2001 Apr;158(4):1345-54.

 

Grady CL, Furey ML, Pietrini P, Horwitz B, Rapoport SI. Altered brain functional connectivity and impaired short-term memory in Alzheimer's disease. Brain. 2001 Apr;124(Pt 4):739-56.

Gainotti G, Marra C, Villa G. A double dissociation between accuracy and time of execution on attentional tasks in Alzheimer's disease and multi-infarct dementia. Brain. 2001 Apr;124(Pt 4):731-8.

Murre JM, Graham KS, Hodges JR. Semantic dementia: relevance to connectionist models of long-term memory. Brain. 2001 Apr;124(Pt 4):647-75.

Yon JM. Protein folding: a perspective for biology, medicine and biotechnology. Braz J Med Biol Res. 2001 Apr;34(4):419-35.

Kim HC, Kim DK, Choi IJ, Kang KH, Yi SD, Park J, Park YN. Relation of apolipoprotein E polymorphism to clinically diagnosed Alzheimer's disease in the Korean population. Psychiatry Clin Neurosci. 2001 Apr;55(2):115-20.

Furuno T, Kawanishi C, Iseki E, Onishi H, Sugiyama N, Suzuki K, Kosaka K. No evidence of an association between CYP2D6 polymorphisms among Japanese and dementia with Lewy bodies. Psychiatry Clin Neurosci. 2001 Apr;55(2):89-92.

Kergoat H, Kergoat MJ, Justino L, Chertkow H, Robillard A, Bergman H. An evaluation of the retinal nerve fiber layer thickness by scanning laser polarimetry in individuals with dementia of the Alzheimer type. Acta Ophthalmol Scand. 2001 Apr;79(2):187-91.

Malchiodi-Albedi F, Domenici MR, Paradisi S, Bernardo A, Ajmone-Cat MA, Minghetti L. Astrocytes contribute to neuronal impairment in beta A toxicity increasing apoptosis in rat hippocampal neurons. Glia. 2001 Apr 1;34(1):68-72.

Taylor AE, Yip A, Brayne C, Easton D, Evans JG, Xuereb J, Cairns N, Esiri MM, Rubinsztein DC. Genetic association of an LBP-1c/CP2/LSF gene polymorphism with late onset Alzheimer's disease. J Med Genet. 2001 Apr;38(4):232-3. ,

Whalley LJ. Early-onset Alzheimer's disease in Scotland: environmental and familial factors. Br J Psychiatry. 2001 Apr;178(Suppl 40):S53-9.

Ala TA, Hughes LF, Kyrouac GA, Ghobrial MW, Elble RJ. Pentagon copying is more impaired in dementia with Lewy bodies than in Alzheimer's disease. J Neurol Neurosurg Psychiatry. 2001 Apr;70(4):483-8.

Klein WL, Krafft GA, Finch CE. Targeting small Abeta oligomers: the solution to an Alzheimer's disease conundrum? Trends Neurosci. 2001 Apr;24(4):219-24.

Gerlai R. Alzheimer's disease: beta-amyloid hypothesis strengthened! Trends Neurosci. 2001 Apr;24(4):199.

Inagaki C, Hattori N, Kitagawa K, Zeng XT, Yagyu K. Cl(-)-ATPase in rat brain and kidney. J Exp Zool. 2001 Apr 1;289(4):224-31.

Molloy AM, Scott JM. Folates and prevention of disease. Public Health Nutr. 2001 Apr;4(2B):601-9.

Exley C, Korchazhkina OV. Promotion of formation of amyloid fibrils by aluminium adenosine triphosphate (AlATP). J Inorg Biochem. 2001 Apr;84(3-4):215-24.

Belloir B, Kövari E, Surini-Demiri M, Savioz A. Altered apolipoprotein D expression in the brain of patients with Alzheimer disease. J Neurosci Res. 2001 Apr 1;64(1):61-9.

Kantarci K, Jack CR, Xu YC, Campeau NG, O'Brien PC, Smith GE, Ivnik RJ, Boeve BF, Kokmen E, Tangalos EG, Petersen RC. Mild cognitive impairment and Alzheimer disease: regional diffusivity of water. Radiology. 2001 Apr;219(1):101-7.

Schwartz RB. Apparent diffusion coefficient mapping in patients with Alzheimer disease or mild cognitive impairment and in normally aging control subjects: present and future. Radiology. 2001 Apr;219(1):8-9.

Harrison PM, Chan HS, Prusiner SB, Cohen FE. Conformational propagation with prion-like characteristics in a simple model of protein folding. Protein Sci. 2001 Apr;10(4):819-35.

Selkoe DJ. Alzheimer's disease: genes, proteins, and therapy. Physiol Rev. 2001 Apr;81(2):741-66.

 

Dietschy JM, Turley SD. Cholesterol metabolism in the brain. Curr Opin Lipidol. 2001 Apr;12(2):105-12.

 

Yu WH, Fraser PE. S100beta interaction with tau is promoted by zinc and inhibited by hyperphosphorylation in Alzheimer's disease. J Neurosci. 2001 Apr 1;21(7):2240-6.

Montine TJ, Kaye JA, Montine KS, McFarland L, Morrow JD, Quinn JF. Cerebrospinal fluid abeta42, tau, and f2-isoprostane concentrations in patients with Alzheimer disease, other dementias, and in age-matched controls. Arch Pathol Lab Med. 2001 Apr;125(4):510-2. ,

Gyure KA, Durham R, Stewart WF, Smialek JE, Troncoso JC. Intraneuronal abeta-amyloid precedes development of amyloid plaques in Down syndrome. Arch Pathol Lab Med. 2001 Apr;125(4):489-92.

Zhao X, Kuryatov A, Lindstrom JM, Yeh JZ, Narahashi T. Nootropic drug modulation of neuronal nicotinic acetylcholine receptors in rat cortical neurons. Mol Pharmacol. 2001 Apr;59(4):674-83.

Fabre SF, Forsell C, Viitanen M, Sjögren M, Wallin A, Blennow K, Blomberg M, Andersen C, Wahlund LO, Lannfelt L. Clinic-based cases with frontotemporal dementia show increased cerebrospinal fluid tau and high apolipoprotein E epsilon4 frequency, but no tau gene mutations. Exp Neurol. 2001 Apr;168(2):413-8. ,

Vogelsberg-Ragaglia V, Schuck T, Trojanowski JQ, Lee VM. PP2A mRNA expression is quantitatively decreased in Alzheimer's disease hippocampus. Exp Neurol. 2001 Apr;168(2):402-12.

Quinn J, Davis F, Woodward WR, Eckenstein F. Beta-amyloid plaques induce neuritic dystrophy of nitric oxide-producing neurons in a transgenic mouse model of Alzheimer's disease. Exp Neurol. 2001 Apr;168(2):203-12.

Emre M, Qizilbash N. Experimental approaches and drugs in development for the treatment of dementia. Expert Opin Investig Drugs. 2001 Apr;10(4):607-17.

Shiba K, Mori H, Ikeda E, Sumiya H, Tonami N. The potential of radioiodinated (-)-m-iodovesamicol for diagnosing cholinergic deficit dementia. Nucl Med Biol. 2001 Apr;28(3):261-4.

Whalley LJ. Early-onset Alzheimer's disease in Scotland: environmental and familial factors. Br J Psychiatry Suppl. 2001 Apr;40:s53-9.

Ferrer I, Blanco R, Carmona M, Ribera R, Goutan E, Puig B, Rey MJ, Cardozo A, Viñals F, Ribalta T. Phosphorylated map kinase (ERK1, ERK2) expression is associated with early tau deposition in neurones and glial cells, but not with increased nuclear DNA vulnerability and cell death, in Alzheimer disease, Pick's disease, progressive supranuclear palsy and corticobasal degeneration. Brain Pathol. 2001 Apr;11(2):144-58.

Peterson A, Lantz MS, American Association for Geriatric Psychiatry. Is it Alzheimer's? Neuropsychological testing helps to clarify diagnostic puzzle. Geriatrics. 2001 Apr;56(4):58, 61.

Momcilovic B, Alkhatib HA, Duerre JA, Cooley M, Long WM, Harris TR, Lykken GI. Environmental lead-210 and bismuth-210 accrue selectively in the brain proteins in alzheimer disease and brain lipids in parkinson disease. Alzheimer Dis Assoc Disord. 2001 Apr;15(2):106-15.

Aisen PS, Marin DB, Brickman AM, Santoro J, Fusco M. Pilot tolerability studies of hydroxychloroquine and colchicine in alzheimer disease. Alzheimer Dis Assoc Disord. 2001 Apr;15(2):96-101.

Goldman WP, Morris JC. Evidence that age-associated memory impairment is not a normal variant of aging. Alzheimer Dis Assoc Disord. 2001 Apr;15(2):72-9.

Muehlhauser F, Liebl U, Kuehl S, Walter S, Bertsch T, Fassbender K. Aggregation-Dependent interaction of the Alzheimer's beta-amyloid and microglia. Clin Chem Lab Med. 2001 Apr;39(4):313-6.

Hopman-Rock M, Tak EC, Staats PG, Jonker C, Wind AW. [Indicators of early Alzheimer dementia in family practice. Development and validation of the Observation List of Early Symptoms of Dementia (OLD)] Tijdschr Gerontol Geriatr. 2001 Apr;32(2):74-81.

Ishii K, Willoch F, Minoshima S, Drzezga A, Ficaro EP, Cross DJ, Kuhl DE, Schwaiger M. Statistical brain mapping of 18F-FDG PET in Alzheimer's disease: validation of anatomic standardization for atrophied brains. J Nucl Med. 2001 Apr;42(4):548-57.

Grossberg G, Desai A. Review of rivastigmine and its clinical applications in Alzheimer's disease and related disorders. Expert Opin Pharmacother. 2001 Apr;2(4):653-66.

Lawlor BA, McCarron M, Wilson G, McLoughlin M. Temporal lobe-oriented CT scanning and dementia in Down's syndrome. Int J Geriatr Psychiatry. 2001 Apr;16(4):427-9.

Maiese K. The dynamics of cellular injury: transformation into neuronal and vascular protection. Histol Histopathol. 2001 Apr;16(2):633-44.

Woodruff-Pak DS. Eyeblink classical conditioning differentiates normal aging from Alzheimer's disease. Integr Physiol Behav Sci. 2001 Apr-Jun;36(2):87-108.

Veech RL, Chance B, Kashiwaya Y, Lardy HA, Cahill GF. Ketone bodies, potential therapeutic uses. IUBMB Life. 2001 Apr;51(4):241-7.

Evseev VA, Davydova TV, Mikovskaya OI. Dysregulation in neuroimmunopathology and perspectives of immunotherapy. Bull Exp Biol Med. 2001 Apr;131(4):305-8.

Balasubramanian AS. Amyloid beta peptide processing, insulin degrading enzyme, and butyrylcholinesterase. Neurochem Res. 2001 Apr;26(4):453-6.

Cheng LY, Wang JZ, Gong CX, Pei JJ, Zaidi T, Grundke-Iqbal I, Iqbal K. Multiple forms of phosphatase from human brain: isolation and partial characterization of affi-gel blue nonbinding phosphatase activities. Neurochem Res. 2001 Apr;26(4):425-38.

Karelson E, Bogdanovic N, Garlind A, Winblad B, Zilmer K, Kullisaar T, Vihalemm T, Kairane C, Zilmer M. The cerebrocortical areas in normal brain aging and in Alzheimer's disease: noticeable differences in the lipid peroxidation level and in antioxidant defense. Neurochem Res. 2001 Apr;26(4):353-61.

Yen YC, Liu CK, Lung FW, Chong MY. Apolipoprotein E polymorphism and Alzheimer's disease. Kaohsiung J Med Sci. 2001 Apr;17(4):190-7.

Farooqu AA, Horrocks LA. Plasmalogens, phospholipase A2, and docosahexaenoic acid turnover in brain tissue. J Mol Neurosci. 2001 Apr-Jun;16(2-3):263-72; discussion 279-84.

Matsuda H. Cerebral blood flow and metabolic abnormalities in Alzheimer's disease. Ann Nucl Med. 2001 Apr;15(2):85-92.

Singh M. Ovarian hormones elicit phosphorylation of Akt and extracellular-signal regulated kinase in explants of the cerebral cortex. Endocrine. 2001 Apr;14(3):407-15.

Greenlee W, Clader J, Asberom T, McCombie S, Ford J, Guzik H, Kozlowski J, Li S, Liu C, Lowe D, Vice S, Zhao H, Zhou G, Billard W, Binch H, Crosby R, Duffy R, Lachowicz J, Coffin V, Watkins R, Ruperto V, Strader C, Taylor L, Cox K. Muscarinic agonists and antagonists in the treatment of Alzheimer's disease. Farmaco. 2001 Apr;56(4):247-50.

Korovaitseva GI, Shcherbatykh TV, Selezneva NV, Gavrilova SI, Golimbet VE, Voskresenskaia NI, Rogachev EI. [Genetic association between the apolipoprotein E (ApoE) gene alleles and various forms of Alzheimer's disease] Genetika. 2001 Apr;37(4):529-35.

Seltzer B, Vasterling JJ, Mathias CW, Brennan A. Clinical and neuropsychological correlates of impaired awareness of deficits in Alzheimer disease and Parkinson disease: a comparative study. Neuropsychiatry Neuropsychol Behav Neurol. 2001 Apr-Jun;14(2):122-9.

Ferrer I. [Alpha-synucleinopathies] Neurologia. 2001 Apr;16(4):163-70.

Gregersen N, Bross P, Andrese BS, Pedersen CB, Corydon TJ, Bolund L. The role of chaperone-assisted folding and quality control in inborn errors of metabolism: protein folding disorders. J Inherit Metab Dis. 2001 Apr;24(2):189-212.

Liang Y, Belford S, Tang F, Prokai L, Simpkins JW, Hughes JA. Membrane fluidity effects of estratrienes. Brain Res Bull. 2001 Apr;54(6):661-8.

Aisen PS, Marin DB, Brickman AM, Santoro J, Fusco M. Pilot tolerability studies of hydroxychloroquine and colchicine in Alzheimer disease. Alzheimer Dis Assoc Disord. 2001 Apr-Jun;15(2):96-101.

Goldman WP, Morris JC. Evidence that age-associated memory impairment is not a normal variant of aging. Alzheimer Dis Assoc Disord. 2001 Apr-Jun;15(2):72-9.

Whitehouse PJ. The end of Alzheimer disease. Alzheimer Dis Assoc Disord. 2001 Apr-Jun;15(2):59-62.

Momcilovic B, Alkhatib HA, Duerre JA, Cooley M, Long WM, Harris TR, Lykken GI. Environmental lead-210 and bismuth-210 accrue selectively in the brain proteins in Alzheimer disease and brain lipids in Parkinson disease. Alzheimer Dis Assoc Disord. 2001 Apr-Jun;15(2):106-15.

Yang Q, Williams D, Owusu-Ababio G, Ebube NK, Habib MJ. Controlled release tacrine delivery system for the treatment of Alzheimer's disease. Drug Deliv. 2001 Apr-Jun;8(2):93-8.

Hannequin D, Campion D. [Dominant forms of Alzheimer's disease: from genotype to phenotype] Rev Neurol (Paris). 2001 Apr;157(4):384-92.

Eustache F, Desgranges B, de la Sayette V, Lalevée C, Giffard B, Piolino P, Viader F, Baron JC. [Contribution of positron emission tomography to functional neuroimaging in Alzheimer's disease] Rev Neurol (Paris). 2001 Apr;157(4):377-83.

Schönknecht P, Pantel J, Schröder J. [Quantitative magnetic resonance tomography in diagnosis of Alzheimer dementia] Z Gerontol Geriatr. 2001 Apr;34(2):101-7.

Yen YC, Liu CK, Lung FW, Chong MY. Apolipoprotein E polymorphism and Alzheimer's disease. Gaoxiong Yi Xue Ke Xue Za Zhi. 2001 Apr;17(4):190-7.

Trojanowski JQ. Alzheimer's disease centers and the dementias of aging program of the national institute on aging: a brief overview. J Alzheimers Dis. 2001 Apr;3(2):249-251.

Tekirian TL. Commentary: Abeta N- Terminal Isoforms: Critical contributors in the course of AD pathophysiology. J Alzheimers Dis. 2001 Apr;3(2):241-248.

Chui DH, Dobo E, Makifuchi T, Akiyama H, Kawakatsu S, Petit A, Checler F, Araki W, Takahashi K, Tabira T. Apoptotic neurons in Alzheimer's disease frequently show intracellular Abeta42 labeling. J Alzheimers Dis. 2001 Apr;3(2):231-239.

Buxbaum JD, Geoghagen NS, Friedhoff LT. Cholesterol depletion with physiological concentrations of a statin decreases the formation of the Alzheimer amyloid Abeta peptide. J Alzheimers Dis. 2001 Apr;3(2):221-229.

Fonte J, Miklossy J, Atwood C, Martins R. The severity of cortical Alzheimer's type changes is positively correlated with increased amyloid-beta Levels: Resolubilization of amyloid-beta with transition metal ion chelators. J Alzheimers Dis. 2001 Apr;3(2):209-219.

Tomashevski A, Husseman J, Jin LW, Nochlin D, Vincent I. Constitutive Wee1 activity in adult brain neurons with M phase-type alterations in Alzheimer neurodegeneration. J Alzheimers Dis. 2001 Apr;3(2):195-207.

Wolozin B. Peering into proteolysis with presenilins. J Alzheimers Dis. 2001 Apr;3(2):191-193.

Pellegrini L, Passer BJ, Canelles M, Lefterov I, Ganjei JK, Fowlkes BJ, Koonin EV, D'Adamio L. PAMP and PARL, two novel putative metalloproteases interacting with the COOH-terminus of Presenilin-1 and -2. J Alzheimers Dis. 2001 Apr;3(2):181-190.

Lasn H, Winblad B, Bogdanovic N. The number of neurons in the inferior olivary nucleus in Alzheimer's disease and normal aging: A stereological study using the optical fractionator. J Alzheimers Dis. 2001 Apr;3(2):159-168.

De Bree F. Neuropeptides in the therapy of Alzheimer's disease. Drug News Perspect. 2001 Apr;14(3):151-7.

Sun AY, Draczynska-Lusiak B, Sun GY. Oxidized lipoproteins, beta amyloid peptides and Alzheimer's disease. Neurotox Res. 2001 Apr;3(2):167-78.

McGeer EG, McGeer PL. Innate immunity in Alzheimer's disease: a model for local inflammatory reactions. Mol Interv. 2001 Apr;1(1):22-9.

Moyer BD, Balch WE. A new frontier in pharmacology: the endoplasmic reticulum as a regulated export pathway in health and disease. Expert Opin Ther Targets. 2001 Apr;5(2):165-76.

Kaplan GA, Turrell G, Lynch JW, Everson SA, Helkala EL, Salonen JT. Childhood socioeconomic position and cognitive function in adulthood. Int J Epidemiol. 2001 Apr;30(2):256-63.

Yoo BC, Vlkolinsky R, Engidawork E, Cairns N, Fountoulakis M, Lubec G. Differential expression of molecular chaperones in brain of patients with Down syndrome. Electrophoresis. 2001 Apr;22(6):1233-41.

Raina AK, Hochman A, Zhu X, Rottkamp CA, Nunomura A, Siedlak SL, Boux H, Castellani RJ, Perry G, Smith MA. Abortive apoptosis in Alzheimer's disease. Acta Neuropathol (Berl). 2001 Apr 1;101(4):305-10.

Ptok U, Papassotiropoulos A, Maier W, Heun R. Seasonal distribution of births in patients with Alzheimer's disease and elderly depressive patients. Eur Psychiatry. 2001 Apr;16(3):157-61.

Simon DK, Lin MT, Ahn CH, Liu GJ, Gibson GE, Beal MF, Johns DR. Low mutational burden of individual acquired mitochondrial DNA mutations in brain. Genomics. 2001 Apr 1;73(1):113-6.

Zhou RH, Kokame K, Tsukamoto Y, Yutani C, Kato H, Miyata T. Characterization of the human NDRG gene family: a newly identified member, NDRG4, is specifically expressed in brain and heart. Genomics. 2001 Apr 1;73(1):86-97.

Abe K, Saito H. Effects of basic fibroblast growth factor on central nervous system functions. Pharmacol Res. 2001 Apr;43(4):307-12.

Froehlich TE, Bogardus ST, Inouye SK. Dementia and race: are there differences between African Americans and Caucasians? J Am Geriatr Soc. 2001 Apr;49(4):477-84.

Nguyen MD, Larivière RC, Julien JP. Deregulation of Cdk5 in a mouse model of ALS: toxicity alleviated by perikaryal neurofilament inclusions. Neuron. 2001 Apr;30(1):135-47.

Banaclocha MM. Therapeutic potential of N-acetylcysteine in age-related mitochondrial neurodegenerative diseases. Med Hypotheses. 2001 Apr;56(4):472-7.

Zhang JG, Yang JG, Lin ZX, He L, Feng GY, Ma XY, Wang CF, Lu PF, Song SB, Dong XZ, St Clair D, Breen G. Apolipoprotein E epsilon4 allele is a risk factor for late-onset Alzheimer's disease and vascular dementia in Han Chinese. Int J Geriatr Psychiatry. 2001 Apr;16(4):438-9.

Engelborghs S, De Deyn PP. Biological and genetic markers of sporadic Alzheimer's disease. Acta Med Okayama. 2001 Apr;55(2):55-63.

Mielke R, Schopphoff HH, Kugel H, Pietrzyk U, Heindel W, Kessler J, Heiss WD. Relation between 1H MR spectroscopic imaging and regional cerebral glucose metabolism in Alzheimer's disease. Int J Neurosci. 2001 Apr;107(3-4):233-45.

Bundgaard MJ, Regeur L, Gundersen HJ, Pakkenberg B. Size of neocortical neurons in control subjects and in Alzheimer's disease. J Anat. 2001 Apr;198(Pt 4):481-9.

Watson JM, Balota DA, Sergent-Marshall SD. Semantic, phonological, and hybrid veridical and false memories in healthy older adults and in individuals with dementia of the Alzheimer type. Neuropsychology. 2001 Apr;15(2):254-67.

Budson AE, Desikan R, Daffner KR, Schacter DL. Perceptual false recognition in Alzheimer's disease. Neuropsychology. 2001 Apr;15(2):230-43.

Caine D, Hodges JR. Heterogeneity of semantic and visuospatial deficits in early Alzheimer's disease. Neuropsychology. 2001 Apr;15(2):155-64.

Harper DG, Stopa EG, McKee AC, Satlin A, Harlan PC, Goldstein R, Volicer L. Differential circadian rhythm disturbances in men with Alzheimer disease and frontotemporal degeneration. Arch Gen Psychiatry. 2001 Apr;58(4):353-60.

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