Dementia-Alzheimer’s Research Papers ~ May 2000

Dementia-Alzheimer’s Research Papers ~ May 2000

Small GW, Ercoli LM, Silverman DH, Huang SC, Komo S, Bookheimer SY, Lavretsky H, Miller K, Siddarth P, Rasgon NL, Mazziotta JC, Saxena S, Wu HM, Mega MS, Cummings JL, Saunders AM, Pericak-Vance MA, Roses AD, Barrio JR, Phelps ME. Cerebral metabolic and cognitive decline in persons at genetic risk for Alzheimer's disease. Proc Natl Acad Sci U S A. 2000 May 23;97(11):6037-42.

  

Hurtig HI, Trojanowski JQ, Galvin J, Ewbank D, Schmidt ML, Lee VM, Clark CM, Glosser G, Stern MB, Gollomp SM, Arnold SE. Alpha-synuclein cortical Lewy bodies correlate with dementia in Parkinson's disease. Neurology. 2000 May 23;54(10):1916-21.

Cribbs DH, Azizeh BY, Cotman CW, Laferla FM. Fibril formation and neurotoxicity by a herpes simplex virus glycoprotein B fragment with homology to the Alzheimer's A beta peptide. Biochemistry. 2000 May 23;39(20):5988-94.

Baskin F, Rosenberg RN, Iyer L, Hynan L, Cullum CM. Platelet APP isoform ratios correlate with declining cognition in AD. Neurology. 2000 May 23;54(10):1907-9. ,

Hock C, Heese K, Müller-Spahn F, Huber P, Riesen W, Nitsch RM, Otten U. Increased CSF levels of nerve growth factor in patients with Alzheimer's disease. Neurology. 2000 May 23;54(10):2009-11. ,

Carcenac D, Martin-Hunyadi C, Kiesmann M, Demuynck-Roegel C, Alt M, Kuntzmann F. [Extra-pyramidal syndrome induced by donepezil] Presse Med. 2000 May 20;29(18):992-3.

Yasojima K, Kuret J, DeMaggio AJ, McGeer E, McGeer PL. Casein kinase 1 delta mRNA is upregulated in Alzheimer disease brain. Brain Res. 2000 May 19;865(1):116-20.

Tanino H, Shimohama S, Sasaki Y, Sumida Y, Fujimoto S. Increase in phospholipase C-delta1 protein levels in aluminum-treated rat brains. Biochem Biophys Res Commun. 2000 May 19;271(3):620-5.

  

Lee MS, Kwon YT, Li M, Peng J, Friedlander RM, Tsai LH. Neurotoxicity induces cleavage of p35 to p25 by calpain. Nature. 2000 May 18;405(6784):360-4.

 

  

Leissring MA, Akbari Y, Fanger CM, Cahalan MD, Mattson MP, Laferla FM. Capacitative calcium entry deficits and elevated luminal calcium content in mutant presenilin-1 knockin mice. J Cell Biol. 2000 May 15;149(4):793-8.

Kawahara M, Kuroda Y, Arispe N, Rojas E. Alzheimer's beta-amyloid, human islet amylin, and prion protein fragment evoke intracellular free calcium elevations by a common mechanism in a hypothalamic GnRH neuronal cell line. J Biol Chem. 2000 May 12;275(19):14077-83.

Baker M, Graff-Radford D, Wavrant DeVrièze F, Graff-Radford N, Petersen RC, Kokmen E, Boeve B, Myllykangas L, Polvikoski T, Sulkava R, Verkoniemmi A, Tienari P, Haltia M, Hardy J, Hutton M, Perez-Tur J. No association between TAU haplotype and Alzheimer's disease in population or clinic based series or in familial disease. Neurosci Lett. 2000 May 12;285(2):147-9. , ,

Pack-Chung E, Meyers MB, Pettingell WP, Moir RD, Brownawell AM, Cheng I, Tanzi RE, Kim TW. Presenilin 2 interacts with sorcin, a modulator of the ryanodine receptor. J Biol Chem. 2000 May 12;275(19):14440-5.

Voelker R. The World in Medicine: Promising Alzheimer Drug. JAMA. 2000 May 10;283(18):2379.

Bieschke J, Giese A, Schulz-Schaeffer W, Zerr I, Poser S, Eigen M, Kretzschmar H. Ultrasensitive detection of pathological prion protein aggregates by dual-color scanning for intensely fluorescent targets. Proc Natl Acad Sci U S A. 2000 May 9;97(10):5468-73.

  

von Bergen M, Friedhoff P, Biernat J, Heberle J, Mandelkow EM, Mandelkow E. Assembly of tau protein into Alzheimer paired helical filaments depends on a local sequence motif ((306)VQIVYK(311)) forming beta structure. Proc Natl Acad Sci U S A. 2000 May 9;97(10):5129-34.

Ferrer I, Blanco R. N-myc and c-myc expression in Alzheimer disease, Huntington disease and Parkinson disease. Brain Res Mol Brain Res. 2000 May 5;77(2):270-6.

Honda K, Sawada H, Kihara T, Urushitani M, Nakamizo T, Akaike A, Shimohama S. Phosphatidylinositol 3-kinase mediates neuroprotection by estrogen in cultured cortical neurons. J Neurosci Res. 2000 May 1;60(3):321-7.

Lyketsos CG, Steinberg M, Tschanz JT, Norton MC, Steffens DC, Breitner JC. Mental and behavioral disturbances in dementia: findings from the Cache County Study on Memory in Aging. Am J Psychiatry. 2000 May;157(5):708-14.

Drouet B, Pinçon-Raymond M, Chambaz J, Pillot T. Molecular basis of Alzheimer's disease. Cell Mol Life Sci. 2000 May 1;57(5):705-15.

Luedecking EK, DeKosky ST, Mehdi H, Ganguli M, Kamboh MI. Analysis of genetic polymorphisms in the transforming growth factor-beta1 gene and the risk of Alzheimer's disease. Hum Genet. 2000 May 1;106(5):565-9. ,

Crawford F, Freeman M, Abdullah L, Schinka J, Gold M, Duara R, Mullan M. No association between the NOS3 codon 298 polymorphism and Alzheimer's disease in a sample from the United States. Ann Neurol. 2000 May 1;47(5):687. ,

Mück-Seler D, Pivac N. TCH-346 (Novartis). IDrugs. 2000 May;3(5):530-5.

Koudinova NV, Koudinov AR, Yavin E. Alzheimer's Abeta1-40 peptide modulates lipid synthesis in neuronal cultures and intact rat fetal brain under normoxic and oxidative stress conditions. Neurochem Res. 2000 May 1;25(5):653-60.

Rupniak HT, Joy KA, Atkin C, Brown G, Barnes JC, Doctrow SR, Malfroy B, Wong T, Anderson IK, Molloy CR, Mills GI, Soden P. Oxidative neuropathology and putative chemical entities for Alzheimer's disease: neuroprotective effects of salen-manganese catalytic anti-oxidants. Neurotox Res. 2000 May;2(2-3):167-78.

Nordberg A. Neuroprotection in Alzheimer's disease - new strategies for treatment. Neurotox Res. 2000 May;2(2-3):157-65.

Pedersen V, Schmidt WJ. The neuroprotectant properties of glutamate antagonists and antiglutamatergic drugs. Neurotox Res. 2000 May;2(2-3):179-204.

Garcia de Yebenes J, Yebenes J, Mena MA. Neurotrophic factors in neurodegenerative disorders: model of Parkinson's disease. Neurotox Res. 2000 May;2(2-3):115-37.

Danysz W, Parsons CG, Mobius HJ, Stoffler A, Quack G. Neuroprotective and symptomatological action of memantine relevant for Alzheimer's disease - a unified glutamatergic hypothesis on the mechanism of action. Neurotox Res. 2000 May;2(2-3):85-97.

Beal MF, Palomo T, Kostrzewa RM, Archer T. Neuroprotective and neurorestorative strategies for neuronal injury. Neurotox Res. 2000 May;2(2-3):71-84.

Thal LJ. Anti-inflammatory drugs and Alzheimer's disease. Neurobiol Aging. 2000 May-Jun;21(3):449-50; discussion 451-3.

Salmon E, Collette F, Degueldre C, Lemaire C, Franck G. Voxel-based analysis of confounding effects of age and dementia severity on cerebral metabolism in Alzheimer's disease. Hum Brain Mapp. 2000 May;10(1):39-48.

Weiner MF, Martin-Cook K, Svetlik DA, Saine K, Foster B, Fontaine CS. The Quality of Life in Late-Stage Dementia (QUALID) Scale. J Am Med Dir Assoc. 2000 May-Jun;1(3):114-6.

Petanceska SS, Seeger M, Checler F, Gandy S. Mutant presenilin 1 increases the levels of Alzheimer amyloid beta-peptide Abeta42 in late compartments of the constitutive secretory pathway. J Neurochem. 2000 May;74(5):1878-84.

Cacabelos R. Pharmacogenomics in Alzheimer's disease. Drug News Perspect. 2000 May;13(4):252-4.

Heitsch H. Bradykinin B(2) receptor as a potential therapeutic target. Drug News Perspect. 2000 May;13(4):213-25.

Boland JP. Chlamydia pneumoniae and cardiovascular disease: current status. W V Med J. 2000 May-Jun;96(3):458.

Murphy DD, Rueter SM, Trojanowski JQ, Lee VM. Synucleins are developmentally expressed, and alpha-synuclein regulates the size of the presynaptic vesicular pool in primary hippocampal neurons. J Neurosci. 2000 May 1;20(9):3214-20.

 

Paterson D, Nordberg A. Neuronal nicotinic receptors in the human brain. Prog Neurobiol. 2000 May;61(1):75-111.

Solano DC, Sironi M, Bonfini C, Solerte SB, Govoni S, Racchi M. Insulin regulates soluble amyloid precursor protein release via phosphatidyl inositol 3 kinase-dependent pathway. FASEB J. 2000 May;14(7):1015-22.

Ho C, Zhou J, Medina M, Goto T, Jacobson M, Bhide PG, Kosik KS. delta-catenin is a nervous system-specific adherens junction protein which undergoes dynamic relocalization during development. J Comp Neurol. 2000 May 1;420(2):261-76.

Berthault D. [Myosotis, and do not forget the Alzheimer patients] Soins Gerontol. 2000 May-Jun;(23):33-5.

Mundt JC, Freed DM, Greist JH. Lay person-based screening for early detection of Alzheimer's disease: development and validation of an instrument. J Gerontol B Psychol Sci Soc Sci. 2000 May;55(3):P163-70.

Murphy DD, Andrews SB. Culture models for the study of estradiol-induced synaptic plasticity. J Neurocytol. 2000 May-Jun;29(5-6):411-7.

Küppers E, Ivanova T, Karolczak M, Beyer C. Estrogen: a multifunctional messenger to nigrostriatal dopaminergic neurons. J Neurocytol. 2000 May-Jun;29(5-6):375-85.

Behl C, Manthey D. Neuroprotective activities of estrogen: an update. J Neurocytol. 2000 May-Jun;29(5-6):351-8.

Messmer BT, Thaler DS. C1q-binding peptides share sequence similarity with C4 and induce complement activation. Mol Immunol. 2000 May;37(7):343-50.

Ueno I, Sakai T, Yamaoka M, Yoshida R, Tsugita A. Analysis of blood plasma proteins in patients with Alzheimer's disease by two-dimensional electrophoresis, sequence homology and immunodetection. Electrophoresis. 2000 May;21(9):1832-45.

Singla AK, Chawla M, Singh A. Nimesulide: some pharmaceutical and pharmacological aspects--an update. J Pharm Pharmacol. 2000 May;52(5):467-86.

Bonarek M, Barberger-Gateau P, Letenneur L, Deschamps V, Iron A, Dubroca B, Dartigues JF. Relationships between cholesterol, apolipoprotein E polymorphism and dementia: a cross-sectional analysis from the PAQUID study. Neuroepidemiology. 2000 May-Jun;19(3):141-8.

Riedel-Heller SG, Schork A, Matschinger H, Angermeyer MC. Recruitment procedures and their impact on the prevalence of dementia. Results from the Leipzig Longitudinal Study of the Aged (LEILA75+). Neuroepidemiology. 2000 May-Jun;19(3):130-40.

Dechering K, Boersma C, Mosselman S. Estrogen receptors alpha and beta: two receptors of a kind? Curr Med Chem. 2000 May;7(5):561-76.

Lorenzo A, Yuan M, Zhang Z, Paganetti PA, Sturchler-Pierrat C, Staufenbiel M, Mautino J, Vigo FS, Sommer B, Yankner BA. Amyloid beta interacts with the amyloid precursor protein: a potential toxic mechanism in Alzheimer's disease. Nat Neurosci. 2000 May 1;3(5):460-4.

 

Shoji M, Kawarabayashi T, Sato M, Sasaki A, Saido TC, Matsubara E, Tomidokoro Y, Kanai M, Shizuka M, Ishiguro K, Ikeda M, Harigaya Y, Okamoto K, Hirai S. Age-related amyloid beta protein accumulation induces cellular death and macrophage activation in transgenic mice. J Pathol. 2000 May 1;191(1):93-101.

Sawada H, Udaka F, Izumi Y, Nishinaka K, Kawakami H, Nakamura S, Kameyama M. Cerebral white matter lesions are not associated with apoE genotype but with age and female sex in Alzheimer's disease. J Neurol Neurosurg Psychiatry. 2000 May;68(5):653-6.

Shoji M, Harigaya Y, Sasaki A, Uéda K, Ishiguro K, Matsubara E, Watanabe M, Ikeda M, Kanai M, Tomidokoro Y, Shizuka M, Amari M, Kosaka K, Nakazato Y, Okamoto K, Hirai S. Accumulation of NACP/alpha-synuclein in lewy body disease and multiple system atrophy. J Neurol Neurosurg Psychiatry. 2000 May;68(5):605-8.

Carantoni M, Zuliani G, Munari MR, D'Elia K, Palmieri E, Fellin R. Alzheimer disease and vascular dementia: relationships with fasting glucose and insulin levels. Dement Geriatr Cogn Disord. 2000 May-Jun;11(3):176-80.

Ott BR, Heindel WC, Whelihan WM, Caron MD, Piatt AL, Noto RB. A single-photon emission computed tomography imaging study of driving impairment in patients with Alzheimer's disease. Dement Geriatr Cogn Disord. 2000 May-Jun;11(3):153-60.

Haupt M, Kurz A, Jänner M. A 2-year follow-up of behavioural and psychological symptoms in Alzheimer's disease. Dement Geriatr Cogn Disord. 2000 May-Jun;11(3):147-52.

Hirono N, Ishii K, Sasaki M, Kitagaki H, Hashimoto M, Imamura T, Tanimukai S, Hanihara T, Kazui H, Mori E. Features of regional cerebral glucose metabolism abnormality in corticobasal degeneration. Dement Geriatr Cogn Disord. 2000 May-Jun;11(3):139-46.

Urakami K, Wada-Isoe K, Wakutani Y, Ikeda K, Ji Y, Yamagata K, Kowa H, Okada A, Adachi Y, Nakashima K. Lipoprotein(a) phenotypes in patients with vascular dementia. Dement Geriatr Cogn Disord. 2000 May-Jun;11(3):135-8.

Larsson E, Passant U, Sundgren PC, Englund E, Brun A, Lindgren A, Gustafson L. Magnetic resonance imaging and histopathology in dementia, clinically of frontotemporal type. Dement Geriatr Cogn Disord. 2000 May-Jun;11(3):123-34.

Ji Y, Urakami K, Wada-Isoe K, Adachi Y, Nakashima K. Estrogen receptor gene polymorphisms in patients with Alzheimer's disease, vascular dementia and alcohol-associated dementia. Dement Geriatr Cogn Disord. 2000 May-Jun;11(3):119-22. ,

Nishiyama M, Kato Y, Hashimoto M, Yukawa S, Omori K. Apolipoprotein E, methylenetetrahydrofolate reductase (MTHFR) mutation and the risk of senile dementia--an epidemiological study using the polymerase chain reaction (PCR) method. J Epidemiol. 2000 May;10(3):163-72. ,

Brieger P, Rohde A. [Comment on "Dementia of the Alzheimer type in women." J. C. Nedoschill. Forschr Neurol Psychiat 67: 441-117, 1999] Fortschr Neurol Psychiatr. 2000 May;68(5):241-2.

Diaz Brinton R, Chen S, Montoya M, Hsieh D, Minaya J, Kim J, Chu HP. The women's health initiative estrogen replacement therapy is neurotrophic and neuroprotective. Neurobiol Aging. 2000 May-Jun;21(3):475-96.

Lorton D, Schaller J, Lala A, De Nardin E. Chemotactic-like receptors and Abeta peptide induced responses in Alzheimer's disease. Neurobiol Aging. 2000 May-Jun;21(3):463-73.

Maurer I, Zierz S, Möller HJ. A selective defect of cytochrome c oxidase is present in brain of Alzheimer disease patients. Neurobiol Aging. 2000 May-Jun;21(3):455-62.

Praticò D, Trojanowski JQ. Inflammatory hypotheses: novel mechanisms of Alzheimer's neurodegeneration and new therapeutic targets? Neurobiol Aging. 2000 May-Jun;21(3):441-5; discussion 451-3.

Raine CS. Inflammation in Alzheimer's disease: a view from the periphery. Neurobiol Aging. 2000 May-Jun;21(3):437-40; discussion 451-3.

Fassbender K, Masters C, Beyreuther K. Alzheimer's disease: an inflammatory disease? Neurobiol Aging. 2000 May-Jun;21(3):433-6; discussion 451-3.

Bales KR, Du Y, Holtzman D, Cordell B, Paul SM. Neuroinflammation and Alzheimer's disease: critical roles for cytokine/Abeta-induced glial activation, NF-kappaB, and apolipoprotein E. Neurobiol Aging. 2000 May-Jun;21(3):427-32; discussion 451-3.

Roses AD. Causes or consequences of inflammation and pathological signs of Alzheimer disease. Neurobiol Aging. 2000 May-Jun;21(3):423-5.

Akiyama H, Barger S, Barnum S, Bradt B, Bauer J, Cole GM, Cooper NR, Eikelenboom P, Emmerling M, Fiebich BL, Finch CE, Frautschy S, Griffin WS, Hampel H, Hull M, Landreth G, Lue L, Mrak R, Mackenzie IR, McGeer PL, O'Banion MK, Pachter J, Pasinetti G, Plata-Salaman C, Rogers J, Rydel R, Shen Y, Streit W, Strohmeyer R, Tooyoma I, van Muiswinkel FL, Veerhuis R, Walker D, Webster S, Wegrzyniak B, Wenk G, Wyss-Coray T. Inflammation and Alzheimer's disease. Neurobiol Aging. 2000 May-Jun;21(3):383-421.