Amyloid Precursor Protein
Amyloid Precursor Protein
Synaptic Plasticity and the Mechanism of Alzheimer's Disease (Research and Perspectives in Alzheimer's Disease)
A biochemical hypothesis - that Alzheimer?s disease (AD) is a progressive cerebral amyloidosis caused by the aggregation of the amyloid b-protein (Ab) - preceded and enabled the discovery of etiologies. This volume serves as a record focused on bringing together investigators at the forefront of elucidating the structure and function of hippocampal synapses with investigators focused on understanding how early assemblies of Ab may compromise some of these synapses.
Hardcover: 183 pages
Company: Springer (2008-02-19)
ISBN: 3540763295
List Price: $149.00
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Intracellular Traffic and Neurodegenerative Disorders (Research and Perspectives in Alzheimer's Disease)
This book explores the role of sub-cellular trafficking in the pathogenesis, treatment and prevention of neurodegenerative diseases. Recent findings point to faulty trafficking as contributing to the dysfunction and degeneration of neurons and neural circuits. Increasingly, research is targeting the mechanisms responsible and means to address them therapeutically. This book investigates the ways in which sub-cellular trafficking pathways play a role both in the pathological accumulation of these misfolded proteins and in attempts to clear them. Because subcellular protein trafficking has an important role in the biology of neuronal function and survival, this also addresses how trophic factors maintain cell: cell interactions and how the underlying mechanisms may be compromised in neurodegenerative diseases. Examples where the use of such trophic factors may provide a way to modify neurodegenerative diseases are investigated.Hardcover: 184 pages
Company: Springer (2008-12-18)
ISBN: 3540879404
List Price: $159.00
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AMYLOID PRECURSOR PROTEIN
Author: Weiming Xia
Paperback:
Company: NY (1980)
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