Amyloid β Peptide

 Amyloid β Peptide

Kumar A, Dogra S, Prakash A. Protective effect of curcumin (Curcuma longa), against aluminium toxicity: Possible behavioral and biochemical alterations in rats. Behav Brain Res. 2009 Dec 28;205(2):384-90. PubMed Abstract

Abbas T, Faivre E, Hölscher C. Impairment of synaptic plasticity and memory formation in GLP-1 receptor KO mice: Interaction between type 2 diabetes and Alzheimer's disease. Behav Brain Res. 2009 Dec 14;205(1):265-71. PubMed Abstract

Quiroz-Baez R, Rojas E, Arias C. Oxidative stress promotes JNK-dependent amyloidogenic processing of normally expressed human APP by differential modification of alpha-, beta- and gamma-secretase expression. Neurochem Int. 2009 Dec;55(7):662-70. PubMed Abstract

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Milton NG, Harris JR. Polymorphism of amyloid-beta fibrils and its effects on human erythrocyte catalase binding. Micron. 2009 Dec;40(8):800-10. PubMed Abstract

Arrázola MS, Varela-Nallar L, Colombres M, Toledo EM, Cruzat F, Pavez L, Assar R, Aravena A, González M, Montecino M, Maass A, Martínez S, Inestrosa NC. Calcium/calmodulin-dependent protein kinase type IV is a target gene of the Wnt/beta-catenin signaling pathway. J Cell Physiol. 2009 Dec;221(3):658-67. PubMed Abstract

Gorham P, Bark N, Björkhem , Meaney S, Crisby M. Platelet Alpha- and Beta- Secretase Activities are not significantly affected by Dementia or Mild Cognitive Impairment in Swedish Patients. Curr Alzheimer Res. 2009 Dec 1; PubMed Abstract

Vestergaard M, Hamada T, Morita M, Takagi M. Cholesterol, Lipids, Amyloid Beta, and Alzheimer's. Curr Alzheimer Res. 2009 Dec 1; PubMed Abstract

Zhang C, Browne A, Kim DY, Tanzi RE. Familial Alzheimer's Disease Mutations in Presenilin 1 Do Not Alter Levels of the Secreted Amyloid-beta Protein Precursor Generated by beta-Secretase Cleavage. Curr Alzheimer Res. 2009 Dec 1; PubMed Abstract

Shytle RD, Bickford PC, Rezai-Zadeh K, Houb L, Zeng J, Tana J, Sanberg PR, Sanberg CD, Roschek B, Fink RC, Alberte RS. Optimized Turmeric Extracts Have Potent Anti-amyloidogenic Effects. Curr Alzheimer Res. 2009 Dec 1; PubMed Abstract

Xu YX, Wang HQ, Yan J, Sun XB, Guo JC, Zhu CQ. Antibody binding to cell surface amyloid precursor protein induces neuronal injury by deregulating the phosphorylation of focal adhesion signaling related proteins. Neurosci Lett. 2009 Nov 20;465(3):276-81. PubMed Abstract

Ahn K, Song JH, Kim DK, Park MH, Jo SA, Koh YH. Ubc9 gene polymorphisms and late-onset Alzheimer's disease in the Korean population: a genetic association study. Neurosci Lett. 2009 Nov 20;465(3):272-5. PubMed Abstract

Levin EC, Acharya NK, Sedeyn JC, Venkataraman V, D'Andrea MR, Wang HY, Nagele RG. Neuronal expression of vimentin in the Alzheimer's disease brain may be part of a generalized dendritic damage-response mechanism. Brain Res. 2009 Nov 17;1298:194-207. PubMed Abstract

Lomoio S, Scherini E, Necchi D. Beta-amyloid overload does not directly correlate with SAPK/JNK activation and tau protein phosphorylation in the cerebellar cortex of Ts65Dn mice. Brain Res. 2009 Nov 10;1297:198-206. PubMed Abstract

Wang Z, Liu Q, Zhang R, Liu S, Xia Z, Hu Y. Catalpol ameliorates beta amyloid-induced degeneration of cholinergic neurons by elevating brain-derived neurotrophic factors. Neuroscience. 2009 Nov 10;163(4):1363-72. PubMed Abstract

Levine H, Ding Q, Walker JA, Voss RS, Augelli-Szafran CE. Clioquinol and other hydroxyquinoline derivatives inhibit Abeta(1-42) oligomer assembly. Neurosci Lett. 2009 Nov 6;465(1):99-103. PubMed Abstract

Harris B, Pereira I, Parkin E. Targeting ADAM10 to lipid rafts in neuroblastoma SH-SY5Y cells impairs amyloidogenic processing of the amyloid precursor protein. Brain Res. 2009 Nov 3;1296:203-15. PubMed Abstract

Juusela P, Tanskanen M, Nieminen A, Uitto VJ, Blåfield H, Kiuru-Enari S. Hereditary gelsolin amyloidosis mimicking Sjögren's syndrome. Clin Rheumatol. 2009 Nov;28(11):1351-4. PubMed Abstract

Shankar GM, Leissring MA, Adame A, Sun X, Spooner E, Masliah E, Selkoe DJ, Lemere CA, Walsh DM. Biochemical and immunohistochemical analysis of an Alzheimer's disease mouse model reveals the presence of multiple cerebral Abeta assembly forms throughout life. Neurobiol Dis. 2009 Nov;36(2):293-302. PubMed Abstract

Endres K, Mitteregger G, Kojro E, Kretzschmar H, Fahrenholz F. Influence of ADAM10 on prion protein processing and scrapie infectiosity in vivo. Neurobiol Dis. 2009 Nov;36(2):233-41. PubMed Abstract

Bierhaus A, Nawroth PP. Multiple levels of regulation determine the role of the receptor for AGE (RAGE) as common soil in inflammation, immune responses and diabetes mellitus and its complications. Diabetologia. 2009 Nov;52(11):2251-63. PubMed Abstract

Kurz A, Perneczky R. Neurobiology of cognitive disorders. Curr Opin Psychiatry. 2009 Nov;22(6):546-51. PubMed Abstract

Ramírez CM, González M, Díaz M, Alonso R, Ferrer I, Santpere G, Puig B, Meyer G, Marin R. VDAC and ERalpha interaction in caveolae from human cortex is altered in Alzheimer's disease. Mol Cell Neurosci. 2009 Nov;42(3):172-83. PubMed Abstract

Squitti R, Zito G. Anti-copper Therapies in Alzheimer's Disease: New Concepts. Recent Pat CNS Drug Discov. 2009 Nov 1; PubMed Abstract

Lin MS, Chen XB, Wang SS, Chang Y, Chen WY. Dynamic fluorescence imaging analysis to investigate the cholesterol recruitment in lipid monolayer during the interaction between beta-amyloid (1-40) and lipid monolayers. Colloids Surf B Biointerfaces. 2009 Nov 1;74(1):59-66. PubMed Abstract

Edison P, Brooks DJ, Turkheimer FE, Archer HA, Hinz R. Strategies for the generation of parametric images of [11C]PIB with plasma input functions considering discriminations and reproducibility. Neuroimage. 2009 Nov 1;48(2):329-38. PubMed Abstract

Carro EM. Therapeutic Approaches of Leptin in Alzheimer's Disease. Recent Pat CNS Drug Discov. 2009 Nov 1; PubMed Abstract

Hall D, Edskes H. A model of amyloid's role in disease based on fibril fracture. Biophys Chem. 2009 Nov;145(1):17-28. PubMed Abstract

Weissmann C, Reyher HJ, Gauthier A, Steinhoff HJ, Junge W, Brandt R. Microtubule binding and trapping at the tip of neurites regulate tau motion in living neurons. Traffic. 2009 Nov;10(11):1655-68. PubMed Abstract

Nakaya T, Kawai T, Suzuki T. Metabolic stabilization of p53 by FE65 in the nuclear matrix of osmotically stressed cells. FEBS J. 2009 Nov;276(21):6364-74. PubMed Abstract

Zhang JJ, Zhang RF, Meng XK. Protective effect of pyrroloquinoline quinone against Abeta-induced neurotoxicity in human neuroblastoma SH-SY5Y cells. Neurosci Lett. 2009 Oct 30;464(3):165-9. PubMed Abstract

Mouton PR, Chachich ME, Quigley C, Spangler E, Ingram DK. Caloric restriction attenuates amyloid deposition in middle-aged dtg APP/PS1 mice. Neurosci Lett. 2009 Oct 30;464(3):184-7. PubMed Abstract

Giuliani F, Vernay A, Leuba G, Schenk F. Decreased behavioral impairments in an Alzheimer mice model by interfering with TNF-alpha metabolism. Brain Res Bull. 2009 Oct 28;80(4-5):302-8. PubMed Abstract

Beeler N, Riederer BM, Waeber G, Abderrahmani A. Role of the JNK-interacting protein 1/islet brain 1 in cell degeneration in Alzheimer disease and diabetes. Brain Res Bull. 2009 Oct 28;80(4-5):274-81. PubMed Abstract

Morita M, Osoda K, Yamazaki M, Shirai F, Matsuoka N, Arakawa H, Nishimura S. Effects of non-steroidal anti-inflammatory drugs on Abeta deposition in Abeta(1-42) transgenic C. elegans. Brain Res. 2009 Oct 27;1295:186-91. PubMed Abstract

Hou JF, Cui J, Yu LC, Zhang Y. Intracellular amyloid induces impairments on electrophysiological properties of cultured human neurons. Neurosci Lett. 2009 Oct 25;462(3):294-9. PubMed Abstract

Peng Y, Xing C, Xu S, Lemere CA, Chen G, Liu B, Wang L, Feng Y, Wang X. l-3-n-butylphthalide improves cognitive impairment induced by intracerebroventricular infusion of amyloid-beta peptide in rats. Eur J Pharmacol. 2009 Oct 25;621(1-3):38-45. PubMed Abstract

Nielsen AL. The coat protein complex II, COPII, protein Sec13 directly interacts with presenilin-1. Biochem Biophys Res Commun. 2009 Oct 23;388(3):571-5. PubMed Abstract

Ono M, Watanabe R, Kawashima H, Cheng Y, Kimura H, Watanabe H, Haratake M, Saji H, Nakayama M. Fluoro-pegylated Chalcones as Positron Emission Tomography Probes for in Vivo Imaging of beta-Amyloid Plaques in Alzheimer's Disease. J Med Chem. 2009 Oct 22;52(20):6394-401. PubMed Abstract

Raymond SB, Kumar AT, Boas DA, Bacskai BJ. Optimal parameters for near infrared fluorescence imaging of amyloid plaques in Alzheimer's disease mouse models. Phys Med Biol. 2009 Oct 21;54(20):6201-16. PubMed Abstract

Li Q, Zhao HF, Zhang ZF, Liu ZG, Pei XR, Wang JB, Li Y. Long-term green tea catechin administration prevents spatial learning and memory impairment in senescence-accelerated mouse prone-8 mice by decreasing Abeta1-42 oligomers and upregulating synaptic plasticity-related proteins in the hippocampus. Neuroscience. 2009 Oct 20;163(3):741-9. PubMed Abstract

Kitaguchi H, Tomimoto H, Ihara M, Shibata M, Uemura K, Kalaria RN, Kihara T, Asada-Utsugi M, Kinoshita A, Takahashi R. Chronic cerebral hypoperfusion accelerates amyloid beta deposition in APPSwInd transgenic mice. Brain Res. 2009 Oct 19;1294:202-10. PubMed Abstract

Mancino AM, Hindo SS, Kochi A, Lim MH. Effects of clioquinol on metal-triggered amyloid-beta aggregation revisited. Inorg Chem. 2009 Oct 19;48(20):9596-8. PubMed Abstract

Annies M, Stefani M, Hueber A, Fischer F, Paganetti P. Splicing of intron 3 of human BACE requires the flanking introns 2 and 4. Biochem Biophys Res Commun. 2009 Oct 16;388(2):434-8. PubMed Abstract

Park SA, Shaked GM, Bredesen DE, Koo EH. Mechanism of cytotoxicity mediated by the C31 fragment of the amyloid precursor protein. Biochem Biophys Res Commun. 2009 Oct 16;388(2):450-5. PubMed Abstract

Liao MC, Ahmed M, Smith SO, Van Nostrand WE. Degradation of amyloid beta protein by purified myelin basic protein. J Biol Chem. 2009 Oct 16;284(42):28917-25. PubMed Abstract

Pardossi-Piquard R, Böhm C, Chen F, Kanemoto S, Checler F, Schmitt-Ulms G, St George-Hyslop P, Fraser PE. TMP21 transmembrane domain regulates gamma-secretase cleavage. J Biol Chem. 2009 Oct 16;284(42):28634-41. PubMed Abstract

Eggert S, Midthune B, Cottrell B, Koo EH. Induced Dimerization of the Amyloid Precursor Protein Leads to Decreased Amyloid-{beta} Protein Production. J Biol Chem. 2009 Oct 16;284(42):28943-28952. PubMed Abstract

Manczak M, Mao P, Nakamura K, Bebbington C, Park B, Reddy PH. Neutralization of granulocyte macrophage colony-stimulating factor decreases amyloid beta 1-42 and suppresses microglial activity in a transgenic mouse model of Alzheimer's disease. Hum Mol Genet. 2009 Oct 15;18(20):3876-93. PubMed Abstract

Kim M, Suh J, Romano D, Truong MH, Mullin K, Hooli B, Norton D, Tesco G, Elliott K, Wagner SL, Moir RD, Becker KD, Tanzi RE. Potential late-onset Alzheimer's disease-associated mutations in the ADAM10 gene attenuate {alpha}-secretase activity. Hum Mol Genet. 2009 Oct 15;18(20):3987-96. PubMed Abstract