Beta Amyloid Peptide: Research Paper : Hippocampal Volume and Amyloid PET Status Three Years After Ischemic Stroke: A Pilot Study

Hippocampal Volume and Amyloid PET Status Three Years After Ischemic Stroke: A Pilot Study

Abstract

Hippocampal atrophy is seen in many neurodegenerative disorders and may be a cardinal feature of vascular neurodegeneration. We examined hippocampal volume (HV) in a group of ischemic stroke survivors with amyloid 18F-NAV4694 PET imaging three years after stroke. We compared HV between the amyloid-positive (n = 4) and amyloid-negative (n = 29) groups, and associations with co-morbidities using Charlson Comorbidity Indices and multi-way ANOVA. Amyloid status was not associated with verbal or visual delayed free recall memory indices or cognitive impairment. We found no association between amyloid status and HV in this group of ischemic stroke survivors.

Keywords: 18F-NAV4694; Amyloid imaging; PET; atrophy; hippocampal volume; ischemic stroke.

This article originally appeared in the "https://pubmed.ncbi.nlm.nih.gov/33554919/" and has their copyrights. We do not claim copyright on the content. This information is for research purposes only. This Blog is made available by publishers for educational purposes only as well as to give you general information and a general understanding , not to provide specific advice. By using this blog site you understand that there is no client relationship between you and the Blog publisher. The Blog should not be used as a substitute for competent research advice.