Alzheimer’s Research Papers Aug 2001

Alzheimer’s Research Papers   

Shimizu-Okabe C, Yousef GM, Diamandis EP, Yoshida S, Shiosaka S, Fahnestock M. Expression of the kallikrein gene family in normal and Alzheimer's disease brain. Neuroreport. 2001 Aug 28;12(12):2747-51.

Yoshiyama Y, Arai K, Hattori T. Enhanced expression of I-kappaB with neurofibrillary pathology in Alzheimer's disease. Neuroreport. 2001 Aug 28;12(12):2641-5.

Ferrarese C, Aliprandi A, Tremolizzo L, Stanzani L, De Micheli A, Dolara A, Frattola L. Increased glutamate in CSF and plasma of patients with HIV dementia. Neurology. 2001 Aug 28;57(4):671-5.

Huang W, Alexander GE, Chang L, Shetty HU, Krasuski JS, Rapoport SI, Schapiro MB. Brain metabolite concentration and dementia severity in Alzheimer's disease: a (1)H MRS study. Neurology. 2001 Aug 28;57(4):626-32.

Feldman H, Gauthier S, Hecker J, Vellas B, Subbiah P, Whalen E, Donepezil MSAD Study Investigators Group. A 24-week, randomized, double-blind study of donepezil in moderate to severe Alzheimer's disease. Neurology. 2001 Aug 28;57(4):613-20.

Kallijärvi J, Haltia M, Baumann MH. Amphoterin includes a sequence motif which is homologous to the Alzheimer's beta-amyloid peptide (Abeta), forms amyloid fibrils in vitro, and binds avidly to Abeta. Biochemistry. 2001 Aug 28;40(34):10032-7.

Turner RT, Koelsch G, Hong L, Castanheira P, Ermolieff J, Ghosh AK, Tang J, Castenheira P, Ghosh A. Subsite specificity of memapsin 2 (beta-secretase): implications for inhibitor design. Biochemistry. 2001 Aug 28;40(34):10001-6.

Cooper JD, Salehi A, Delcroix JD, Howe CL, Belichenko PV, Chua-Couzens J, Kilbridge JF, Carlson EJ, Epstein CJ, Mobley WC. Failed retrograde transport of NGF in a mouse model of Down's syndrome: reversal of cholinergic neurodegenerative phenotypes following NGF infusion. Proc Natl Acad Sci U S A. 2001 Aug 28;98(18):10439-44. ,

Chu Y, Cochran EJ, Bennett DA, Mufson EJ, Kordower JH. Down-regulation of trkA mRNA within nucleus basalis neurons in individuals with mild cognitive impairment and Alzheimer's disease. J Comp Neurol. 2001 Aug 27;437(3):296-307.

Haan J, Bakker E, Bornebroek M, Roos RA. [From gene to disease; amyloid-beta precursor protein gene instrumental in hereditary cerebral amyloid angiopathies] Ned Tijdschr Geneeskd. 2001 Aug 25;145(34):1639-41.

DeLorey TM, Lin RC, McBrady B, He X, Cook JM, Lameh J, Loew GH. Influence of benzodiazepine binding site ligands on fear-conditioned contextual memory. Eur J Pharmacol. 2001 Aug 24;426(1-2):45-54.

Cedazo-Mínguez A, Cowburn RF. Apolipoprotein E isoform-specific disruption of phosphoinositide hydrolysis: protection by estrogen and glutathione. FEBS Lett. 2001 Aug 24;504(1-2):45-9.

  

Götz J, Chen F, Van Dorpe J, Nitsch RM. Formation of neurofibrillary tangles in P301l tau transgenic mice induced by Abeta 42 fibrils. Science. 2001 Aug 24;293(5534):1491-5.

    

  

Lewis J, Dickson DW, Lin WL, Chisholm L, Corral A, Jones G, Yen SH, Sahara N, Skipper L, Yager D, Eckman C, Hardy J, Hutton M, McGowan E. Enhanced neurofibrillary degeneration in transgenic mice expressing mutant tau and APP. Science. 2001 Aug 24;293(5534):1487-91. ,

    

Esler WP, Wolfe MS. A portrait of Alzheimer secretases--new features and familiar faces. Science. 2001 Aug 24;293(5534):1449-54.

 

Mori H, Motoi Y, Kobayashi T, Hasegawa M, Yamamura A, Iwatsubo T, Mizuno Y. Tau accumulation in a patient with pallidonigroluysian atrophy. Neurosci Lett. 2001 Aug 24;309(2):89-92.

Yip CM, Elton EA, Darabie AA, Morrison MR, McLaurin J. Cholesterol, a modulator of membrane-associated Abeta-fibrillogenesis and neurotoxicity. J Mol Biol. 2001 Aug 24;311(4):723-34.

Bhojak TJ, DeKosky ST, Ganguli M, Kamboh MI. Genetic polymorphism in the cathepsin G gene and the risk of Alzheimer's disease. Neurosci Lett. 2001 Aug 24;309(2):138-40. ,

Hovatta O, Ahrlund-Richter L. [Ethical aspects of stem cell research. Legislation and guidelines in Europe] Lakartidningen. 2001 Aug 22;98(34):3515-9.

Riddell DR, Christie G, Hussain I, Dingwall C. Compartmentalization of beta-secretase (Asp2) into low-buoyant density, noncaveolar lipid rafts. Curr Biol. 2001 Aug 21;11(16):1288-93.

Narayanan V, Scarlata S. Membrane binding and self-association of alpha-synucleins. Biochemistry. 2001 Aug 21;40(33):9927-34.

Kirschenbaum F, Hsu SC, Cordell B, McCarthy JV. Glycogen synthase kinase-3beta regulates presenilin 1 C-terminal fragment levels. J Biol Chem. 2001 Aug 17;276(33):30701-7.

  

Klunk WE, Wang Y, Huang GF, Debnath ML, Holt DP, Mathis CA. Uncharged thioflavin-T derivatives bind to amyloid-beta protein with high affinity and readily enter the brain. Life Sci. 2001 Aug 17;69(13):1471-84. ,

 

Kanski J, Drake J, Aksenova M, Engman L, Butterfield DA. Antioxidant activity of the organotellurium compound 3-[4-(N,N-dimethylamino)benzenetellurenyl]propanesulfonic acid against oxidative stress in synaptosomal membrane systems and neuronal cultures. Brain Res. 2001 Aug 17;911(1):12-21.

Harris IM, Harris JA, Caine D. Object orientation agnosia: a failure to find the axis? J Cogn Neurosci. 2001 Aug 15;13(6):800-12.

Ponting CP. Domain homologues of dopamine beta-hydroxylase and ferric reductase: roles for iron metabolism in neurodegenerative disorders? Hum Mol Genet. 2001 Aug 15;10(17):1853-8.

 

Bowen RL. Sex hormones, amyloid protein, and Alzheimer disease. JAMA. 2001 Aug 15;286(7):790-1.

Winterle JS, Mill T, Harris T, Goldbeck RA. Absolute kinetic characterization of 17-beta-estradiol as a radical-scavenging, antioxidant synergist. Arch Biochem Biophys. 2001 Aug 15;392(2):233-44.

Cagnin A, Brooks DJ, Kennedy AM, Gunn RN, Myers R, Turkheimer FE, Jones T, Banati RB. In-vivo measurement of activated microglia in dementia. Lancet. 2001 Aug 11;358(9280):461-7.

 

van Gool WA, Weinstein HC, Scheltens P, Walstra GJ, Scheltens PK. Effect of hydroxychloroquine on progression of dementia in early Alzheimer's disease: an 18-month randomised, double-blind, placebo-controlled study. Lancet. 2001 Aug 11;358(9280):455-60.

 

Jones RW. Inflammation and Alzheimer's disease. Lancet. 2001 Aug 11;358(9280):436-7.

 

Trabace L, Cassano T, Cagiano R, Tattoli M, Pietra C, Steardo L, Kendrick KM, Cuomo V. Effects of ENA713 and CHF2819, two anti-Alzheimer's disease drugs, on rat amino acid levels. Brain Res. 2001 Aug 10;910(1-2):182-6.

Berezovska O, Jack C, Deng A, Gastineau N, Rebeck GW, Hyman BT. Notch1 and amyloid precursor protein are competitive substrates for presenilin1-dependent gamma-secretase cleavage. J Biol Chem. 2001 Aug 10;276(32):30018-23.

 

Mitrasinovic OM, Perez GV, Zhao F, Lee YL, Poon C, Murphy GM. Overexpression of macrophage colony-stimulating factor receptor on microglial cells induces an inflammatory response. J Biol Chem. 2001 Aug 10;276(32):30142-9.

McIlroy SP, Dynan KB, Vahidassr DJ, Lawson JT, Patterson CC, Passmore P. Common polymorphisms in LRP and A2M do not affect genetic risk for Alzheimer disease in Northern Ireland. Am J Med Genet. 2001 Aug 8;105(6):502-6. , ,

Hasegawa H, Nakai M, Tanimukai S, Taniguchi T, Terashima A, Kawamata T, Fukunaga K, Miyamoto E, Misaki K, Mukai H, Tanaka C. Microglial signaling by amyloid beta protein through mitogen-activated protein kinase mediating phosphorylation of MARCKS. Neuroreport. 2001 Aug 8;12(11):2567-71.

Milton NG, Mayor NP, Rawlinson J. Identification of amyloid-beta binding sites using an antisense peptide approach. Neuroreport. 2001 Aug 8;12(11):2561-6.

Botta L, Valli P, Asti A, Perin P, Zucca G, Racchi M, Govoni S, Pascale A. beta amyloid-induced disruption of ionic balance: studies on the isolated frog labyrinth. Neuroreport. 2001 Aug 8;12(11):2493-7.

Fukuhara R, Ikeda M, Nebu A, Kikuchi T, Maki N, Hokoishi K, Shigenobu K, Komori K, Tanabe H. Alteration of rCBF in Alzheimer's disease patients with delusions of theft. Neuroreport. 2001 Aug 8;12(11):2473-6.

Gonzalez-Lima F, Berndt JD, Valla JE, Games D, Reiman EM. Reduced corpus callosum, fornix and hippocampus in PDAPP transgenic mouse model of Alzheimer's disease. Neuroreport. 2001 Aug 8;12(11):2375-9.

Catani M, Cherubini A, Howard R, Tarducci R, Pelliccioli GP, Piccirilli M, Gobbi G, Senin U, Mecocci P. (1)H-MR spectroscopy differentiates mild cognitive impairment from normal brain aging. Neuroreport. 2001 Aug 8;12(11):2315-7.

Santiard-Baron D, Lacoste A, Ellouk-Achard S, Soulié C, Nicole A, Sarasin A, Ceballos-Picot I. The amyloid peptide induces early genotoxic damage in human preneuron NT2. Mutat Res. 2001 Aug 8;479(1-2):113-20.

Soriano S, Lu DC, Chandra S, Pietrzik CU, Koo EH. The amyloidogenic pathway of amyloid precursor protein (APP) is independent of its cleavage by caspases. J Biol Chem. 2001 Aug 3;276(31):29045-50.

 

Miserez AR. [Alzheimer dementia--a disorder of lipoprotein metabolism?] Schweiz Rundsch Med Prax. 2001 Aug 2;90(31-32):1297-9.

Burkman RT, Collins JA, Greene RA. Current perspectives on benefits and risks of hormone replacement therapy. Am J Obstet Gynecol. 2001 Aug;185(2 Suppl):S13-23.

Rice DP, Fillit HM, Max W, Knopman DS, Lloyd JR, Duttagupta S. Prevalence, costs, and treatment of Alzheimer's disease and related dementia: a managed care perspective. Am J Manag Care. 2001 Aug;7(8):809-18.

Nobili F, Vitali P, Calvini P, Bollati F, Girtler N, Delmonte M, Mariani G, Rodriguez G. Clinical correlative evaluation of an iterative method for reconstruction of brain SPECT images. Nucl Med Biol. 2001 Aug;28(6):627-32.

Lampley-Dallas VT. Medications for the treatment of Alzheimer's disease. J Okla State Med Assoc. 2001 Aug;94(8):347-9.

Chung HY, Choi HR, Park HJ, Choi JS, Choi WC. Peroxynitrite scavenging and cytoprotective activity of 2,3,6-tribromo-4,5-dihydroxybenzyl methyl ether from the marine alga Symphyocladia latiuscula. J Agric Food Chem. 2001 Aug;49(8):3614-21.

Brandt R. Cytoskeletal mechanisms of neuronal degeneration. Cell Tissue Res. 2001 Aug;305(2):255-65.

Liu DX, Greene LA. Neuronal apoptosis at the G1/S cell cycle checkpoint. Cell Tissue Res. 2001 Aug;305(2):217-28.

Hobson JP, Coyle JM, Leeds L, Meara RJ. Health professionals knowledge about Alzheimer's disease. Int J Geriatr Psychiatry. 2001 Aug;16(8):822-3.

Polo-Kantola P, Erkkola R. Alzheimer's disease and estrogen replacement therapy--where are we now? Acta Obstet Gynecol Scand. 2001 Aug;80(8):679-82.

Marshall MJ, Hutchinson SA. A critique of research on the use of activities with persons with Alzheimer's disease: a systematic literature review. J Adv Nurs. 2001 Aug;35(4):488-96.

Manthey D, Heck S, Engert S, Behl C. Estrogen induces a rapid secretion of amyloid beta precursor protein via the mitogen-activated protein kinase pathway. Eur J Biochem. 2001 Aug;268(15):4285-91.

Sakaguchi M, Miyazaki M, Kondo T, Namba M. Up-regulation of S100C in normal human fibroblasts in the process of aging in vitro. Exp Gerontol. 2001 Aug;36(8):1317-25.

Joosten E. Homocysteine, vascular dementia and Alzheimer's disease. Clin Chem Lab Med. 2001 Aug;39(8):717-20.

Tsuchiya K, Mitani K, Arai T, Yamada S, Komiya T, Esaki Y, Haga C, Yamanouchi H, Ikeda K. Argyrophilic grain disease mimicking temporal Pick's disease: a clinical, radiological, and pathological study of an autopsy case with a clinical course of 15 years. Acta Neuropathol (Berl). 2001 Aug;102(2):195-9.

Sugarman J, Cain C, Wallace R, Welsh-Bohmer KA. How proxies make decisions about research for patients with Alzheimer's disease. J Am Geriatr Soc. 2001 Aug;49(8):1110-9.

Karlawish JH, Casarett D, Klocinski J, Clark CM. The relationship between caregivers' global ratings of Alzheimer's disease patients' quality of life, disease severity, and the caregiving experience. J Am Geriatr Soc. 2001 Aug;49(8):1066-70.

Lee BF, Liu CK, Tai CT, Chiu NT, Liu GC, Yu HS, Pai MC. Alzheimer's disease: scintigraphic appearance of Tc-99m HMPAO brain SPECT. Kaohsiung J Med Sci. 2001 Aug;17(8):394-400.

Galván M, David JP, Delacourte A, Luna J, Mena R. Sequence of neurofibrillary changes in aging and Alzheimer's disease: A confocal study with phospho-tau antibody, AD2. J Alzheimers Dis. 2001 Aug;3(4):417-425.

Velez-Pardo C, Arroyave ST, Lopera F, Castaño AD, Jimenez Del Rio M. Ultrastructure evidence of necrotic neural cell death in familial Alzheimer's disease brains bearing presenilin-1 E280A mutation. J Alzheimers Dis. 2001 Aug;3(4):409-415.

Luo Y. Ginkgo biloba neuroprotection: Therapeutic implications in Alzheimer's disease. J Alzheimers Dis. 2001 Aug;3(4):401-407.

Figueroa DJ, Shi XP, Gardell SJ, Austin CP. Abetapp secretases are co-expressed with Abetapp in the pancreatic islets. J Alzheimers Dis. 2001 Aug;3(4):393-396.

Ghribi O, DeWitt DA, Forbes MS, Arad A, Herman MM, Savory J. Cyclosporin A inhibits Al-induced cytochrome c release from mitochondria in aged rabbits. J Alzheimers Dis. 2001 Aug;3(4):387-391.

Ranganathan S, Scudiere S, Bowser R. Hyperphosphorylation of the retinoblastoma gene product and altered subcellular distribution of E2F-1 during Alzheimer's disease and amyotrophic lateral sclerosis. J Alzheimers Dis. 2001 Aug;3(4):377-385.

Hughes LF, Struble RG, Shaffer CL. Olfaction in elderly and patients with Alzheimer's disease: Differing feedback conditions. J Alzheimers Dis. 2001 Aug;3(4):367-375.

Stone TW, Behan WM, Jones PA, Darlington LG, Smith RA. The role of kynurenines in the production of neuronal death, and the neuroprotective effect of purines. J Alzheimers Dis. 2001 Aug;3(4):355-366.

Santiago Grisoli;a J. Stem Cell Grafting for Epilepsy: Clinical Promise and Ethical Concerns. . 2001 Aug;2(4):318-323.

Giovannetti T, Lamar M, Cloud BS, Swenson R, Fein D, Kaplan E, Libon DJ. Different underlying mechanisms for deficits in concept formation in dementia. Arch Clin Neuropsychol. 2001 Aug;16(6):547-60.

Zhu H, Yu J, Kindy MS. Inhibition of amyloidosis using low-molecular-weight heparins. Mol Med. 2001 Aug;7(8):517-22.

Grinstead K, Rusted J. Do people with Alzheimer's disease have a disproportionate deficit in functional knowledge? Verbal versus motoric access to semantic memory. Aging Ment Health. 2001 Aug;5(3):295-300.

Janus C, Westaway D. Transgenic mouse models of Alzheimer's disease. Physiol Behav. 2001 Aug;73(5):873-86.

Mattila PM, Röyttä M, Lönnberg P, Marjamäki P, Helenius H, Rinne JO. Choline acetytransferase activity and striatal dopamine receptors in Parkinson's disease in relation to cognitive impairment. Acta Neuropathol (Berl). 2001 Aug;102(2):160-6.

Ferrer I, Puig B, Krupinsk J, Carmona M, Blanco R. Fas and Fas ligand expression in Alzheimer's disease. Acta Neuropathol (Berl). 2001 Aug;102(2):121-31.

Qiao X, Cummins DJ, Paul SM. Neuroinflammation-induced acceleration of amyloid deposition in the APPV717F transgenic mouse. Eur J Neurosci. 2001 Aug;14(3):474-82.

Radau PE, Slomka PJ, Julin P, Svensson L, Wahlund LO. Evaluation of linear registration algorithms for brain SPECT and the errors due to hypoperfusion lesions. Med Phys. 2001 Aug;28(8):1660-8.

Bridi R, Crossetti FP, Steffen VM, Henriques AT. The antioxidant activity of standardized extract of Ginkgo biloba (EGb 761) in rats. Phytother Res. 2001 Aug;15(5):449-51.

Connor LT, Obler LK, Tocco M, Fitzpatrick PM, Albert ML. Effect of socioeconomic status on aphasia severity and recovery. Brain Lang. 2001 Aug;78(2):254-7.

Choi SH, Park CH, Koo JW, Seo JH, Kim HS, Jeong SJ, Lee JH, Kim SS, Suh YH. Memory impairment and cholinergic dysfunction by centrally administered Abeta and carboxyl-terminal fragment of Alzheimer's APP in mice. FASEB J. 2001 Aug;15(10):1816-8.

Post SG. Preventing schizophrenia and Alzheimer disease: comparative ethics. Schizophr Res. 2001 Aug 1;51(1):103-8.

Armstrong RA, Lantos PL, Cairns NJ. The spatial patterns of pathological brain lesions in 12 patients with corticobasal degeneration. Pathophysiology. 2001 Aug;8(1):47-53.

DeVane CL, Nemeroff CB. An evaluation of risperidone drug interactions. J Clin Psychopharmacol. 2001 Aug;21(4):408-16.

Nizetic D. Functional genomics of the Down syndrome. Croat Med J. 2001 Aug;42(4):421-7.

Elsner RJ. Odor threshold, recognition, discrimination and identification in centenarians. Arch Gerontol Geriatr. 2001 Aug;33(1):81-94.

Yu PH. Involvement of cerebrovascular semicarbazide-sensitive amine oxidase in the pathogenesis of Alzheimer's disease and vascular dementia. Med Hypotheses. 2001 Aug;57(2):175-9.

Maurizi CP. Alzheimer's disease: roles for mitochondrial damage, the hydroxyl radical, and cerebrospinal fluid deficiency of melatonin. Med Hypotheses. 2001 Aug;57(2):156-60.

Allison AC. The possible role of vitamin K deficiency in the pathogenesis of Alzheimer's disease and in augmenting brain damage associated with cardiovascular disease. Med Hypotheses. 2001 Aug;57(2):151-5.

Parkkinen L, Soininen H, Laakso M, Alafuzoff I. Alpha-synuclein pathology is highly dependent on the case selection. Neuropathol Appl Neurobiol. 2001 Aug;27(4):314-25.

Rhodin JA, Thomas T. A vascular connection to Alzheimer's disease. Microcirculation. 2001 Aug;8(4):207-20.

Mungas D, Reed BR, Ellis WG, Jagust WJ. The effects of age on rate of progression of Alzheimer disease and dementia with associated cerebrovascular disease. Arch Neurol. 2001 Aug;58(8):1243-7.

Lipton AM, Cullum CM, Satumtira S, Sontag E, Hynan LS, White CL, Bigio EH. Contribution of asymmetric synapse loss to lateralizing clinical deficits in frontotemporal dementias. Arch Neurol. 2001 Aug;58(8):1233-9.

Almeida OP, Waterreus A, Spry N, Corica T, Martins G, Martins RN, Flicker L. Effect of testosterone deprivation on the cognitive performance of a patient with Alzheimer's disease. Int J Geriatr Psychiatry. 2001 Aug;16(8):823-5.

Ueki A, Shinjo H, Shimode H, Nakajima T, Morita Y. Factors associated with mortality in patients with early-onset Alzheimer's disease: a five-year longitudinal study. Int J Geriatr Psychiatry. 2001 Aug;16(8):810-5.

De Vreese LP, Neri M, Fioravanti M, Belloi L, Zanetti O. Memory rehabilitation in Alzheimer's disease: a review of progress. Int J Geriatr Psychiatry. 2001 Aug;16(8):794-809.

Saunders AM. Gene identification in Alzheimer's disease. Pharmacogenomics. 2001 Aug;2(3):239-49.

Kim JH, Kim SI, Song KS. Prolyl endopeptidase inhibitors from green tea. Arch Pharm Res. 2001 Aug;24(4):292-6.

Dierssen M, Fillat C, Crnic L, Arbonés M, Flórez J, Estivill X. Murine models for Down syndrome. Physiol Behav. 2001 Aug;73(5):859-71.

Tomidokoro Y, Harigaya Y, Matsubara E, Ikeda M, Kawarabayashi T, Shirao T, Ishiguro K, Okamoto K, Younkin SG, Shoji M. Brain Abeta amyloidosis in APPsw mice induces accumulation of presenilin-1 and tau. J Pathol. 2001 Aug;194(4):500-6.

Huang Y, Wang KK. The calpain family and human disease. Trends Mol Med. 2001 Aug;7(8):355-62.

Fahnestock M, Michalski B, Xu B, Coughlin MD. The precursor pro-nerve growth factor is the predominant form of nerve growth factor in brain and is increased in Alzheimer's disease. Mol Cell Neurosci. 2001 Aug 1;18(2):210-20.

Farkas E, Luiten PG. Cerebral microvascular pathology in aging and Alzheimer's disease. Prog Neurobiol. 2001 Aug 1;64(6):575-611.

Lee BF, Liu CK, Tai CT, Chiu NT, Liu GC, Yu HS, Pai MC. Alzheimer's disease: scintigraphic appearance of Tc-99m HMPAO brain spect. Kaohsiung J Med Sci. 2001 Aug;17(8):394-400.

Wijk H, Sivik L, Steen B, Berg S. Color and form as support for picture recognition in old age. Aging (Milano). 2001 Aug;13(4):298-308.

Osoegawa M, Takao T, Taniwaki T, Kikuchi H, Arakawa K, Furuya H, Iwaki T, Kira J. [An autopsy case of dementia with motor neuron disease accompanying Alzheimer's disease lesion] Rinsho Shinkeigaku. 2001 Aug;41(8):482-6.

Langley LK, Fuentes LJ, Hochhalter AK, Brandt J, Overmier JB. Inhibition of return in aging and Alzheimer's disease: performance as a function of task demands and stimulus timing. J Clin Exp Neuropsychol. 2001 Aug;23(4):431-46.

Andrikopoulos J. Malingering disorientation to time, personal information, and place in mild head injured litigants. Clin Neuropsychol. 2001 Aug;15(3):393-6.

Kontush A. Alzheimer's amyloid-beta as a preventive antioxidant for brain lipoproteins. Cell Mol Neurobiol. 2001 Aug;21(4):299-315.

Surguchov A, Palazzo RE, Surgucheva I. Gamma synuclein: subcellular localization in neuronal and non-neuronal cells and effect on signal transduction. Cell Motil Cytoskeleton. 2001 Aug;49(4):218-28.

Heath AW. Recent advances in vaccinology. Curr Opin Pharmacol. 2001 Aug;1(4):425-30.

Loeffler DA, Sima AA, LeWitt PA. Ceruloplasmin immunoreactivity in neurodegenerative disorders. Free Radic Res. 2001 Aug;35(2):111-8.

Gil N, Josman N. Memory and metamemory performance in Alzheimer's disease and healthy elderly: the Contextual Memory Test (CMT). Aging (Milano). 2001 Aug;13(4):309-15.

Schneider LS. Assessing outcomes in Alzheimer disease. Alzheimer Dis Assoc Disord. 2001 Aug;15 Suppl 1:S8-18.

Winblad B. Maintaining functional and behavioral abilities in Alzheimer disease. Alzheimer Dis Assoc Disord. 2001 Aug;15 Suppl 1:S34-40.

DeKosky ST, Orgogozo JM. Alzheimer disease: diagnosis, costs, and dimensions of treatment. Alzheimer Dis Assoc Disord. 2001 Aug;15 Suppl 1:S3-7.

Tariot PN. Maintaining cognitive function in Alzheimer disease: how effective are current treatments? Alzheimer Dis Assoc Disord. 2001 Aug;15 Suppl 1:S26-33.

Albuquerque EX, Santos MD, Alkondon M, Pereira EF, Maelicke A. Modulation of nicotinic receptor activity in the central nervous system: a novel approach to the treatment of Alzheimer disease. Alzheimer Dis Assoc Disord. 2001 Aug;15 Suppl 1:S19-25.

Morishima-Kawashima M, Saido TC, Ihara Y. [Alzheimer's disease and the proteins] Tanpakushitsu Kakusan Koso. 2001 Aug;46(11 Suppl):1798-804.

Mcpherson A, Furniss FG, Sdogati C, Cesaroni F, Tartaglini B, Lindesay J. Effects of individualized memory aids on the conversation of persons with severe dementia: a pilot study. Aging Ment Health. 2001 Aug;5(3):289-94.

Pekkonen E, Hirvonen J, Jääskeläinen IP, Kaakkola S, Huttunen J. Auditory sensory memory and the cholinergic system: implications for Alzheimer's disease. Neuroimage. 2001 Aug;14(2):376-82.

Baron JC, Chételat G, Desgranges B, Perchey G, Landeau B, de la Sayette V, Eustache F. In vivo mapping of gray matter loss with voxel-based morphometry in mild Alzheimer's disease. Neuroimage. 2001 Aug;14(2):298-309.

Stéphan A, Laroche S, Davis S. Generation of aggregated beta-amyloid in the rat hippocampus impairs synaptic transmission and plasticity and causes memory deficits. J Neurosci. 2001 Aug 1;21(15):5703-14.

Massi F, Straub JE. Probing the origins of increased activity of the E22Q "Dutch" mutant Alzheimer's beta-amyloid peptide. Biophys J. 2001 Aug;81(2):697-709.

Slack BE, Ma LK, Seah CC. Constitutive shedding of the amyloid precursor protein ectodomain is up-regulated by tumour necrosis factor-alpha converting enzyme. Biochem J. 2001 Aug 1;357(Pt 3):787-94.

Eidenmüller J, Fath T, Maas T, Pool M, Sontag E, Brandt R. Phosphorylation-mimicking glutamate clusters in the proline-rich region are sufficient to simulate the functional deficiencies of hyperphosphorylated tau protein. Biochem J. 2001 Aug 1;357(Pt 3):759-67.

Kontush A, Mann U, Arlt S, Ujeyl A, Lührs C, Müller-Thomsen T, Beisiegel U. Influence of vitamin E and C supplementation on lipoprotein oxidation in patients with Alzheimer's disease. Free Radic Biol Med. 2001 Aug 1;31(3):345-54.

Andorn AC, Pappolla MA. Catecholamines inhibit lipid peroxidation in young, aged, and Alzheimer's disease brain. Free Radic Biol Med. 2001 Aug 1;31(3):315-20.

Pasinetti GM. Cyclooxygenase and Alzheimer's disease: implications for preventive initiatives to slow the progression of clinical dementia. Arch Gerontol Geriatr. 2001 Aug;33(1):13-28.

Giffard B, Desgranges B, Nore-Mary F, Lalevée C, de la Sayette V, Pasquier F, Eustache F. The nature of semantic memory deficits in Alzheimer's disease: new insights from hyperpriming effects. Brain. 2001 Aug;124(Pt 8):1522-32.

Baddeley AD, Baddeley HA, Bucks RS, Wilcock GK. Attentional control in Alzheimer's disease. Brain. 2001 Aug;124(Pt 8):1492-508.

Sala SD, Logie RH. Theoretical and practical implications of dual-task performance in Alzheimer's disease. Brain. 2001 Aug;124(Pt 8):1479-81.

Liepert J, Bär KJ, Meske U, Weiller C. Motor cortex disinhibition in Alzheimer's disease. Clin Neurophysiol. 2001 Aug;112(8):1436-41.

Petrosian AA, Prokhorov DV, Lajara-Nanson W, Schiffer RB. Recurrent neural network-based approach for early recognition of Alzheimer's disease in EEG. Clin Neurophysiol. 2001 Aug;112(8):1378-87.

van Amelsvoort T, Compton J, Murphy D. In vivo assessment of the effects of estrogen on human brain. Trends Endocrinol Metab. 2001 Aug;12(6):273-6.

Liu HC, Hong CJ, Liu CY, Lin KN, Tsai SJ, Liu TY, Chi CW, Wang PN. Association analysis of the 5-HT6 receptor polymorphism C267T with depression in patients with Alzheimer's disease. Psychiatry Clin Neurosci. 2001 Aug;55(4):427-9. ,

Woo SI, Kim JW, Seo HG, Park CH, Han SH, Kim SH, Kim KW, Jhoo JH, Woo JI. CYP2D6*4 polymorphism is not associated with Parkinson's disease and has no protective role against Alzheimer's disease in the Korean population. Psychiatry Clin Neurosci. 2001 Aug;55(4):373-7. ,

Saito H, Yamazaki H, Matsuoka H, Matsumoto K, Numachi Y, Yoshida S, Ueno T, Sato M. Visual event-related potential in mild dementia of the Alzheimer's type. Psychiatry Clin Neurosci. 2001 Aug;55(4):365-71.

Pocernich CB, Cardin AL, Racine CL, Lauderback CM, Butterfield DA. Glutathione elevation and its protective role in acrolein-induced protein damage in synaptosomal membranes: relevance to brain lipid peroxidation in neurodegenerative disease. Neurochem Int. 2001 Aug;39(2):141-9.

Mattson MP, Chan SL, Camandola S. Presenilin mutations and calcium signaling defects in the nervous and immune systems. Bioessays. 2001 Aug 1;23(8):733-44.

Müller WE, Kirsch C, Eckert GP. Membrane-disordering effects of beta-amyloid peptides. Biochem Soc Trans. 2001 Aug;29(Pt 4):617-23.

Johansson J. Membrane properties and amyloid fibril formation of lung surfactant protein C. Biochem Soc Trans. 2001 Aug;29(Pt 4):601-6.

Steiner H, Winkler E, Shearman MS, Prywes R, Haass C. Endoproteolysis of the ER stress transducer ATF6 in the presence of functionally inactive presenilins. Neurobiol Dis. 2001 Aug;8(4):717-22.

Steinhoff T, Moritz E, Wollmer MA, Mohajeri MH, Kins S, Nitsch RM. Increased cystatin C in astrocytes of transgenic mice expressing the K670N-M671L mutation of the amyloid precursor protein and deposition in brain amyloid plaques. Neurobiol Dis. 2001 Aug;8(4):647-54.

White F, Nicoll JA, Roses AD, Horsburgh K. Impaired neuronal plasticity in transgenic mice expressing human apolipoprotein E4 compared to E3 in a model of entorhinal cortex lesion. Neurobiol Dis. 2001 Aug;8(4):611-25.

Poduslo JF, Curran GL, Wengenack TM, Malester B, Duff K. Permeability of proteins at the blood-brain barrier in the normal adult mouse and double transgenic mouse model of Alzheimer's disease. Neurobiol Dis. 2001 Aug;8(4):555-67.

Ruitenberg A, Kalmijn S, de Ridder MA, Redekop WK, van Harskamp F, Hofman A, Launer LJ, Breteler MM. Prognosis of Alzheimer's disease: the Rotterdam Study. Neuroepidemiology. 2001 Aug;20(3):188-95.

Casadei VM, Ferri C, Calabrese E, Grimaldi LM, Franceschi M, Veglia F, Licastro F, Mariani C. Prion protein gene polymorphism and Alzheimer's disease: one modulatory trait of cognitive decline? J Neurol Neurosurg Psychiatry. 2001 Aug;71(2):279-80. ,

De Jonghe C, Esselens C, Kumar-Singh S, Craessaerts K, Serneels S, Checler F, Annaert W, Van Broeckhoven C, De Strooper B. Pathogenic APP mutations near the gamma-secretase cleavage site differentially affect Abeta secretion and APP C-terminal fragment stability. Hum Mol Genet. 2001 Aug 1;10(16):1665-71.

Law A, Gauthier S, Quirion R. Neuroprotective and neurorescuing effects of isoform-specific nitric oxide synthase inhibitors, nitric oxide scavenger, and antioxidant against beta-amyloid toxicity. Br J Pharmacol. 2001 Aug;133(7):1114-24.

Mori T, Paris D, Town T, Rojiani AM, Sparks DL, Delledonne A, Crawford F, Abdullah LI, Humphrey JA, Dickson DW, Mullan MJ. Cholesterol accumulates in senile plaques of Alzheimer disease patients and in transgenic APP(SW) mice. J Neuropathol Exp Neurol. 2001 Aug;60(8):778-85.

 

Nunomura A, Perry G, Aliev G, Hirai K, Takeda A, Balraj EK, Jones PK, Ghanbari H, Wataya T, Shimohama S, Chiba S, Atwood CS, Petersen RB, Smith MA. Oxidative damage is the earliest event in Alzheimer disease. J Neuropathol Exp Neurol. 2001 Aug;60(8):759-67.

Le R, Cruz L, Urbanc B, Knowles RB, Hsiao-Ashe K, Duff K, Irizarry MC, Stanley HE, Hyman BT. Plaque-induced abnormalities in neurite geometry in transgenic models of Alzheimer disease: implications for neural system disruption. J Neuropathol Exp Neurol. 2001 Aug;60(8):753-8.

Sigurdsson EM, Scholtzova H, Mehta PD, Frangione B, Wisniewski T. Immunization with a nontoxic/nonfibrillar amyloid-beta homologous peptide reduces Alzheimer's disease-associated pathology in transgenic mice. Am J Pathol. 2001 Aug;159(2):439-47.

    

Shi J, Ma C, Lao H, Feng R, Guo Y, Mu N, Li Q, Tan Y, Wang D. [No evidence for association between the alpha 2-macroglobulin polymorphism and Alzheimer's disease in the Han Chinese] Zhonghua Yi Xue Yi Chuan Xue Za Zhi. 2001 Aug;18(4):299-302.

Small DH, Mok SS, Bornstein JC. Alzheimer's disease and Abeta toxicity: from top to bottom. Nat Rev Neurosci. 2001 Aug 1;2(8):595-8.

Chen F, Yu G, Arawaka S, Nishimura M, Kawarai T, Yu H, Tandon A, Supala A, Song YQ, Rogaeva E, Milman P, Sato C, Yu C, Janus C, Lee J, Song L, Zhang L, Fraser PE, St George-Hyslop PH. Nicastrin binds to membrane-tethered Notch. Nat Cell Biol. 2001 Aug;3(8):751-4.

  

Alzheimer’s Research Papers April 2001

Alzheimer’s Research Papers     

           

Lachowicz JE, Duffy RA, Ruperto V, Kozlowski J, Zhou G, Clader J, Billard W, Binch H, Crosby G, Cohen-Williams M, Strader CD, Coffin V. Facilitation of acetylcholine release and improvement in cognition by a selective M2 muscarinic antagonist, SCH 72788. Life Sci. 2001 Apr 27;68(22-23):2585-92.

Zhang L, Song L, Terracina G, Liu Y, Pramanik B, Parker E. Biochemical characterization of the gamma-secretase activity that produces beta-amyloid peptides. Biochemistry. 2001 Apr 24;40(16):5049-55.

Sobel RK. A tonic for dementia? Genes for Alzheimer's. US News World Rep. 2001 Apr 23;130(16):54.

Gorman C. Brain games. Alzheimer's gene therapy. Time. 2001 Apr 23;157(16):64.

Kuo YM, Kokjohn TA, Beach TG, Sue LI, Brune D, Lopez JC, Kalback WM, Abramowski D, Sturchler-Pierrat C, Staufenbiel M, Roher AE. Comparative analysis of amyloid-beta chemical structure and amyloid plaque morphology of transgenic mouse and Alzheimer's disease brains. J Biol Chem. 2001 Apr 20;276(16):12991-8.

Kallberg Y, Gustafsson M, Persson B, Thyberg J, Johansson J. Prediction of amyloid fibril-forming proteins. J Biol Chem. 2001 Apr 20;276(16):12945-50.

Aksenov MY, Markesbery WR. Changes in thiol content and expression of glutathione redox system genes in the hippocampus and cerebellum in Alzheimer's disease. Neurosci Lett. 2001 Apr 20;302(2-3):141-5.

Hartlage-Rübsamen M, Apelt J, Schliebs R. Fibrillary beta-amyloid deposits are closely associated with atrophic nitric oxide synthase (NOS)-expressing neurons but do not upregulate the inducible NOS in transgenic Tg2576 mouse brain with Alzheimer pathology. Neurosci Lett. 2001 Apr 20;302(2-3):73-6.

Ki CS, Na DL, Kim HJ, Kim JW. Alpha-1 antichymotrypsin and alpha-2 macroglobulin gene polymorphisms are not associated with Korean late-onset Alzheimer's disease. Neurosci Lett. 2001 Apr 20;302(2-3):69-72. ,

Su JH, Zhao M, Anderson AJ, Srinivasan A, Cotman CW. Activated caspase-3 expression in Alzheimer's and aged control brain: correlation with Alzheimer pathology. Brain Res. 2001 Apr 20;898(2):350-7.

Ingelson M, Fabre SF, Lilius L, Andersen C, Viitanen M, Almkvist O, Wahlund LO, Lannfelt L. Increased risk for frontotemporal dementia through interaction between tau polymorphisms and apolipoprotein E epsilon4. Neuroreport. 2001 Apr 17;12(5):905-9.

Eckert GP, Kirsch C, Mueller WE. Differential effects of lovastatin treatment on brain cholesterol levels in normal and apoE-deficient mice. Neuroreport. 2001 Apr 17;12(5):883-7.

Bleys RL, Cowen T. Innervation of cerebral blood vessels: morphology, plasticity, age-related, and Alzheimer's disease-related neurodegeneration. Microsc Res Tech. 2001 Apr 15;53(2):106-18.

  

Yang Y, Geldmacher DS, Herrup K. DNA replication precedes neuronal cell death in Alzheimer's disease. J Neurosci. 2001 Apr 15;21(8):2661-8.

 

Gasparini L, Gouras GK, Wang R, Gross RS, Beal MF, Greengard P, Xu H. Stimulation of beta-amyloid precursor protein trafficking by insulin reduces intraneuronal beta-amyloid and requires mitogen-activated protein kinase signaling. J Neurosci. 2001 Apr 15;21(8):2561-70.

 

Perry KW, Nisenbaum LK, George CA, Shannon HE, Felder CC, Bymaster FP. The muscarinic agonist xanomeline increases monoamine release and immediate early gene expression in the rat prefrontal cortex. Biol Psychiatry. 2001 Apr 15;49(8):716-25.

Eckert A, Steiner B, Marques C, Leutz S, Romig H, Haass C, Müller WE. Elevated vulnerability to oxidative stress-induced cell death and activation of caspase-3 by the Swedish amyloid precursor protein mutation. J Neurosci Res. 2001 Apr 15;64(2):183-92.

Thompson CA. FDA approves galantamine for Alzheimer's disease. Am J Health Syst Pharm. 2001 Apr 15;58(8):649.

van Den Hurk WH, Willems HJ, Bloemen M, Martens GJ. Novel frameshift mutations near short simple repeats. J Biol Chem. 2001 Apr 13;276(15):11496-8.

Kim H, Bang OY, Jung MW, Ha SD, Hong HS, Huh K, Kim SU, Mook-Jung I. Neuroprotective effects of estrogen against beta-amyloid toxicity are mediated by estrogen receptors in cultured neuronal cells. Neurosci Lett. 2001 Apr 13;302(1):58-62.

 

Schneider I, Reverse D, Dewachter I, Ris L, Caluwaerts N, Kuiperi C, Gilis M, Geerts H, Kretzschmar H, Godaux E, Moechars D, Van Leuven F, Herms J. Mutant presenilins disturb neuronal calcium homeostasis in the brain of transgenic mice, decreasing the threshold for excitotoxicity and facilitating long-term potentiation. J Biol Chem. 2001 Apr 13;276(15):11539-44.

Bodendorf U, Fischer F, Bodian D, Multhaup G, Paganetti P. A splice variant of beta-secretase deficient in the amyloidogenic processing of the amyloid precursor protein. J Biol Chem. 2001 Apr 13;276(15):12019-23.

Wolfson C, Wolfson DB, Asgharian M, M'Lan CE, Ostbye T, Rockwood K, Hogan DB, Clinical Progression of Dementia Study Group. A reevaluation of the duration of survival after the onset of dementia. N Engl J Med. 2001 Apr 12;344(15):1111-6.

Lecerf JM, Shirley TL, Zhu Q, Kazantsev A, Amersdorfer P, Housman DE, Messer A, Huston JS. Human single-chain Fv intrabodies counteract in situ huntingtin aggregation in cellular models of Huntington's disease. Proc Natl Acad Sci U S A. 2001 Apr 10;98(8):4764-9.

Liu Q, Kawai H, Berg DK. beta -Amyloid peptide blocks the response of alpha 7-containing nicotinic receptors on hippocampal neurons. Proc Natl Acad Sci U S A. 2001 Apr 10;98(8):4734-9.

Jagust W, Thisted R, Devous MD, Van Heertum R, Mayberg H, Jobst K, Smith AD, Borys N. SPECT perfusion imaging in the diagnosis of Alzheimer's disease: a clinical-pathologic study. Neurology. 2001 Apr 10;56(7):950-6.

Sagara Y, Everall IP, Mallory M, Everson A, Langford D, Masliah E. Fibroblast growth factor 1 regulates signaling via the GSK3{beta} pathway: implications for neuroprotection. J Biol Chem. 2001 Apr 9;

Benjannet S, Elagoz A, Wickham L, Mamarbachi M, Munzer JS, Basak A, Lazure C, Cromlish JA, Sisodia S, Checler F, Chrétien M, Seidah NG. Post-translational processing of beta-secretase (beta-amyloid-converting enzyme) and its ectodomain shedding. The pro- and transmembrane/cytosolic domains affect its cellular activity and amyloid-beta production. J Biol Chem. 2001 Apr 6;276(14):10879-87.

 

Schupf N, Patel B, Silverman W, Zigman WB, Zhong N, Tycko B, Mehta PD, Mayeux R. Elevated plasma amyloid beta-peptide 1-42 and onset of dementia in adults with Down syndrome. Neurosci Lett. 2001 Apr 6;301(3):199-203.

Smits HA, de Vos NM, Wat JW, van der Bruggen T, Verhoef J, Nottet HS. Intracellular pathways involved in TNF-alpha and superoxide anion release by Abeta(1-42)-stimulated primary human macrophages. J Neuroimmunol. 2001 Apr 2;115(1-2):144-51.

Sramek JJ, Veroff AE, Cutler NR. The status of ongoing trials for mild cognitive impairment. Expert Opin Investig Drugs. 2001 Apr;10(4):741-52.

Jhee S, Shiovitz T, Crawford AW, Cutler NR. Beta-amyloid therapies in Alzheimer's disease. Expert Opin Investig Drugs. 2001 Apr;10(4):593-605.

Szczepanik AM, Rampe D, Ringheim GE. Amyloid-beta peptide fragments p3 and p4 induce pro-inflammatory cytokine and chemokine production in vitro and in vivo. J Neurochem. 2001 Apr;77(1):304-17.

Troy CM, Rabacchi SA, Xu Z, Maroney AC, Connors TJ, Shelanski ML, Greene LA. beta-Amyloid-induced neuronal apoptosis requires c-Jun N-terminal kinase activation. J Neurochem. 2001 Apr;77(1):157-64.

Cheng CM, Cohen M, Wang J, Bondy CA. Estrogen augments glucose transporter and IGF1 expression in primate cerebral cortex. FASEB J. 2001 Apr;15(6):907-15.

King ME, Ghoshal N, Wall JS, Binder LI, Ksiezak-Reding H. Structural analysis of Pick's disease-derived and in vitro-assembled tau filaments. Am J Pathol. 2001 Apr;158(4):1481-90.

 

Matsuoka Y, Picciano M, Malester B, LaFrancois J, Zehr C, Daeschner JM, Olschowka JA, Fonseca MI, O'Banion MK, Tenner AJ, Lemere CA, Duff K. Inflammatory responses to amyloidosis in a transgenic mouse model of Alzheimer's disease. Am J Pathol. 2001 Apr;158(4):1345-54.

 

Grady CL, Furey ML, Pietrini P, Horwitz B, Rapoport SI. Altered brain functional connectivity and impaired short-term memory in Alzheimer's disease. Brain. 2001 Apr;124(Pt 4):739-56.

Gainotti G, Marra C, Villa G. A double dissociation between accuracy and time of execution on attentional tasks in Alzheimer's disease and multi-infarct dementia. Brain. 2001 Apr;124(Pt 4):731-8.

Murre JM, Graham KS, Hodges JR. Semantic dementia: relevance to connectionist models of long-term memory. Brain. 2001 Apr;124(Pt 4):647-75.

Yon JM. Protein folding: a perspective for biology, medicine and biotechnology. Braz J Med Biol Res. 2001 Apr;34(4):419-35.

Kim HC, Kim DK, Choi IJ, Kang KH, Yi SD, Park J, Park YN. Relation of apolipoprotein E polymorphism to clinically diagnosed Alzheimer's disease in the Korean population. Psychiatry Clin Neurosci. 2001 Apr;55(2):115-20.

Furuno T, Kawanishi C, Iseki E, Onishi H, Sugiyama N, Suzuki K, Kosaka K. No evidence of an association between CYP2D6 polymorphisms among Japanese and dementia with Lewy bodies. Psychiatry Clin Neurosci. 2001 Apr;55(2):89-92.

Kergoat H, Kergoat MJ, Justino L, Chertkow H, Robillard A, Bergman H. An evaluation of the retinal nerve fiber layer thickness by scanning laser polarimetry in individuals with dementia of the Alzheimer type. Acta Ophthalmol Scand. 2001 Apr;79(2):187-91.

Malchiodi-Albedi F, Domenici MR, Paradisi S, Bernardo A, Ajmone-Cat MA, Minghetti L. Astrocytes contribute to neuronal impairment in beta A toxicity increasing apoptosis in rat hippocampal neurons. Glia. 2001 Apr 1;34(1):68-72.

Taylor AE, Yip A, Brayne C, Easton D, Evans JG, Xuereb J, Cairns N, Esiri MM, Rubinsztein DC. Genetic association of an LBP-1c/CP2/LSF gene polymorphism with late onset Alzheimer's disease. J Med Genet. 2001 Apr;38(4):232-3. ,

Whalley LJ. Early-onset Alzheimer's disease in Scotland: environmental and familial factors. Br J Psychiatry. 2001 Apr;178(Suppl 40):S53-9.

Ala TA, Hughes LF, Kyrouac GA, Ghobrial MW, Elble RJ. Pentagon copying is more impaired in dementia with Lewy bodies than in Alzheimer's disease. J Neurol Neurosurg Psychiatry. 2001 Apr;70(4):483-8.

Klein WL, Krafft GA, Finch CE. Targeting small Abeta oligomers: the solution to an Alzheimer's disease conundrum? Trends Neurosci. 2001 Apr;24(4):219-24.

Gerlai R. Alzheimer's disease: beta-amyloid hypothesis strengthened! Trends Neurosci. 2001 Apr;24(4):199.

Inagaki C, Hattori N, Kitagawa K, Zeng XT, Yagyu K. Cl(-)-ATPase in rat brain and kidney. J Exp Zool. 2001 Apr 1;289(4):224-31.

Molloy AM, Scott JM. Folates and prevention of disease. Public Health Nutr. 2001 Apr;4(2B):601-9.

Exley C, Korchazhkina OV. Promotion of formation of amyloid fibrils by aluminium adenosine triphosphate (AlATP). J Inorg Biochem. 2001 Apr;84(3-4):215-24.

Belloir B, Kövari E, Surini-Demiri M, Savioz A. Altered apolipoprotein D expression in the brain of patients with Alzheimer disease. J Neurosci Res. 2001 Apr 1;64(1):61-9.

Kantarci K, Jack CR, Xu YC, Campeau NG, O'Brien PC, Smith GE, Ivnik RJ, Boeve BF, Kokmen E, Tangalos EG, Petersen RC. Mild cognitive impairment and Alzheimer disease: regional diffusivity of water. Radiology. 2001 Apr;219(1):101-7.

Schwartz RB. Apparent diffusion coefficient mapping in patients with Alzheimer disease or mild cognitive impairment and in normally aging control subjects: present and future. Radiology. 2001 Apr;219(1):8-9.

Harrison PM, Chan HS, Prusiner SB, Cohen FE. Conformational propagation with prion-like characteristics in a simple model of protein folding. Protein Sci. 2001 Apr;10(4):819-35.

Selkoe DJ. Alzheimer's disease: genes, proteins, and therapy. Physiol Rev. 2001 Apr;81(2):741-66.

 

Dietschy JM, Turley SD. Cholesterol metabolism in the brain. Curr Opin Lipidol. 2001 Apr;12(2):105-12.

 

Yu WH, Fraser PE. S100beta interaction with tau is promoted by zinc and inhibited by hyperphosphorylation in Alzheimer's disease. J Neurosci. 2001 Apr 1;21(7):2240-6.

Montine TJ, Kaye JA, Montine KS, McFarland L, Morrow JD, Quinn JF. Cerebrospinal fluid abeta42, tau, and f2-isoprostane concentrations in patients with Alzheimer disease, other dementias, and in age-matched controls. Arch Pathol Lab Med. 2001 Apr;125(4):510-2. ,

Gyure KA, Durham R, Stewart WF, Smialek JE, Troncoso JC. Intraneuronal abeta-amyloid precedes development of amyloid plaques in Down syndrome. Arch Pathol Lab Med. 2001 Apr;125(4):489-92.

Zhao X, Kuryatov A, Lindstrom JM, Yeh JZ, Narahashi T. Nootropic drug modulation of neuronal nicotinic acetylcholine receptors in rat cortical neurons. Mol Pharmacol. 2001 Apr;59(4):674-83.

Fabre SF, Forsell C, Viitanen M, Sjögren M, Wallin A, Blennow K, Blomberg M, Andersen C, Wahlund LO, Lannfelt L. Clinic-based cases with frontotemporal dementia show increased cerebrospinal fluid tau and high apolipoprotein E epsilon4 frequency, but no tau gene mutations. Exp Neurol. 2001 Apr;168(2):413-8. ,

Vogelsberg-Ragaglia V, Schuck T, Trojanowski JQ, Lee VM. PP2A mRNA expression is quantitatively decreased in Alzheimer's disease hippocampus. Exp Neurol. 2001 Apr;168(2):402-12.

Quinn J, Davis F, Woodward WR, Eckenstein F. Beta-amyloid plaques induce neuritic dystrophy of nitric oxide-producing neurons in a transgenic mouse model of Alzheimer's disease. Exp Neurol. 2001 Apr;168(2):203-12.

Emre M, Qizilbash N. Experimental approaches and drugs in development for the treatment of dementia. Expert Opin Investig Drugs. 2001 Apr;10(4):607-17.

Shiba K, Mori H, Ikeda E, Sumiya H, Tonami N. The potential of radioiodinated (-)-m-iodovesamicol for diagnosing cholinergic deficit dementia. Nucl Med Biol. 2001 Apr;28(3):261-4.

Whalley LJ. Early-onset Alzheimer's disease in Scotland: environmental and familial factors. Br J Psychiatry Suppl. 2001 Apr;40:s53-9.

Ferrer I, Blanco R, Carmona M, Ribera R, Goutan E, Puig B, Rey MJ, Cardozo A, Viñals F, Ribalta T. Phosphorylated map kinase (ERK1, ERK2) expression is associated with early tau deposition in neurones and glial cells, but not with increased nuclear DNA vulnerability and cell death, in Alzheimer disease, Pick's disease, progressive supranuclear palsy and corticobasal degeneration. Brain Pathol. 2001 Apr;11(2):144-58.

Peterson A, Lantz MS, American Association for Geriatric Psychiatry. Is it Alzheimer's? Neuropsychological testing helps to clarify diagnostic puzzle. Geriatrics. 2001 Apr;56(4):58, 61.

Momcilovic B, Alkhatib HA, Duerre JA, Cooley M, Long WM, Harris TR, Lykken GI. Environmental lead-210 and bismuth-210 accrue selectively in the brain proteins in alzheimer disease and brain lipids in parkinson disease. Alzheimer Dis Assoc Disord. 2001 Apr;15(2):106-15.

Aisen PS, Marin DB, Brickman AM, Santoro J, Fusco M. Pilot tolerability studies of hydroxychloroquine and colchicine in alzheimer disease. Alzheimer Dis Assoc Disord. 2001 Apr;15(2):96-101.

Goldman WP, Morris JC. Evidence that age-associated memory impairment is not a normal variant of aging. Alzheimer Dis Assoc Disord. 2001 Apr;15(2):72-9.

Muehlhauser F, Liebl U, Kuehl S, Walter S, Bertsch T, Fassbender K. Aggregation-Dependent interaction of the Alzheimer's beta-amyloid and microglia. Clin Chem Lab Med. 2001 Apr;39(4):313-6.

Hopman-Rock M, Tak EC, Staats PG, Jonker C, Wind AW. [Indicators of early Alzheimer dementia in family practice. Development and validation of the Observation List of Early Symptoms of Dementia (OLD)] Tijdschr Gerontol Geriatr. 2001 Apr;32(2):74-81.

Ishii K, Willoch F, Minoshima S, Drzezga A, Ficaro EP, Cross DJ, Kuhl DE, Schwaiger M. Statistical brain mapping of 18F-FDG PET in Alzheimer's disease: validation of anatomic standardization for atrophied brains. J Nucl Med. 2001 Apr;42(4):548-57.

Grossberg G, Desai A. Review of rivastigmine and its clinical applications in Alzheimer's disease and related disorders. Expert Opin Pharmacother. 2001 Apr;2(4):653-66.

Lawlor BA, McCarron M, Wilson G, McLoughlin M. Temporal lobe-oriented CT scanning and dementia in Down's syndrome. Int J Geriatr Psychiatry. 2001 Apr;16(4):427-9.

Maiese K. The dynamics of cellular injury: transformation into neuronal and vascular protection. Histol Histopathol. 2001 Apr;16(2):633-44.

Woodruff-Pak DS. Eyeblink classical conditioning differentiates normal aging from Alzheimer's disease. Integr Physiol Behav Sci. 2001 Apr-Jun;36(2):87-108.

Veech RL, Chance B, Kashiwaya Y, Lardy HA, Cahill GF. Ketone bodies, potential therapeutic uses. IUBMB Life. 2001 Apr;51(4):241-7.

Evseev VA, Davydova TV, Mikovskaya OI. Dysregulation in neuroimmunopathology and perspectives of immunotherapy. Bull Exp Biol Med. 2001 Apr;131(4):305-8.

Balasubramanian AS. Amyloid beta peptide processing, insulin degrading enzyme, and butyrylcholinesterase. Neurochem Res. 2001 Apr;26(4):453-6.

Cheng LY, Wang JZ, Gong CX, Pei JJ, Zaidi T, Grundke-Iqbal I, Iqbal K. Multiple forms of phosphatase from human brain: isolation and partial characterization of affi-gel blue nonbinding phosphatase activities. Neurochem Res. 2001 Apr;26(4):425-38.

Karelson E, Bogdanovic N, Garlind A, Winblad B, Zilmer K, Kullisaar T, Vihalemm T, Kairane C, Zilmer M. The cerebrocortical areas in normal brain aging and in Alzheimer's disease: noticeable differences in the lipid peroxidation level and in antioxidant defense. Neurochem Res. 2001 Apr;26(4):353-61.

Yen YC, Liu CK, Lung FW, Chong MY. Apolipoprotein E polymorphism and Alzheimer's disease. Kaohsiung J Med Sci. 2001 Apr;17(4):190-7.

Farooqu AA, Horrocks LA. Plasmalogens, phospholipase A2, and docosahexaenoic acid turnover in brain tissue. J Mol Neurosci. 2001 Apr-Jun;16(2-3):263-72; discussion 279-84.

Matsuda H. Cerebral blood flow and metabolic abnormalities in Alzheimer's disease. Ann Nucl Med. 2001 Apr;15(2):85-92.

Singh M. Ovarian hormones elicit phosphorylation of Akt and extracellular-signal regulated kinase in explants of the cerebral cortex. Endocrine. 2001 Apr;14(3):407-15.

Greenlee W, Clader J, Asberom T, McCombie S, Ford J, Guzik H, Kozlowski J, Li S, Liu C, Lowe D, Vice S, Zhao H, Zhou G, Billard W, Binch H, Crosby R, Duffy R, Lachowicz J, Coffin V, Watkins R, Ruperto V, Strader C, Taylor L, Cox K. Muscarinic agonists and antagonists in the treatment of Alzheimer's disease. Farmaco. 2001 Apr;56(4):247-50.

Korovaitseva GI, Shcherbatykh TV, Selezneva NV, Gavrilova SI, Golimbet VE, Voskresenskaia NI, Rogachev EI. [Genetic association between the apolipoprotein E (ApoE) gene alleles and various forms of Alzheimer's disease] Genetika. 2001 Apr;37(4):529-35.

Seltzer B, Vasterling JJ, Mathias CW, Brennan A. Clinical and neuropsychological correlates of impaired awareness of deficits in Alzheimer disease and Parkinson disease: a comparative study. Neuropsychiatry Neuropsychol Behav Neurol. 2001 Apr-Jun;14(2):122-9.

Ferrer I. [Alpha-synucleinopathies] Neurologia. 2001 Apr;16(4):163-70.

Gregersen N, Bross P, Andrese BS, Pedersen CB, Corydon TJ, Bolund L. The role of chaperone-assisted folding and quality control in inborn errors of metabolism: protein folding disorders. J Inherit Metab Dis. 2001 Apr;24(2):189-212.

Liang Y, Belford S, Tang F, Prokai L, Simpkins JW, Hughes JA. Membrane fluidity effects of estratrienes. Brain Res Bull. 2001 Apr;54(6):661-8.

Aisen PS, Marin DB, Brickman AM, Santoro J, Fusco M. Pilot tolerability studies of hydroxychloroquine and colchicine in Alzheimer disease. Alzheimer Dis Assoc Disord. 2001 Apr-Jun;15(2):96-101.

Goldman WP, Morris JC. Evidence that age-associated memory impairment is not a normal variant of aging. Alzheimer Dis Assoc Disord. 2001 Apr-Jun;15(2):72-9.

Whitehouse PJ. The end of Alzheimer disease. Alzheimer Dis Assoc Disord. 2001 Apr-Jun;15(2):59-62.

Momcilovic B, Alkhatib HA, Duerre JA, Cooley M, Long WM, Harris TR, Lykken GI. Environmental lead-210 and bismuth-210 accrue selectively in the brain proteins in Alzheimer disease and brain lipids in Parkinson disease. Alzheimer Dis Assoc Disord. 2001 Apr-Jun;15(2):106-15.

Yang Q, Williams D, Owusu-Ababio G, Ebube NK, Habib MJ. Controlled release tacrine delivery system for the treatment of Alzheimer's disease. Drug Deliv. 2001 Apr-Jun;8(2):93-8.

Hannequin D, Campion D. [Dominant forms of Alzheimer's disease: from genotype to phenotype] Rev Neurol (Paris). 2001 Apr;157(4):384-92.

Eustache F, Desgranges B, de la Sayette V, Lalevée C, Giffard B, Piolino P, Viader F, Baron JC. [Contribution of positron emission tomography to functional neuroimaging in Alzheimer's disease] Rev Neurol (Paris). 2001 Apr;157(4):377-83.

Schönknecht P, Pantel J, Schröder J. [Quantitative magnetic resonance tomography in diagnosis of Alzheimer dementia] Z Gerontol Geriatr. 2001 Apr;34(2):101-7.

Yen YC, Liu CK, Lung FW, Chong MY. Apolipoprotein E polymorphism and Alzheimer's disease. Gaoxiong Yi Xue Ke Xue Za Zhi. 2001 Apr;17(4):190-7.

Trojanowski JQ. Alzheimer's disease centers and the dementias of aging program of the national institute on aging: a brief overview. J Alzheimers Dis. 2001 Apr;3(2):249-251.

Tekirian TL. Commentary: Abeta N- Terminal Isoforms: Critical contributors in the course of AD pathophysiology. J Alzheimers Dis. 2001 Apr;3(2):241-248.

Chui DH, Dobo E, Makifuchi T, Akiyama H, Kawakatsu S, Petit A, Checler F, Araki W, Takahashi K, Tabira T. Apoptotic neurons in Alzheimer's disease frequently show intracellular Abeta42 labeling. J Alzheimers Dis. 2001 Apr;3(2):231-239.

Buxbaum JD, Geoghagen NS, Friedhoff LT. Cholesterol depletion with physiological concentrations of a statin decreases the formation of the Alzheimer amyloid Abeta peptide. J Alzheimers Dis. 2001 Apr;3(2):221-229.

Fonte J, Miklossy J, Atwood C, Martins R. The severity of cortical Alzheimer's type changes is positively correlated with increased amyloid-beta Levels: Resolubilization of amyloid-beta with transition metal ion chelators. J Alzheimers Dis. 2001 Apr;3(2):209-219.

Tomashevski A, Husseman J, Jin LW, Nochlin D, Vincent I. Constitutive Wee1 activity in adult brain neurons with M phase-type alterations in Alzheimer neurodegeneration. J Alzheimers Dis. 2001 Apr;3(2):195-207.

Wolozin B. Peering into proteolysis with presenilins. J Alzheimers Dis. 2001 Apr;3(2):191-193.

Pellegrini L, Passer BJ, Canelles M, Lefterov I, Ganjei JK, Fowlkes BJ, Koonin EV, D'Adamio L. PAMP and PARL, two novel putative metalloproteases interacting with the COOH-terminus of Presenilin-1 and -2. J Alzheimers Dis. 2001 Apr;3(2):181-190.

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